-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

615.O3.6 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Long-Term Outcomes for Children and Adults Diagnosed With AML/APL

Symposia: Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, clinical trials, Clinical Research, real-world evidence
Monday, December 11, 2023: 10:30 AM-12:00 PM
Room 6A (San Diego Convention Center)
Anna Candoni, Professor, MD, Section of Haematology, Dept. of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena and Eric S. Winer, MD, Dana Farber Cancer Institute
Candoni: Pfizer: Consultancy; Astellas: Honoraria; Janssen: Honoraria; Incyte: Consultancy, Honoraria; Abbvie: Consultancy, Honoraria. Winer: Curis Inc: Consultancy; Abbvie: Consultancy.
The focus of this session will be on the long term (and real world) outcomes for children and adults treated for acute myeloid leukemia and acute promyelocytic leukemia. Reports on long term outcomes after intensive chemotherapy as well as bone marrow transplant and maintenance therapy will be presented.
10:30 AM

Luca Guarnera, MD1,2*, Soren Lehmann, MD, PhD3*, Konstanze Döhner4, Hartmut Döhner, MD4, Uwe Platzbecker, MD5, Nigel H. Russell, MD6, Richard Dillon, PhD, MRCP, FRCPath7*, Ian Thomas8*, Gert Ossenkoppele, MD, PhD9, Marco Vignetti, MD10*, Edoardo la Sala, MSc11*, Alfonso Piciocchi, MS12*, Angela Villaverde Ramiro13*, Laura Tur14*, Carmelo Gurnari, MD1,2, Lars Bullinger15, Jesús María Hernández-Rivas, PhD16 and Maria Teresa Voso, MD2,17

1Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
2Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
3Department of Medical Sciences, Hematology, Uppsala University, University Hospital Uppsala, Uppsala, Sweden
4Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
5Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases, University Leipzig Medical Center, Leipzig, Germany
6Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
7Guy’s Hospital and King’s College, London, United Kingdom
8Cardiff University, Cardiff, United Kingdom
9Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
10GIMEMA Foundation, Rome, Italy
11GIMEMA Foundation, Data Center and Health Outcomes Research Unit, Roma, ITA
12GIMEMA Foundation, Data Center and Health Outcomes Research Unit, Rome, Italy
13University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Department of Hematology - Hospital Universitario de Salamanca, Salamanca, Spain
14GMV Innovating Solutions, Valencia, Spain
15Department of Hematology, Oncology, and Cancer Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany
16Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain
17Neuro-Oncohematology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy

10:45 AM

Franco Locatelli, MD, PhD1, Barbara Buldini, MD, PhD2, Martina Pigazzi, PhD3*, Carmelo Rizzari, MD4*, Rosanna Cuccurullo, MD5*, Franca Fagioli, MD6*, Manuela Tumino, MD7*, Luca Lo Nigro, MD8, Maria Giuseppina Cefalo, MD9*, Luisa Strocchio, MD10*, Marco Zecca, MD11*, Marco Becilli, MD12*, Andrea Pession, MD13*, Nicola Santoro, MD14*, Concetta Micalizzi, MD15*, Riccardo Masetti, MD16* and Pietro Merli, MD17*

1Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children’s Hospital, Catholic University of the Sacred Heart, Rome, Italy
2Department of Pediatric Hematology and Oncology, University of Padova, Padua, Italy
3Department of Women's and Children's Health, Onco-hematology lab and clinic, University of Padova, Padova, Italy
4Universita Di Milano, Monza, ITA
5Pediatric Hemato Oncology, Pausillipon Hospital, Naples, Italy
6Ospedale Infantile Regina Margherita and University of Turin, Turin, Italy
7University of Padova, Padova, AL, ITA
8Azienda Policlinico OVE - Center of Pediatric Hematology Oncology, Catania, Italy, Italy
9Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children Hospital (IRCCS), Rome, Italy
10Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children Hospital (IRCCS), Rome, ITA
11Pediatric Hematology-Oncology,, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
12Department of Haematology-Oncology and Cell and Gene Therapy, Bambino Gesù Children Hospital, Rome, Italy
13Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ITA
14Department of Pediatric Hemato-Oncology, University of Bari, Bari, Italy
15IRCCS Istituto Giannina Gaslini, Department of Paediatric Haematology and Oncology, Genova, Italy
16Pediatric Oncology and Hematology Unit "lalla Seràgnoli," Department of P, Bologna, ITA
17Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children Hospital (IRCCS), Rome, Italy

