Abena Appiah-Kubi, MD, MPH¹, Seethal A Jacob, MD, MS^2,3, Matthew M. Heeney, MD⁴, Connie M. Piccone, MD⁵, Omar Niss, MD⁶, Charles T. Quinn, MD, MS⁷, Stephanie A. Fritch Lilla, MD⁸, Maa-Ohui Quarmyne, MD, MS⁹, Angeli Rampersad, MD^10*, Allison Remiker, MD^11*, Amy Tang, MD¹², Min Dong, PhD^13*, Kathryn McElhinney, BS^14*, Joshua R. Tanzer, PhD^15* and Patrick T. McGann, MD, PhD^16,17

¹Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY
²Department of Pediatrics, Division of Children’s Health Services Research, Indiana University School of Medicine, Indianapolis, IN
³Department of Pediatrics, Division of Pediatric Hematology, Oncology, and Stem Cell Transplant, Riley Hospital For Children, Indianapolis, IN
⁴Dana–Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
⁵Carle Foundation Hospital, Urbana, IL
⁶Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁷Division of Hematology, Cincinnati Children's Hospital Med. Ctr., Cincinnati, OH
⁸Children's Minnesota, Minneapolis, MN
⁹Center of Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, AZ
¹⁰Indiana Hemophilia and Thrombosis Center, Indianapolis, IN
¹¹Medical College of Wisconsin, Division of Pediatric Hematology/Oncology/Bone Marrow Transplant, Pewaukee, WI
¹²Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA
¹³Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹⁴Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹⁵Lifespan Biostatistics, Epidemiology, and Research Design, Providence, RI
¹⁶Brown University Health Sickle Cell Center, Providence, RI
¹⁷The Warren Alpert Medical School of Brown University, Providence, RI

Josu de la Fuente, PhD FRCP^1,2, Jacques-Emanuel Galimard^3*, Arnaud Dalissier, BSc^4*, Mohsen Al Zahrani^5*, Ali Alahmari, MD^6*, Fahad Almohareb⁶, Jean-Hugues Dalle, MD, PHD⁷, Nathalie Dhédin, MD^8*, Hakan Ozdogu, MD^9*, Mohamed Salaheldin Bayoumy, MD^10*, Marco Zecca, MD^11*, Cristina Belendez, MD^12*, Javid Gaziev, MD, PhD^13*, Arjan C. Lankester, MD PhD^14*, Philippe Lewalle Sr., MD^15*, Gaurav Kharya, DCH, DNB, FIAP^16*, Sarah Lawson^17*, Bénédicte Neven^18*, Sandrine Bremathas, RN^19* and Emanuele Angelucci, MD²⁰

¹Department of Paediatrics, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
²Division of Immunology and Inflammation, Imperial College London, London, United Kingdom
³EBMT Paris Study Office, Paris, FRA
⁴EBMT Paris Study Unit, Saint Antoine Hospital, INSERM UMR-S 938, Sorbonne University, Paris, France
⁵Oncology department, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University of Health Sciences, Saudi society of bone marrow transplant, Riyadh, Saudi Arabia
⁶Department of Hematology, Stem Cell Transplantation, and Cellular Therapy, Cancer Center of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
⁷Department of Pediatric Hematology and Immunology, Robert-Debré Academic Hospital ,, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
⁸Service d'Hématologie Adolescents et Jeunes Adultes, Hôpital Saint-Louis, PARIS, France
⁹Baskent University Hospital, Adana, TUR
¹⁰King Faisal Specialist Hospital & Research Center, Jeddah, SAU
¹¹Pediatric Hematology-Oncology,, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
¹²Pediatric Hemato-Oncology, Hospital Gregorio Marañón, IiSGregorio Marañón, CIBERER-ISCIII, ERN-EuroBloodNet, Faculty of Medicine, Universidad Complutense, Madrid, Spain., Madrid, Spain
¹³Mediterranean Institute of Hematology, Rome, ITA
¹⁴Division of Stem cell Transplantation, Department of Pediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, Netherlands
¹⁵Hôpital Universitaire de Bruxelles (HUB), Institut Jules Bordet, Hematology Department, Brussels, BEL
¹⁶Indraprastha Apollo Hospital, Delhi, India
¹⁷Birmingham Children`s Hospital, Birmingham, United Kingdom
¹⁸Unité d'Immuno-Hématologie et Rhumatologie Pédiatrique, Assistance Publique-Hôpitaux de Paris, Paris, France
¹⁹IMPERIAL COLLEGE HEALTHCARE NHS TRUST, London, United Kingdom
²⁰Hematology and Cellular Therapy, IRCCS Ospedale Policlinico San Martino, Genova, ITA

Haiou Li^1*, Vandana Sachdev, MD^2*, Xin Tian, PhD^3*, My-Le Nguyen, MD^2*, Matthew Hsieh, MD⁴, Courtney D. Fitzhugh, MD⁴, Emily Limerick, MD⁴, Wynona Coles^4*, Nancy Asomaning, MS^5*, Anna Conrey, NP^5*, Colin O. Wu, PhD^6* and Swee Lay Thein, MBBS, DSc, FRCP, FRCPath, MRCP, MRCPath⁵

¹Sickle Cell Branch, National Heart, Lung, and Blood Institute, NIH, Arlington, VA
²Echocardiography laboratory, National Heart, Lung and Blood Institutes, NIH, Bethesda, MD
³Office of Biostatistics Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD
⁴Cellular and Molecular Therapeutics Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD
⁵Sickle Cell Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD
⁶Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

Titilope A Adeyemo, MBBS, MSc, FMCPath^1*, Nelly Kiriza, MD, MPH^2,3*, Feyisayo T. Oluwole, RN^1*, Mark Jelinek, MS^4*, Jude Jonassaint, RN^2*, Olubusola Oluwole, MD, MS^2,3, Christine Saber, MD^2,3*, Brian J Philips, PhD^3*, Olusegun-Joseph D Akinsanya, FMCP^1*, Vincent O Osunkalu, FMCPath^1*, Laura M. DeCastro, MD, MHSc^2,3, Enrico M Novelli, MD, MS^2,3 and Julia Z Xu, MD, MS^2,3

¹College of Medicine University of Lagos (CMUL), Lagos, Nigeria
²Division of Classical Hematology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA
³Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA
⁴Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA

Sophia Delicou^1*, Fuad El Rassi^2*, Biree Andemariam, MD³, Miguel R. Abboud, MD⁴, Julie Kanter, MD⁵, Marilyn J. Telen, MD⁶, Jessie Githanga^7*, Adlette Inati, MD⁸, Ibrahim Idris⁹, Sunil Navani^10*, Eric Wu^11* and Andrew Eisenberger¹²

¹Hippokrateio General Hospital, Athens, Greece
²Emory University School of Medicine, Atlanta, GA
³University of Connecticut Health, Farmington, CT
⁴American University of Beirut, Beirut, Lebanon
⁵University of Alabama at Birmingham, Birmingham, AL
⁶Duke University Medical Center, Durham, NC
⁷University of Nairobi, Nairobi, Kenya
⁸Lebanese American University Gilbert and Rose-Marie Chagoury School of Medicine, Byblos and NINI Hospital, Tripoli, Lebanon
⁹Aminu Kano Teaching Hospital/Bayero University, Kano, Nigeria
¹⁰Novo Nordisk Ltd, Oxford, United Kingdom
¹¹Novo Nordisk Inc., Lexington, KY
¹²Columbia University Irving Medical Center, New York, NY

Matthew M. Heeney, MD¹, David C Rees², Slimane Allali^3*, Isaac Odame, MBBCh⁴, Rodolfo D Cançado^5*, Adlette Inati, MD⁶, Elena Cela, MD, PhD^7*, Deborah Keefe^8*, Evgeniya Reshetnyak^8*, Velusamy Shanmuganathan Muthusamy^9*, Lidiya Bebrevska^10*, Michele L Nassin⁸ and Julie Kanter, MD¹¹

¹Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, MA
²Department of Paediatric Haematology, King's College London, London, United Kingdom
³Department of Pediatrics and Sickle Cell Center APHP, Centre-Université Paris Cité, Necker Hospital for Sick Children, Laboratory of Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, INSERM U1163, Institut Imagine, Paris, France
⁴The Hospital for Sick Children (SickKids) and the University of Toronto, Toronto, ON, Canada
⁵Department of Oncology and Hematology, Hospital Samaritano de Sao Paulo, São Paulo, Brazil
⁶Lebanese American University Gilbert and Rose-Marie Chagoury School of Medicine, Byblos and NINI Hospital, Tripoli, Lebanon
⁷Pediatric Hematology and Oncology, Hospital Gregorio Marañón. Universidad Complutense de Madrid, Madrid, Spain
⁸Novartis Pharmaceuticals Corporation, East Hanover, NJ
⁹Novartis Healthcare Pvt. Ltd., Hyderabad, India
¹⁰Novartis Pharma AG, Basel, Switzerland
¹¹University of Alabama at Birmingham, Birmingham, AL