Kehan Ren^1,2, Zongjun Xia^3*, Ermin Li, Ph.D.^1*, Xu Han, PhD^1* and Peng Ji, MD, PhD¹

¹Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL
²Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
³Northwestern University, Chicago, IL

Karolina Dziewulska-Cronk^1*, Ariel M Hay^2*, Angelo D'Alessandro, PhD³, Julie A Reisz, PhD^3*, Jordan Garrett^1*, Paul Buehler, PharmD, PhD^4*, Joseph Kao^5* and James C Zimring, MD, PhD^1*

¹University of Virginia School of Medicine, Charlottesville, VA
²University of Virginia, Charlottesville, VA
³Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO
⁴Center for Blood Oxygen Transport and Hemostasis, University of Maryland, Baltimore, MD
⁵University of Maryland, Baltimore

Evrim Goksel^1*, Selahattin Can Ozcan^2*, Alisan Kayabolen^3* and Ozlem Yalcin^4*

¹Graduate School of Health Science, Koç University, Istanbul, Turkey
²Koç University Research Center for Tranlational Medicine, Koç University, Istanbul, Turkey
³Massachusetts Institute of Technology, Boston, MA
⁴School of Medicine, Koç University, Istanbul, Turkey

Barbara Eleni Rosato, PhD^1*, Vanessa D’Onofrio^1*, Antonella Nostroso^1*, Roberta Marra, PhD^1*, Federica Maria Esposito^1*, Maddalena Raia^2*, Giuseppe D’Alterio^3*, Mario Capasso, PhD^1*, Lucia De Franceschi, MD⁴, Achille Iolascon, MD, PhD^5*, Roberta Russo, PhD^6* and Immacolata Andolfo, PhD^7*

¹University of Naples Federico II, Ceinge biotecnologie avanzate, Napoli, Italy
²Ceinge biotecnologie avanzate, Napoli, Italy
³European School of Molecular Medicine, Università Degli Studi di Milano, Italy., Milan, Italy
⁴Dept of Medicine, Policlinico GB Rossi, Policlinico GB Rossi, Univ. of Vero, Verona, Italy
⁵University of Naples Federico II, Ceinge biotecnologie avanzate, Naples, ITA
⁶University of Naples "Federico II", Naples, Italy
⁷University of Naples Federico II, Ceinge biotecnologie avanzate, Naples, Italy

Claire Drysdale, BSc^1,2, Greggory Myers, B.S.², Lei Yu^2*, Ann Friedman, B.S.^3*, Claire Kerpet, B.S.^3*, Ginette Balbin-Cuesta, MD, PhD^1,4, Zesen Lin, BS⁵, Ayse Bilge Ozel, M.S., Ph.D.^6*, James Engel, Ph.D.² and Rami Khoriaty, M.D.^2,3,7,8

¹Medical Scientist Training Program, University of Michigan Medical School, Ann Arbor, MI
²Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI
³Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI
⁴Cellular and Molecular Biology Program, University of Michigan Medical School, Northville, MI
⁵Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI
⁶Department of Human Genetics, University of Michigan, Ann Arbor, MI
⁷Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, MI
⁸University of Michigan Rogel Cancer Center, Ann Arbor, MI

Bin Hu^1*, Han Gong^1*, Chaoying Yang^1*, Ling Nie, PhD^2*, Ji Zhang, PhD^3*, Long Liang, PhD^1*, Mohandas Narla, DSc⁴, Yue Sheng, PhD⁵ and Jing Liu, PhD^1*

¹Department of Hematology, The Second Xiangya Hospital, Molecular Biology Research Center, School of Life Sciences, Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha, China
²Department of Hematology, Xiangya Hospital, Central South University, ChangSha, China
³The First Affiliated Hospital, Department of Clinical Laboratory Medicine, Institution of Microbiology and Infectious Diseases, Hengyang Medical School, University of South China, Hengyang, China
⁴Research Laboratory of Red Cell Physiology, New York Blood Center, New York
⁵Department of Hematology, the Second Xiangya Hospital, Central South University, Changsha, China

Emmanuel Olivier, PhD^*, Zi Yan^*, Shouping Zhang^* and Eric E Bouhassira, PhD

Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY

Corbin R Azucenas, BS^1,2*, Maria Stewart^1*, Aikaterini Voulgaridou^1*, Katie Seu, PhD^3,4 and Theodosia A. Kalfa, MD, PhD⁴

¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²University of Cincinnati, Cincinnati, OH
³Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH
⁴Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Kathleen E. McGrath, PhD¹, Paul D. Kingsley, PhD^1*, Eli T. Rust^1*, Vincent P Schulz, PhD^2*, Anne Koniski^1*, Taylor L. Schofield^1*, Leah A. Vit^1*, Mohandas Narla, DSc³, Lionel Blanc, PhD⁴, Laurie A. Steiner, MD⁵, Patrick G Gallagher, MD^6,7 and James Palis, MD¹

¹University of Rochester, Rochester, NY
²Department of Pediatrics, Yale University School of Medicine, New Haven, CT
³Research Laboratory of Red Cell Physiology, New York Blood Center, New York
⁴Feinstein Institutes for Medical Research, Northwell, Manhasset, NY
⁵Department of Pediatrics, University of Rochester, Rochester, NY
⁶Yale University School of Medicine, New Haven, CT
⁷Dept of Pediatrics, Ohio State University, Nationwide Childrens Hospital, Columbus, OH

Kristin Murphy^1*, Deanna Abid^2*, Xiurui Lv, MBBS, MS², Zachary C. Murphy, PhD^2*, Michael Getman^2* and Laurie A. Steiner, MD²

¹University of Rochester, Rochester, NY
²Department of Pediatrics, University of Rochester, Rochester, NY

Jonathan R.A. De Wilde, MD^1*, Maryse E. Boesveld^1*, Annelies J. van Vuren^2*, Wouter W. van Solinge^1*, Eduard J. Van Beers, MD, PhD^3*, Marije Bartels^2,4*, Esmé Waanders^5*, Minke A.E. Rab^1* and Richard van Wijk¹

¹Central Diagnostic Laboratory - Research, University Medical Center Utrecht, Utrecht, Netherlands
²Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands
³Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Centre Utrecht, Utrecht, Netherlands
⁴Department of Pediatric Hematology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, Netherlands
⁵Department of Genetics, University Medical Center Utrecht, Utrecht, Netherlands

Marina Dorigatti Borges, PhD^1*, Dulcineia Albuquerque, PhD^1*, Carolina Lanaro, BSc, PhD^1*, Sara Teresinha Olalla Saad, MD¹, Katia B Pagnano, MD, PhD¹, Renata Sesti-Costa, PhD^1* and Fernando Ferreira Costa, MD, PhD²

¹Hematology and Hemotherapy Center, University of Campinas - UNICAMP, Campinas, Brazil
²Hematology and Transfusion Center, University of Campinas - UNICAMP, Campinas, Sao Paulo, Brazil

Julien Papoin, MS^1,2*, Hongxia Yan, PhD³, Marjorie Leduc, PhD^4*, Morgane le-Gall, MS^4*, Anupama Narla, MD⁵, Laurie A. Steiner, MD⁶, Patrick G Gallagher, MD^7,8, Christopher D. Hillyer, MD^3*, Emilie-Fleur Gauthier, PhD^4*, Mohandas Narla, DSc⁹ and Lionel Blanc, PhD^1,10

¹Feinstein Institutes for Medical Research, Northwell, Manhasset, NY
²HEMATIM site CHU, University of Picardy Jules Verne, Amiens, France
³LFKRI, New York Blood Center, New York, NY
⁴Plateforme Proteom'IC Institut Cochin, Université Paris Cité, INSERM U1016, CNRS UMR8104, Paris, France
⁵Stanford University, Stanford, CA
⁶Center for Pediatric Biomedical Research, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY
⁷Yale University School of Medicine, New Haven, CT
⁸Dept of Pediatrics, Ohio State University, Nationwide Childrens Hospital, Columbus, OH
⁹LFKRI, New York Blood Center Enterprises, New York, NY
¹⁰Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY

Min Young Kim, PhD¹, Suming Huang, PhD² and Yi Qiu, PhD³

¹Department of Cellular and Molecular Physiology, Penn State University College of Medicine, Hershey, PA
²Division of Pediatric Hematology/Oncology, Pennsylvania State University College of Medicine, Hershey, PA
³Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA

Changhan Chen^1*, Tingting Xie^1*, Yujin Zhang^1*, Yiyan Wang^1*, Fang Yu^1*, Lizhen Lin^1*, Weiru Zhang^1*, Benjamin C. Brown^2*, Xin Zhang^1*, Rodney E. Kellems^3*, Angelo D'Alessandro, PhD⁴ and Yang Xia, MD, PhD^1*

¹Xiangya Hospital, Central South University, Changsha, China
²Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Denver
³The University of Texas McGovern Medical School at Houston, Houston
⁴Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO

Sara El Hoss^1*, Panicos Shangaris, PhD, MBBCHBAO², John Brewin, PhD, FRCPath, MA, MBBS, MRCP^3*, Maria Eleni Psychogyiou^4*, Cecilia Ng, BSc, FRCPath^4*, Kypros Herodotos Nicolaides, MD FRCOG^5*, Nicola Conran, PhD⁶, David C Rees, MBBS⁴ and John Strouboulis, PhD^4*

¹Red Cell Haematology Lab, School of Cancer and Pharmaceutical Sciences, King's College London, London, ENG, United Kingdom
²Women and Children's Health, School of Life Course & Population Sciences, King's College London, London, United Kingdom
³Department of Haematological Medicine, King's College Hospital, London, United Kingdom
⁴Red Cell Haematology Lab, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom
⁵Harris Birthright Research Centre of Fetal Medicine, King's College Hospital, London, United Kingdom
⁶Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo, Brazil

Jacopo Ceolan^1,2*, Katie Seu, PhD^2,3, Athina Ntoumaziou, MD^2*, Yasmin Elgammal, MD, MSc^2*, Sana Emberesh^4*, Lisa Bilston, MD⁵, Donald Richards, MD^6*, Kathryn E. Dickerson, MD, MS⁷, Satheesh Chonat, MD⁸, Natalia Rydz, MD, FRCPC⁵, Carolyn Lutzko, PhD^2,3*, Ammar Husami^9*, Wenying Zhang^3,10* and Theodosia A. Kalfa, MD, PhD^2,3

¹Department of Medicine, University of Verona, Verona, Italy
²Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
³Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH
⁴Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁵Division of Hematology and Hematological Malignancies, Department of Medicine, University of Calgary, Calgary, Canada
⁶Northeast Texas Cancer and Research Institute, Tyler, TX
⁷Division of Hematology & Oncology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX
⁸Department of Pediatrics, Emory University School of Medicine and Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, GA
⁹Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
¹⁰Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Francesca Cendali, BS¹, Monika Dzieciatkowska, Ph.D^2*, Christina Lisk, PhD^3*, David Irwin, Ph.D^3*, James C Zimring, MD, PhD^4*, Karolina Dziewulska-Cronk^4*, Travis Nemkov, PhD^3* and Angelo D'Alessandro, PhD⁵

¹University of Colorado School of Medicine, Anschutz, Aurora, CO
²University of Colorado Denver - Anschutz Medical Campus, Aurora, CO
³University of Colorado Anschutz Medical Campus, Aurora, CO
⁴University of Virginia School of Medicine, Charlottesville, VA
⁵Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO

Senquan Liu, PhD^1,2,3*, Enyu Wang, M.S.^2*, Xinye Zhang, B.S.^3*, An Xie, M.S.^2*, Ding Ma, PhD^1,2* and Linzhao Cheng, PhD^1,2,3,4

¹Department of Hematology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
²Blood and Cell Therapy Institute, Anhui Provincial Key Laboratory of Blood Research and Applications, University of Science and Technology of China, Hefei, Anhui, China
³School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
⁴Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD