Martina Sarchi, MD, PhD^1,2*, Courtnee A. Clough, PhD^1,3, Edie I. Crosse, PhD^4,5*, Jason Kim^1*, Laura D. Baquero Galvis^1,3, Anna Gallì^6*, J. Philip Creamer, PhD^1*, Sintra Stewart^1*, Sara Pozzi^2*, Elisabetta Molteni, PhD^6*, Chiara Elena, MD^6*, Robert K. Bradley, PhD^4,5,7, Luca Malcovati, MD^6,8 and Sergei Doulatov, PhD^1,7,9

¹Division of Hematology, Department of Medicine, University of Washington, Seattle, WA
²Department of Molecular Medicine, University of Pavia, Pavia, Italy
³Molecular and Cellular Biology Program, University of Washington, Seattle
⁴Computational Biology Program, Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA
⁵Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA
⁶Department of Hematology, IRCCS S. Matteo Hospital Foundation, Pavia, Italy
⁷Department of Genome Sciences, University of Washington, Seattle, WA
⁸Department of Molecular Medicine, University of Pavia, Piazzale Golgi 2, Italy
⁹Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA

Noah A Salama^1*, Emily R Quarato, MS^1*, Olivia Lynch, BA, MPH^1*, Yuko Kawano, MD, PhD^2*, Chen Yu, MS^1*, Benjamin Rodems, MS^3*, Eric Cefaloni^1*, Marlies P. Rossmann, MD, PhD⁴, Paula Vertino, PhD, BS^1*, Laurie A. Steiner, MD⁵, Kathleen E. McGrath, PhD¹, James Palis, MD¹, Roman Eliseev, MD/PhD^1*, Jane L. Liesveld, MD⁶, Jeevisha Bajaj, PhD² and Laura Calvi, MD¹

¹University of Rochester, Rochester, NY
²University of Rochester Medical Center, Rochester, NY
³University of Rochester Medical Center, Rochester
⁴Department of Biomedical Genetics, University of Rochester School of Medicine and Dentistry, Rochester, NY
⁵Center for Pediatric Biomedical Research, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY
⁶James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY

Daniel Chang, BSc^1*, Klara E Noble-Orcutt, BS, MS^2*, Wendy Hudson^1*, Aishwarya Iyer, BSc, MSc^3*, Emily Pomeroy, MS^1*, Craig E. Eckfeldt, MD, PhD⁴, Aaron Sarver, PhD^1*, Nuri Alpay Temiz, PhD^1*, Michael Linden, MD, PhD⁴, Chad L Myers, PhD^5,6*, David A. Largaespada, PhD^1* and Zohar Sachs, MD, PhD^2,7

¹University of Minnesota, Minneapolis, MN
²Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN
³University of Alberta, Edmonton, AB, CAN
⁴University of Minnesota Medical School, Minneapolis, MN
⁵Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN
⁶Bioinformatics and Computational Biology Program, University of Minnesota, Minneapolis, MN
⁷Masonic Cancer Center, University of Minnesota, Minneapolis, MN

Carmelo Gurnari, MD^1,2, Hideki Makishima, MD, PhD³, Arda Durmaz^1*, Ryunosuke Saiki^3*, Guilherme Mendes Sapinho^4,5*, Alex Bataller, MD, PhD^6*, Lukasz P. Gondek, MD, PhD⁷, Yasuhito Nannya^3*, Steve Best^4*, Pramila Krishnamurthy^4*, Hussein Awada^1*, Enrico Attardi, MD^2*, Valeria Visconte, PhD^1*, Maria Teresa Voso, MD², Amy E. DeZern, MD, MHS⁸, Guillermo Garcia-Manero, MD⁶, Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP⁹, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP¹ and Seishi Ogawa¹⁰

¹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
³Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
⁴Department of Haematological Medicine, King's College Hospital NHS, London, United Kingdom
⁵Serviço de Hematologia e Transplantação de Medula, Centro Hospitalar Lisboa Norte, Lisbon, Portugal
⁶The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, Johns Hopkins University, Baltimore, MD
⁸Johns Hopkins University, Baltimore, MD
⁹Department of Haematological Medicine, King's College Hospital, London, United Kingdom
¹⁰Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Sakyoku, KYO, Japan

He Tian (Tony) Tony Chen, BSc^1,2, Pratik Joshi, BSc^3,4*, Emily Tsao, BSc^3,4, Joshua Xu, BSc⁵, Soheil Jahangiri, PhD^4*, Yulin Mo, MSc^2*, David Kealy, PhD^6*, Dylan Gowlett-Park^7,8*, Katarina Czibere, BSc^7,8*, Alexandra Misura, BSc^7,8*, Olga Bigun, MD^7,8*, Renato Sasso^7,8*, Dianne Chadwick, PhD^8,9*, Sila Usta, BSc^7,8*, Tina Khazaee, MEng, MSc^7,8*, Signy Chow, MD^10,11, Hubert Tsui, MD, PhD, FRCPC^7,8,12,13, Mark D. Minden^3,4*, Katherine S Bridge, PhD, BSc^6*, Gang Zheng, PhD^2,3* and Kristin J. Hope^3,4

¹Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
²University Health Network, Toronto, ON, Canada
³Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
⁴Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁵Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, CAN
⁶Department of Biology, University of York, York, GBR
⁷Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
⁸Precision Diagnostics and Therapeutics Program, Department of Laboratory Medicine and Molecular Diagnostics, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
⁹Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, Canada
¹⁰Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
¹¹Temerty Faculty of Medicine, University of Toronto, Toronto, ON, CAN
¹²Department of Immunology, University of Toronto, Toronto, Canada
¹³Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

Srinivas Aluri, PhD^1*, Ellen Fraint¹, Samarpana Chakraborty¹, Aarif Ahsan^2*, Gowri Poigailwar^1*, Rongbao Zhao, PhD^3*, Kith Pradhan, PhD^3*, Kimo Bachiashvili¹, Anjali Budhathoki^1*, Beamon Agarwal^4*, Shanisha Gordon Mitchell^3*, Milagros Carbajal^1*, Srabani Sahu^3*, Jacqueline Boultwood, PhD^5*, Andrea Pellagatti^6*, Ulrich Steidl, MD, PhD¹, Amittha Wickrema^7*, Satish Nandakumar¹, Aditi Shastri, MD¹, Teresa Bowman¹, Sadanand Vodala⁸ and Amit K. Verma, MD¹

¹Department of Oncology, Albert Einstein College of Medicine, New York, NY
²Formerly Translational Medicine, Bristol Myers Squibb, Summit, NJ
³Montefiore Einstein Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
⁴GenomeRx, Barrington, IL
⁵Bloodwise Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
⁶University of Oxford, Oxford, United Kingdom
⁷University of Chicago, Chicago, IL
⁸Hematology, Translational Medicine and Disease Team, Bristol Myers Squibb, Summit, NJ