John James^1*, Biree Andemariam, MD², Johnny Mahlangu, MBBCh, MMed³, Raffaella Colombatti, MD⁴, John Waller^5*, Samar Al-Behaisi^5*, Adam Wufsus⁶, Gareth Morrell^7* and Cassandra Trimnell, BA^8*

¹Sickle Cell Society, London, United Kingdom
²University of Connecticut Health, Farmington, CT
³University of the Witwatersrand and National Health Laboratory Service, Johannesburg, South Africa
⁴University of Padova, PADOVA, ITALY, Italy
⁵Novo Nordisk Health Care AG, Zurich, Switzerland
⁶Novo Nordisk Inc., Plainsboro, NJ
⁷Madano, London, United Kingdom
⁸Sickle Cell 101, San Francisco, CA

Biree Andemariam, MD¹, Henny H. Billett, MD², William B Ershler, MD³, Shayla Bergmann, MD⁴, Vishwas S. Sakhalkar^5*, Alicia Chang, MD⁶, Payal Desai, MD⁷, Nirmish Shah, MD^8*, Sharon Pennington, MD⁹, Robin E. Miller, MD¹⁰, Laura M. Decastro, MD¹¹, Michelle Xu^12*, Brooke Hayward^12*, Ching-Ray Yu^12* and Darla K. Liles, MD¹³

¹University of Connecticut Health, Farmington, CT
²Albert Einstein College of Medicine, Bronx, NY
³Inova Schar Cancer Institute, Fairfax, VA
⁴Medical University of South Carolina, Charleston, SC
⁵Augusta University Health, Augusta, GA
⁶Pediatric Hematology/Oncology, Dell Children’s Medical Center, Austin, TX
⁷Levine Cancer, Atrium Health, Charlotte, NC
⁸Duke University School of Medicine, Durham, NC
⁹Mississippi Center For Advanced Medicine, Madison, MS
¹⁰Nemours Center for Cancer and Blood Disorders, Nemours Children’s Health, Wilmington, DE
¹¹UPMC Hillman Cancer Center, Pittsburgh, PA
¹²Pfizer Inc, New York, NY
¹³East Carolina University Health, Brody School of Medicine, Greenville, NC

Anoosha Habibi, MD¹, Maryse Etienne-Julan, MD^2*, Emmanuelle Bernit, MD^3*, Maria Dimopoulou, MD^4*, Pagona Flevari, MD, PhD^4*, Ersi Voskaridou, MD^5*, Narcisse Elenga, MD, PhD^6*, Estelle Jean-Mignard, MD^7*, Giovanna Cannas, MD^8* and Pablo Bartolucci, MD, PhD^9*

¹Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Henri-Mondor, AP-HP, Université Paris-Est, Créteil, France
²CHU De Pointe-à-Pitre, Pointe-à-Pitre, Guadeloupe
³CHU Pointe-à-Pitre, Pointe à Pitre, Guadeloupe
⁴Laiko General Hospital, Athens, Greece
⁵Thalassaemia Centre, Laikon General Hospital, Athens, Greece
⁶CH Andrée Rosemon, Cayenne, French Guiana
⁷Hôpital de la Timone, Marseille, France
⁸Hopital Edouard Herriot, Lyon, France
⁹Service de Médecine Interne, CHU Henri Mondor, Créteil, France

Sherif M. Badawy, MD, MBA, MS^1,2, Jan Palmblad, MD, PhD³, Fernando Tricta, MD⁴, Noemi Toiber Temin, MA^5*, Caroline Fradette, PhD⁴, Leo Lin, MSc^5*, Anna Rozova, MSc, MD^4* and Sujit Sheth, MD⁶

¹Ann & Robert Lurie Children's Hospital, Chicago, IL
²Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL
³Karolinska Institutet, Stockholm, SWE
⁴Hematology/Immunology Program, Chiesi Canada Corporation, Toronto, ON, CAN
⁵Hematology/Immunology Program, Chiesi Canada Corporation, Toronto, ON, Canada
⁶Division of Hematology and Oncology, Department of Pediatrics, Weill Cornell Medicine, New York, NY

Lana Mucalo, MD^1*, Shuang Jia^1*, Ashima Singh, PhD², Mark Roethle^1*, Janelle Highland, MA^1*, Dawn Retherford^1*, Jessica J. Rico^1*, Nicole Steiner^1*, Martin Hessner, PhD^1* and Amanda M. Brandow, DO, MS³

