-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

332.O2.6 332. Thrombosis and Anticoagulation: Clinical and Epidemiological: Thrombotic Risk: The Genes We're Born with and Mutations We Acquire

Symposia: Thrombosis and Anticoagulation: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Bleeding and Clotting, Adult, Acute Myeloid Malignancies, Hodgkin lymphoma, Epidemiology, Elderly, CHIP, MPN, Lymphomas, Non-Hodgkin lymphoma, Clinical Practice (Health Services and Quality), Clinical Research, Genomics, Bioinformatics, Health outcomes research, Genetic Disorders, Thromboembolism, Chronic Myeloid Malignancies, Diseases, Real-world evidence, Thrombotic disorders, Registries, Lymphoid Malignancies, Computational biology, Myeloid Malignancies, Biological Processes, Survivorship, Technology and Procedures, Study Population, Human, Pathogenesis, Omics technologies
Saturday, December 7, 2024: 9:30 AM-11:00 AM
Room 24 (San Diego Convention Center)
Moderators:
Radhika Gangaraju, MD, University Of Alabama and Marie-Claude Pelland-Marcotte, MD, PhD, CHU de Quebec, Centre Mere-Enfant Soleil
Disclosures:
Gangaraju: Sanofi: Consultancy, Honoraria, Research Funding; Alexion: Consultancy; Bayer: Consultancy; Takeda: Consultancy.

Genetics - both germ line and acquired mutations place people at risk for Thrombosis. This session focuses on germ line and somatic mutations and their relationship to thrombosis risk.
9:30 AM

Seyedmohammad Saadatagah, MD1*, Rockbum Kim, MD, PhD2, Senthil Sukumar, MD, MSc2, Md Mesbah Uddin, PhD, MS3*, Aaron R. Folsom4*, Mary Cushman5, Weihong Tang4*, Pradeep Natarajan6,7,8*, Christie M. Ballantyne, MD9*, Pamela Lutsey10* and Ang Li, MD, MS11

1Department of Medicine, Baylor College of Medicine, Houston
2Section of Hematology-Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX
3Massachusetts General Hospital, Cambridge, MA
4University of Minnesota, Minneapolis, MN
5University of Vermont, Burlington, VT
6Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA
7Broad Institute, Boston, MA
8Harvard Medical School, Boston, MA
9Center for Translational Research in Inflammatory Diseases, Baylor College of Medicine, Houston
10University of Minnesota School of Public Health, Minneapolis, MN
11Baylor College of Medicine, Houston, TX

9:45 AM

Radhika Gangaraju, MD1, Yanjun Chen, MS2*, Lindsey Hageman, MPH1*, Elizabeth Ross3*, Liton Francisco1*, David K Crossman4*, Purnima Singh, PhD5*, Alysia Bosworth, BA6*, Daniel Weisdorf, MD7, Ravi Bhatia, MD8, Saro Armenian, DO, MPH6, Stephen J. Forman, MD, FACP9 and Smita Bhatia, MD, MPH1

1Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL
2Institute for Cancer Outcomes and Survivorship, University of Alabama At Birmingham, Birmingham, AL
3University of Alabama at Birmingham, Birmingham, AL
4University of Alabama At Birmingham, Birmingham, AL
5Institute for Cancer Outcomes and Survivorship, University Of Alabama at Birmingham, Birmingham, AL
6City of Hope National Medical Center, Duarte, CA
7University of Minnesota, Minneapolis, MN
8Division of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL
9Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA

10:00 AM

Helen Ajufo, MD, MS1, Avi Leader, MD1, Andriy Derkach, PhD2*, Pavlina Chrysafi, MD3, Rohan Singh, MS4*, Raajit Rampal, MD, PhD5, Simon Mantha, MD, MPH1 and Jeffrey I. Zwicker, MD4

1Hematology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
2Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
3Department of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA
4Memorial Sloan Kettering Cancer Center, New York, NY
5Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

10:15 AM

Chi-Joan How, MD1, Pavlina Chrysafi, MD2, Amica Ko3*, Rebecca Zon, MD4, Atefeh Ghorbanzadeh5*, Dahniel L Sastow, MD6, Maria Georgen7*, Abi Prabhu, MD7*, Vrushali Pachpande8*, Sai Sudha Valisekka8*, Mukul Agarwal, DM, MD, MBBS9*, Amiya Ranjan Nayak10*, May Anne Cheong11*, Alessandra Iurlo, MD, PhD12*, Daniele Cattaneo13*, Thita Chiasakul, MD14*, Rishi Dhawan15*, Kristen M. Sanfilippo, MD16, Gabriela S. Hobbs, MD17, Damon E. Houghton, MD, MS18, Joan D Beckman, MD, PhD19, Lisa Baumann Kreuziger, MD, MS20, Douglas Tremblay, MD21, Rushad Patell, MD22 and Mandy N. Lauw, MD, PhD23

1Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA
2Department of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA
3Erasmus University, Rotterdam, Netherlands
4Brigham and Women's Hospital, Boston
5Mayo Clinic, Rochester, MN
6Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
7Medical College of Wisconsin, Milwaukee
8University of Minnesota, Minneapolis
9Dept of Hematology, All India Institute of Medical Sciences, New Delhi, Delhi, India
10All India Institute Of Medical Sciences, New Delhi, IND
11Singapore General Hospital, Singapore, Singapore
12Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
13FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, MILANO, ITA
14Center of Excellence in Translational Hematology, Division of Hematology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
15All India Institute Of Medical Sciences Delhi, New Delhi, India
16Washington University School of Medicine St Louis, Chesterfield, MO
17Division of Hematology/Oncology, Massachusetts General Hospital, Boston, MA
18Department of Cardiovascular Diseases, Division of Vascular Medicine & Dept of Medicine, Division of Hematology, Mayo Clinic, Rochester, MN
19University of Minnesota, Minneapolis, MN
20Versiti, Menomonee Falls, WI
21Division of Hematology & Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
22Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, Boston, MA
23Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands

10:30 AM

Sharjeel A Chaudhry, MD1,2,3,4*, Amelia K Haj, MD, PhD2,4,5, Justine Ryu, MD4,6, Sean J. Jurgens, MD, MSc4,7,8*, Alfonso Rodriguez Espada, MD4,9*, Xin Wang, MBBS2,4*, Seung Hoan Choi, PhD4*, Simone Sanna-Cherchi, MD10*, Kenneth A Bauer, MD11, Patrick Ellinor, MD, PhD4,7* and Pavan K Bendapudi, MD2,9,12,13

1Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, LAUREL, MD
2Harvard Medical School, Boston, MA
3Division of Cardiology, The Johns Hopkins University, School of Medicine, Baltimore, MD
4The Broad Institute of MIT and Harvard, Cambridge, MA
5Department of Pathology, Massachusetts General Hospital, Cambridge, MA
6Section of Hematology, Yale University School of Medicine, New Haven, CT
7Massachusetts General Hospital, Boston, MA
8Department of Experimental Cardiology, University of Amsterdam, Amsterdam, Netherlands
9Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Boston, MA
10Division of Nephrology, Columbia University Irving Medical School, New York, NY
11Division of Hematology and Hematologic Malignancies, Beth Israel Deaconess Medical Center, Boston, MA
12Division of Hematology, Department of Medicine, Massachusetts General Hospital, Cambridge, MA
13Center for the Development of Therapeutics, The Broad Institute of MIT and Harvard, Cambridge, MA

10:45 AM

Justine Ryu, MD1,2, Sean J. Jurgens, MD, MSc1,3,4*, Satoshi Koyama, MD1*, Leo Wijdeveld5,6*, Joel Rämö, MD, PhD1,7,8*, Amelia K Haj, MD, PhD1,9,10, Xin Wang, MBBS1,10*, Marisa Brake, PhD10, Alfred I Lee, MD, PhD11, Kenneth A Bauer, MD12, Patrick Ellinor, MD, PhD1,3,10* and Pavan K Bendapudi, MD1,10,13

1The Broad Institute of MIT and Harvard, Cambridge, MA
2Section of Hematology, Yale University School of Medicine, New Haven, CT
3Massachusetts General Hospital, Boston, MA
4Department of Experimental Cardiology, University of Amsterdam, Amsterdam, Netherlands
5Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA
6Department of Physiology, Amsterdam University Medical Center, Amsterdam, Netherlands
7Department of Internal Medicine, The Brigham and Women's Hospital, Boston, MA
8Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), Helsinki, Finland
9Department of Pathology, Massachusetts General Hospital, Cambridge, MA
10Harvard Medical School, Boston, MA
11Section of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT
12Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Boston, MA
13Division of Hematology, Department of Medicine, Massachusetts General Hospital, Cambridge, MA

*signifies non-member of ASH