-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

626.O2.6 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Novel Therapies For Relapsed/Refractory Aggressive Lymphoma

Symposia: Aggressive Lymphomas: Prospective Therapeutic Trials Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, clinical trials, Biological therapies, Lymphomas, non-Hodgkin lymphoma, Bispecific Antibody Therapy, Non-Biological therapies, Clinical Research, B Cell lymphoma, Chemotherapy, Checkpoint Inhibitor, drug development, Diseases, aggressive lymphoma, Therapies, therapy sequence, Lymphoid Malignancies
Sunday, December 10, 2023: 9:30 AM-11:00 AM
Seaport Ballroom ABCD (Manchester Grand Hyatt San Diego)
Moderators:
Eliza A Hawkes, MD, Austin Health and Reem Karmali, Northwestern University Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center
Disclosures:
No relevant conflicts of interest to declare.
9:30 AM

Martin Hutchings, MD PhD1*, Carmelo Carlo-Stella, Prof MD2, Franck Morschhauser, MD PhD3, Lorenzo Falchi, MD4, Emmanuel Bachy, MD, PhD5*, Guillaume Cartron, MD, Ph-D6*, Cyrus Khan, MD7*, Monica Tani8*, Joaquin Martinez-Lopez, MD, PhD9*, Nancy L. Bartlett, MD10, Antonio Salar, MD11*, Joshua Brody, MD12*, Sirpa Leppä, MD, PhD13*, Pauline Baumlin, PharmD14*, Estefania Mulvihill, PhD14*, James Relf, MD15*, Yuying Xie, PhD16*, Derrick Kaufman, PhD17*, Linda Lundberg, PhD14* and Michael Dickinson, MBBS, D. Med Sci, FRACP, FRCPA18

1Rigshospitalet and University of Copenhagen, Copenhagen, Denmark
2Humanitas University and IRCCS Humanitas Research Hospital, Milan, Italy
3Hôpital Claude Huriez and CHU de Lille, Lille, France
4Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
5Centre Hospitalier Lyon-Sud, Lyon, France
6CHU de Montpellier, Montpellier, France
7Allegheny Health Network, Pittsburgh, PA
8Ospedale Santa Maria delle Croci, Ravenna, Italy
9Department of Hematology, Hospital Universitario 12 de Octubre, Spanish National Cancer Research Center (CNIO), Complutense University Madrid, Madrid, Spain
10Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO
11Department of Hematology, Hospital del Mar, Passeig Maritim, Barcelona, Spain
12Tisch Cancer Institute, New York, NY
13University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
14F. Hoffmann-La Roche Ltd, Basel, Switzerland
15Roche Products Ltd, Welwyn Garden City, United Kingdom
16F. Hoffmann-La Roche Ltd, Mississauga, ON, Canada
17Genentech, Inc., South San Francisco, CA
18Peter MacCallum Cancer Centre, Royal Melbourne Hospital and The University of Melbourne, Melbourne, VIC, Australia

9:45 AM

Christopher Melani, MD1, Rahul Lakhotia, MBBS1, Stefania Pittaluga, MD, PhD2*, James D Phelan, PhD1*, Da Wei Huang1*, George Wright3*, Jillian Simard, MD1*, Jagan R. Muppidi, MD, PhD1*, Craig J. Thomas, PhD4*, Michele Ceribelli, PhD4*, Frances A Tosto5*, Yandan Yang1*, Weihong Xu1*, Theresa Davies-Hill6*, Svetlana Pack6*, Cody J Peer7*, Oluwatobi Arisa7*, Esther Mena, MD8*, Maria L. Lindenberg, MD8*, Ethan Bergvall8*, Craig A. Portell, MD9, Rafic J Farah, MD10, Seung Tae Lee, MD11, Amynah Pradhan, NP1*, Candis Morrison, NP, PhD1*, Atekelt Tadese, PA1*, Anna M Juanitez, RN1*, Crystal Lu, PharmD12*, Allison P. Jacob, MSc13, Heidi Simmons, PhD14, William D Figg7*, Seth M. Steinberg, PhD15*, Elaine S Jaffe, MD2, Mark Roschewski, MD1, Louis M. Staudt, MD, PhD1 and Wyndham H Wilson, MD, PhD1*

1Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
2Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD
3Biometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD
4Division of Pre-Clinical Innovation Chemistry Technologies, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD
5Division of Pre-Clinical Innovation Chemistry Technologies, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD
6Laboratory of Pathology, Clinical Center, National Cancer Institute, National Institutes of Health, Bethesda, MD
7Clinical Pharmacology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
8Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
9Division of Hematology and Oncology, Department of Medicine, University of Virginia Medical Center, Charlottesville, VA
10Mario Lemieux Center for Blood Cancers, University of Pittsburgh School of Medicine, Pittsburgh, PA
11University of Maryland, Baltimore, MD
12Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD
13Medical Affairs, Adaptive Biotechnologies, Seattle, WA
14Adaptive Biotechnologies, Seattle, WA
15Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD

10:00 AM

Gerhard Held, MD1*, Bettina Altmann, PhD2*, Andrea Kerkhoff, MD3*, Thomas Gastinne, MD4*, Thomas Weber5*, Rene-Olivier Casasnovas, MD6*, Hervé Tilly, MD, PhD7, Maria Gomes Da Silva8*, Jörg Hoffmann9*, Sanne Tonino10*, Stéphane Vigouroux11*, Martin Dreyling, MD12, Violaine Safar, MD13*, Marc Andre, MD14*, Stephanie Mayer15*, Franck Morschhauser, MD PhD16, Pierre Feugier17*, Christian W. Scholz18, Anna Dabrowska-Iwanicka, MD19*, Philippe Gaulard, MD20*, Thierry Jo Molina, MD, PhD21*, Andreas Rosenwald, MD22*, Richard Greil, MD23, Ulrich Jaeger, MD24*, Abraham Avigdor, MD25, Lorenz Thurner, MD26, Stephanie Maurer, MSc26*, Markus Löffler2*, Marita Ziepert, PhD2*, Corinne Haioun, MD, PhD27, Viola Poeschel, MD28* and Roch Houot, MD, PhD29*

1Department of Internal Medicine 1, Westpfalz-Klinikum, Kaiserslautern, Germany
2Institut für Medizinische Informatik, Statistik und Epidemiologie, Universität Leipzig, Leipzig, Germany
3Medical Department A for Hematology, Oncology, and Pneumology, University Hospital Muenster, Muenster, Germany
4CHU Hôtel Dieu - Service d'Hématologie Clinique, Nantes, France
5Universitätsklinikum Halle an der Saale, Halle, DEU
6CHU DE DIJON - HÔPITAL F. MITTERRAND, Dijon, FRA
7Centre Henri-Becquerel and University of Rouen, Rouen, France
8Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, PRT
9Universitätsklinikum Gießen und Marburg (UKGM), Marburg, Germany
10AMC Academisch Medisch Centrum, Amsterdam, NLD
11Centre Hospitalier Départemental - Service d'Onco-Hématologie, La Roche Sur Yon Cedex 9, FRA
12Department of Medicine, Medical Clinic III, Ludwig-Maximilians-University Hospital, Munich, Germany
13Hematology, CHLS, CHU Lyon, Pierre Bénite, France
14Department of Hematology, Clinique de Mont-Godinne, Yvoir, Belgium
15Universitätsklinikum Regensburg, Regensburg, DEU
16Hôpital Claude Huriez Univ. Lille, CHU Lille, Lille, France
17CHU Brabois - Service d'Hématologie, Nancy, France
18Vivantes Klinikum am Urban, Berlin, DEU
19Maria Sklodowska-Curie Memorial Cancer Center, Warshaw, Poland
20Hôpital Henri Mondor, Créteil, France
21Necker enfants malades, APHP, Paris, Paris, France
22Institute of Pathology, Julius-Maximilians-Universität Würzburg, Wuerzburg, Germany
23Paracelsus Medical University, Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute - Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Salzburg, Austria
24Universitätsklinik für Innere Medizin I, AKH Wien, Wien, Austria
25Division of Hematology and Bone Marrow Transplantation, The Chaim Sheba Medical Center, Ramat Gan, Israel
26Department of Internal Medicine 1, Oncology, Hematology, Clinical Immunology, and Rheumatology, Saarland University Medical Center, Homburg/Saar, Germany
27Lymphoid Malignancies Department, Henri Mondor University Hospital, AP-HP, Créteil, France
28Department of Internal Medicine 1, Oncology, Hematology, Clinical Immunology, and Rheumatology, Saarland University Medical School, Homburg/Saar, Germany
29Clinical Hematology, INSERM U1236, EFS, Hopital Pontchaillou, Rennes University Hospital, Rennes, France

10:15 AM

Sabarish Ayyappan1*, Won Seog Kim, MD, MPH, PhD2*, Tae Min Kim, MD, PhD3*, Jan Walewski4*, Seok-Goo Cho5*, Isidro Jarque6*, Elzbieta Iskierka-Jazdzewska7*, Michelle Poon8*, Sung Yong Oh, MD9*, Francesca Lorraine Wei Inng Lim10*, Cecilia Carpio11*, Tran-Der Tan12, Antonio Gutiérrez13*, Huilai Zhang14*, Junning Cao15, Mingzhi Zhang16*, Benoit Tessoulin17*, Jingjin Li18*, Melanie Ufkin18, Saleem Shariff19*, Lei Chi18*, Aafia Chaudhry18, Hesham Mohamed18, Srikanth Ambati18* and H. Miles Prince20*

1University of Iowa Hospital and Clinics, Iowa City, IA
2Samsung Medical Center, Center for Hematologic Malignancy, Seoul, Korea, Republic of (South)
3Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South)
4Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Państwowy Instytut Badawczy, Warszawa, Poland
5Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of (South)
6Hospital Universitario La Fe, Valencia, Spain
7Copernicus Memorial Hospital, Medical University of Łódź, Łódź, Poland
8Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore
9Dong-A University Hospital, Busan, Korea, Republic of (South)
10Department of Hematology, Singapore General Hospital, Singapore, Singapore
11University Hospital Vall d'Hebron, Autonomous University of Barcelona (UAB), Barcelona, Spain
12Koo Foundation Sun Yat Sen Cancer Center, Taipei City, Taiwan
13Hospital Universitari Son Espases, IdISBa Palma, Palma de Mallorca, Spain
14Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
15Fudan University Shanghai Cancer Center, Shanghai, China
16The First Affiliated Hospital of Zhengzhou University and Lymphoma Diagnosis and Treatment Center of Henan Province, Zhengzhou, Henan, China
17Nantes University School of Medicine & University Hospital, Nantes, France
18Regeneron Pharmaceuticals, Inc., Tarrytown, NY
19Regeneron UK Ltd., Uxbridge, NY, United Kingdom
20Epworth Healthcare and University of Melbourne, Melbourne, VIC, Australia

10:30 AM

Charalambos Andreadis, MD1, Olivia Bobek, MS2*, Eric D. Hsi, MD3, Timothy S. Fenske, MD4*, Susan M. Geyer, PhD2, Patrick J. Stiff, MD5, Brian T. Hill, MD6, Mitchell Horwitz, MD7, Farhad Khimani, MBBS8*, Richard F. Little, MD, MPH9, Shira N. Dinner, MD10, Jonathan W. Friedberg, MD, MMSc11, Brad S. Kahl, MD12, Miguel-Angel Perales, MD13, Steven M. Devine, MD14, John P. Leonard15 and Nancy L. Bartlett, MD16

1Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA
2Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN
3Department of Pathology, Wake Forest Baptist Medical Center, Winston Salem, NC
4Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
5Division of Hematology and Oncology, Loyola University Medical Center, Maywood, IL
6Blood and Marrow Transplant Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
7Adult Stem Cell Transplant Program, Division of Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC
8Department of Blood and Marrow Transplantation and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL
9Division of Cancer Prevention, National Cancer Institute, Washington, DC
10Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
11Wilmot Cancer Center, University of Rochester, Rochester, NY
12Washington University School of Medicine in St. Louis, Saint Louis, MO
13Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
14Be the Match Foundation, Minneapolis, MN
15Weill Cornell Medicine, New York, NY
16Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO

10:45 AM

Irit Avivi Mazza, MD1*, Won Seog Kim, MD, MPH, PhD2*, Po-Shen Ko, MD3*, Carlos Grande, MD, PhD4*, David Lavie5*, David Chism, MD, MS6*, Mostafa Seliem, PharmD7*, Edwin E. Jeng, PhD7*, Neha Joshi, PhD7*, Satya Siddani, PhD7*, Wissam Assaily, PhD8*, Mariana Sacchi, MD9*, Minh Dinh, MD7* and Abraham Avigdor, MD10

1Hematology Division, Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
2Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University, Seoul, Korea, Republic of (South)
3Division of Hematology, Taipei Veterans General Hospital Division of Hematology, Taipei City, Taiwan
4Clínica Universidad de Navarra, Madrid, Spain
5Department of Hematology, Hadassah Medical Center, Jerusalem, Israel
6Thompson Cancer Survival Center, Knoxville, TN
7AbbVie, North Chicago, IL
8AbbVie Inc., North Chicago, IL
9Genmab, Plainsboro, NJ
10Sheba Medical Center, Ramat Gan and Tel Aviv University, Tel Aviv, Israel

*signifies non-member of ASH