Elsa Bernard, PhD^1*, Robert Hasserjian², Peter L. Greenberg, MD³, Juan E Arango Ossa^1*, Maria Creignou, MD^4*, Yasuhito Nannya, MD, PhD⁵, Heinz Tuechler^6*, Juan S Medina-Martínez^7*, Max F Levine^7*, Martin Jädersten, MD, PhD^8*, Ulrich Germing^9*, Guillermo Sanz, MD, PhD^10*, Arjan A. van de Loosdrecht, MD, PhD¹¹, Olivier Kosmider, PharmD, PhD^12*, Matilde Yung Follo, PhD^13*, Felicitas Thol¹⁴, Lurdes Zamora, PhD^15*, Ronald Feitosa Pinheiro, MD, PhD^16*, Andrea Pellagatti^17*, Harold K Elias, MD¹⁸, Detlef Haase, MD, PhD^19*, Maria Sirenko, PhD¹, Christina Ganster, PhD²⁰, Lionel Ades, MD, PhD²¹, Magnus Tobiasson, MD^22*, Laura Palomo, PhD^23*, Matteo Giovanni Della Porta, MD^24*, Pierre Fenaux, MD, PhD²⁵, Monika Belickova, PhD^26*, Michael R. Savona, MD²⁷, Virginia M. Klimek, MD^28*, Fabio P. S. Santos, MD²⁹, Jacqueline Boultwood, PhD^30*, Ioannis Kotsianidis, MD, PhD³¹, Valeria Santini, MD³², Francesc Sole, PhD³³, Uwe Platzbecker, MD³⁴, Michael Heuser, MD¹⁴, Peter Valent, MD³⁵, Carlo Finelli, MD^36*, Maria Teresa Voso, MD³⁷, Lee-Yung Shih, MD³⁸, Michaela Fontenay, MD, PhD^39*, Joop H. Jansen, PhD^40*, Jose Cervera, MD, PhD^41*, Norbert Gattermann, MD⁴², Benjamin L. Ebert, MD, PhD⁴³, Rafael Bejar, MD, PhD⁴⁴, Luca Malcovati, MD⁴⁵, Mario Cazzola, MD⁴⁶, Seishi Ogawa⁴⁷, Eva Hellstrom Lindberg, MD, PhD^48* and Elli Papaemmanuil, PhD¹

¹Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY
²Harvard Medical School, Boston, MA
³Stanford Cancer Center, Stanford University, Stanford, CA
⁴Phase 1 Unit, Center for Clinical Cancer Studies, Karolinska University Hospital, Stockholm, Sweden
⁵Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan
⁶LBI For Leukemia Research, Vienna, AUT
⁷Isabl Inc., New York, NY
⁸Karolinska University Hospital, Huddinge, SWE
⁹Department of Hematology, Oncology and Clinical Immunology, Universitatsklinik Dusseldorf, Dusseldorf, Germany
¹⁰Hospital Universitario y Politécnico e Instituto de Investigación Sanitaria La Fe, Valencia, Spain
¹¹Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
¹²Laboratory of Hematology, Université Paris Cité and Assistance Publique-Hôpitaux de Paris. Centre, Hôpital Cochin, Paris, France
¹³Department of Biomedical and Neuromotor Sciences, Cell Signalling Laboratory, University of Bologna, Bologna, Italy
¹⁴Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
¹⁵Hematology Department, Institut Català d’Oncologia - Hospital Universitari Germans Trias i Pujol, Institut de Recerca Contra la Leucèmia Josep Carreras, Universitat Autònoma de Barcelona, Badalona, Spain
¹⁶Department of Medicine, Columbia University Medical Center, New York, NY, Brazil
¹⁷University of Oxford, Oxford, United Kingdom
¹⁸National Institutes of Health, Bethesda, MD
¹⁹Clinics of Hematology and Medical Oncology, University Medical Center Göttingen, Georg-August- University, Goettingen, Germany
²⁰INDIGHO Laboratories, University Medical Center, Goettingen, DEU
²¹Saint Louis Hospital, APHP, Paris, France
²²Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm, SWE
²³Experimental Hematology, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain
²⁴Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy
²⁵Hôpital Saint-Louis, Hematology Department, AP-HP, Paris, France
²⁶Institute of Hematology and Blood Transfusion, Prague, Czech Republic
²⁷Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
²⁸Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
²⁹Hospital Israelita Albert Einstein, Sao Paulo, SP, BRA
³⁰Bloodwise Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
³¹Democritus University of Thrace Medical School, Alexandroupoli, Greece
³²MDS Unit, DMSC, AOU Careggi, University of Florence, Firenze, Italy
³³Myelodysplastic Syndromes Research Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain
³⁴University Leipzig Medical Center, Leipzig, Germany
³⁵Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
³⁶Institute of Hematology "Sèragnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
³⁷Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
³⁸Division of Hematology-Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan
³⁹HOPITAL COCHIN, Paris, FRA
⁴⁰Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Nijmegen, Netherlands
⁴¹Hematology Research Group, Instituto de Investigación Sanitaria La Fe, Valencia, Spain
⁴²Klinik für Hämatologie, Onkologie und Klinische Immunologie, Universitätsklinikum Düsseldorf, Düsseldorf, Germany
⁴³Department of Medicine, Harvard Medical School, Boston, MA
⁴⁴University of California, San Diego, La Jolla, CA
⁴⁵Department of Molecular Medicine, University of Pavia, Piazzale Golgi 2, Italy
⁴⁶University of Pavia, Pavia, Italy
⁴⁷Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Sakyoku, KYO, Japan
⁴⁸Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden

Luca Lanino, MD¹, Somedeb Ball, MD², Jan Philipp Bewersdorf, MD³, Monia Marchetti, MD^4*, Giulia Maggioni, MD^5*, Erica Travaglino, BS^5*, Najla H Al Ali, MS^6*, Pierre Fenaux, MD, PhD⁷, Uwe Platzbecker, MD⁸, Valeria Santini, MD⁹, Maria Diez-Campelo, MD, PhD^10*, Avani M Singh, MD^11*, Akriti Gupta Jain, MD¹², Luis E. Aguirre, MD¹³, Sara M. Tinsley-Vance, PhD, ANP¹⁴, Zaker I. Schwabkey, MD¹⁵, Onyee Chan, MD¹⁶, Zhuoer Xie, MD, MS¹⁷, Andrew M. Brunner, MD¹⁸, Andrew T. Kuykendall, MD⁶, John M. Bennett, MD¹⁹, Rena Buckstein, MD, FRCPC²⁰, Rafael Bejar, MD, PhD²¹, Hetty E. Carraway, MD, MBA²², Amy E. DeZern, MD, MHS²³, Elizabeth A. Griffiths, MD²⁴, Stephanie Halene, MD²⁵, Robert Hasserjian²⁶, Jeffrey Lancet, MD⁶, Alan F. List, MD²⁷, Sanam Loghavi, MD²⁸, Olatoyosi Odenike²⁹, Eric Padron, MD⁶, Mrinal M. Patnaik, MD, MBBS³⁰, Gail J. Roboz, MD³¹, Maximilian Stahl, MD³², Mikkael A. Sekeres, MD³³, David Peter Steensma, MD³⁴, Michael R. Savona, MD³⁵, Justin Taylor, MD³⁶, Mina Xu, MD^37*, Kendra Sweet, MD³⁸, David A Sallman, MD³⁹, Stephen D. Nimer, MD⁴⁰, Christopher S. Hourigan, DM, DPhil⁴¹, Andrew H. Wei, MBBS, PhD⁴², Elisabetta Sauta, PhD^5*, Saverio D'Amico, MSc^5*, Gianluca Asti, MSc^5*, Gastone Castellani, PhD^43*, Uma M. Borate, MD⁴⁴, Guillermo Sanz, MD, PhD^45*, Fabio Efficace, PhD^46*, Steven D. Gore, MD⁴⁷, Tae Kon Kim, MD⁴⁸, Naval Daver, MD⁴⁹, Guillermo Garcia-Manero, MD⁵⁰, María Rozman^51*, Alberto Orfao, MD, PhD^52*, Sa A. Wang⁵³, M. Kathy Foucar, MD⁵⁴, Ulrich Germing^55*, Torsten Haferlach, MD, PhD⁵⁶, Phillip Scheinberg, MD⁵⁷, Yasushi Miyazaki, MD PhD⁵⁸, Marcelo Iastrebner, MD^59*, Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP⁶⁰, Thomas Cluzeau, MD, PhD⁶¹, Shahram Kordasti, MD, PhD⁶², Arjan A. van de Loosdrecht, MD, PhD⁶³, Lionel Ades, MD, PhD⁶⁴, Amer M. Zeidan, MBBS, MHS⁶⁵, Rami S. Komrokji, MD⁶ and Matteo Giovanni Della Porta, MD^5*

¹Humanitas Clinical and Research Center, IRCCS, Rozzano, Milano, Italy
