Amy Barber, PhD^1*, John R Jones, MD^1,2*, Harvey Che^1*, Yann-Vai Le Bihan^1*, Niels Weinhold, PhD^3*, Cody Ashby, PhD^4*, Brian A Walker, PhD⁵, Christopher P. Wardell, PhD, MSc, BSc^6*, Hannah Wang, PhD^1*, Martin F. Kaiser, MD, FRCP, FRCPath^1,7, Graham H Jackson, MD, MA, MB BS, FRCP, FRCPath⁸, Faith E. Davies⁹, Rajesh Chopra, MD^1*, Gareth Morgan, MD, PhD⁹ and Charlotte Pawlyn, BA, PhD, MBBChir, MRCP, FRCPath^1,7

¹The Institute of Cancer Research, London, United Kingdom
²Kings College Hospital NHS Foundation Trust, London, United Kingdom
³Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany
⁴Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR
⁵Division of Hematology Oncology, Indiana University, Indianapolis, IN
⁶Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR
⁷The Royal Marsden NHS Foundation Trust, London, United Kingdom
⁸Department of Haematology, Newcastle University, Newcastle upon Tyne, United Kingdom
⁹Perlmutter Cancer Center, New York University Langone Health, New York, NY

Sherry Bhalla^1*, David Melnekoff, BS, MS^2*, Jonathan J Keats, PhD³, Kenan Onel, MD, PhD⁴, Deepu Madduri, MD⁵, Joshua Richter, M.D.^5*, Shambavi Richard, MD^5*, Ajai Chari, MD⁶, Hearn Jay Cho, MD, PhD^5,7, Joel Dudley, PhD^8*, Sundar Jagannath, MD^5,9, Alessandro Lagana, PhD^10* and Samir S. Parekh, MD⁵

¹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
³Translational Genomics Research Institute, Phoenix, AZ
⁴Icahn School of Medicine at Mount Sinai, New York, NY
⁵Department of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁶Department of Hematology and Medical Oncology, Tisch Cancer Institute, Mt. Sinai School of Medicine, New York, NY
⁷MMRF; Icahn School of Medicine at Mount Sinai, Norwalk, CT
⁸Tempus Labs, Inc, Chicago, IL
⁹Department of Hematology and Medical Oncology, Tisch Cancer Institute, Mount Sinai Medical Center, New York, NY
¹⁰Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York

Abdul Hamid Bazarbachi, MD^1*, Herve Avet-Loiseau², Zachary R Hunter, PhD³, Raphael Szalat⁴, Anil Aktas-Samur, PhD^5*, Masood A. Shammas, PhD^6*, Jill Corre, PharmD, PhD^7*, Mariateresa Fulciniti, PhD⁸, Kenneth Anderson, MD⁹, Giovanni Parmigiani, PhD^10*, Steven Treon¹¹, Mohamad Mohty, MD, PhD^12,13, Mehmet K. Samur, PhD¹⁴ and Nikhil C. Munshi, MD¹⁵

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Paris, France
²Insititut Universitaire du Cancer, Unite de Genomique du Myelome, IUC-Oncopole, Toulouse, France
³Bing Center for Waldenstrom's Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA
⁴Boston University School of Medicine, Boston, MA
⁵Department of Data Science, Dana Farber Cancer Institute, Boston, MA
⁶Dana-Farber Cancer Institute, Boston, MA
⁷Unite de Génomique du Myélome, IUC-T Oncopole, Toulouse, France
⁸Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁹The LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
¹⁰Data Science, Dana-Farber Cancer Institute, Boston, MA
¹¹Bing Center for Waldenstrom Macroglobulinemia, Dana-Farber Cancer Institute, Boston, MA
¹²Department of Haematology and EBMT Paris study office / CEREST-TC, Saint Antoine Hospital, INSERM UMR 938 and Université Pierre et Marie Curie, Paris, France
¹³Saint Antoine Hospital, Paris, France
¹⁴Department of Data Science, Dana-Farber Cancer Institute, Harvard TH Chan School of Public Health, Boston, MA
¹⁵Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

