Saifur R. Chowdhury, PhD (c)^1,2*, Emily Sirotich, PhD^3,4, Dimpy Modi^5*, Melanie St John^5*, Kerolos Eisa^5*, Adam Cuker, MD⁶, Carolyn E Beck^7*, Rachael F Grace, MD⁸, Shuoyan Ning^9*, Justin W Yan^10*, Amanda Pfeiffer^11*, Michele P Lambert, MD^12,13*, Karen Panckeri^14*, Allyson M Pishko, MD¹⁵, Kristine VanAarsen^16*, Ahmed Slim^17*, Kathryn M. Carrier^18*, Rebecca Geer^19*, Abinaya Arulselvan^20*, Matthew Basara^20*, Brenna Cannon^20*, Ellis Bloom, DO^21*, Sam J King^20*, Daya Gill^5*, Laura M. Venier^5*, Emily Xu^5*, Ishaq Siddiqui^22*, Bonnie Liu^5*, Taylah Buissereth, BS^23*, Timothy Mercier^24*, Emily M. Harris^24*, Enass H. Raffa^25,26*, Joel Livingston^27*, Dongyoung Kim^5*, Maryam Akbari-Moghaddam^5,28*, Gordon Guyatt, MD^29,30*, Dena Zeraatkar^31,32*, Lehana Thabane^31* and Donald Arnold, MD^2,33

¹Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University, Hamilton, ON, Canada
²Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada
³Michael G. DeGroote Centre for Transfusion Research, Department of Medicine, Hamilton, ON, Canada
⁴Yale School of Medicine, New Haven
⁵Michael G. DeGroote Centre for Transfusion Research, Department of Medicine, McMaster University, Hamilton, ON, Canada
⁶Department of Medicine and Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
⁷Hospital for Sick Children, Toronto, Canada
⁸Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA
⁹McMaster University, Hamilton, ON, CAN
¹⁰London Health Sciences Centre, Western University, London, Canada
¹¹Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹²Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
¹³Division of Hematology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
¹⁴Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia
¹⁵Department of Medicine, Division of Hematology-Oncology, University of Pennsylvania, Philadelphia, PA
¹⁶London Health Sciences Centre, London, ON, Canada
¹⁷St. Joseph's Healthcare London, London, ON, Canada
¹⁸Harvard Medical School, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, MA
¹⁹Department of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²⁰The Children's Hospital of Philadelphia, Division of Hematology, Philadelphia
²¹Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
²²Faculty of Health Sciences, McMaster University, Hamilton, Canada
²³Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
²⁴Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston
²⁵Department of Pediatrics, King Abdulaziz University, Jeddah, Saudi Arabia
²⁶Department of Oncology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
²⁷Pediatric Hematology/KidClot, Department of Paediatrics, Stollery Children’s Hospital and University of Alberta, Edmonton, Canada
²⁸Department of Computing and Software, McMaster University, Hamilton, ON, Canada
²⁹Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University, Hamilton, ON, CAN
³⁰Department of Medicine, McMaster University, Hamilton, Canada
³¹Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University, Hamilton, Canada
³²Department of Anesthesia, McMaster University, Hamilton, Canada
³³Department of Medicine, McMaster University, Hamilton, ON, Canada

Alexandra Schifferli, MD^1*, Nathalie Aladjidi, MD^2,3*, Guillaume Moulis^4,5*, Marlies Gisin^6*, Guy Leverger, MD, PhD^7*, Sebastien Heritier, MD^8*, Thierry Leblanc^9*, Helder Fernandes^10*, Mony Fahd, MD MSc^11* and Thomas Kuehne, MD¹²

¹Oncology/Hematology, University Children's Hospital Basel, 4031 Basel, Switzerland
²Centre de Référence National des Cytopénies Autoimmunes de l’Enfant (CEREVANCE), Bordeaux University Hospital, Bordeaux, France
³Pellegrin Hospital, CIC1401, INSERM CICP, Bordeaux University Hospital, Pediatric Hemato-Immunology, Bordeaux, AL, FRA
⁴Department of Internal Medicine, Toulouse University Hospital, Toulouse, France
⁵Clinical Investigation Center 1436, Team PEPSS Pharmacologie en Population, cohorteS, biobanqueS, Toulouse University Hospital, Toulouse, France
⁶Departement of Hematology/Oncology, University Children's Hospital Basel, Basel, Switzerland
⁷Pediatric Hematology Oncology Immunology Department, Hôpital Trousseau, Paris, France
⁸Pediatric Hematology Oncology Immunology Department, Armand-Trousseau University Hospital, Paris, FRA
⁹Hopital Universitaire Robert-Debré, Paris, France
¹⁰Centre de Référence National des Cytopénies Autoimmunes de l’Enfant (CEREVANCE),, Bordeaux University Hospital, Bordeaux, France
¹¹Pediatric hematology and immunology department, Robert-Debré Hospital, GHU APHP Nord Université Paris-Cité, Paris, France
¹²Department of Hematology/Oncology, University Children's Hospital UKBB, Basel, CHE

Yoann Zadro, MD^1,2*, Margaux Lafaurie^1,3*, Maryse Lapeyre-Mestre^1,3* and Guillaume Moulis^1,2*

¹Clinical Investigation Center 1436, Toulouse University Hospital, Toulouse, France
²Department of Internal Medicine, Toulouse University Hospital, Toulouse, France
³Department of Clinical Pharmacology, Toulouse University Hospital, Toulouse, France

Michelle MH Tan, MSc^1*, Amna Malik, PhD^2*, Jiawen Wang, BSc^2*, Clara Lo, MD^3*, Alice Hart^4*, Nehal Joshi^4*, Stuart Adams^5*, Patrick Zhang, PhD^6*, Katayoun Rezvani, MD, PhD⁶, Bing Zhang, MD^7* and Nichola Cooper, MD^2,4*

¹Imperial College London, Centre for Haematology, Department of Immunology and Inflammation, London, ENG, United Kingdom
²Imperial College London, Centre for Haematology, Department of Immunology and Inflammation, London, United Kingdom
³Stanford University, Palo Alto, CA
⁴Imperial College Healthcare NHS Trust, London, United Kingdom
⁵Great Ormond Street Hospital for Children, London, United Kingdom
⁶Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Stanford Hospital & Clinics, Palo Alto, CA

Mariia Kumskova, MD¹, Gagan D. Flora, PhD¹, Manasa K. Nayak, PhD¹, Ivan Budnik, MD, PhD^1*, Madankumar Ghatge, PhD^1*, Neelam Chauhan, PhD^1*, Aditi Jain^1*, Janice Staber, MD², Steven R. Lentz, MD, PhD¹ and Anil K. Chauhan, PhD¹

¹University of Iowa, Iowa City, IA
²Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA

Johan Rebetz, PhD^1*, Genevieve Marcoux, PhD^1*, Marc Bigaud, PhD^2*, Elissa Furutani, MD^3*, Tatjana Uffelmann, MSc^2*, Sabina Pfister, PhD^2*, Barbara Nüsslein-Hildesheim, PhD^2*, Pascal Edrich, PhD^2*, Isabelle Isnardi, PhD^2*, Christoph Burkhart, PhD^2* and John W Semple, PhD^1,4

¹Division of Hematology and Transfusion Medicine, Lund University, Lund, Sweden
²Novartis Pharma AG, Basel, Switzerland
³Novartis Biomedical Research, Cambridge, MA
⁴Clinical Immunology and Transfusion Medicine, Office of Medical Services, Lund, Sweden