Shinpei Harada^1*, Daigo Hashimoto, MD, PhD², Yumika Saito, MD^3*, Toru Miyajima, MD^3*, Wenyu Li^3*, Hajime Senjo, MD⁴, Zixuan Zhang^3*, Ryo Kikuchi^3*, Masahiro Chiba^3*, Hiroyuki Ohigashi^3*, Takahide Ara, MD, PhD^3*, Masao Nakagawa, MD, PhD³ and Takanori Teshima, M.D., Ph.D.³

¹Department of Hematology, Hokkaido University Faculty of Medicine and Graduate School of Medicine, Sapporo City, Japan
²Hokkaido University Hospital, Sapporo, Japan
³Department of Hematology, Hokkaido University Faculty of Medicine and Graduate School of Medicine, Sapporo, Japan
⁴Department of Hematology, Hokkaido University, Kita-Ku, Japan

Taisuke Kondo, PhD¹, François Bourassa^2*, Sooraj Achar, B.S.^3*, Justyn DuSold^1*, Pablo Cespedes^4*, Madison Wahlsten, B.S.^5*, Audun Kvalvaag^4*, Guillaume Gaud^6*, Paul Love, MD, PhD^7*, Michael Dustin, PhD^8*, Gregoire Altan-Bonnet, Ph.D.^3*, Paul François^2* and Naomi Taylor, M.D., Ph.D.⁹

¹Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD
²Université de Montréal, Montréal, Canada
³National Cancer Institute, Bethesda, MD
⁴University of Oxford, Oxford, United Kingdom
⁵National Cancer Institute, Bethesda
⁶Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda
⁷NICHD/NIH, Bethesda, MD
⁸The Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom
⁹Pediatric Oncology Branch, National Institutes of Health, Bethesda, MD

Stefanie Bachl, MD^1,2*, Alexis Talbot, MD^1,2*, Carter Ching^1,2*, Nupura Kale^1,2*, Zhongmei Li^2*, Morgan Diolaiti, PhD^3*, Amy Peixin Chen^1,2*, Joseph Muldoon, PhD^1,2*, Chang Liu^1,2*, Thomas Martin, MD^1,3, Justin Eyquem, PhD^1,2,3,4,5* and Julia Carnevale, MD^1,2,5*

¹Department of Medicine, University of California, San Francisco, CA
²Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA
³UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA
⁴Department of Microbiology and Immunology, University of California, San Francisco, CA
⁵Parker Institute for Cancer Immunotherapy, University of California, San Francisco, CA

Janaki Manoja Vinnakota^1*, Francesca Biavasco^2*, Marius Schwabenland^3*, Chintan Chhatbar^4*, Rachael C Adams^5,6,7*, Daniel Erny^4*, Sandra Duquesne^8*, Nadia El Khawanky^9*, Henrike Salié^10*, Dimitrios Athanassopoulos^8*, Lukas Braun^8,11*, Dominik Schmidt^11,12*, Viktor Fetsch^11*, Rebeka N. Javorniczky^8*, Jenny N.H.G Ho^8*, Reinhard Marks, MD^13*, Ralph Wäsch, MD¹³, Federico Simonetta, MD, PhD^14*, Geoffroy Andrieux^15*, Dietmar Pfeifer, PhD^16*, Gianni Monaco^17,18*, Christian Capitini^19*, Terry J. Fry, MD²⁰, Thomas Blank^4*, Bruce R Blazar, MD²¹, Eva-Maria Wagner Drouet^22,23*, Matthias Theobald, MD²³, Clemens Sommer^24*, Matthias Stelljes, MD²⁵, Christian Reicherts, MD^26*, Astrid Jeibmann^27*, Jens Schittenhelm^28*, Camelia-Maria Monoranu^29*, Andreas Rosenwald, MD^30*, K. Martin Kortüm, MD^31*, Leo Rasche, MD^32*, Hermann Einsele^33*, Philipp Tobias Meyer^34*, Joachim Brumberg^34*, Andreas Mackensen, MD^35*, Michael von Bergwelt-Baildon, MD, PhD^36*, Roland Coras^37*, Nathalie L. Albert^38,39*, Laura M. Bartos^40*, Matthias Brendel^40,41,42*, Adrien Holzgreve^40*, Melanie Boerries, MD, PhD^43,44*, Crystal L. Mackall, MD⁴⁵, Justus Duyster, MD^13*, Natalie Koehler, PhD^46*, Felix Strübing^47*, Bertram Bengsch^48*, Marco Ruella, MD⁴⁹, Marion Subklewe, MD^50,51, Louisa von Baumgarten^52*, Saar Gill, MD, PhD^53,54, Marco Prinz, MD^55,56,57* and Robert Zeiser, MD^6,44,58

¹Department of Medicine I - Medical centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany, University Medical Center Freiburg, Freiburg, Germany
²Department of Medicine1, Univeresity Medical Centre Freiburg, Freiburg, DEU
³Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, DEU
⁴Institute for Neuropathology, Medical Faculty, University of Freiburg, Germany, Freiburg, Germany
⁵QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia
⁶Department of Medicine I, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany
⁷Faculty of Medicine, The University of Queensland, Brisbane, Australia
⁸Department of Medicine I - Medical centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany, Freiburg, Germany
⁹6Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany, Munich, Germany
¹⁰Department of Medicine II - Medical centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany, Freiburg, Germany
¹¹Faculty of Biology, University of Freiburg, Freiburg, Germany
¹²University Medical Center Freiburg, Freiburg, DEU
¹³Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany
¹⁴Division of Oncology and Hematology, University Hospital Geneve, Geneve, Switzerland
¹⁵Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Germany, Freiburg, Germany
¹⁶University Clinics Medical Center, Freiburg, DEU
¹⁷Medical Center - University of Freiburg, Freiburg Im Breisgau, DEU
¹⁸Single-Cell Omics Platform Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Freiburg, Germany
¹⁹Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD., Bethesda
²⁰CCR, NCI NIH, Aurora, CO
²¹Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN
²²III. med. Klinik, Mainz, DEU
²³Department of Internal Medicine III, University Medical Center Mainz, Mainz, Germany
²⁴Institute of Neuropathology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany, Mainz, Germany
²⁵Department of Internal Medicine A, University of Muenster, Muenster, Germany
²⁶Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany
²⁷Institute of Neuropathology, University Hospital Münster, Münster, Germany, Muenster, Germany
²⁸Department of Neuropathology, Institute of Pathology and Neuropathology, Eberhar, TüBingen, DEU
²⁹Institute of Pathology, Wuerzburg, DEU
³⁰Institute of Pathology, Julius-Maximilians-Universität Würzburg, Wuerzburg, Germany
³¹Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany, Würzburg, Germany
³²Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany
³³Division of Hematology, University Hospital of Wurzburg, Wurzburg, Germany, WüRzburg, DEU
³⁴Department of Nuclear Medicine - Medical centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany, Freiburg, Germany
³⁵Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Erlangen, Germany
³⁶Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
³⁷Department of Neuropathology, University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany
³⁸Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany, Muncih, Germany
³⁹German Cancer Consortium (DKTK), partner site Munich, German Cancer Research Center (DKFZ), Heidelberg, Germany, Munich, Germany
⁴⁰Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany, Munich, Germany
⁴¹German Center for Neurodegenerative Diseases (DZNE), Munich, Germany, Munich, Germany
⁴²Munich Cluster for Systems Neurology (SyNergy), Munich, Germany, Munich, Germany
⁴³Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
⁴⁴German Cancer Consortium (DKTK), Partner site Freiburg; and German Cancer Research Center (DKFZ), Heidelberg, Germany
⁴⁵Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University, Stanford, CA
⁴⁶Department of Internal Medicine III, Johannes Gutenberg-University Mainz, Mainz, Germany, Freiburg, Germany
⁴⁷Center for Neuropathology and Prion Research, University Hospital, LMU Munich, Munich, Germany, Munich, Germany
⁴⁸University Hospital Freiburg, Freiburg, DEU
⁴⁹Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
⁵⁰German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany
⁵¹Department of Medicine III, LMU University Hospital, LMU Munich, Muenchen, Bavaria, Germany
⁵²Division of Neuro-Oncology, Department of Neurosurgery, University Hospital, LMU Munich, Munich, Germany, Munich, Germany
⁵³Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
⁵⁴Center for Cellular Immunotherapies, University of Pennsylvania School of Medicine, Philadelphia, PA
⁵⁵Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany
⁵⁶Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany
⁵⁷Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany
⁵⁸University of Freiburg, CIBSS – Centre for Integrative Biological Signalling Studies, Freiburg im Bresigau, Germany

Yongxian HU^1*, Xia Li^2,3*, Penglei Jiang⁴, Tingting Yang^5*, Tianning Gu^6*, Xiaohui Si, PhD^7*, Yali Xie^8*, Mingming Zhang^9*, Guoqing Wei^5*, Huijun Xu^6*, Zenan Cen^8*, Jiazhen Cui^6*, Simao Huang^6*, Fang Ni^10*, Linqin Wang^10*, Xiujian Wang, MD, PhD^8*, Xiangjun Zeng^11*, Delin Kong^10*, Houli Zhao^6*, Alex H. Chang^12*, Yanlei Zhang^13*, Jin Zhang^14*, Jinyan Huang^8*, Pengxu Qian, PhD^15* and He Huang^16*

¹Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, HANGZHOU, China
²The First Affiliated Hospital, Zhejiang University School of Medicine, Hang zhou, China
³The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁴Institute of Hematology, Zhejiang University, Hangzhou, China
⁵Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁶Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁷The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, AL, China
⁸the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁹Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang, China
¹⁰The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, CHN
¹¹The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., HANGZHOU, China
¹²Shanghai YaKe Biotechnology Ltd., Shanghai, China, Hangzhou, China
¹³Shanghai Yake Biotechnology Ltd., Shanghai, CHN
¹⁴Department of Hematology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
¹⁵Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China
¹⁶Bone Marrow Transplantation Center, Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China, Hangzhou, China

Ruchi P. Patel, MS¹, Guido Ghilardi, MD^1*, Yunlin Zhang, MS^2*, Puneeth Guruprasad^3*, Mathew G. Angelos, MD, PhD¹, Raymone Pajarillo, MS^2*, Khatuna Gabunia^2*, Chong Xu^2*, Tatiana Blanchard^2*, John Scholler^2*, Patrizia Porazzi, PhD^2*, Gerald Linette, MD, PhD^2*, Beatriz M. Carreno, PhD^4* and Marco Ruella, MD¹

¹Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
²Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
³Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, North Wales, PA
⁴Parker Institute for Cancer Immunotherapy and Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA