-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

621.O2.6 621. Lymphomas: Translational – Molecular and Genetic: Microenvironment and Methylome in Lymphoma and Misc.

Symposia: Lymphomas: Translational—Molecular and Genetic Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, clinical trials, Translational Research, Lymphomas, non-Hodgkin lymphoma, assays, Clinical Research, bioinformatics, Diseases, Lymphoid Malignancies, Technology and Procedures, profiling, molecular testing
Saturday, December 9, 2023: 2:00 PM-3:30 PM
Ballroom 20AB (San Diego Convention Center)
Moderators:
Colm Keane, MD, ARRAY(0x10004504) and Wendy Beguelin, PhD, Weill Cornell Medicine
Disclosures:
Keane: Bristol Myers Squibb: Research Funding; AstraZeneca: Speakers Bureau; Beigene: Consultancy; Janssen: Consultancy; Gilead: Membership on an entity's Board of Directors or advisory committees; Roche: Consultancy, Membership on an entity's Board of Directors or advisory committees; Takeda: Speakers Bureau; MSD: Membership on an entity's Board of Directors or advisory committees, Research Funding; Karyopharm: Consultancy.
2:00 PM

Fabrice Jardin, MD PhD1*, Vibha Raghavan, MSc2*, Samuel Tracy, PhD3*, Sandhya Balasubramanian, MS4*, Laurie H. Sehn, MD, MPH5, Christopher R. Flowers, MD, MS6, Franck Morschhauser, phd7, Alex F. Herrera, MD8, Marek Trněný, MD9, Jeff P. Sharman, MD10, Gilles Salles, MD, PhD11, Hervé Tilly, MD, PhD1, Jonathan W. Friedberg, MD, MMSc12, Will Harris, MS3*, Jamie H. Hirata, PharmD13*, Calvin Lee, MD3, Yanwen Jiang, PhD3* and Georg Lenz14

1Centre Henri-Becquerel and University of Rouen, Rouen, France
2Hoffmann-La Roche Ltd, Mississauga, ON, Canada
3Genentech, Inc., South San Francisco, CA
4Genentech Inc., South San Francisco, CA
5BC Cancer Centre for Lymphoid Cancer and The University of British Columbia, Vancouver, BC, Canada
6Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
7University of Lille, Lille, France
8City of Hope, Duarte, CA
9Charles University General Hospital, Prague, Czech Republic
10Willamette Valley Cancer Institute and Research Center, Eugene, OR
11Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
12University of Rochester, Rochester, NY
13Genentech, South San Francisco, CA
14University of Münster, Munster, Germany

2:15 PM

Alexis Claudel1*, Anne Ségolène Cottereau, MD2*, Emmanuel Bachy, MD, PhD3*, Pierre Feugier4*, Rene-Olivier Casasnovas, MD5*, Corinne Haioun, MD, PhD6, Herve Tilly, MD7, Nicolas Daguindau8*, Guillaume Cartron, MD, Ph-D9*, Emmanuelle Nicolas Virelizier, MD10*, Pauline Brice11*, Benoit Tessoulin12*, Christophe Fruchart13*, Sylvie Glaisner14*, Alain Jacques Delmer, MD15*, Emmanuel Fleck16*, Gian Matteo Pica, MD17*, Hacene Zerazhi, MD18*, Stephanie Guidez19*, Morgane Cheminant20*, Luc Xerri, MD, PhD21*, Laetitia Vercellino, MD, PhD22*, Loïc Chartier23*, Lucie Gomes24*, Pierre-Julien Viailly24*, Marie-Helene Delfau, MD PhD25* and Franck Morschhauser, MD PhD26

1Hemato-biology, Henri Mondor University Hospital, CRETEIL, France
2Nuclear Medicine Department, Hopital Cochin, Paris, France
3Lyon-Sud Hospital Center, Pierre-Bénite, France
4Henri Poincaré University, Vandoeuvre Les Nancy, FRA
5CHU DE DIJON - HÔPITAL F. MITTERRAND, Dijon, FRA
6Lymphoid Malignancies Department, Henri Mondor University Hospital, AP-HP, Créteil, France
7Centre Henri-Becquerel, Rouen, France
8Hematologie, Centre Hospitalier Annecy Genevois, Metz-Tessy, FRA
9Centre Hospitalier Universitaire de Montpellier, Montpellier, France
10Hematology Department, Centre Léon Bérard, Lyon, FRA
11Hematology Department, Hopital Saint Louis, Paris, FRA
12Hematology Department, CHU Nantes, Nantes, France
13Hématologie, Centre hospitalier de Dunkerque, Dunkerque, FRA
14Hématologie - Centre René Huguenin, Institut Curie, ST CLOUD, FRA
15Hôpital Robert Debré CHU de Reims, Reims Cedex, -, FRA
16Centre Hospitalier de La Rochelle, LA ROCHELLE, FRA
17Hematology department, CH Chambery, Chambery, France
18Oncologie Médicale et Hématologie clinique, CH d'Avignon - Hôpital Henri Duffaut, Avignon, France
19Hematolgy department, University Hospital of Poitiers, Poitiers, France
20Department of Hematology, Necker Hospital, APHP, Paris, France
21Pathology Department, Institut Paoli Calmettes, Marseille, FRA
22Nuclear Medicine Department, Hopital Saint Louis, Paris, France
23LYSARC, Pierre Bénite, France
24INSERM U918, Centre Henri Becquerel, Rouen, France
25Hemato-biology, Henri Mondor University Hospital, Créteil, France
26Hematology Department, Centre Hospitalier Régional Universitaire de Lille, Lille, AL, France

2:30 PM

Bence Bátai1*, Ákos Nagy, MD1*, Tibor Nagy, PhD1,2*, Gábor Bedics, MD1*, Bence Gálik, PhD3*, Luca Varga, MSc1*, Péter Attila Király, MD, PhD4*, András Masszi, MD, PhD4, Gábor Mikala, MD, PhD5*, Péter Farkas, MD6*, Tamás Masszi, MD, PhD6*, Judit Demeter, MD, PhD7*, Ádám Jóna, MD, PhD8*, Piroska Pettendi, MD9*, Attila Gyenesei, PhD3*, Erika Tóth, MD, PhD10*, Botond Timár, MD, PhD1*, Judit Csomor, MD11*, András Matolcsy, MD, PhD11*, Tamás Schneider, MD, PhD4*, Donát Alpár, PhD1* and Csaba Bödör, PhD1*

1HCEMM-SU Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
2Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
3Szentágothai Research Centre, University of Pécs, Pécs, Hungary
4Department of Hematology and Lymphoma Care, National Institute of Oncology, Budapest, Hungary
5South-Pest Central Hospital, National Institute for Hematology and Infectious Diseases, Budapest, Hungary
6Department of Internal Medicine and Hematology, Semmelweis University, Budapest, Hungary
7Department of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary
8Department of Internal Medicine, University of Debrecen, Debrecen, Hungary
9Department of Internal Medicine, Jász-Nagykun-Szolnok County Hetényi Géza Hospital, Szolnok, Hungary
10Department of Surgical and Molecular Pathology, National Institute of Oncology, Budapest, Hungary
11Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary

2:45 PM

Tomohiro Aoki, MD, PhD1,2, Gerben Duns, PhD3*, Shinya Rai, MD, PhD3*, Andrew Lytle, MD, PhD3, Yifan Yin3*, Clementine Sarkozy4*, Stacy Hung, PhD3*, Katy Milne5*, Adele Telenius, MPhil, BSc6*, Luke O`Brien7*, Celia Strong8*, Talia Goodyear8*, Shaocheng Wu2*, Katsuyoshi Takata, MD, PhD9*, Tomoko Miyata-Takata2*, Merrill Boyle, BSc10*, Susana Ben-Neriah2*, Andrew P. Weng, MD2*, Andrew Roth, PhD2*, Anca Prica, MD, MSc11*, Robert Kridel11, Brad Nelson12*, Pedro Farinha, MD, PhD3, Kerry J. Savage, MD, MSc, BSc13, David W. Scott, MBChB, PhD3 and Christian Steidl, MD, PhD6

1Princess Margaret Cancer Centre, Toronto, ON, Canada
2BC Cancer, Vancouver, Canada
3BC Cancer, Vancouver, BC, Canada
4Hematology departement, institut Curie, Paris, France
5Deeley Research Centre, BC Cancer, Victoria, BC, CAN
6Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
7BC Cancer, Centre for Lymphoid Cancer, Vancouver, BC, Canada
8Deeley Research Centre, BC Cancer, Victoria, Canada
9Division of Molecular and Cellular Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
10Centre for Lymphoid Cancer, British Columbia Cancer, Vancouver, BC, Canada
11Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre - University Health Network, Toronto, Canada
12University of Victoria, Victoria, Canada
13Division of Medical Oncology, BC Cancer, Vancouver, BC, Canada

3:00 PM

Julia Paczkowska, PhD1*, Ming Tang, PhD2,3*, Kyle T. Wright, MD, PhD1,4,5*, Li Song, PhD2,6*, Kelsey Luu, MBI2,7*, Vignesh Shanmugam, MD5,8, Emma L. Welsh, BE5,9*, Jason L. Weirather, PhD2*, Kathleen Pfaff, PhD5,9*, Robert A. Redd, MS2*, Zumla Cader, MBChB, PhD1,10*, Elisa Mandato, PhD1*, Jing Ouyang, PhD1,11*, Gali Bai, MS2,12*, Lee N. Lawton, PhD1*, Philippe Armand, MD, PhD1, Scott Rodig, MD, PhD5,9, Xiaole Shirley Liu, PhD2,13,14* and Margaret A. Shipp, MD1

