Guillermo Garcia-Manero, MD¹, Uwe Platzbecker, MD², Valeria Santini, MD^3*, Amer M. Zeidan, MBBS, MHS⁴, Pierre Fenaux, MD, PhD⁵, Rami S. Komrokji, MD⁶, Jake Shortt^7*, David Valcarcel^8*, Anna Jonasova^9*, Sophie Dimicoli-Salazar^10*, Ing Soo Tiong^11*, Chien-Chin Lin, MD, PhD^12*, Jiahui Li, PharmD¹³, Jennie Zhang^13*, Ana Carolina Giuseppi^13*, Sandra Kreitz^14*, Veronika Pozharskaya^13*, Karen L. Keeperman^13*, Shelonitda Rose^13*, Thomas Prebet^13*, Andrius Degulys^15,16*, Stefania Paolini^17*, Thomas Cluzeau, M.D.^18* and Matteo Giovanni Della Porta, MD^19,20*

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases, University Leipzig Medical Center, Leipzig, Germany
³MDS Unit, DMSC, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy
⁴Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, Yale University, New Haven, CT
⁵Hôpital Saint-Louis, Université Paris 7, Paris, France
⁶Moffitt Cancer Center, Tampa, FL
⁷Monash University and Monash Health, Melbourne, VIC, Australia
⁸Hospital Universitari Vall d'Hebron, Barcelona, Spain
⁹Medical Department Hematology, Charles University General University Hospital, Prague, Czech Republic
¹⁰Hôpital Haut-Lévêque, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France
¹¹Malignant Haematology & Stem Cell Transplantation, The Alfred, Melbourne, VIC, Australia
¹²Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan
¹³Bristol Myers Squibb, Princeton, NJ
¹⁴Celgene International Sàrl, a Bristol-Myers Squibb Company, Boudry, Switzerland
¹⁵Hematology, Oncology and Transfusion Medicine Center, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania
¹⁶Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
¹⁷IRCCS Azienda Ospedaliero-Universitaria di Bologna - Istituto di Ematologia “Seràgnoli”, Bologna, Italy
¹⁸Département d'Hématologie Clinique, Université Cote d'Azur, CHU Nice, Nice, France
¹⁹Cancer Center IRCCS Humanitas Research Hospital, Milan, Italy
²⁰Department of Biomedical Sciences, Humanitas University, Milan, Italy

Rami S. Komrokji, MD¹, Valeria Santini, MD^2*, Pierre Fenaux, MD, PhD³, Michael R. Savona, MD^4*, Yazan F. Madanat, MD⁵, Tymara Berry, MD^6*, Laurie Sherman, BSN⁶, Shyamala Navada, MD^6*, Faye M. Feller, MD⁶, Libo Sun, PhD^6*, Qi Xia, PhD^6*, Ying Wan, MD, PhD^6*, Fei Huang, PhD⁶, Amer M. Zeidan, MBBS, MHS⁷ and Uwe Platzbecker, MD⁸

¹Moffitt Cancer Center, Tampa, FL
²MDS UNIT, DMSC, Azienda Ospedaliero-Universitaria Careggi & University of Florence, Florence, Italy
³Hôpital Saint-Louis, Université Paris 7, Paris, France
⁴Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN
⁵Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
⁶Geron Corporation, Parsippany, NJ
⁷Yale School of Medicine and Yale Cancer Center, Yale University, New Haven, CT
⁸Cellular Therapy and Hemostaseology, Leipzig University Hospital, Leipzig, Germany

Moshe Mittelman, MD¹, David H. Henry², John Glaspy^3*, Anil Tombak^4*, Rosemary Anne Harrup^5*, Krzysztof Madry, MD, PhD^6*, Barbara Grabowska^7*, Uwe Platzbecker, MD⁸, Tyson Lee^9* and Katharina Modelska^9*

¹Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv, Israel
²Hospitals of the University of Pennsylvania‒Penn Presbyterian, Philadelphia
³University of California‒Los Angeles, Los Angeles
⁴Mersin University Medical Faculty, Mersin, Turkey
⁵Royal Hobart Hospital, Tasmania, Australia
⁶Medical University of Warsaw, Warsaw, Poland
⁷Centrum Medyczne PROMED, Krakow, Poland
⁸University Hospital of Leipzig, Leipzig, Germany
⁹FibroGen, Inc., San Francisco, CA