¹Medical College of Wisconsin, Milwaukee, WI
²Department of Pediatrics, Division of Hematology and Oncology, Medical College of Wisconsin, Pewaukee, WI
³Department of Pediatrics, Section of Hematology/Oncology/Bone Marrow Transplantation, Medical College of Wisconsin, Milwaukee, WI

Thomas d'Humières, MD^1*, Zineb Sadraoui^2*, Laurent Savale, MD, PhD^3*, Laurent Boyer, MD, PhD^4*, Gonzalo De Luna, MD^5*, Anoosha Habibi, MD⁶, Laurent Messonier^7*, David Calvet, MD, PhD^8*, Nicolas Lellouche, MD, PhD^9*, Geneviève Derumeaux, MD, PhD^10* and Pablo Bartolucci, MD, PhD^5*

¹Physiology Department, FHU SENEC, INSERM IMRB U955, Henri-Mondor University Hospital- UPEC, AP-HP, Creteil, France
²Physiology, Henri Mondor teaching hospital, Créteil, France
³Kremblin Bicêtre teaching hospital, Le Kremlin Bicêtre, FRA
⁴CHU Henri Mondor, Créteil, France
⁵Sickle Cell Referral Center, Henri-Mondor University Hospital- UPEC, AP-HP, Creteil, France
⁶Sickle Cell Referral Center, Henri-Mondor University Hospital- UPEC, AP-HP, Creteil Cedex, FRA
⁷Inter-university Laboratory of Human Movement Sciences EA 7424, Université Savoie Mont Blanc,, Chambéry, France
⁸Centre Hospitalier Sainte-Anne, Paris, France
⁹Cardiology Department, Henri Mondor Hospital, Assistance Publique HôPitau, CréTeil, FRA
¹⁰CHU Henri Mondor, FHU SENEC, Créteil, France

Parima Saxena, MD, MSc¹, Riddhi Chauhan, DO^1*, Prashil Dave, MBBS^1*, Dedipya Bhamidipati, MD^1*, Edwin Chiu, MD^2* and John Muthu, MBBS^3*

¹Internal Medicine, SUNY Downstate, Brooklyn, NY
²Hematology and Oncology, New York City Health and Hospitals, Kings County, Brooklyn, NY
³Sickle Cell Division, New York City Health and Hospitals, Kings County, Brooklyn, NY

Upama Giri¹, Alan Sheinei, MD, PhD^2*, Chad Zik, MD^2*, Rania Fusisi, BSN^2* and William B Ershler, MD²

¹Inova Schar Cancer Institute, Vienna, CA
²Inova Adult Sickle Cell Center, Inova Schar Cancer Institute, Fairfax, VA

Olufunke Y. Martin, MD^1,2, Bindu Parachalil Gopalan, PhD^2*, Jian Sun, PhD^3*, Ashima Singh, PhD⁴, Neal Jeffries, PhD^5* and Arun S. Shet, MD, PhD²

¹Center for Cancer and Blood Disorders, Children's National Hospital, Woodbury, MN
²Sickle Thrombosis and Vascular Biology Lab, Sickle Cell Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD
³Integrated Data Sciences Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD
⁴Department of Pediatrics, Division of Hematology and Oncology, Medical College of Wisconsin, Pewaukee, WI
⁵Office of Biostatistics Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD

Madison Canning, MD^1*, Yi Liu, MS^2*, Shruti Gupta, MD^3*, Morgan L. McLemore, MD⁴ and Fuad El Rassi, MD^5*

¹J. Willis Hurst Internal Medicine Residency Program, Emory University School of Medicine, ATLANTA, GA
²Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA
³J. Willis Hurst Internal Medicine Residency Program, Emory University School of Medicine, Atlanta, GA
⁴Georgia Comprehensive Sickle Cell Center at Grady Health System, Atlanta, GA
⁵Emory University School of Medicine and Georgia Comprehensive Sickle Cell Center at Grady Health System, Atlanta, GA

Kit Neikirk^1*, Christopher Gamper², Alicia Cannon, PhD^3*, Aliyah Allick, BS^4*, Wilfreda Lindsey, MD, MS^4*, Bridget Gibbons^4* and Eboni Lance, MD, PhD⁵

