Ahmad M Tarawah, MD^1*, Tarek M Owaidah, MD, FRCPA^2,3,4, Raghad A Tarawah, MD^5*, Saud Balelah, MD^6*, Mohammed A Zolaly^7*, Asim Abdullah Alamri, MD^8*, Waheed A Turkistani, MD^9*, Insherah Barnawi, MD^10*, Mohamed Hisham Fakher, MD^11* and Zakaria Al hawsawi, MD^12*

¹Madinah Hereditary Blood Disorders Centre, King Salman bin Abdulaziz Medical city, Madinah, Saudi Arabia
²National Blood and Cancer Center, Riyadh, Saudi Arabia
³alfaisal university, Riyadh, Saudi Arabia
⁴King Faisal Specialist Hosp. and Rsch. Ctr., AR Riyadh, AR Riyadh, Saudi Arabia
⁵Department of Medicine, King Fahad hospital, Madinah, Saudi Arabia
⁶King Salman bin Abdulaziz Medical City, Madinah, Saudi Arabia
⁷College of Medicine, Taibah University, Madinah, Saudi Arabia
⁸King Salman bin Abdulaziz Medical city, Madinah, Saudi Arabia
⁹King Salman bin Abdulaziz Medical City, Madinah, Saudi Arabia
¹⁰King Fahad hospital, Medina, Saudi Arabia
¹¹Regional blood bank, Madinah, Saudi Arabia
¹²Health care medical complex, Madinah, Saudi Arabia

David J Kuter, MD, DPhil¹, Imene Gouia, PharmD, MSc Health Economics^2*, Matias Cordoba, MD^3*, Brad Ward, PharmD^4*, Ines Hemim, PharmD, MSc Health Economics^5*, Duane Madziva, MPH^5* and Natalia Petruski-Ivleva, PhD, MS^5*

¹Hematology Division, Massachusetts General Hospital, Boston, MA
²Sanofi, Gentilly, France
³Sanofi, Cambridge, MA
⁴US Medical, Sanofi, Cambridge, MA
⁵HEVA, Sanofi, Cambridge, MA

Zain Virk, MD^1*, Rebecca Karp Leaf, MD², David J Kuter, MD, DPhil^3,4, Katayoon Goodarzi, MD^2*, Nathan T. Connell, MD, MPH^4,5, Jean M. Connors, MD⁶ and Hanny Al-Samkari, MD^4,7

¹Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
²Massachusetts General Hospital, Boston, MA
³Hematology Division, Massachusetts General Hospital, Boston, MA
⁴Harvard Medical School, Boston, MA
⁵Hematology Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA
⁶Dana-Farber Cancer Institute, Boston, MA
⁷Division of Hematology Oncology, Massachusetts General Hospital, Boston, MA

Elizabeth King, PharmD^1*, Uzo Abajue, PharmD^2*, Amanda Pawlenty, PharmD^2*, Huong Lan Truong, PharmD^2*, Sabrina Fischer, PharmD^3*, Alexandra P. Wolanskyj-Spinner, MD⁴, Rajiv K. Pruthi, M.B.B.S.⁵, Carl C. Hook, MD⁶, Animesh D. Pardanani, MBBS, PhD⁷, Aneel Ashrani, MBBS, MSc⁸, Ewa Wysokinska, MD⁹, Surbhi Shah, MD¹⁰ and Ronald S. Go, MD¹¹

¹Department of Pharmacy, Mayo Clinic - Rochester, Oronoco, MN
²Department of Pharmacy, Mayo Clinic - Rochester, Rochester, MN
³Department of Pharmacy, Mayo Clinic - Jacksonville, Jacksonville, FL
⁴Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
⁵Comprehensive Hemophilia Center and Special Coagulation Laboratory, Division of Hematopathology, Mayo Clinic, Rochester, MN
⁶Mayo Clinic, Rochester, MN
⁷Division of Hematology, Mayo Clinic, Rochester, MN
⁸Mayo Clinic College of Medicine, Rochester, MN
⁹Mayo Clinic, Jacksonville, FL
¹⁰Arizona, Mayo Clinic, Scottsdale, AZ
¹¹Mayo Clinic, Onalaska, WI

Anna Frandsen^1,2*, Nikolaj Mannering^2,3*, Dennis Lund Hansen^2,3*, Tarec Christoffer Christoffer El-Galaly, MD, DSc^2,3,4,5, Lasse Hjort Jakobsen, MSc, PhD^6* and Henrik Frederiksen, MD, PhD^2,3

¹Department of Clinical Research, University of Southern Denmark, Odense C, Denmark
²Department of Hematology, Odense University Hospital, Odense, Denmark
³Department of Clinical Research, University of Southern Denmark, Odense, Denmark
⁴Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
⁵Department of Medicine Solna, Clinical Epidemiology Division, Karolinska Institutet, Stockholm, Sweden
⁶Department of Hematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark

Anne Rudbeck Juhl, MD^1,2,3*, Andreas Glenthoej, MD, PhD^1,2, Boerge Groenne Nordestgaard, MD, DMSci^2,3,4*, Jesper Petersen, PhD^1*, Morten Dahl, MD, PhD, DMSci^2,5*, Christina Ellervik, MD, PhD, DMSci, MMSci^2,6,7,8*, Stig Egil Bojesen, MD, DMSci^2,3,4* and Jens Helby, MD, PhD^1,3*

¹Danish Red Blood Cell Center, Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
²Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
³The Copenhagen General Population Study, Copenhagen University Hospital – Herlev and Gentofte, Herlev, Denmark
⁴Department of Clinical Biochemistry, Copenhagen University Hospital – Herlev and Gentofte, Herlev, Denmark
⁵Department of Clinical Biochemistry, Zealand University Hospital, Koege, Denmark
⁶Department of Pathology, Harvard Medical School, Boston, MA
⁷Department of Production, Research, and Innovation, Region Zealand, Soroe, Denmark
⁸Department of Laboratory Medicine, Boston Children's Hospital, Boston, MA