11:00 AM

Li Gao1*, Xiuli Ju, MD PhD2*, Hua Jiang, MD PhD3*, Ning Liao, MD4*, Ningling Wang, MD5*, Xiaowen Zhai, MD PhD6*, Chun Li7*, Yufeng Liu, MD PhD8*, Qi An, MD PhD9*, Jixia Luo, MD10*, Minghua Yang, MD PhD11*, Liangchun Yang, MD PhD12*, Xiaojun Yuan, MD PhD13*, Qianfei Wang, PhD14*, Yi Wang1*, Hailong He1*, Jun Lu1*, Peifang Xiao1*, Raul C. Ribeiro, MD15 and Shaoyan Hu, MD, PhD1

1Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou, China
2Department of Hematology and Oncology, Qilu Hospital of Shandong University, Qingdao, China
3Department of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, China
4Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
5Department of Hematology and Oncology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China
6Department of Hematology and Oncology, Children's Hospital of Fudan University, Shanghai, China
7Department of Hematology and Oncology, Anhui Provincial Hospital, Hefei, China
8Department of Hematology and Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
9Department of Hematology and Oncology, Xuzhou Children's Hospital, Xuzhou, China
10Department of Hematology and Oncology, Kaifeng Children's Hospital, Kaifeng, China
11Department of Hematology and Oncology, The Third Xiangya Hospital of Central South University, Changsha, China
12Department of Pediatrics, Xiangya Hospital, Changsha, China
13Department of Pediatric Hematology/Oncology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
14CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China
15Division of Leukemia/Lymphoma, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

11:15 AM

Andrew Moore, MBBS, PhD, FRACP1*, Shanna Maycock, MSc2*, Guy Leverger, MD, PhD3*, Owen Smith, MD4*, Andre Baruchel, MD5, Yves Bertrand, MD6*, Phil Ancliff7*, Nicholas Heaney8*, Geoff Shenton9*, Arnaud Petit, MD, PhD10*, Jean-Pierre Bourquin, MD, PhD11, Aimee Jackson, MSc2*, Anna Lawson, BSc2*, Persis Amrolia, FRCP, FRCPath, PhD12*, Gerard Michel, MD13*, Jean-Hugues Dalle14*, Marc Ansari, MD, PhD15, Hélène Lapillonne, MD, PhD3*, Richard Dillon, PhD, MRCP, FRCPath16*, Jelena Jovanovic, PhD17*, Christophe Roumier, PharmD18*, Nicolas Duployez, PharmD, PhD18*, Christine Harrison, PhD, FRCPath19*, Claire Schwab, PhD19*, Wendy Cuccuini, MD, PhD20*, Marina Lafage-Pochitaloff, MD, PhD21*, Paresh Vyas, FMedSci, DPhil, FRCPath22*, Pierre Hirsch, MD, PhD23*, Gareth Veal, PhD19*, Pam Kearns, MBChB, PhD, FRCPC2* and Brenda Gibson, MD, PhD8*

1Queensland Children's Hospital, South Brisbane, QLD, Australia
2Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom
3Hôpital Trousseau, Paris, France
4Children's Health Ireland, Dublin, Ireland
5Hôpital Robert Debré, Paris, France
6Institut d'Hématologie et Oncologie Pédiatrique, Lyon, France
7Department of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom
8Royal Hospital for Children, Glasgow, Glasgow, United Kingdom
9Great North Children’s Hospital, Newcastle, United Kingdom
10Hôpital Armand Trousseau, APHP, Paris, France
11Department of Oncology and Children’s Research Center, University Children's Hospital Zurich, Zurich, Switzerland
12Great Ormond Street Children’s Hospital, London, United Kingdom
13Hôpital de la Timone, Marseille, France
14Department of Pediatric Hematology and Immunology, University Hospital Robert Debré, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
15Hôpital Universitaire de Genève, Switzerland, Geneve, Switzerland
16Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
17King’s College London, London, United Kingdom
18Hôpital Claude Huriez, Lille, France
19Newcastle University, Newcastle, United Kingdom
20Hôpital Saint-Louis, Paris, France
21CHU Timone Enfants, Marseille, France
22Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
23Hôpital Saint-Antoine, Paris, France

11:30 AM

Fabio Guolo, MD, PhD1,2*, Luana Fianchi, MD, PhD3*, Maria Paola Martelli, MD, PhD4*, Patrizia Chiusolo3*, Federico Lussana, MD, PhD5*, Francesco Grimaldi, MD6*, Federica Pilo, MD7*, Michela Rondoni8*, Carla Fili, MD9*, Debora Capelli, MD10*, Massimo Breccia11*, Sara Mastaglio, MD12*, Monica Bocchia, MD13*, Monica Fumagalli, MD14*, Sara Galimberti, MD, PhD15*, Valentina Mancini, MD16*, Anna Lina Piccioni, MD17*, Luca Maurillo, MD18*, Raffaele Palmieri, MD18*, Andrea Corbingi, MD19*, Calogero Vetro, MD20*, Alessandra Sperotto, MD21*, Federica Gigli, MD22*, Patrizia Zappasodi, MD23*, Antonio Mulé, MD24*, Erika Borlenghi, MD25*, Michelina Dargenio, MD26*, Federica Lessi, MD27*, Marco Cerrano, MD28*, Alessandro Isidori, MD, PhD29, Lorenzo Brunetti, MD30*, Cristina Papayannidis, MD31, Monia Lunghi, MD, PhD32*, Caterina Alati, MD33*, Samuele Gatani34*, Francesco Mannelli, MD35*, Nicola Fracchiolla, MD36*, Michele Gottardi, MD21*, Roberto Cairoli, MD37*, Felicetto Ferrara, MD38*, Roberto Massimo Lemoli, MD39,40*, Adriano Venditti, MD41, Livio Pagano, MD3* and Elisabetta Todisco, MD34*

1IRCCS Ospedale Policlinico San Martino, Genoa, Italy
2Clinic of Hematology, Department of Internal Medicine (DiMI), University of Genoa, Genoa, Italy
3Dipartimento di Scienze Radiologiche Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy
4Dipartimento di Medicina e Chirurgia, Hematology, Department of Medicine and Surgey, University of Perugia and "Santa Maria della Misericordia" Hospital, Perugia, ITA
5Department of Oncology-Hematology, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
6Department of Clinical Medicine and Surgery, Hematology Unit, University of Naples Federico II, Naples, ITA
7SC di Ematologia e CTMO,, Ospedale Oncologico di Riferimento Regionale "A. Businco", ARNAS "G. Brotzu", Cagliari, Italy
8Hematology Unit & Metropolitan Transplant Network, AUSL Romagna, Ravenna, Italy
9Division of Hematology and Stem Cell Transplantation, University Hospital ASUF, Udine, Italy
10Clinica di Ematologia, Azienda Ospedaliero-Universitaria delle Marche, Ospedali Riuniti di Ancona, Ancona, ITA
11Department of Translational and Precision Medicine, Hematology-Sapienza University, Rome, Italy
12Hematology and Bone Marrow Transplant, Unit San Raffaele Scientific Institute, Milan, Italy
13UOC Ematologia, Azienda ospedaliero-universitaria Senese, Siena, Italy
14Hematology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
15Department of Clinical and Experimental Medicine, Hematology, University of Pisa, Pisa, Italy
16Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy
17Dipartimento di Ematologia, Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy
18Department of Onco-Hematology, Fondazione Policlinico Tor Vergata, Rome, Italy
19Hematology, Polo Universitario Pontino, "Sapienza", S.M. Goretti Hospital, Latina, Italy
20Division of hematology, A.O.U. Policlinico G.Rodolico – S. Marco, Catania, Italy
21Onco Hematology, Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Castelfranco Veneto, Italy
22Divisione di Oncoematologia, European Institute of Oncology, Milan, Italy
23Clinica Ematologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
24Division of Hematology 1, Azienda Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy
25Hematology, ASST Spedali Civili, Brescia, Italy
26Divisione di Ematologia e Centro Trapianti, CSE Vito Lazzi, Lecce, Italy
27Divisione di Ematologia e Centro Trapianti, Azienda Ospedaliera Universitaria di Padova, Padova, Italy
28Division of Hematology, Department of Oncology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy
29Hematology and Stem Cell Transplant Center, AORMN Hospital, Pesaro, Italy
30Clinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy
31Istituto di Ematologia "Seràgnoli", IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy
32Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
33U.O.C. Ematologia, Grande Ospedale Metropolitano Bianchi Melacrino Morelli, Reggio Calabria, Italy
34Hematology Department, ASST Valle Olona, Varese, Italy
35CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
36Hematology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milano, Italy
37Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
38Divisione di Ematologia, Ospedale Cardarelli, Napoli, Italy
39Clinic of Hematology, Department of Internal medicine (DiMI), University of Genoa, Genoa, Italy
40Clinica Ematologica, Dipartimento di Oncologia e Ematologia, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
41Department of Onco-Hematology, Fondazione Policlinico Tor Vergata, Rome, Italy, Italy

11:45 AM

Malin S. Nilsson1*, Anna Martner, PhD2*, Fredrik B. Thorén2* and Kristoffer Hellstrand, MD, PhD2*

1Institute of Biomedicine, Gothenburg, Sweden
2TIMM Laboratory at Sahlgrenska Center for Cancer Research, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden

*signifies non-member of ASH