Maria Diez-Campelo, MD, PhD^1*, David M. Ross, MBBS, PhD, FRACP, FRCPA^2*, Aristoteles Giagounidis³, Shuhying Tan, FRACP, FRCPA, MBBS^4*, Thomas Cluzeau, MD, PhD⁵, Lynette C.Y. Chee, MBBS, PhD, FRACP, FRCPA⁶, David Valcarcel, MD, PhD⁷, Montserrat Arnan, MD, PhD^8*, Christine Graham, PhD^9*, Allie McGinty^9*, Miranda Ross, BS^9*, Wei Feng^9*, Ying Jiang^9*, Suresh Bobba^9*, Montagu Hankin, MSc^9*, Christopher Rovaldi^9*, Dena Grayson, MD, PhD^9*, Simon Cooper, MBBS⁹ and Jen L. Salstrom, MD, PhD⁹

¹Universidad de Salamanca, Salamanca, Spain
²Department of Haematology, Flinders Medical Centre and University, Adelaide, SA, Australia
³Dept. Oncology, Hematology and Palliative Care, Marienhospital Düsseldorf, Düsseldorf, Germany
⁴St. Vincent's Institute of Medical Research, East Melbourne, Vic, AUS
⁵Nice University Hospital, Nice, Provence Alpes Cote d'Azur, France
⁶Department of Clinical Haematology and Bone Marrow Transplant Service, The Royal Melbourne Hospital, Parkville, Australia
⁷Department of Hematology, Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain
⁸Institut Català d’Oncologia , Hospital Duran i Reynals, Barcelona, Spain
⁹Keros Therapeutics, Lexington, MA

Cristina Astrid Tentori, MD^1*, Caterina Gregorio, PhD^2*, Marie Robin, MD^3*, Nico Gagelmann^4*, Carmelo Gurnari, MD⁵, Somedeb Ball, MD⁶, Juan Carlos Caballero Berrocal, MD^7*, Luca Lanino, MD⁸, Saverio D'Amico, MSc^1*, Marta Spreafico, PhD^2*, Giulia Maggioni, MD^1*, Erica Travaglino, BS^1*, Elisabetta Sauta, PhD^1*, Manja Meggendorfer, PhD⁹, Lin-Pierre Zhao, MD^10*, Massimo Bernardi, MD^11*, Carmen Di Grazia, MD^12*, Luca Vago, MD, PhD¹³, Giulia Rivoli, MD^14*, Lorenza Maria Borin, MD^15*, Patrizia Chiusolo^16*, Luisa Giaccone, MD, PhD^17*, Maria Teresa Voso, MD¹⁸, Jan Philipp Bewersdorf, MD¹⁹, Olivier Nibourel, PhD^20*, Marina Díaz-Beyá, MD, PhD^21*, Andres Jerez, MD^22*, Francisca Maria Hernandez, MD^23*, Kyra Velázquez Kennedy, MD^24*, Blanca Xicoy, MD^25*, Marta Ubezio, MD^1*, Alessia Campagna^1*, Antonio Russo, MD^1*, Gabriele Todisco, MD^1*, Daniele Mannina, MD^1*, Stefania Bramanti^1*, Matteo Zampini, PhD^1*, Elena Riva, BSc^1*, Marilena Bicchieri, PhD^1*, Gianluca Asti, MSc^1*, Filippo Viviani, MD^1*, Alessandro Buizza, MD^1*, Benedetta Tinterri, MD^1*, Andrea Bacigalupo, MD²⁶, Alessandro Rambaldi, M.D.²⁷, Francesco Passamonti, MD^28*, Fabio Ciceri^29*, Victor Savevski, MEng^1*, Armando Santoro, MD^30*, Najla H Al Ali, MS^31*, David A Sallman, MD³², Francesc Sole, PhD³³, Guillermo Garcia-Manero, MD³⁴, Ulrich Germing^35*, Shahram Kordasti, MD, PhD³⁶, Valeria Santini, MD³⁷, Guillermo Sanz, MD, PhD^38*, Wolfgang Kern, MD⁹, Anne Sophie Kubasch, MD^39*, Uwe Platzbecker, MD⁴⁰, Maria Diez-Campelo, MD, PhD^41*, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP⁵, Lionel Ades, MD, PhD⁴², Pierre Fenaux, MD, PhD⁴³, Torsten Haferlach, MD, PhD⁹, Amer M. Zeidan, MBBS, MHS⁴⁴, Gastone Castellani, PhD^45*, Rami S. Komrokji, MD³¹, Francesca Ieva, PhD^2* and Matteo Giovanni Della Porta, MD^1*

¹Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy
²Politecnico di Milano, Milano, Italy
³Hopital Saint-Louis, Paris, France
⁴University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Hamburg, DEU
⁵Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁶Vanderbilt University Medical Center, Nashville, TN
⁷Hematology Department, Hospital Universitario de Salamanca, Salamanca, Spain, Salamanca, ESP
⁸Humanitas Clinical and Research Center, IRCCS, Rozzano, Milano, Italy
⁹MLL Munich Leukemia Laboratory, Munich, Germany
¹⁰Department of Hematology and Bone Marrow Transplantation, Hôpital Saint-Louis/Assistance Publique-Hôpitaux de Paris (AP-HP)/University Paris 7, Paris, France, Paris, FRA
¹¹Unit of Hematology and Bone Marrow Transplantation, I.R.C.C.S. Ospedale San Raffaele, Milan, Italy
¹²Hematology and Transplant Center, IRCCS Ospedale Policlinico San Martino, Genua, Italy, Genova, Italy
¹³Hematology and Bone Marrow Transplantation Unit, I.R.C.C.S. Ospedale San Raffaele, Milano, NA, Italy
¹⁴Hematology and Cellular Therapy Division, IRCCS Ospedale Policlinico San Martino, Genova, Genova, Italy
¹⁵Hematology, Ospedale San Gerardo, Monza, Italy, Monza, Italy
¹⁶Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy
¹⁷Univesity of Torino, AOU Città Della Salute E Della Scienza Di Torino,, Torino, ITA
¹⁸Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
¹⁹Department of Medicine, Section of Hematology, Yale University, New Haven, CT
²⁰Laboratory of Hematology, CHU Lille, Lille, France, Paris, FRA
²¹Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain
²²Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
²³Department of Hematology, Hospital Virgen de las Nieves, Granada, Spain
²⁴Department of Hematology, Ramón y Cajal University Hospital – IRYCIS, Madrid, Spain, Madrid, Spain
²⁵Hematology Department, Institut Català d’Oncologia, Hospital Universitari Germans Trias i Pujol, Institut de Recerca Contra la Leucèmia Josep Carreras, Universitat Autònoma de Barcelona, Badalona, Barcelona, Spain
²⁶Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
²⁷Department of Oncology and Hematology, University of Milan and Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo BG, Italy
²⁸Dipartimento di Oncologia ed Ematologia, Università degli Studi di Milano, Policlinico di Milano, Ospedale Maggiore, Fondazione I.R.C.C.S. Ca Granda, Milano, Italy
²⁹Unit of Hematology and Stem Cell Transplantation, Ospedale San Raffaele, University Vita-Salute San Raffaele, Milan, Italy
³⁰Humanitas Cancer Center, Rozzano, Mi, Italy
³¹Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
³²H. Lee Moffitt Cancer Center, Tampa, FL
³³Myelodysplastic Syndromes Research Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain
³⁴University of Texas MD Anderson Cancer Center, Houston, TX
³⁵Department of Hematology, Oncology and Clinical Immunology, Universitatsklinik Dusseldorf, Dusseldorf, Germany
³⁶King's College London, London, United Kingdom
³⁷MDS Unit, DMSC, AOU Careggi, University of Florence, Firenze, Italy
³⁸Health Research Institute La Fe, Valencia, Spain, Valencia, Spain
³⁹Department of Hematology, University Hospital of Leipzig, Dresden, Germany
⁴⁰University Leipzig Medical Center, Leipzig, Germany
⁴¹University Hospital of Salamanca, Salamanca, Spain
⁴²Saint Louis Hospital, APHP, Paris, France
⁴³Department of Hematology, Université de Paris, Saint-Louis Hospital, Paris, France
⁴⁴Section of Hematology, Department of Internal Medicine, Yale University School of Medicine - Yale Cancer Center, New Haven, CT
⁴⁵Department of Physics and Astronomy (DIFA), Bologna, Italy., Bologna, Italy

Sandra Huber, PhD^*, Natalie Wossidlo, PhD^*, Torsten Haferlach, MD, PhD, Manja Meggendorfer, PhD, Stephan Hutter, PhD^*, Gregor Hoermann, MD, PhD, Isolde Summerer^*, Henning Ruge, PhD^*, Constance Regina Baer, PhD, Wolfgang Kern, MD and Claudia Haferlach, MD

MLL Munich Leukemia Laboratory, Munich, Germany