Marina Zajec^1*, Pieter Langerhorst^2*, Somayya Noori^1*, Martijn van Duijn^1*, Yolanda de Rijke^1*, Jolein Gloerich^2*, Alain van Gool^2*, Jill Corre, PharmD, PhD^3*, Thomas Dejoie^4*, Helene Caillon^5*, Joannes Jacobs^2*, Theo Luider^1* and Herve Avet-Loiseau⁶

¹Erasmus MC, Rotterdam, Netherlands
²Radboudumc, Nijmegen, Netherlands
³Unite de Génomique du Myélome, IUC-T Oncopole, Toulouse, France
⁴Biochemistry Laboratory, University Hospital, Nantes, France
⁵HOSPITAL OF NANTES, NANTES, FRA
⁶Unite de Genomique du Myelome, IUC-T Oncopole, Toulouse, France

Ye Yang, PhD¹, Chunyan Gu^2*, Wang Wang^3* and Xiaozhu Tang^3*

¹Nanjing University of Chinese Medicine, Nanjing, China
²Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China
³Nanjing University of Chinese Medicine, Nanjing, CHN

Connor S Murphy, BS^1,2*, Heather Fairfield, MS^1,3,4*, Mariah Farrell, BS^1,3,4*, Victoria DeMambro, MS^1,5*, Samantha Costa^1,5*, Carolyne Falank, PhD^1*, Calvin Vary^1,6* and Michaela Reagan, PhD^1,3,4

¹Maine Medical Center Research Institute, Scarborough, ME
²Graduate School of Biomedical Science and Engineering, University of Maine, Scarborough, ME
³University of Maine, Orono, ME
⁴Tufts University School of Medicine, Boston, MA
⁵Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME
⁶Cell, Molecular and Developmental Biology, Tufts School of Medicine, Boston, MA

Elizabeth Hill, MD¹, Neha Korde, MD², Candis Morrison, CNP, PhD^1*, Alexander Dew, DO, MS^1,3, Ashley Carpenter, RN^1*, Monica Epstein, RN^1*, Crystal Lu, PharmD, BCOP^4*, Peter Choyke, MD^5*, Esther Mena, MD^5*, Liza Lindenberg, MD^5*, Ola Landgren, MD, PhD² and Dickran Kazandjian, MD⁶

¹Center for Cancer Research, Lymphoid Malignancies Branch, Multiple Myeloma Program, National Cancer Institute, National Institutes of Health, Bethesda, MD
²Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
³Walter Reed Medical Center, North Bethesda, MD
⁴Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD
⁵Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁶Center for Cancer Research, Lymphoid Malignancies Branch, Multiple Myeloma Program, NIH, Potomac, MD

Bharat Nandakumar^1*, David L. Murray, MD, PhD^2*, Angela Dispenzieri, MD¹, Prashant Kapoor, MD³, Francis K. Buadi, MB, CHB^3*, Martha Q. Lacy, MD³, Morie Gertz³, David Dingli, MD, PhD³, Yi L. Hwa, NP¹, Amie Fonder, PA-C, MS^1*, Miriam A. Hobbs, APRN, CNP, DNP^1*, Suzanne R. Hayman, MD¹, John A. Lust, MD, PhD¹, Nelson Leung, MD³, Ronald S. Go, MD⁴, Yi Lin, MD, PhD¹, Wilson I Gonsalves, MD¹, Taxiarchis Kourelis, MD³, Rahma M Warsame, MD¹, Mustaqeem A. Siddiqui, MD, MBA¹, Robert A. Kyle, MD³, S. Vincent Rajkumar, MD³ and Shaji K. Kumar, MD³

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
³Mayo Clinic Rochester, Division of Hematology, Rochester, MN
⁴Mayo Clinic Rochester, Division of Hematology, Onalaska, WI

Cesarina Giallongo, PhD^1*, Grazia Scandura^2*, Alessandro Barbato^3*, Alessandra Romano, MD, PhD⁴, Fabrizio Puglisi^3*, Daniela Cambria^3*, Enrico La Spina^2*, Giuseppe Musumeci, Ph.D.^5*, Michelino Di Rosa, PhD^5*, Concetta Conticello^3*, Giovanni Li Volti, MD, PhD^6*, Giuseppe A. Palumbo, MD, PhD^7*, Francesco Di Raimondo, MD^8,9 and Daniele Tibullo, PhD^10*

