Elizabeth Hill, MD^1*, Joseph L. Roswarski, MD², Amrit Bhaskarla, DO^3*, Alexander Dew, DO, MS^4*, Candis Morrison, NP, PhD^5*, Michael Emanuel^6*, Ani Petrosyan^6*, Hao-Wei Wang, MD, PhD^7*, Constance M. Yuan, MD, PhD^7*, Liza Lindenberg, MD^8*, Esther Mena, MD^8*, Baris Turkbey, MD^8*, Nisha Patel, DO⁹, Irina Maric, MD, MSc¹⁰, Alina Dulau-Florea, MD^9*, Katherine Calvo, MD, PhD¹¹, Raul C. Braylan, MD¹², Maryalice Stetler-Stevenson, MD, PhD^13*, Seth M. Steinberg, PhD^14*, William Figg, PharmD^15*, Ryan M. Young, PhD^5*, Ola Landgren, MD¹⁶, Mark Roschewski, MD⁵ and Dickran Kazandjian, MD^17,18

¹National Cancer Institute, National Institutes of Health, Bethesda, MD
²Hematologic Malignancies Department, Medstar Georgetown University Hospital, Washington, DC
³NIH/NCI, Bethesda, MD
⁴Walter Reed National Military Medical Center, Bethesda, MD
⁵Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁶Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁷Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁸Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁹Hematology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD
¹⁰DLM/CC/NIH, Bethesda, MD
¹¹National Institutes of Health Clinical Center, Bethesda, MD
¹²National Institutes of Health, Bethesda, MD
¹³NCI, NIH, Bethesda, MD
¹⁴Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD
¹⁵Molecular Pharmacology Section, Genitourinary Malignancies Section, Center for Cancer Research, National Cancer Institute,, National Institutes of Health, Bethesda, MD
¹⁶Sylvester Comprehensive Cancer Center, Myeloma Division, University of Miami, Miami, FL
¹⁷Center for Cancer Research, Lymphoid Malignancies Branch, Multiple Myeloma Program, NIH, Potomac, MD
¹⁸Myeloma Service, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL

Nizar J Bahlis, MD^1,2, Hang Quach, MD, FRACP, FRCPA, MBBS³, Rachid Baz, MD⁴, Annette Vangsted^5*, Shir-Jing Ho^6*, Niels Abildgaard⁷, Jacob Laubach⁸, Vincent Ribrag, MD⁹, Peter M. Voorhees, MD¹⁰, Xifeng Wang^11*, Orlando Bueno, MD, PhD¹², Yan Luo^11*, Jeremy A Ross, PhD^12* and Jonathan L. Kaufman, MD¹³

¹Department of Hematology and Oncology, Tom Baker Cancer Center, University of Calgary, Calgary, AB, Canada
²Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada
³St. Vincent's Hospital Melbourne, East Melbourne, Australia
⁴H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁵Department of Hematology, Rigshospitalet, Copenhagen, Denmark
⁶St George & Sutherland Clinical School, Kogarah, Australia
⁷Haematology Research Unit, Department of Haematology, Odense University Hospital, Odense, Denmark
⁸Dana-Farber/Partners CancerCare, Harvard Medical School, Boston, MA
⁹Département d'Innovation Thérapeutique et d'Essais Précoces (DITEP), Gustave Roussy Institute of Cancer,, Villejuif, France
¹⁰Department of Hematologic Oncology & Blood Disorders, Atrium Health Levine Cancer Institute, Charlotte, NC
¹¹AbbVie, Inc., North Chicago, IL
¹²AbbVie Inc., North Chicago, IL
¹³Winship Cancer Institute, Emory University, Atlanta, GA

Carmen Gonzalez, MS^1*, Marta Lasa, PhD^1*, Laura Notarfranchi^1,2*, Cristina Agullo^3*, Natalia Buenache Cuenda^4*, Anastasiia Zherniakova^1*, Sergio Castro^3*, José Juan Pérez^3*, Veronica Gonzalez-Calle, MD, PhD^3*, Maria Teresa Cedena Romero, MD, PhD^4*, Santiago Barrio^4,5*, Alejandro Martín-Muñoz^4,5*, Leire Burgos^1*, Diego Alignani^1*, Maria Jose Calasanz, PhD^1*, Paula Rodriguez Otero, MD, PhD^1*, Laura Rosiñol, MD, PhD^6*, Felipe De Arriba, MD, PhD^7*, Enrique M Ocio, MD, PhD⁸, Albert Oriol Rocafiguera, MD^9*, Luis Palomera, MD, PhD^10*, Yolanda González-Montes, MD^11*, Anna Maria Sureda Balari, MD, PhD¹², Miguel Teodoro Hernandez Garcia^13*, Maria Esther Clavero Sanchez^14*, Angela Ibanez Garcia^15*, Clara Gomez, MD^16*, Alberto Orfao, MD, PhD^17*, Maria Victoria Mateos, MD, PhD³, Juan Jose Lahuerta Palacios^4*, Joan Bladé, MD, PhD^18*, Jesus San-Miguel, MD, PhD¹, Joaquin Martinez-Lopez, MD, PhD^4*, Noemi Puig, MD, PhD³ and Bruno Paiva^1*

¹Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), IDISNA, CIBER-ONC number CB16/12/00369 and CB16/12/00489, Pamplona, Spain
²University of Parma, Parma, ITA
³Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain
⁴Hospital Universitario 12 de Octubre, CIBER-ONC CB16/12/00369, CNIO, Madrid, Spain
⁵Altum Sequencing Co., Madrid, Spain
⁶Amyloidosis and Multiple Myeloma Unit, Department of Hematology, IDIBAPS, Hospital Clinic, Barcelona, Spain
⁷Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
⁸Hospital Universitario Marques de Valdecilla, IDIVAL, Santander, Spain
⁹Institute of Oncology and Josep Carreras Institute, Hospital Germans Trias i Pujol, Badalona, Spain
¹⁰Hospital Clinico Universitario Lozano Blesa, Instituto Investigacion Sanitaria Aragon, Zaragoza, Spain
¹¹Institut d'Oncologia Dr. Josep Trueta, Girona, Spain
¹²Hospital Duran i Reynals, Institut d’Investigacio Biomedica de Bellvitge (IDIBELL), Universitat de Barcelona, Barcelona, Spain, Barcelona, Spain
¹³Hospital Universitario de Canarias, La Laguna. Santa Cruz De Tenerife, ESP
¹⁴Hematology, Hospital Virgen de las Nieves, Granada, ESP
¹⁵Hematology Department, Complejo Hospitalario Universitario de Albacete, Albacete, ESP
¹⁶Hospital Universitario de Galdakao, Galdakano, Spain
¹⁷Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), Cytometry Service (NUCLEUS) and Department of Medicine, University of Salamanca, Salamanca, Spain
¹⁸Hospital Clínic de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona and GEM/PETHEMA, Barcelona, Spain

Tadeusz Kubicki^1,2*, Dominik Dytfeld^2*, David Barnidge^3*, DJ Sakrikar^3*, Gabriella Lakos⁴, Anna Przybylowicz-Chalecka^2*, Krzysztof Jamroziak^5*, Pawel Robak^6*, Jaroslaw Czyz^7*, Agata Tyczynska^8*, Agnieszka Druzd-Sitek^9*, Krzysztof Giannopoulos^10*, Tomasz Wrobel, MD, PhD^11*, Adam Nowicki^2*, Tomasz Szczepaniak^2*, Anna Lojko-Dankowska^2*, Magdalena Matuszak^2*, Lidia Gil², Bartosz Michal Pula^5*, Lukasz Szukalski^7*, Agnieszka Konska^5*, Jan M. Zaucha^8*, Jan Walewski⁹, Damian Mikulski^6*, Olga Czabak^12*, Tadeusz Robak^6*, Ken Jiang^1*, Jennifer H Cooperrider¹, Andrzej J Jakubowiak, MD, PhD¹ and Benjamin A Derman¹

¹University of Chicago, Chicago, IL
²Poznan University of Medical Sciences, Poznan, Poland
³The Binding Site, Rochester, MN
⁴The Binding Site, Birmingham, United Kingdom
⁵Institute of Hematology and Blood Transfusion, Warsaw, Poland
⁶Medical University of Lodz, Lodz, Poland
⁷Nicolaus Copernicus University in Torun Ludwik Rydygier, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland
⁸Medical University of Gdansk, Gdansk, Poland
⁹Maria Sklodowska-Curie National Research Institute of Oncology, Warszawa, Poland
¹⁰Department of Experimental Hematooncology, Medical University of Lublin, Lublin, Poland
¹¹Wroclaw Medical University, Wroclaw, Poland
¹²Medical University of Lublin, Lublin, Poland