¹Kennedy Krieger Institute, Kurtistown, HI
²Johns Hopkins University School of Medicine, Baltimore, MD
³Neuropsychology, Kennedy Krieger Institute, Baltimore, MD
⁴Kennedy Krieger Institute, Baltimore, MD
⁵Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD

Marwah Farooqui, DO¹, Elisa Martinez, MD candidate^2*, Kaitlin Sung, MD candidate^3*, Marianna Vakaki, MD candidate^2*, Kayla Gross, MD candidate^2*, Xu Zhang, PhD^4*, Victor R. Gordeuk, MD⁵ and Gelila Goba, MD, MPH^6*

¹Hematology Oncology, University of Illinois, Burr Ridge, IL
²College of Medicine, University of Illinois, Chicago
³UIC College of Medicine, Chicago, IL
⁴UIC, Chicago, IL
⁵Department of Medicine, University of Illinois Chicago, Chicago, IL
⁶Department of Obstetrics & Gynecology, University of Illinois, Chicago

Caleb T Spencer, MD^1*, Jennifer Kim^2*, Swamroop V Nandwani^2*, Abdulmajeed Alharbi, MD^1*, Alexander J. Didier², Daniel J Craig, MD, PhD^1* and Mohammad Khan, DO³

¹Department of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH
²University of Toledo College of Medicine and Life Sciences, Toledo, OH
³Division of Hematology and Oncology, Department of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH

Gabriela Ramirez Cuebas, MD¹, Shehu Umar Abdullahi, MD^2*, Safiya Gambo, MBBS^3*, Hassan Adam Murtala, MBBS^3*, Halima Kabir, MBBS^2*, Khadija A. Shamsu, MBBS^2*, Garba Gwarzo, MBBS^2*, Sari A Acra, MD, MPH^4*, Virginia Stallings, MD^5*, Mark Rodeghier, PhD^6*, Michael R. DeBaun, MD, MPH^7,8 and Lauren J Klein, MD^4,7

¹Department of Pediatrics, University of Puerto Rico School of Medicine, San Juan, PR
²Department of Pediatrics, Bayero University/Aminu Kano Teaching Hospital, Kano, Nigeria
³Department of Pediatrics, Murtala Mohammad Specialist Hospital, Kano, Nigeria
⁴Department of Pediatrics, D. Brent Polk Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN
⁵Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA
⁶Rodeghier Consultants, Chicago, IL
⁷Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, TN
⁸Vanderbilt University School of Medicine, Nashville, TN

Amanda Walker, MD^1*, Surabhi Batra, MD, MBBS^2*, Kristin Wong, MD^1* and Philip Kasirye, MD^3*

¹Rutgers-New Jersey Medical School, Newark, NJ
²Children’s Hospital of New Jersey, Newark Beth Israel Medical Center, Newark, NJ
³Mulago National Referral Hospital, Kampala, Uganda

Sarah Sewaralthahab, MBBS, MPH¹, Lujain A Alsubki, MBBS^2*, Maram S Alhrabi^3* and Abdulrahman S. Alsultan, MBBS⁴

¹Internal Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
²Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
³Oncology Center, King Saud University Medical City, Riyadh, Saudi Arabia
⁴Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia

Andrew Ross Wickman O'Brien, MD¹ and Robert Brinton Fujiki, PhD CCC-SLP^2*

¹Division of Hematology/Oncology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN
²Department of Surgery, University of Wisconsin-Madison, Madison, WI

Myrthe J. van Dijk^1,2*, Minke A.E. Rab^2,3*, Brigitte A. van Oirschot^2*, Jennifer Bos^2*, Cleo Derichs^1*, Anita W. Rijneveld, M.D.³, Marjon H. Cnossen^4*, Erfan Nur, MD, PhD^5,6, Bart J. Biemond^7*, Marije Bartels^1*, Judith J.M. Jans^8*, Wouter W. van Solinge^2*, Roger E.G. Schutgens, MD, PhD, MSc^1*, Richard van Wijk^9* and Eduard J. Van Beers, MD, PhD^10,11,12*