¹Department of Medical and Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Catania, Italy
²Division of Hematology, University of Catania, Catania, Italy
³Division of Hematology, Azienda Policlinico - OVE, University of Catania, Catania, Italy
⁴CHIRMED - Department of General Surgery and Medical-Surgical Specialties - Hematology Section, University of Catania, Tremestieri Etneo, Cantania, Italy
⁵Section of Human Anatomy, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy
⁶Department of Biomedical and Biotechnological Sciences, Univeristy of Catania, Catania, Italy
⁷Department of Medical, Surgical and Advanced Technology "G.F. Ingrassia", University of Catania, Catania, Italy
⁸Division of Hematology, A.O.U. "Policlinico-Vittorio Emanuele", University of Catania, Catania, Italy
⁹Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy
¹⁰Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy

Ida Steiro^1*, Pegah Abdollahi, PhD^1*, Magne Børset, MD, Phd^1,2* and Tobias S. Slørdahl, MD, PhD^1,3*

¹Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
²Department of Immunology and Transfusion Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
³Department of Haematology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway

Reyka G Jayasinghe, PhD^1*, Lijun Yao^1*, Beena Thomas^2*, Swati S Bhasin, PhD^3*, Nicolas Fernandez, PhD^4*, David E. Avigan, MD², Taxiarchis Kourelis, MD⁵, Madhav V. Dhodapkar, MD⁶, Ravi Vij, MD, MBA⁷, Shaadi Mehr, PhD^8*, Mark Hamilton, PhD^9*, Hearn Jay Cho, MD, PhD¹⁰, Daniel Auclair¹¹, Sacha Gnjatic^12* and Li Ding, PhD^13*

¹Department of Medicine, Washington University School of Medicine, Saint Louis, MO
²Beth Israel Deaconess Medical Center, Boston, MA
³School of Medicine, Emory University, Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Atlanta, GA
⁴Human Immune Monitoring Center, Icahn School of Medicine at Mt. Sinai, New York, NY
⁵Mayo Clinic Rochester, Division of Hematology, Rochester, MN
⁶Emory University School of Medicine, Atlanta, GA
⁷Washington University School of Medicine, Ballwin, MO
⁸MMRF, New York, NY
⁹Multiple Myeloma Research Foundation, Norwalk, CT
¹⁰MMRF; Icahn School of Medicine at Mount Sinai, Norwalk, CT
¹¹Multiple Myeloma Research Foundation (MMRF), Norwalk, CT
¹²Mount Sinai School of Medicine, New York, NY
¹³Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO

Barry Rosenbloom, MD¹, Maria Domenica Cappellini², Marta Ofelia Dragosky, MD^3*, Neal J Weinreb, MD⁴, Monica McClain, MS^5*, Davorka Sekulic, BS^5* and Pramod K. Mistry, MD, PhD, FRCP^6,7*

¹Cedars-Sinai Medical Center, Beverly Hills, CA
²Foundation IRCCS Ca' Granda Policlinico Milano - University of Milan, Milano, MI, Italy
³Henry Moore Institute, Buenos Aires, Argentina
⁴University Research Foundation for Lysosomal Storage Diseases, Boca Raton, FL
⁵Sanofi-Genzyme, Cambridge, MA
⁶Yale University School of Medicine, New Haven, CT
⁷Yale University, New Haven, CT

Marcella Kaddoura, MD¹, David Dingli, MD, PhD², Francis K. Buadi, MB, CHB^2*, Martha Q. Lacy, MD², Morie A Gertz, MD³, Angela Dispenzieri, MD⁴, Prashant Kapoor, MD², Yi L. Hwa, NP³, Amie Fonder, PA-C, MS^3*, Miriam A. Hobbs, APRN, CNP, DNP^3*, Suzanne R. Hayman, MD³, John A. Lust, MD, PhD³, Nelson Leung, MD², Ronald S. Go, MD⁵, Yi Lin, MD, PhD³, Wilson I Gonsalves, MD², Taxiarchis Kourelis, MD², Rahma M Warsame, MD⁴, Robert A. Kyle, MD², Stephen Broski, MD^6*, S. Vincent Rajkumar, MD² and Shaji K. Kumar, MD²

¹Department of Hematology and Medical Oncology, Mayo Clinic, Rochester, MN
²Mayo Clinic Rochester, Division of Hematology, Rochester, MN
³Division of Hematology, Mayo Clinic, Rochester, MN
⁴Mayo Clinic, Rochester, MN
⁵Mayo Clinic Rochester, Division of Hematology, Onalaska, WI
⁶Radiology, Mayo Clinic, Rochester, MN

Filip Garbicz, MD^1,2*, Anna Szumera-Ciećkiewicz, MD, PhD^3*, Joanna Barankiewicz, MD^4*, Dorota Komar, PhD^2*, Michał Pawlak, PhD^2*, Sonia Dębek, MSc^1,2*, Aleksandra Matrejek, MSc^2*, Thorsten Stuehmer, PhD^5*, Aleksander Salomon-Perzynski, MD^4*, Agata Malenda, MD, PhD^4*, Krzysztof Brzózka, PhD⁶, Tomasz Rzymski, PhD^6*, Andrea Massimiliano Tomirotti, PhD^7*, Ewa Lech-Marańda, MD, PhD^4,8*, Monika Prochorec-Sobieszek, MD, PhD^3*, Maciej Szydlowski, PhD^2* and Przemyslaw Juszczynski, MD, PhD^2*

¹Postgraduate School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland
²Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
³Department of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
⁴Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
⁵Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg, Würzburg, Germany
⁶Ryvu Therapeutics S.A., Cracow, Poland
⁷Experimental and Translational Oncology Department, Menarini Ricerche S.p.A., Pomezia, Italy
⁸Department of Hematology and Transfusion Medicine, Centre of Postgraduate Medical Education, Warsaw, Poland

David Böckle^1,2*, Paula Tabares Gaviria^1,3*, Xiang Zhou, MD^1*, Janin Messerschmidt, MD^1*, Lukas Scheller^1*, Maximilian Johannes Steinhardt, MD^1*, Elena Seebacher^1,3*, Maria Ulbrich^1,3*, Anke Heidemeier, MD^4*, Andreas Buck, MD^5*, Hermann Einsele, MD¹, Andreas Beilhack, MD^1,3*, Martin Kortuem, MD^1* and Leo Rasche, MD^1*

¹Department of Internal Medicine II, Division of Oncology and Hematology, Würzburg University Hospital, Würzburg, Germany
²Department of Internal Medicine II, Division of Oncology and Hematology, Würzburg University Hospital, Germany, Würzburg, Germany
³Interdisciplinary Center for Clinical Research Laboratory, Würzburg University Hospital, Würzburg, Germany
⁴Department of Radiology, Würzburg University Hospital, Würzburg, Germany
⁵Department of Nuclear Medicine, Würzburg University Hospital, Würzburg, Germany

Tina Bagratuni, PhD^1*, Nefeli Mavrianou-Koutsoukou, BSc^2*, Dimitrios Patseas^3*, Christine Ivy Liacos, MSc^4*, Ioannis Ntanasis-Stathopoulos, MD^4*, Nikolaos Kanellias, MD^4*, Magdalini Migkou^2*, Evangelos Eleutherakis-Papaiakovou, MD^4*, Maria Roussou, MD^4*, Despina Fotiou, BMBS, MA^4*, Maria Gavriatopoulou^4*, Evangelos Terpos, MD, PhD⁴, Efstathios Kastritis, MD^5* and Meletios A. Dimopoulos, MD⁴

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Attiki, Greece
²National and Kapodistrian University of Athens, Athens, Greece
³NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS, ATHENS, Greece
⁴Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁵National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Tim Ellis-Caleo, MD^1*, Surbhi Sidana, MD², Michaela Liedtke, MD³ and David Iberri, MD³

¹Department of Medicine, Stanford University School of Medicine, Stanford, CA
²Division of Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA
³Division of Hematology, Stanford University School of Medicine, Stanford, CA

Yusuke Isshiki, MD, PhD^1,2, Naoya Mimura, MD, PhD^2,3, Motohiko Oshima, PhD^4*, Kensuke Kayamori, MD, PhD^2,4*, Masahide Seki, PhD^5*, Yurie Nagai, MD^2*, Tomoya Muto, MD, PhD², Shokichi Tsukamoto, MD, PhD², Yusuke Takeda, MD, PhD^2*, Chikako Ohwada, MD, PhD^2,6, Sonoko Misawa, MD, PhD^7*, Jun-ichiro Ikeda, MD, PhD^8*, Satoshi Kuwabara, MD, PhD^7*, Yutaka Suzuki, PhD^5*, Emiko Sakaida, MD, PhD^2*, Chiaki Nakaseko, MD, PhD^6* and Atsushi Iwama, MD, PhD⁴

¹Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY
²Department of Hematology, Chiba University Hospital, Chiba, Japan
³Department of Transfusion Medicine and Cell Therapy, Chiba University Hospital, Chiba, Japan
⁴Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
⁵Laboratory of Systems Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
⁶Department of Hematology, International University of Health and Welfare, Narita, Japan
⁷Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan
⁸Department of Diagnostic Pathology, Chiba University Graduate School of Medicine, Chiba, Japan

Jia Chen^1*, Xue-min Gao^1*, Hao Zhao, MD^1*, Hao Cai^1*, Lu Zhang, MD^1*, Xin-xin Cao, MD^1*, Dao-Bin Zhou^1* and Jian Li, MD^1,2

¹Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
²Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China

Elizabeth Hill, MD¹, Baris Turkbey, MD^2*, Evrim Turkbey, MD^3*, Candis Morrison, CNP, PhD^1*, Peter Choyke, MD^2*, Esther Mena, MD^2*, Liza Lindenberg, MD^2* and Dickran Kazandjian, MD⁴

¹Center for Cancer Research, Lymphoid Malignancies Branch, Multiple Myeloma Program, National Cancer Institute, National Institutes of Health, Bethesda, MD
²Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
³Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD
⁴Center for Cancer Research, Lymphoid Malignancies Branch, Multiple Myeloma Program, NIH, Potomac, MD

Sabrina L. Browning, MD¹, Terri L. Parker, MD¹, Noffar Bar, MD¹, Tara Anderson, PA^2*, Madhav V. Dhodapkar, MBBS³, Stuart Seropian, MD¹, Alfred Ian Lee, MD, PhD⁴, Thomas Prebet, MD, PhD¹, Stephanie Halene, MD ¹, Mina L. Xu, MD^5*, Elan Gorshein, DO, JD, MPH^1*, Ashita Talsania, MCRP, MBBS⁶, Wajih Zaheer Kidwai, MD⁷, David H. Witt, MD^8*, Victor Chang, MD^9*, Andrew Lischuk, MD^10*, Wei Wei, MD, PhD^11*, Andrew Haims, MD^10* and Natalia Neparidze, MD¹

¹Department of Internal Medicine, Section of Hematology, Yale University School of Medicine and Yale Cancer Center, New Haven, CT
²Yale-New Haven Hospital and Yale Cancer Center, New Haven, CT
³Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA
⁴Section of Hematology, Department of Internal Medicine, Yale University School of Medicine and Yale Cancer Center, New Haven, CT
⁵Department of Pathology and Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT
⁶Smilow Cancer Hospital Care Center- Torrington, Yale University School of Medicine and Yale Cancer Center, Torrington, CT
⁷Smilow Cancer Hospital Care Center- Guilford, Yale University School of Medicine and Yale Cancer Center, Guilford, CT
⁸Smilow Cancer Hospital Care Center- Trumbull, Yale University School of Medicine and Yale Cancer Center, Trumbull, CT
⁹Smilow Cancer Hospital Care Center-Waterbury, Yale University School of Medicine and Yale Cancer Center, Waterbury, CT
¹⁰Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT
¹¹Department of Biostatistics, Yale School of Public Health, New Haven, CT

Hiroyuki Takamatsu, MD, PhD¹, Naoki Takezako, MD, PhD², Takeshi Yoroidaka, MD^3*, Takeshi Yamashita, MD^4*, Ryoichi Murata, MD^4*, Atsuko Yamazaki, MD^5*, Masahiro Takeuchi, MD, PhD⁶, Naoya Mimura, MD, PhD⁷, Chiaki Nakaseko, MD, PhD^8*, Emiko Sakaida, MD, PhD⁹, Masahiro Onoda, MD^10*, Yoshikazu Utsu, MD, PhD^11*, Motoharu Fukazawa, MD^12*, Kosei Matsue, MD, PhD¹³ and Shinji Nakao, MD, PhD¹

¹Department of Hematology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan
²Department of Hematology, Disaster Medical Center of Japan, Tachikawa, Japan
³Department of Hematology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, ISH, Japan
⁴Department of Internal Medicine, Keiju Kanazawa Hospital, Kanazawa, Japan
⁵Department of Hematology, Oami Municipal Hospital, Oamishirasato, CHI, Japan
⁶Department of Hematology and Medical Oncology, Chiba Cancer Center, Chiba, Japan
⁷Department of Transfusion Medicine and Cell Therapy, Chiba University Hospital, Chiba, Japan
⁸Department of Hematology, International University of Health and Welfare, Narita, Japan
⁹Department of Hematology, Chiba University Hospital, Chiba City, Japan
¹⁰Department of Internal Medicine, Chiba Aoba Municipal Hospital, Chiba, Japan
¹¹Department of Hematology and Oncology, Japanese Red Cross Narita Hospital, Narita, Japan
¹²Department of Internal Medicine, JCHO Funabashi Central Hospital, Funabashi, Japan
¹³Division of Hematology/Oncology, Department of Medicine, Kameda General Hospital, Kamogawa, Japan

Martin H Van Vliet^1*, Yan-Ting Chen, PhD^2*, Erik H Van Beers, PhD^2*, Rowan Kuiper, PhD^2*, Erik T. Valent, PhD^2*, Marieke Spaan, MSc^2*, Carolina Terragna^3*, Elena Zamagni, MD^3*, Michele Cavo^3*, Stefania Oliva^4*, Alessandra Larocca⁵, Torsten Haferlach, MD⁶, Wee-Joo Chng, MBBS, PhD, FRCPath, FRCP⁷, Anders Waage, MD, PhD⁸, M Duin^9* and Pieter Sonneveld, MD, PhD⁹

¹SKYLINEDX, Rotterdam
²SkylineDx, Rotterdam, Netherlands
³Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
⁴Myeloma Unit, Division of Hematology, University of Torino, TORINO, Italy
⁵Myeloma Unit, Division of Hematology, University of Torino, Torino, Italy
⁶MLL Munchner Leukamie Labor Gmbh, Munchen, Germany
⁷National University Cancer Institute of Singapore, Singapore, Singapore
⁸Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
⁹Erasmus MC Cancer Institute, Rotterdam, Netherlands

David Baker^1*, Milan Bimali, PhD^2,3*, Luis Carrillo, MD⁴, Archana Sachedina^5*, Daisy Alapat, MD⁴, Md shadiqul Hoque, MD^1*, Mathew Kottarathara, MD^6*, Richa Parikh, MD^6*, Amani Erra, MD^6*, Angel Mitma, MD^6*, Pankaj Mathur, MD^6*, Guido Tricot, MD, PhD^1*, Sharmilan Thanendrarajan, MD¹, Maurizio Zangari, MD, FACP¹, Frits van Rhee, MD⁷ and Carolina D. Schinke, MD⁸

¹Myeloma Center, Division of Hematology/Oncology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR
²Arkansas Children’s Nutrition Center, Arkansas Children's Hospital, Little Rock, AR
³Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR
⁴Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR
⁵Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR
⁶Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR
⁷Myeloma Center, Division of Hematology/Oncology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas For Medical Sciences, Little Rock, AR
⁸Myeloma Center, Division of Hematology/Oncology, Winthrop P. Rockefeller Cancer Institute, Myeloma Institute, Little Rock, AR

Mona-Elisabeth R. Revheim, MD, PhD^1,2*, Jakob Nordberg Nørgaard, MD^2,3,4*, Hilde Feiring Philips, MD^1*, Alexander Sherwani, BSc^1*, Syed Nuruddin, DVM, PhD^5*, James P Connelly, MD, PhD^1*, Fredrik Schjesvold, MD, PhD^3,4 and Caroline Stokke, PhD^1,6*

¹Division for Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway
²Institute of Clinical Medicine, University of Oslo, Oslo, Norway
³Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway
⁴KG Jebsen Center for B Cell Malignancies, University of Oslo, Oslo, Norway
⁵Norwegian Medical Cyclotron Centre, Oslo, Norway
⁶Institute of Physics, University of Oslo, Oslo, Norway

Marina Martello^1*, Andrea Poletti^2*, Enrica Borsi^1*, Vincenza Solli^2*, Silvia Armuzzi^2*, Ilaria Vigliotta^1*, Elena Zamagni, MD^2*, Lucia Pantani, MD, PhD^1*, Serena Rocchi^2*, Katia Mancuso^2*, Paola Tacchetti^1*, Ilaria Rizzello^2*, Antonio Curti, MD PhD¹, Michele Cavo^2* and Carolina Terragna^1*

¹Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
²"Seràgnoli" Institute of Hematology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy

Rowan Kuiper, PhD^1,2*, Mark van Duin, PhD^2*, Martin H Van Vliet^3*, Erik H Van Beers, PhD^1*, Berna Berna Beverloo, PhD^4*, Sonja Zweegman, MD, PhD⁵, Tom Cupedo, PhD^2*, Annemiek Broijl, MD, PhD^2* and Pieter Sonneveld, MD, PhD²

¹SkylineDx, Rotterdam, Netherlands
²Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
³SKYLINEDX, Rotterdam
⁴Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, Netherlands
⁵Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

Jean-Baptiste Alberge^1,2*, Bastien Jamet^1,3*, Clement Bailly^1,2,3*, Cyrille Touzeau^1,2,4*, Jonathan Cruard^1,2*, Thomas Carlier^1,2,3*, Caroline Bodet-Milin^1,2,3*, Michel Cherel^1,2,5*, Philippe Moreau^1,2,4*, Stephane Minvielle^1,2,4* and Francoise Kraeber-Bodere^1,2,3,5*

¹Site de Recherche Intégrée sur le Cancer (SIRIC), Imaging and Longitudinal Investigations to Ameliorate Decision-making (ILIAD), INCA-DGOS-Inserm 12558, Nantes, France
²Université de Nantes, CHU Nantes, CNRS, Inserm, CRCINA, Nantes, France
³Nuclear Medicine Unit, University Hospital, Nantes, France
⁴Haematology Department, University Hospital, Nantes, France
⁵Nuclear Medicine Unit, ICO Cancer Center Gauducheau, Saint-Herblain, France

Chenxing Du, MD^1*, Yi Wang^2*, Xue-Han Mao, MD^2*, Yuting Yan^3,4*, Jiahui Liu^3*, Huishou Fan^3*, Yan Xu^2*, Weiwei Sui, MD^2*, Shuhui Deng, MD^3*, Fu Mingwei, MD^2*, Chengwen Li^5*, Jiawei Zhao^5*, Shuhua Yi, MD^5*, Dehui Zou, MD^5*, Yaozhong Zhao^5*, Lugui Qiu, MD³ and Gang An, MD, PhD^2*

¹National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin City, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin City, China
³National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁴Department of Systems Biology, Beckman Research Institute, City of Hope, Monrovia, CA
⁵State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, TIANJIN, China

Chengcheng Liao, PhD, MD^1,2*, Srikanth Talluri, PhD^1,2*, Subodh Kumar, PhD^1,2*, Leutz Buon^2*, Jiangning Zhao, PhD, MD^2*, Lakshmi B. Potluri, MBBS^1,2*, Rao Prabhala^1,2, Masood A. Shammas, PhD^1,2* and Nikhil C. Munshi, MD^1,2,3

