Raymond T. Doty, PhD^*, Adam D. Munday, PhD^*, Hannah Cottnair, BS^*, Sarah E. Funk, MS^* and Janis L. Abkowitz, MD

Department of Medicine, University of Washington, Seattle, WA

Christopher M. Sande, MD¹, Stone Chen^2*, Dana V Mitchell, PhD^3*, Ping Lin^2,4*, Rujul Jagdish Deolikar^2*, Colby Freeman^2*, Mary Zhou^2*, Sushant Kumar, PhD^2*, Shannon Zheng^2*, Bolormaa Munkhbileg, MD, MMS^2,4*, Natasha L Stanley^2,5, Kathy Guo^2*, Ryan Hausler, MS^2*, Deanne M Taylor, PhD^3,6*, James Corines, DO^1*, Jennifer JD Morrissette, PhD^1*, David B Lieberman^1*, Guang Yang, MD, PhD^1*, Kelcy Smith-Simmer, MMSc, CGC^7*, Lauren G Banaszak, MD⁷, Kyle Shoger^7*, Peter Nicholas^4,8*, Amanda J Walne, PhD^9*, Inderjeet Dokal, MD⁹, Justin Rosenheck, DO^10*, Jane E Churpek, MD, MS⁷, F Bradley Johnson, MD, PhD^1*, Timothy S Olson, MD, PhD^4,8 and Daria V Babushok, MD, PhD^2,4

¹Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA
²Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA
³Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA
⁴Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA
⁵Department of Pediatrics, Children's Hospital of Pennsylvania, Philadelphia, PA
⁶Department of Pediatrics, Hospital of the University of Pennsylvania, Philadelphia, PA
⁷Division of Hematology, Medical Oncology, and Palliative Care, Department of Medicine, University of Wisconsin-Madison, Madison, WI
⁸Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA
⁹Blizard Institute Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
¹⁰Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH

Jose Maria Bastida, MD, PhD^1*, Ana Marín-Quílez^2*, Ana Zamora^2*, Maria Rocio Benito Sanchez, PhD^3*, Agustín Rodriguez Alen^4*, Teresa Sevivas^5*, Pedro Luis Gómez-González^2*, Lorena Díaz-Ajenjo^3*, Nora Butta, PhD^6*, Rosa M. Campos^7*, Paola Escribano^8*, Jorge Huertas-Aragoneses^9*, Monica Lopez-Duarte^10*, Antonio León^11*, Angela Mompel^12*, Raquel De Oña Navarrete, MD^13*, Irene Peláez-Pleguezuelos^14*, Fernando Jesús Ramos-Ortega, MD^15*, Elena Sebastian^16*, Claudia Serrano^17*, Cristina Sierra-Aisa^18*, Pablo Velasco, MD¹⁹, Laura Murillo^19*, Rosa Vidal-Laso^20*, Meritxell Nomdedeu, MD^21*, Jordi Esteve Reyner, MD^22*, Jesús María Hernández-Rivas, PhD²³, Jose Rivera Pozo, PhD^2* and Maria Luisa Lozano, MD, PhD^24*

¹Hematology, Complejo Asistencial Universitario de Salamanca (CAUSA), Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, Spain
²Centro Regional de Hemodonación, Murcia, Spain
³Hospital Universitario De Salamanca (CAUSA), Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, Spain
⁴Servicio De HematologíA Y Hemoterapia, Hospital Virgen De La Salud, Compl, Toledo, ESP
⁵Complejo Hospitalario de Coimbra, Coimbra, Portugal
⁶IdiPAZ, Madrid, Spain
⁷Hospital Universitario de Jerez de la Frontera, Jerez de la Frontera, Spain
⁸Hospital General Río Carrión, Palencia, Spain
⁹Hospital Materno-Infantil Gregorio Marañón, Madrid, Spain
¹⁰University Hospital Marqués De Valdecilla - IDIVAL, Santander, ESP
¹¹Hospital General de La Gomera, La Gomera, Spain
¹²Hospital General Universitario de Elche, Elche, Spain
¹³Hospital MD Anderson Cancer Center, Madrid, AL, ESP
¹⁴Hospital Universitario Virgen de las Nieves, Granada, Spain
¹⁵Hospital Universitario de León, León, Spain
¹⁶Hospital Infantil Universitario Niño Jesús, Madrid, ESP
¹⁷Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
¹⁸Hospital Universitario de Cruces, Barakaldo, Spain
¹⁹Hospital Universitario Vall d'Hebron, Barcelona, Spain
²⁰Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain
²¹Hematopoietic Cell Transplantation Unit, Hospital Clínic de Barcelona, ICHMO, Barcelona, Spain
²²Hospital Clínic de Barcelona, Barcelona, Spain
²³Department of Medicine, Hematology Department, Hospital Universitario de Salamanca, Salamanca, Spain
²⁴Servicio de Hematología, Hospital General Universitario Morales Messeguer, Centro Regional de Hemodonación, IMIB-Pascual Parrilla, CIBERER-ISCIII, Universidad de Murcia, Murcia, Spain

Nicholas F. DeCleene, BS^1,2, Elif Asik, PhD^1,2*, Anthony Sanchez, PhD^3*, Nimrat Chatterjee, PhD^1,2*, Kyle M. Miller, PhD^3*, Yu-Hsiu Wang, PhD^4* and Alison A. Bertuch, MD, PhD^2,5

