Scientific Program
Bleeding and Clotting, Fundamental Science, Research, Diseases
Room 7
(San Diego Convention Center)
Description:
Blood transfusion requires the donation of blood products from a diverse array of individuals with unique genetics and environmental inputs. This results in the quality and overall behavior of the blood products being less standardized and predictable, with direct consequences on transfused recipients. This session will focus on how recently recognized unique genetic and environmental backgrounds of both the blood donor and the transfusion recipient influence the outcomes of patients. Newly applied metabolic tools reveal metabolic variability in donors and recipients, shedding light on fundamental aspects of these differential responses of transfusion in patients, which could guide future strategies for more personalized and effective blood transfusions.
Chair:
Cassandra Dorothy Josephson, MD, ARRAY(0xe4f847c)
Disclosures:
Josephson: Westat: Consultancy, Honoraria; Medtronics: Research Funding; Immucor: Honoraria.
Blood transfusion requires the donation of blood products from a diverse array of individuals with unique genetics and environmental inputs. This results in the quality and overall behavior of the blood products being less standardized and predictable, with direct consequences on transfused recipients. This session will focus on how recently recognized unique genetic and environmental backgrounds of both the blood donor and the transfusion recipient influence the outcomes of patients. Newly applied metabolic tools reveal metabolic variability in donors and recipients, shedding light on fundamental aspects of these differential responses of transfusion in patients, which could guide future strategies for more personalized and effective blood transfusions.
Angelo D'Alessandro, PhD
Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO
Moritz Stolla, MD
Bloodworks and University of Washington, Pathology and Laboratory Medicine, Seattle, WA; Bloodworks Northwest Research Institute, Seattle, WA; Department of Medicine, Division of Hematology, University of Washington, Seattle, WA
Cheryl Lobo, PhD
Laboratory of Blood-Borne Parasites, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY
denotes an abstract that is clinically relevant.
denotes that this is a ticketed session.