¹Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands
²Central Diagnostic Laboratory - Research, University Medical Center Utrecht, Utrecht, Netherlands
³Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands
⁴Department of Pediatric Hematology, Erasmus MC Sophia Children's Hospital, Rotterdam, Netherlands
⁵Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam, Netherlands
⁶Department of Hematology, Amsterdam University Medical Centers, Amsterdam, Netherlands
⁷Department of Hematology, Amsterdam University Medical Center, Amsterdam, Netherlands
⁸Section Metabolic Diagnostics, Department of Genetics, University Medical Center Utrecht, Utrecht, Netherlands
⁹Central Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands
¹⁰Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Centre Utrecht, Utrecht, Netherlands
¹¹Benign Hematology Center, Van Creveldkliniek, University Medical Center Utrecht, University of Utrecht, Utrecht, Netherlands
¹²Benign Hematology Center, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands

Wasil Jastaniah, MBBS, FRCPC^1*, Regina Hartfield^2*, John James^3*, Biba Tinga^4*, Elvie Ingoli^5*, Mariane de Montalembert, MD, PhD⁶, Fernando F. Costa^7*, Alan Randall Anderson, MD⁸, Joachim B. Kunz, MD^9*, Isaac Odame, MD¹⁰, Belinda Lartey^11* and Baba P.D. Inusa^12*

¹King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia
²Sickle Cell Disease Association of America, Inc, Hanover, MD
³Sickle Cell Society, London, United Kingdom
⁴Sickle Cell Disease Association of Canada, Toronto, Canada
⁵IST e.V., German Sickle Cell Disease and Thalassemia Association, Eschweiler, Germany
⁶Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Paris, France
⁷Hematology and Hemotherapy Centre, School of Medicine, University of Campinas - UNICAMP, Campinas, Brazil
⁸PRISMA Health Comprehensive Sickle Cell Disease Program, University of South Carolina School of Medicine, Greenville, SC
⁹Hopp Children’s Cancer Center Heidelberg (KiTZ), University of Heidelberg, Heidelberg, Germany
¹⁰The Hospital For Sick Children, University of Toronto, Toronto, Canada
¹¹Ipsos Healthcare, London, United Kingdom
¹²Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom

Neha Bhasin, MD¹, Quentin Eichbaum, MD, PhD, MPH, MFA, MMHC, JD, MMed, FCAP, FASCP^2*, Dana Marie LeBlanc, MD, MS³, Sean Yates, MD⁴, An Pham, MD, MS⁵, Deva Sharma, MD⁶, Elliott P. Vichinsky, MD¹, Erin Rosales, CRC^7* and Ravi Sarode, MD⁴

¹Department of Pediatrics, Division of Hematology, University of California San Francisco Benioff Children's Hospital, Oakland, CA
²Transfusion Medicine, Vanderbilt University School of Medicine, Nashville, TN
³Louisiana State University Health Science Center, New Orleans, LA
⁴Department of Transfusion Medicine, UT Southwestern Medical Center, Dallas, TX
⁵Department of Pediatrics, UT Southwestern University, Dallas, TX
⁶Department of Medicine, Division of Hematology, Vanderbilt University School of Medicine, Nashville, TN
⁷University of California San Francisco Benioff Children's Hospital, Oakland, CA

Akshay Sharma, MBBS¹, Anthony Merlocco, MD MSt FSCMR^2,3,4*, Cara Morin, MD, PhD^5*, Subodh Selukar, PhD^6*, Yu Bi, MS^6*, Chris Goode, BS^4*, Parul Rai, MBBS⁷, Brandon M Triplett, MD^8*, Jeffrey Towbin, MD, MS^2*, Jane S Hankins, MD, MS⁹ and Jason N Johnson, MD, MHS^2,3,4*

¹St. Jude Children's Research Hospital, Memphis, TN
²Division of Pediatric Cardiology, The University of Tennessee Health Science Center, Memphis, TN
³Division of Pediatric Radiology, The University of Tennessee Health Science Center, Memphis, TN
⁴Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, TN
⁵Department of Pediatric Radiology, Cincinnati Children’s Hospital, Cincinnati, OH
⁶Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, TN
⁷Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN
⁸Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN
⁹Departments of Hematology and Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, TN

Chih-Chiang Chang¹, Matthew A. Scoggins^1*, Ping Zou^1*, Sydney Somogyi^2*, Soniya Pinto^1*, Kathleen Helton^1*, Jane S Hankins, MD, MS³, Brandon M Triplett, MD^4*, Akshay Sharma, MBBS⁵ and Ranganatha Sitaram^1*

¹Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN
²Department of Biology, East Tennessee State University, Johnson City, TN
³Departments of Hematology and Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, TN
⁴Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN
⁵St. Jude Children's Research Hospital, Memphis, TN

Edo Schaefer, MD¹, Morgan Anderson-Crannage, BSc^1*, Jessica Hochberg, MD^1*, Temima Kanarfogel^1*, Yiouli Panayiota Ktena, MD², John Herrick^1*, Emily Thatcher, PA^1*, Qiuhu Shi, PhD^1*, Bruno Hochberg^1*, Yaya Chu, PhD^1*, Sankaran Krishnan, MD, MPH, FAAP^1*, Erin Morris, RN, BSN^1*, Sandra Fabricatore, RN, MSN, CPNP^1*, John DuFresne, CRA^1*, Kenneth R. Cooke, MD² and Mitchell S. Cairo, MD³

¹New York Medical College, Valhalla, NY
²The Sidney Kimmel Comp. Cancer Center At Johns Hopkins, Baltimore, MD
³Department of Pediatrics, New York Medical College, Valhalla, NY

Sophia Horiuchi, BA^1*, Tomia Austin, DrPH^2*, Elliott P. Vichinsky, MD³ and Susan Paulukonis, MA, MPH^4*

¹Public Health Institute, Tracking California, Richmond, CA
²As One Foundation, Houston, TX
³Department of Pediatrics, Division of Hematology, University of California San Francisco Benioff Children's Hospital, Oakland, CA
⁴Public Health Institute, Tracking California, Oakland, CA

Galia Pollock, MD, BS, FRCPC^1,2, Anish Vora, MD^3,4*, Lillian McMahon, MD^2,5*, Jean-Antoine Ribeil, MD, PhD^1,2*, Amy E. Sobota, MD, MPH^3,6*, Charlene Sylvestre, NP^4,7*, Robyn T. Cohen, MD, MPH^6,8* and Elizabeth S. Klings, MD^6,9

¹Medicine, Boston Medical Center, Boston, MA
²Sickle Cell Disease Center of Excellence, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, Boston, MA
³Boston Medical Center, Boston, MA
⁴Department of Medicine, Boston University, Boston, MA
⁵Department of Medicine, Boston Medical Center, Boston, MA
⁶Sickle Cell Disease Center of Excellence, Boston University Chobanian and Avedisian School of Medicine, Boston, MA
⁷Sickle Cell Center of Excellence, Boston University Medical Center, Boston, MA
⁸Department of Pediatrics, Boston Medical Center, Boston, MA
⁹Pulmonary Center, Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA

Jose A. Mejias^1*, Alejandro R. Gonzalez-Barreto^2*, Mark Rodeghier, PhD^3* and Michael R. DeBaun, MD, MPH⁴

¹University of Puerto Rico, School of Medicine, Guaynabo, PR
²University of Puerto Rico, School of Medicine, San Juan, PR
³Rodeghier Consultants, Chicago, IL
⁴Vanderbilt University School of Medicine, Nashville, TN

Robert Molokie, MD¹, Santosh L. Saraf, MD^1,2, Lani Krauz^3*, Michael Pacini, PharmD^4*, David Chan, PharmD^4*, Alana Aziz-Bradley^4*, Rebeca Gansari^4*, Taif Hassan^5*, Philip Woost^6*, James Jacobberger^6*, Victor R. Gordeuk, MD⁷, Donald E. Lavelle, PhD⁸, Joseph DeSimone, PhD^5,9* and Yogenthiran Saunthararajah, MD¹⁰

¹Division of Hematology/Oncology, University of Illinois Chicago, Chicago, IL
²Department of Medicine, University of Illinois College of Medicine, Willowbrook, IL
³University of Illinois at Chicago, Chicago, IL
⁴Department of Medicine, University of Illinois Hospital and Health Sciences System, Chicago
⁵University of Illinois At Chicago, Chicago, IL
⁶Case Western Reserve University, Cleveland, OH
⁷Sickle Cell Center, University of Illinois at Chicago, Chicago, IL
⁸Department of Medicine, University of Illinois at Chicago, Chicago, IL
⁹University of Illinois at Chicago VA Chicago West Side Division, Chicago, IL
¹⁰Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Alan Randall Anderson, MD¹, John J Strouse, MD, PhD², Deepa Manwani, MD³, Amanda M. Brandow, DO, MS⁴, Elliott P. Vichinsky, MD⁵, Patrick Leavey, MD^6*, Joshua Field, MD⁷, Scott Hensley^8*, Nicole Mortier^9*, Sophie M. Lanzkron, MD¹⁰, Donna S. Neuberg, ScD¹¹ and Charles S. Abrams, MD¹²

¹PRISMA Health Comprehensive Sickle Cell Disease Program, University of South Carolina School of Medicine, Greenville, SC
²Department of Medicine, Division of Hematology, Duke University School of Medicine, Durham, NC
³Department of Pediatric Hematology-Oncology, Albert Einstein College of Medicine, Bronx, NY
⁴Department of Pediatrics, Section of Hematology/Oncology/Bone Marrow Transplantation, Medical College of Wisconsin and Children’s Research Institute of Children’s Wisconsin, Milwaukee, WI
⁵Children's Hospital Research Center Oakland, Oakland, CA
⁶Simmons Comprehensive Cancer Center, Children's Medical Center, Southwestern University, Dallas, TX
⁷Blood Center of Wisconsin, Medical College of Wisconsin, Versiti, Milwaukee, WI
⁸University of Pennsylvania, Philadelphia, PA
⁹ASH Research Collaborative, Washington, DC
¹⁰Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD
¹¹Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
¹²Department of Medicine, University of Pennsylvania, Philadelphia, PA

Praneeth Reddy Keesari, MD¹, Charan Thej Reddy Vegivinti, MD, MBBS², Ahmad Mustafa, MD^3*, Suzanne El-Sayegh, MD^3*, Hasnain Chaudhry^4*, Shweta Ravindra Deshpande, MBBS^5*, Ngowari Pokima^4*, Rajvi Gor, MD^6* and Ugochi Olivia Ogu, MD^7,8

¹Department of Internal Medicine, Staten Island University Hospital, Staten Island, NY
²Department of Medicine, Jacobi Medical Center / Albert Einstein College of Medicine, Bronx, NY
³Department of Internal Medicine, Northwell Health/Staten Island University Hospital, Staten Island, NY
⁴Staten Island University Hospital, Staten Island, NY
⁵Jacobi Medical Center/Albert Einstein College of Medicine, Bronx, NY
⁶Jacobi Medical Center / Albert Einstein College of Medicine, Bronx, NY
⁷Division of Hematology/Oncology, University of Tennessee Health Science Center, Memphis, TN
⁸Center for Sickle Cell Disease, University of Tennessee Health Sicence Center, Germantown, TN

Maureen Okam Achebe, MD, MPH¹, Hoda MA Hassab, MD^2*, Salam Al-Kindi^3*, Clark Brown, MD, PhD⁴, Paul Telfer, MD^5*, Bart J. Biemond⁶, Thokozeni Lipato^7*, Mark Davis^8*, Sarah Gray^8* and Victor R. Gordeuk, MD⁹

¹Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
²Alexandria University, Alexandria, Egypt
³Sultan Qaboos University, Muscat, Oman
⁴Pfizer Inc, Norcross, GA
⁵Royal London Hospital, Barts Health NHS Trust, London, United Kingdom
⁶Department of Hematology, Amsterdam University Medical Centers, location University of Amsterdam, Amsterdam, Netherlands
⁷Virginia Commonwealth University Medical Center, Richmond, VA
⁸Pfizer Inc., South San Francisco, CA
⁹Sickle Cell Center, University of Illinois at Chicago, Chicago, IL

Gianna G. Guzzardo, MD¹, Meera Chitlur, MD^2,3, Patrick C. Hines, MD, PhD⁴, Aliya U. Zaidi, PhD^5*, Rasa Borhan, BSc^5*, Kelsey Cinciarelli^2* and Alexander K Glaros, MD^2,3*

¹Division of Hematology/Oncology, Children’s Hospital of Michigan, Shelby Township, MI
²Division of Hematology/Oncology, Children’s Hospital of Michigan, Detroit, MI
³Central Michigan University College of Medicine, Mount Pleasant, MI
⁴Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI
⁵Functional Fluidics Inc., Detroit, MI

Najibah Galadanci, MBBS, PhD, MPH¹, Shannon Phillips, PhD, RN^2*, Alyssa M. Schlenz, PhD^3*, Nataliya Ivankova, PhD, MPH^4* and Julie Kanter, MD⁵

¹Department of Medicine/Hematology, University of Alabama at Birmingham, Birmingham, AL
²Medical University of South Carolina, Charleston, SC
³Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO
⁴University of Alabama at Birmingham, Birmingham, AL
⁵Division of Hematology and Oncology, University of Alabama, Birmingham, AL

Kathryn McElhinney, BS^1*, Luke R. Smart, MD^1,2, Thad Alan Howard, MS^1*, Alexandra Power-Hays, MD^1,2 and Russell E. Ware, MD, PhD^1,2

¹Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH

Ibrahim Musa Idris, MBBS, MPH¹, Aminu Abba Yusuf, MBBS, MSc^2*, Ismail Ismail, MBBS^1*, Awwal Musa Borodo, MD^3*, Kabiru Musangedu, MBF^4*, Tukur Aliyu, MBBS^1*, Datti Alfa, BNS^5*, Mustapha Shuaiabu Hikima, MBBS, FMCR^6*, Mohammad Suwaid, MBBS, FMCR^7*, Shehu Kana, MBBS, FWACP^8*, Sani Aji, MBBS, FWACS^9*, Aisha Kuliya_Gwarzo, MBBS, FMCPath^1*, Kabiru Bello Muhammad, BPharm^10*, Jamil Aliyu Galadanci, MSc^11*, Rukayya Alkassim, MSc^12*, Nafiu Hussaini, PhD^13*, Mark Rodeghier, PhD^14*, Arthur Burnett, MD, MBA^15,16* and Michael R. DeBaun, MD, MPH¹⁷

¹Haematology, Aminu Kano Teaching Hospital, Kano, Nigeria
²Haematology, Aminu Kano Teaching Hospital, Kano, NGA
³Haematology, Murtala Muhammad Specialist Hospital, Kano, NGA
⁴Research Coordination Unit, Aminu Kano Teaching Hospital, Kano, Nigeria
⁵Nursing, Aminu Kano Teaching Hospital, Kano, Nigeria
⁶Radiology, Muhammad Abdullahi Wase Teaching Hospital, Kano, NGA
⁷Radiology, Aminu Kano Teaching Hospital, Kano, NGA
⁸Medicine, Aminu Kano Teaching Hospital, Kano, NGA
⁹Aminu Kano Teaching Hospital, Kano, NGA
¹⁰Pharmacy, Aminu Kano Teaching Hospital, Kano, Nigeria
¹¹Computer Science, Bayero University Kano, Kano, NGA
¹²Statistics, Aliko Dangote University of Science and Technology, Wudil, Nigeria
¹³Mathematical Sciences, Bayero University Kano, Kano, Nigeria
¹⁴Rodeghier Consultants, Chicago, IL
¹⁵Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD
¹⁶Johns Hopkins University, Baltimore, MD
¹⁷Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease, Vanderbilt University Medical Center, Nashville, TN

Julie Kanter, MD¹, Sarah Mennito, MD, MSCR^2*, Santosh M Nair, MD³, Deepa Manwani, MD⁴, Abdullah Kutlar, MD^5*, Nirmish Shah, MD⁶, Deborah Keefe, MD, MPH^7*, Hariprasad Madhamshetty, MD (Ay)^8*, Evgeniya Reshetnyak, PhD^7*, Anisha E Mendonza, PhD^9* and Darla K. Liles, MD¹⁰

¹Division of Hematology and Oncology, University of Alabama, Birmingham, AL
²Medical University of South Carolina, Charleston, SC
³Mid Florida Hematology and Oncology Center, Orange City, FL
⁴Department of Pediatric Hematology-Oncology, Albert Einstein College of Medicine, Bronx, NY
⁵Department of Medicine, Medical College of Georgia, Augusta, GA
⁶Division of Hematology–Duke Sickle Cell Comprehensive Care Unit, Duke University Medical Center, Durham, NC
⁷Novartis Pharmaceuticals Corporation, East Hanover, NJ
⁸Novartis Healthcare Private Limited, Hyderabad, India
⁹Novartis Institutes for BioMedical Research, Cambridge, MA
¹⁰Division of Hematology–Oncology, Department of Internal Medicine, East Carolina University Brody School of Medicine, Greenville, NC