1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
2Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
3Immunitas Therapeutics, Waltham, MA
4Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
5Department of Pathology, Brigham and Women's Hospital, Boston, MA
6Department of Biomedical Data Science, Dartmouth College, Hanover, NH
7PathAI, Boston, MA
8Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA
9Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA
10Hematology, Oncology R&D, AstraZeneca, Cambridge, United Kingdom
11Mechanism of Cancer Resistance Thematic Center, Bristol Myers Squibb, Cambridge, MA
12Department of Biomolecular Engineering in the Baskin School of Engineering, University of California Santa Cruz, Santa Cruz, CA
13Harvard T.H. Chan School of Public Health, Boston, MA
14GV20 Therapeutics, LLC, Cambridge, MA

3:15 PM

Kyoko Yamaguchi, BSc1*, Salma Abdelbaky2*, Evgeny Arons, PhD3*, Matthew Cross, MBBS, BSc4*, Yue-Zhong Wu5*, Christoph Weigel, PhD1, Mirela Iulia Anghelina, MD, MPH6*, Helen Parker7*, Artur Kibler8*, Marta Salido, PhD9*, Constance Regina Baer, PhD10, Manja Meggendorfer, PhD10, Benjamin Durham, MD, PhD11*, Omar Abdel-Wahab, MD11, Seema A Bhat, MD2, Gerard Lozanski, MD12*, Kerry A Rogers, MD2, Yonghong Wang13*, Paul S. Meltzer, MD, PhD14*, Sunil Iyengar, MBBS, PhD, MRCP15, Sascha Dietrich, MD16*, Thorsten Zenz17, James S. Blachly18, Aurelie Verney19*, Lucile Baseggio20*, Alexandra Traverse-Glehen, MD, PhD21*, Marc Seifert22*, Ralf Kuppers, PhD23*, Richard Burack, MD, PhD24, Clive S Zent, MD25, Versha Banerji, MD26,27, James B. Johnston, MB28, David Graham Oscier, MD, PhD29, Renata Walewska, MD, PhD30*, Kostas Stamatopoulos31, Torsten Haferlach, MD, PhD10, Ana Ferrer, MD, PhD32*, Catherine Thieblemont, MD33,34*, Francesco Forconi, MD, PhD, DM, FRCPath7*, Robert J. Kreitman, MD35, Michael R. Grever, MD2, Jonathan C. Strefford, BSc36, Piers Blombery, MBBS37 and Christopher C. Oakes, PhD38

1Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
2Division of Hematology, The Ohio State University, Columbus, OH
3Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD
4Royal Marsden Hospital, Sutton, ENG, GBR
5The Ohio State University, Columbus, OH
6The Ohio State University, Columbus
7School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
8Institute of Cellbiology, Essen, DEU
9Laboratori de Citogenètica, Servei de Patologia, Hospital del Mar, GRETNHE, IMIM, Barcelona, Spain
10MLL Munich Leukemia Laboratory, Munich, Germany
11Memorial Sloan Kettering Cancer Center, New York, NY
12Department of Pathology, The Ohio State University, Columbus, OH
13National Institute of Health, Bethesda, MD
14NCHGR, NIH, Bethesda, MD
15Royal Marsden Hospital, London, GBR
16Heidelberg University Hospital, Heidelberg, DEU
17University of Zurich (UZH), Zurich, Switzerland
18Department of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH
19UCBL, Oullins Cedex, FRA
20Department of Hematologic Laboratory, Hospices Civils De Lyon/GHS, Pierre Benite, FRA
21Department of Pathology, Lyon Sud Hospital, Pierre Benite, France
22Institute For Cellbiology, Essen, DEU
23University of Duisburg-Essen, Essen, DEU
24Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY
25Wilmot Cancer Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY
26Paul Albrechtsen Research Institute, Univeristy of Manitoba and CancerCare Manitoba, Winnipeg, MB, Canada
27Departments of Internal Medicine, Biochemistry & Medical Genetics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba and CancerCare Manitoba, Winnepeg, Canada
28Cancer Care Manitoba, Winnipeg, MB, CAN
29Division of Haematology, University Hospitals Dorset, Bournemouth, United Kingdom
30Molecular Pathology, University Hospitals Dorset, Bournemouth, United Kingdom
31Institute of Applied Biosciences, Centre for Research and Technology Hellas, Asvestohori, Greece
32Laboratori de Citologia Hematològica, Servei de Patologia, Hospital del Mar, GRETNHE, IMIM, Barcelona, Spain
33Assistance Publique & Hôpitaux de Paris (APHP), Hôpital Saint-Louis, Hémato-oncologie, Université de Paris, Paris, France
34Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Hemato-oncologie, Université de Paris, Paris, France
35National Institutes of Health, Bethesda, MD
36School of Cancer Sciences, Faculty of Medicine, Univ. of Southampton, Southampton, United Kingdom
37Peter Maccallum Cancer Centre, East Melbourne, VIC, Australia
38Division of Hematology, Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH

*signifies non-member of ASH