²Vanderbilt University Medical Center, Nashville, TN
³Memorial Sloan Kettering Cancer Center, New York, NY
⁴Ematologia, Ospedale Civile SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
⁵Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy
⁶Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁷Hôpital Saint-Louis, Hematology Department, AP-HP, Paris, France
⁸Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
⁹MDS Unit, DMSC, AOU Careggi, University of Florence, Firenze, Italy
¹⁰University Hospital of Salamanca, Salamanca, Spain
¹¹Department of Hematology Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa
¹²Advent Health, Orlando, Tampa, FL
¹³Dana-Farber Cancer Institute, Boston, MA
¹⁴Moffitt Cancer Center, Tampa, FL
¹⁵Malignant Hematology Department, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
¹⁶University of Arizona, Banner University Medical Center-Tucson, Tampa, FL
¹⁷Division of Hematology, Mayo Clinic, Rochester, MN
¹⁸Division of Hematology/Oncology, Dana-Farber Cancer Institute, Boston, MA
¹⁹Hematopathology Division, Department of Pathology, University of Rochester Medical Center, Rochester, NY
²⁰Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
²¹University of California, San Diego, La Jolla, CA
²²Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
²³Sidney Kimmel CCC, Johns Hopkins University, Baltimore, MD
²⁴Leukemia Service, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
²⁵Section of Hematology, Yale Univ. School of Medicine, New Haven, CT
²⁶Harvard Medical School, Boston, MA
²⁷Halia Therapeutics, Lehi, UT
²⁸Hematopathology, MD Anderson Cancer Center, Houston, TX
²⁹The University of Chicago Medicine and Comprehensive Cancer Center, Chicago, IL
³⁰Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
³¹Weill Cornell Medicine and The New York Presbyterian Hospital, New York, NY
³²Dana Farber Institute, Boston, MA
³³Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
³⁴Dana-Farber Cancer Institute, Cambridge, MA
³⁵Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN
³⁶Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
³⁷Yale University, New Haven, CT
³⁸Department of Hematology and Oncology, Moffitt Cancer Center, Tampa, FL
³⁹H. Lee Moffitt Cancer Center, Tampa, FL
⁴⁰University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL
⁴¹Laboratory of Myeloid Malignancies, Hematology Branch, National Heart, Lung, and Blood Institute, Bethesda, MD
⁴²Peter Maccallum Cancer Centre, Melbourne, VIC, Australia
⁴³University of Bologna, Bologna, Italy
⁴⁴Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
⁴⁵CIBERONC, Instituto de Salud Carlos III, Valencia, Spain
⁴⁶Gruppo Italiano Malattie Ematologiche Dell’Adulto GIMEMA, Rome, Rome, Italy
⁴⁷Division of Cancer Prevention, National Cancer Institute, Rockville, MD
⁴⁸Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN
⁴⁹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵⁰University of Texas MD Anderson Cancer Center, Houston, TX
⁵¹Hospital Clínic Barcelona, Barcelona, Spain
⁵²Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), Cytometry Service (NUCLEUS) and Department of Medicine, University of Salamanca, Salamanca, Spain
⁵³Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵⁴University of New Mexico, Albuquerque, NM
⁵⁵Department of Hematology, Oncology and Clinical Immunology, Universitatsklinik Dusseldorf, Dusseldorf, Germany
⁵⁶MLL Munich Leukemia Laboratory, Munich, Germany
⁵⁷Hospital A Beneficência Portuguesa de São Paulo, Sao Paulo, SP, Brazil
⁵⁸Japan Adult Leukemia Study Group, Tokyo, Japan
⁵⁹Sanatorio Sagrado Corazón, Buenos Aires, Argentina
⁶⁰Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, ENG, United Kingdom
⁶¹Nice University Hospital, Nice, Provence Alpes Cote d'Azur, France
⁶²King's College London, London, United Kingdom
⁶³Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
⁶⁴Saint Louis Hospital, APHP, Paris, France
⁶⁵Section of Hematology, Department of Internal Medicine, Yale University School of Medicine - Yale Cancer Center, New Haven, CT

Johann-Christoph Jann, MD^1,2*, Christopher B. Hergott, MD, PhD^1,3*, Marisa Winkler, MD^1,4*, Yiwen Liu^1*, Benjamin Braun^1*, Anne Charles^1*, Kevin Copson^1*, Shougat Barua^1*, Manja Meggendorfer, PhD⁵, Niroshan Nadarajah^5*, Shai Shimony, MD^6*, Eric S. Winer, MD¹, Martha Wadleigh, MD¹, Richard M Stone, MD¹, Daniel J. DeAngelo¹, Jacqueline S. Garcia, MD¹, Torsten Haferlach, MD, PhD⁵, Coleman Lindsley, MD, PhD¹, Marlise R. Luskin, MD, MSCE¹, Maximilian Stahl, MD⁷ and Zuzana Tothova, MD, PhD^1,8

¹Dana-Farber Cancer Institute, Boston, MA
²Broad Institute, Cambridge, MA
³Brigham and Women’s Hospital, Boston, MA
⁴Emory University, Atlanta
⁵MLL Munich Leukemia Laboratory, Munich, Germany
⁶Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁷Dana Farber Institute, Boston, MA
⁸Cancer Program, Broad Institute, Cambridge, MA

Rurika Okuda, MSc, BS^1*, Yotaro Ochi, MD, PhD^1*, Ryunosuke Saiki^1*, Nobuhiro Hiramoto^2*, Masashi Sanada, MD^1,3, Hiroshi Handa⁴, Senji Kasahara, MD, PhD^5*, Shinya Sato, MD^6*, Nobuhiro Kanemura, MD, PhD⁷, Toshiyuki Kitano, MD, PhD^8*, Mizuki Watanabe, MD, PhD^9*, Wolfgang Kern, MD¹⁰, Maria Creignou, MD^11*, Yuichi Shiraishi^12*, Mitsumasa Watanabe, MD, PhD¹³, Kensuke Usuki, MD, PhD¹⁴, Shinsaku Imashuku^15*, Eva Hellstrom Lindberg, MD, PhD^16*, Torsten Haferlach, MD, PhD¹⁰, Shigeru Chiba^17*, Nobuo Sezaki^18*, Lee-Yung Shih¹⁹, Yasushi Miyazaki, MD PhD⁶, Takayuki Ishikawa, MD², Kazuma Ohyashiki, MD, PhD^20*, Yoshiko Atsuta, MD, PhD^21*, Yusuke Shiozawa, MD^22*, Satoru Miyano, PhD^12,23*, Koichi Matsuda^24*, Hideki Makishima, MD, PhD¹, Yasuhito Nannya, MD, PhD¹ and Seishi Ogawa^16,25,26

¹Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
²Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan
³Department of Advanced Diagnosis, Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, JPN
⁴Department of Hematology, Gunma University Hospital, Maebashi, Gunma, Japan
⁵Department of Hematology, Gifu Municipal Hospital, Gifu, Japan
⁶Japan Adult Leukemia Study Group, Tokyo, Japan
⁷Department of Hematology and Infectious Disease, Gifu University Hospital, Gifu, Japan
⁸Deptartment of Hematology., Kitano Hospital, Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan
⁹Department of Hematology and Oncology, Kyoto University, Shinjukuku, TKY, JPN
¹⁰MLL Munich Leukemia Laboratory, Munich, Germany
¹¹Phase 1 Unit, Center for Clinical Cancer Studies, Karolinska University Hospital, Stockholm, Sweden
¹²Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
¹³Department of Hematology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan
¹⁴NTT Medical Center Tokyo, Tokyo, Japan
¹⁵Uji-Tokushukai Medical Center, Uji, JPN
¹⁶Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden
¹⁷Department of Hematology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan
¹⁸Department of Hematology, Chugoku Central Hospital, Hiroshima, Japan
¹⁹Chang Gung Memorial Hospital, Taipei, TWN
²⁰Tokyo Medical University, Tokyo, JPN
²¹Japanese Data Center For Hematopoietic Cell Transplantation, Nagakute, Japan
²²Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto City, JPN
²³Laboratory of DNA Information Analysis, The University of Tokyo, Tokyo, Japan
²⁴Department of Computational Biology and Medical Sciences, The University of Tokyo, Tokyo, JPN
²⁵Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan
²⁶Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Sakyoku, KYO, Japan

Julia Montoro^1*, Laura Palomo^2*, Claudia Haferlach, MD³, Pamela Acha^4*, Onyee Chan, MD^5*, Victor Navarro Garces^6*, Yasuo Kubota, MD, PhD^7*, Felicitas Schulz^8*, Manja Meggendorfer, PhD⁹, Robert Briski, MD^10*, Najla H Al Ali, MS^5*, Blanca Xicoy, PhD^11*, Felix Lopez, MD^12*, Pablo Vidal^13*, Francesc Bosch, MD, PhD^1*, Teresa González, PhD^14*, Lea Naomi Eder^15*, Andres Jerez, MD, PhD^16,17*, Hwei-Fang Tien, MD, PhD¹⁸, Valeria Santini¹⁹, Teresa Bernal Del Castillo, MD, PhD^20*, Esperanza Such, PhD^21*, Yu-Hung Wang, MD^22,23*, Anne Sophie Kubasch^24*, Uwe Platzbecker, MD²⁵, Detlef Haase, MD, PhD^26*, Maria Diez-Campelo, MD, PhD^27*, Matteo Giovanni Della Porta, MD^28*, Guillermo Garcia-Manero, MD¹⁰, Daniel H Wiseman, MBBChir, FRCPath, MRCP, PhD^29*, Ulrich Germing^30*, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP³¹, Rami S. Komrokji, MD⁵, Francesc Sole^11*, Torsten Haferlach, MD, PhD⁹ and David Valcarcel^1*

¹Department of Hematology, University Hospital Vall d’Hebron, Barcelona, Spain
²Experimental Hematology Unit, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
³MLL Munich Leukemia Laboratory, Inning am Ammersee, Germany
⁴Myelodysplastic Syndromes Research Group, Josep Carreras Leukaemia Research Institute, Badalona, Barcelona, Spain
⁵Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁶Oncology Data Science (ODysSey) Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
⁷Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Beachwood, OH
⁸Department of Hematology, University Hospital of Düsseldorf, Düsseldorf, Germany
⁹MLL Munich Leukemia Laboratory, Munich, Germany
¹⁰Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹¹Institut de Recerca Contra la Leucèmia Josep Carreras, Badalona, Spain
¹²Department of Hematology, Hospital del Mar, Barcelona, Spain
¹³Spanish Group of Myelodysplastic Syndromes (GESMD), Spain, Spain
¹⁴University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Department of Hematology - Hospital Universitario de Salamanca, Salamanca, Spain
¹⁵Clinics of Hematology and Medical Oncology, University Medical Center Göttingen, Georg-August- University, Göttingen, Germany
¹⁶Hematology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain
¹⁷Hospital Morales Meseguer, Murcia, Murcia, ESP
¹⁸Department of Internal Medicine, Far-Eastern Memorial Hospital, New Taipei, Taiwan
¹⁹MDS Unit, Hematology, University of Florence, AOUC, Florence, Italy
²⁰Servicio de Hematología, Hospital Universitario Central de Asturias Instituto de Investigación del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias, (IUOPA), Oviedo, Spain
²¹Department of Hematology, Hospital Universitari i Politecnic La Fe, Valencia, Spain
²²Department of Internal Medicine, Fra-Eastern Memorial Hospital, Taipei, Taiwan
²³Division of Cancer Sciences, The University of Manchester, Manchester, United Kingdom
²⁴Department of Hematology, University Hospital of Leipzig, Dresden, Germany
²⁵Department of Hematology, University Hospital of Leipzig, Leipzig, Germany
²⁶Clinics of Hematology and Medical Oncology, University Medical Center Göttingen, Georg-August- University, Goettingen, Germany
²⁷Department of Hematology, Salamanca-IBSAL University Hospital, Salamanca, Spain
²⁸Humanitas Clinical and Research Center – IRCCS, Milan, Italy
²⁹Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom
³⁰Department of Hematology, Oncology and Clinical Immunology, Universitatsklinik Dusseldorf, Dusseldorf, Germany
³¹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Tariq Kewan, MBBChir¹, Jan Philipp Bewersdorf, MD², Ondrej Blaha, PhD^3*, Maximilian Stahl, MD⁴, Najla H Al Ali, MS^5*, Amy E. DeZern, MD, MHS⁶, Mikkael A. Sekeres, MD⁷, Hetty E. Carraway, MD, MBA⁸, Pinkal Desai, MD, MPH⁹, Elizabeth A. Griffiths, MD¹⁰, Eytan M. Stein¹¹, Andrew M. Brunner, MD¹², Maria L Amaya, MD, PhD¹³, Joshua F. Zeidner, MD¹⁴, Michael R. Savona, MD¹⁵, Jessica M. Stempel, MD¹⁶, Namrata Sonia Chandhok, MD¹⁷, Hunter Cochran, MD¹⁸, Rahul Ramaswamy^19*, Abhay Singh, MD, MPH²⁰, Gail J. Roboz, MD²¹, Benjamin Rolles, MD²², Eunice S. Wang, MD²³, Amyah C. Harris^24*, Rory M. Shallis, MD²⁵, Zhuoer Xie, MD, MS²⁶, Eric Padron, MD⁵, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP²⁷, Matteo Giovanni Della Porta, MD^28*, Rami S. Komrokji, MD⁵, David A Sallman, MD²⁹ and Amer M. Zeidan, MBBS, MHS¹⁶

¹Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, New Haven, CT
²Memorial Sloan Kettering Cancer Center, New York, NY
³Yale Cancer Center, Yale University, New Haven
⁴Dana Farber Institute, Boston, MA
⁵Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁶Sidney Kimmel CCC, Johns Hopkins University, Baltimore, MD
⁷Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
⁸Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
⁹Weill Cornell Medicine, The New York Presbyterian Hospital, New York, NY
¹⁰Leukemia Service, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
¹¹Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹²Division of Hematology/Oncology, Dana-Farber Cancer Institute, Boston, MA
¹³Division of Hematology, University of Colorado, Aurora, CO
¹⁴University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC
¹⁵Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN
¹⁶Section of Hematology, Department of Internal Medicine, Yale University School of Medicine - Yale Cancer Center, New Haven, CT
¹⁷University of Miami, Miami, FL
¹⁸Washington University in St. Louis, Saint Louis, MO
¹⁹Washington University, Saint Louis
²⁰Taussig cancer center, Cleveland Clinic, Cleveland Clinic, Cleveland, OH
²¹Weill Cornell Medicine and The New York Presbyterian Hospital, New York, NY
²²Division of Hematology, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA
²³Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
²⁴Dana Farber Cancer Institute, Boston, MA
²⁵Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, Killingworth, CT
²⁶H. Lee Moffitt Cancer Institute, Tampa, FL
²⁷Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²⁸Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy
²⁹H. Lee Moffitt Cancer Center, Tampa, FL