¹VA Boston Healthcare System, Boston, MA
²Dana-Farber Cancer Institute, Boston, MA
³Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

Christina Y Yu, BSc^1,2*, Brian A Walker, PhD¹, G David Roodman, MD, PhD¹, Kun Huang, PhD^1,3*, Michel Sadelain, MD, PhD⁴ and Fabiana Perna, MD, PhD^1*

¹Department of Medicine, Indiana University School of Medicine, Indianapolis, IN
²Department of Biomedical Informatics, The Ohio State University, Columbus, OH
³Regenstrief Institute, Indianapolis, IN
⁴Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY

Alissa Visram, MD¹, Iuliana Vaxman, MD, BA^1,2,3*, Abdullah S. Al Saleh, MBBS^1,4, Harsh Parmar, MD¹, Angela Dispenzieri, MD⁵, Prashant Kapoor, MD¹, Martha Q. Lacy, MD¹, Morie Gertz¹, Francis K. Buadi, MB, CHB^5*, Suzanne R. Hayman, MD⁵, Rahma M Warsame, MD⁵, David Dingli, MD, PhD¹, Taxiarchis Kourelis, MD¹, Mustaqeem A. Siddiqui, MD, MBA⁵, Wilson I Gonsalves, MD⁵, Eli Muchtar, MD^1*, John A. Lust, MD, PhD⁵, David L. Murray, MD, PhD^6*, S. Vincent Rajkumar, MD⁵ and Shaji K. Kumar, MD¹

¹Mayo Clinic Rochester, Division of Hematology, Rochester, MN
²Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
³Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel
⁴College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
⁵Division of Hematology, Mayo Clinic, Rochester, MN
⁶Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Ariel Kleman, MD¹, Arun K Singavi, MD, MS², Lauren Pommert, MD, MS³, Michael T Zimmerman, PhD^4*, Wendy Demos^5*, Angela Mathison, PhD^5*, Sridhar Rao, MD, PhD⁶, Karen-Sue Carlson, MD, PhD⁶ and Parameswaran Hari, MBBS, MD^7,8

¹Division of Hematology & Oncology, Medical College of Wisconsin, Milwaukee, WI
²Arizona Center for Cancer Care, Chandler, AZ
³Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁴Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, WI
⁵Medical College of Wisconsin, Milwaukee, WI
⁶Versiti Blood Research Institute, Medical College of Wisconsin, Milwaukee, WI
⁷CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
⁸Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Brookfield, WI

Maryam Salehi, MD, MPH^1*, Daniel O. Stram, PhD^2*, Jose A Aparicio^3*, Liliana Aguinada^4*, Victoria K. Cortessis, PhD^5*, Maximo J. Marin, M.D.^4*, Loic Le Marchand, M.D., Ph.D.^6*, Christopher Haiman, ScD^7*, Lynne Wilkens, DrPH^8*, Jane Emerson, M.D., Ph.D.^9* and Wendy Cozen, D.O., M.P.H.¹⁰

¹Center for Genetic Epidemiology, University of Southern California, Los Angeles, CA
²Department of Preventive Medicine, University of Southern California, Los Angeles, CA
³USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA
⁴Department of Pathology, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA
⁵Norris Comprehensive Cancer Center, Keck School of Medicine At USC, Los Angeles, CA
⁶University of Hawaii Cancer Center, Honolulu, HI
⁷Center for Genetic Epidemiology, Department of Preventive Medicine, University of Southern California, Los Angeles, CA
⁸University of Hawai'i Cancer Center, Honolulu, HI
⁹Department of Pathology, Keck School of Medicine of USC, Los Angeles, CA
¹⁰USC Norris Comprehensive Cancer Center, University of Southern California, Department of Preventive Medicine, Los Angeles, CA

Jule F Vasquez, MD¹, Edgar Diaz, MD^2* and Ebert Poquioma, MD^2*

¹Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru
²Department of Epidemiology, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru