-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

506.O1.6 506. Bone Marrow Microenvironment: Bone Marrow Microenvironment in Health and Disease

Symposia: Bone Marrow Microenvironment Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Fundamental Science, Acute Myeloid Malignancies, AML, MDS, Biological therapies, Translational Research, Bone Marrow Failure Syndromes, Chronic Myeloid Malignancies, drug development, Diseases, Therapies, Myeloid Malignancies, Transplantation
Sunday, December 10, 2023: 12:00 PM-1:30 PM
Room 11 (San Diego Convention Center)
Moderators:
Owen J. Tamplin, PhD, University of Wisconsin School of Medicine and Public Health and Pratibha Singh, PhD, Indiana University School of Medicine
Disclosures:
No relevant conflicts of interest to declare.
Selected abstracts focusing on the role of the bone marrow niche in HSC regulation and its impact in hematological malignancies will be discussed in a high-quality oral session.
12:00 PM

Shoichiro Takeishi, MD, PhD1,2, Tony Marchand, MD, PhD1,2,3,4*, Wade R. Koba, BS5*, Daniel K. Borger, BA1,2*, Chunliang Xu, PhD1,2,6*, Chandan Guha, MBBS, PhD7,8,9*, Aviv Bergman, PhD10,11,12*, Paul S. Frenette, MD1,2,13*, Kira Gritsman, MD, PhD1,2,14,15 and Ulrich Steidl, MD, PhD1,2,15,16,17

1Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY
2Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY
3Service d’Hématologie Clinique, Centre Hospitalier Universitaire de Rennes, Rennes, France
4INSERM U1236, Université Rennes 1, Rennes, France
5Department of Radiology, Albert Einstein College of Medicine, Bronx, NY
6Sun Yat-sen University, Guangzhou, Guangdong Province, China
7Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY
8Department of Pathology, Albert Einstein College of Medicine, Bronx, NY
9Department of Urology, Albert Einstein College of Medicine, Bronx, NY
10Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY
11Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY
12Santa Fe Institute, Santa Fe, NM
13Department of Medicine, Albert Einstein College of Medicine, Bronx, NY
14Department of Medical Oncology, Montefiore Medical Center, Bronx, NY
15Blood Cancer Institute, Albert Einstein College of Medicine, Bronx, NY
16Departments of Oncology and Medicine, Albert Einstein College of Medicine-Montefiore Health System, Bronx, NY
17Montefiore Einstein Cancer Center, Albert Einstein College of Medicine-Montefiore Health System, Bronx, NY

12:15 PM

Dinisha Kamble, PhD*, Nick Imperiale, MS* and Pratibha Singh, PhD

Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN

12:30 PM

Rheanna Grace Congdon, BS1*, Ji Zha, PhD, BS1, Xia Qin, MD, PhD2*, Lori Kunselman1,3* and Timothy S Olson, MD, PhD1,4,5,6,7,8

1Cell Therapy and Transplant Section, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
2Department of Hematology and Oncology, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
3Children's Hospital of Philadelphia, Philadelphia, PA
4Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
5Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA
6Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA
7Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
8Department of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA

12:45 PM

Irene Ganan-Gomez, PhD, MSc1*, Bijender Kumar, PhD2*, Juan Jose Rodriguez Sevilla1*, Feiyang Ma3*, Yi June Kim4*, Kelly S. Chien, MD4, Kate Nelson, Bs1*, Hui Yang, MD, PhD4*, Roselyn Tan5*, Zongrui Li1*, Tomoyuki Tanaka, MD, PhD1*, Hidetaka Uryu, MD, PhD1*, Rashmi Kanagal-Shamanna, MD6, Sanam Loghavi, MD6, Gheath Alatrash, PhD, DO7, Rafael Bejar, MD, PhD5, Katy Rezvani, MD7, Koichi Takahashi, MD, PhD4, Guillermo Garcia-Manero, MD8, May Daher, MD7 and Simona Colla, PhD9

1Leukemia, MD Anderson Cancer Center, Houston, TX
2Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
3University of Michigan, Ann Arbor, MI
4Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
5University of California, San Diego, La Jolla, CA
6Hematopathology, MD Anderson Cancer Center, Houston, TX
7Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX
8University of Texas MD Anderson Cancer Center, Houston, TX
9MD Anderson Cancer Center, HOUSTON, TX

1:00 PM

Eman Khatib-Massalha, PhD1,2,3*, Ya-Hsuan Ho, PhD1,2,3*, Elodie Grockowiak, PhD1,2,3*, Yuki Date, PhD1,2,3*, Lam Tan Khuat, PhD1,2,3*, Zijian Fang, PhD1,2,3*, Eva Carrillo Félez, MSc1,2,3*, Christian Di Buduo, PhD4*, Alessandra Balduini, MD4,5 and Simón Méndez-Ferrer, PhD1,2,3*

1Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom
2Department of Hematology, University of Cambridge, Cambridge, United Kingdom
3NHS Blood and Transplant, Cambridge, United Kingdom
4University of Pavia, Pavia, ITA
5Tufts University, Medford, MA

1:15 PM

Charles E Ayemoba1,2*, Sen Zhang, PhD1*, Anna M Di Staulo1,2*, Thomas G Henderson3*, Mary Menhart3*, Alex M Dittmar1*, Konstantinos Chronis, PhD3* and Sandra Pinho, PhD1

1Department of Pharmacology & Regenerative Medicine, University of Illinois at Chicago, Chicago, IL
2University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL
3Department of Biochemistry & Molecular Genetics, University of Illinois at Chicago, Chicago, IL

*signifies non-member of ASH