Yael C. Cohen^1*, Mor Zada, MSc^2*, Shuang-Yin Wang^3*, Assaf Weiner, PhD^4*, Natan Melamed^5*, Polina Stepensky^6,7*, Moshe E Gatt, MD^8,9, Shlomit Kfir-Erenfeld^6*, Nathalie Asherie^6,7*, Eyal Lebel^10,11*, Irit Avivi Mazza, MD^12,13*, Anna Gurevich Shapiro, MD, MPhil^2,14*, Iuliana Vaxman, MD^15,16*, Tamir Shragai, MD^5,12*, Paulina Chalan, PhD^2*, Eyal David^2* and Ido Amit, PhD^2*

¹Tel -Aviv Sourasky (Ichilov) Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
²Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel
³Weimann Institute of Sceince, Rehovot, Israel
⁴Weizmann institute of Science, Rehovot, Israel
⁵Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
⁶Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Medical Center, Jerusalem, Israel
⁷Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel
⁸Department of Hematology, Hadassah Medical Center, Jerusalem, Israel
⁹Department of Hematology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
¹⁰Faculty of Medicine, the Hebrew University, Jerusalem, Jerusalem, Israel
¹¹Hematology Department, Hadassah Medical Center, Jerusalem, Jerusalem, Italy
¹²Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
¹³Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
¹⁴Department of Systems Immunology, Weizmann Institute of Science, Tel Aviv, AL, Israel
¹⁵Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, tel aviv, Israel
¹⁶Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, MN, Israel

Febe Smits, MD^1,2*, Kaz Groen, MD^1,2*, Mark-David Levin, MD, PhD³, Claudia Stege, MD, PhD^1,2*, Roel JW Van Kampen, MD PhD⁴, Ellen Van Der Spek, MD, PhD^5*, Yavuz M Bilgin, MD, PhD^6*, Noortje Thielen, MD, PhD^7*, Inger S. Nijhof, MD, PhD^8*, Inge Ludwig, MD, MSc^9*, Esther G.M. De Waal, MD^10*, Yorick Sandberg, MD PhD^11*, Alain Kentos, MD^12*, Gert Jan Timmers, MD, PhD^13*, Josien C Regelink, MD^14*, Matthijs Westerman, MD^15*, Koen de Heer, MD, PhD^16*, Marie Christiane Vekemans, MD^17*, Nazik Durdu-Rayman, MD, PhD^18*, Nicole de Graauw, MD, PhD^19*, Maarten R. Seefat, MD^1,2*, Niels W.C.J van de Donk, MD, PhD^1,2*, Paula F Ypma, MD, PhD^20*, Kazem Nasserinejad, PhD^21,22* and Sonja Zweegman, MD, PhD^1,2

¹Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²Treatment and Quality of Life, Cancer Center Amsterdam, Amsterdam, Netherlands
³Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
⁴Department of Internal Medicine, Zuyderland Medical Center, Sittard-Geleen, NLD
⁵Department of Internal Medicine, Rijnstate Hospital, Arnhem, Netherlands
⁶Department of Internal Medicine, ARDZ, Goes, Netherlands
⁷Department of Internal Medicine, Diakonessenhuis, Utrecht, Netherlands
⁸Department of Internal Medicine, Antonius Hospital, Nieuwegein, Netherlands
⁹Department of Hematology, Bernhoven Hospital, Uden, Netherlands
¹⁰Department of Internal Medicine, Medical Center Leeuwarden, Leeuwarden, Netherlands
¹¹Department of Internal Medicine, Maasstad Hospital, Rotterdam, Netherlands
¹²Department of Hematology, Jolimont Hospital, Haine Saint Paul, Belgium
¹³Department of Internal Medicine, Amstelland Hospital, Amstelveen, Netherlands
¹⁴Department of Internal Medicine, Meander Medical Center, Amersfoort, Netherlands
¹⁵Department of Internal Medicine, Northwest Clinics, Alkmaar, Netherlands
¹⁶Department of Internal Medicine, Flevoziekenhuis, Almere, Netherlands
¹⁷Department of Hematology, Saint-Luc Hospital, Brussels, Belgium
¹⁸Department of Internal Medicine, Franciscus Hospital, Schiedam, Netherlands
¹⁹Department of Internal Medicine, Bravis Hospital, Roosendaal, Netherlands
²⁰Department of Hematology, HagaZiekenhuis, Den Haag, Netherlands
²¹Department of Hematology, Erasmus MC, University Medical Center, Rotterdam, Netherlands
²²Innovative Statistical Consulting, Therapeutics Development Team, Cytel Inc., Rotterdam, Netherlands