¹Department of Pediatrics, Baylor College of Medicine, Houston, TX
²Cancer and Hematology Center, Texas Children's Hospital, Houston, TX
³Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX
⁴Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX
⁵Hematology/Oncology, Baylor College of Medicine, Houston, TX

Liying Guan, PhD^1*, Fabiola Del Carpio-Cano^1*, Deepak Voora, MD^2*, Rachel Myers, PhD^2* and Angara Koneti Rao, MBBS³

¹Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA
²Duke University, Durham, NC
³Sol Sherry Thrombosis Research Center and Hematology Division, Lewis Katz School of Medicine, Temple University, Philadelphia, PA

Marta Bortolotti^1*, Roochi Trikha^2*, Sarah Salter^3*, Joanna Large^4*, Shreyans Gandhi^5*, Bruno Fattizzo, MD⁶, Wilma Barcellini, MD^7* and Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP⁸

¹FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO and UNIVERSITY OF MILA, MILANO, Italy
²King's College Hospital NHS Foundation Trust, London, GBR
³King's College Hospital, London, GBR
⁴King's College Hospital NHS Foundation Trust, London, United Kingdom
⁵Department of Haematological Medicine, King's College Hospital NHS, London, United Kingdom
⁶Department of Oncology and Onco-hematology, FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Milano, Italy
⁷Hematology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
⁸Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, ENG, United Kingdom

Brijendra Singh, PhD^1*, Carlo Salas Salinas^2*, Md Akram Hossain, PhD^2*, Christopher Millington, PhD^3*, Ketan Patel^4* and Wei Tong, PhD^1,5

¹Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
²Children's Hospital of Philadelphia, Philadelphia, PA
³MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
⁴3MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
⁵Division of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Damian Krzyzanowski, PhD^1*, Sushree S Sahoo, PhD¹, Lili Kotmayer, MD, PhD^1*, Masanori Yoshida, MD, PhD^2*, Majd Khiami, MD¹, Alessandra Giorgetti, PhD^3*, Shengdar Q Tsai, PhD¹, Senthil V. Bhoopalan, MBBS, PhD^4*, Jonathan S Yen, PhD¹ and Marcin W. Wlodarski, MD, PhD⁵

¹Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
²Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN
³Bellvitage Institute for Biomedical Research (IDIBELL), Barcelona, Spain
⁴St Jude Children's Research Hospital, Memphis, TN
⁵St. Jude Children's Research Hospital, Memphis, TN

Manabu Wakamatsu, MD.PhD^1*, Hideki Muramatsu, MD, PhD¹, Hironori Sato, MD.PhD^2,3*, Masaki Ishikawa^3*, Daisuke Nakajima^3*, Ryo Konno^3*, Yusuke Kawashima^3*, Motoharu Hamada, MD.PhD^4*, Yusuke Okuno, MD, PhD^4*, Osamu Ohara^3* and Yoshiyuki Takahashi, MD, PhD¹

¹Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan
²Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan
³Department of Applied Genomics, Kazusa DNA Research Institute, Chiba, Japan
⁴Department of Virology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

Apichat Photia, M.D.^1,2,3*, Mariana Benicio, PhD^1*, Efe Sahinoglu^4,5*, Hongbing Li^1,3*, Richard Neil Armstrong, PhD, BSc^6*, Houtan Moshiri^7*, Robert J. Klaassen, MD, FRCPC⁸, Yves D Pastore, MD⁹, John E. Dick, PhD^10,11 and Yigal Dror, MD, FRCPC^1,3,12

¹Genetics & Genome Biology Program, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada
²Hematology Program, Division of Hematology/Oncology, Department of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand
³Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
⁴Genetics & Genome Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Canada
⁵Department of Cell & Systems Biology, University of Toronto, Troronto, ON, Canada
⁶Genetics & Genome Biology Program, Research Institute, The Hospital for Sick Children, Toronto, ON, CAN
⁷Hospital For Sick Children, Toronto, ON, CAN
⁸Division of Hematology/Oncology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada
⁹CHU Sainte-Justine, Montreal, QC, Canada
¹⁰Department of Molecular Genetics, University of Toronto, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, CAN
¹¹Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
¹²Institute of Medical Science, University of Toronto, Toronto, ON, Canada

Rachel A Simon^1*, Christy M Finke^2*, Terra L. Lasho, PhD², Christopher T. Schmitz^3*, Jenna A Fernandez, PhD⁴, Eva M Carmona-Porquera^4*, Mark E Wylam, M.D.^5*, Thomas E. Witzig, MD⁴, Tammy M McAllister, M.A.^6*, Carolyn R. Rohrer Vitek, Ed.D. / M.S.^6*, Konstantinos N Lazaridis^4*, Abhishek A Mangaonkar, MBBS¹, Mrinal M. Patnaik, MD, MBBS¹ and Alejandro Ferrer, PhD⁴

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
³Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN
⁴Mayo Clinic, Rochester, MN
⁵Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN
⁶Center for Individualized Medicine, Mayo Clinic, Rochester, MN

Lili PAN, MD, PhD^1,2*, Yining Li^2*, Huiying Gao, MD^2*, Yuanhua Cai, MD, PhD^1,2*, Xiaolin Lai, MD, PhD^1,3*, Zhixiang Chen, MD^1,2*, Xiaofan Li, MD, PhD^1,2 and Shaoyuan Wang, MD^1,2*

¹Department of Hematology, Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, China
²Union Clinical Medical Colleges, Fujian Medical University, Fuzhou, China
³Fujian Medical University Union Hospital，Fujian Institute of Hematology, Fuzhou, China