-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

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Ticketed Session denotes that this is a ticketed session.

331.O1.6 331. Thrombotic Microangiopathies/Thrombocytopenias and COVID-19-Related Thrombotic/Vascular Disorders: Clinical and Epidemiological: New Frontiers in TTP: Diagnostic and Therapeutic Innovations

Symposia: Thrombotic Microangiopathies/Thrombocytopenias and COVID-19-related Thrombotic/Vascular Disorders: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, clinical trials, Bleeding and Clotting, epidemiology, Clinical Research, Genetic Disorders, Diseases, thrombocytopenias, thrombotic disorders, registries, survivorship
Monday, December 11, 2023: 10:30 AM-12:00 PM
Room 29 (San Diego Convention Center)
Pavan K Bendapudi, MD, Beth Israel Deaconess Medical Center and Radhika Gangaraju, MD, University Of Alabama
Bendapudi: Takeda Pharmaceuticals: Consultancy; Alexion Pharmaceuticals: Consultancy. Gangaraju: Sanofi Genzyme: Consultancy, Honoraria; Alexion: Consultancy; Takeda: Consultancy.
Oral abstracts in this session discuss population prevalence and recombinant ADAMTS13 for congenital TTP, provide insights into the kinetics of ADAMTS13 recovery in reponse to targeted therapies in immune TTP, and subclinical cardiac disease in immune TTP survivors.
10:30 AM

Marissa Schraner, PhD1,2, Erika Tarasco, PhD1,3*, Odile Stalder, MSc4*, Kenneth D. Friedman, MD5, James N. George, MD6, Ingrid Hrachovinova, PhD7*, Paul N. Knöbl, MD8*, Masanori Matsumoto9, Reinhard Schneppenheim, MD, PhD10, Anne-Sophie Von Krogh, MD11*, Zuzana Cermakova, MD12*, Magdalena Górska-Kosicka, MD13*, Kazuya Sakai, MD, PhD9*, György Sinkovits, MD, PhD14*, Yasmine El Chazli, MD15*, Carlo R. Largiadèr, PhD16*, Oleg Pikovsky, MD17, Jerzy Windyga, MD, PhD13, Bernhard Lämmle, MD18* and Johanna A. Kremer Hovinga, MD1,3

1Department of Hematology and Central Hematology Laboratory, Bern University Hospital, Bern, Switzerland
2Department for BioMedical Research (DBMR), University of Bern, 3008, Switzerland
3Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland
4CTU Bern, University of Bern, Bern, Switzerland
5Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI
6Department of Biostatistics & Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK
7NRL for Hemostasis, Institute of Hematology and Blood Transfusion, Prague, Czech Republic
8Division of Hematology and Hemostasis, Department of Medicine I, Medical University of Vienna, Vienna, Vienna, Austria
9Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Japan
10Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
11Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
12Blood Center, University Hospital Ostrava, Ostrava, Czech Republic
13Department of Hemostasis Disorders and Internal Medicine, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
14Department of Internal Medicine and Hematology, Semmelweis University - Eötvös Loránd Research Network (Office for Supported Research Groups), Budapest, Hungary
15Hematology/Oncology Unit, Department of Pediatrics, Faculty of Medicine, Alexandria University, Alexandria, Egypt
16University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, Bern, Bern, Switzerland
17Transfusion Medicine Institute, Soroka University Medical Center, Beer-Sheva, Israel
18Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany

10:45 AM

Marie Scully, MD1, Thomas L. Ortel, MD, PhD2, Ziqiang Yu3*, Maria Waliullah4*, Pinghai Zhang4*, Munjal Patel4*, Parth Patwari, MD, PhD4*, Bjorn Mellgard4 and Linda T. Wang4*

1Department of Haematology, University College London Hospitals, London, United Kingdom
2Division of Hematology, Department of Medicine, and Department of Pathology, Duke University, Durham, NC
3National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China
4Takeda Development Center Americas, Inc., Cambridge, MA

11:00 AM

Omid Seidizadeh, Msc, Phd1*, Andrea Cairo2*, Ilaria Mancini, PhD3*, Pasquale Agosti, MD, PhD4*, Frits Rosendaal, MD5* and Flora Peyvandi, Prof6

1Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
2Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, A. Bianchi Bonomi Hem, Milan, ITA
3Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milano, MI, ITA
4Università Degli Studi Di Milano, Department of Pathophysiology and Tran, Milan, ITA
5Leiden University Med. Center, Leiden, NLD
6Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

11:15 AM

Maryam Subhan1*, Nithya Prasannan, MBBS, FRCPath, MRCP2*, Bertina Dragunaite1*, Karen Vanhoorelbeke, PhD3, Marie Scully, MD4 and Mari Thomas, PhD2*

1University College London, London, United Kingdom
2University College London Hospital, London, United Kingdom
3Laboratory for Thrombosis Research, KU Leuven, Kortrijk, Belgium
4University College London, London, ENG, United Kingdom

11:30 AM

Kenki Saito1*, Kazuya Sakai1*, Masayuki Kubo1,2*, Hidekazu Azumi1*, Atsushi Hamamura1*, Shinichi Ochi3*, Shinya Kobayashi3*, Hideo Yagi3 and Masanori Matsumoto1,2

1Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Japan
2Department of Hematology, Nara Medical University, Kashihara, Japan
3Department of Hematology and Oncology, Nara Prefecture General Medical Center, Nara, Japan

11:45 AM

Senthil Sukumar, MD, MSc1, Leah Danish2*, Ang Li, MD, MS1, Yuchi Han, MD, MMSc3* and Spero Cataland, MD4

1Section of Hematology-Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX
2Ohio State University, Columbus, OH
3Division of Cardiovascular Disease, Department of Medicine, Ohio State University, Columbus, OH
4Division of Hematology, Department of Medicine, Ohio State University Comprehensive Cancer Center, Columbus, OH

*signifies non-member of ASH