Deirdre Nolfi-Donegan, MD¹, Gowtham K Annarapu, PhD², Cheryl A Hillery, MD¹ and Sruti Shiva, PhD^3,4,5*

¹Pediatric Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA
²University of Pittsburgh, Pittsburgh, PA
³Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
⁴Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA
⁵Center for Metabolism and Mitochondrial Medicine (C3M), University of Pittsburgh, Pittsburgh, PA

Adrienne Lee, MD^1,2, Lorriane Chow, BSc, MD, FRCPC^3*, Leslie Skeith, MD⁴, Joshua A Nicholas, BHSc, MD^5*, Man-Chiu Poon, MD⁶, Alastair W. Poole, MA, PhD, VetMB^7* and Ejaife O Agbani, PhD, BPharm, MSc⁸

¹Department of Medicine, Cumming School of Medicine University of Calgary, Calgary, AB, Canada
²Southern Alberta Rare Blood & Bleeding Disorders Comprehensive Care Clinic, Calgary, AB, Canada
³Department of Anaesthesiology, Perioperative and Pain Medicine, University of Calgary, CALGARY, AB, Canada
⁴University of Calgary, Calgary, AB, Canada
⁵Department of Anesthesiology, Perioperative and Pain Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
⁶Division of Hematology, Department of Medicine, Foothills Hospital, University of Calgary, Calgary, AB, CAN
⁷School of Medical Sciences, University of Bristol, Bristol, GBR
⁸Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, CALGARY, AB, Canada

Rong Wei^1,2*, Xiaojun Huang, MD¹ and Bing Su^2*

¹Peking University Institute of Hematology, Peking University People's Hospital, Beijing, China
²Shanghai Jiao Tong University School of Medicine, Shanghai, China

Jacqueline Adam, PhD^1*, Thomas Gentinetta, PhD^1*, Svetlana Diditchenko, PhD^1*, Alexander Schaub, PhD^1*, Gregory J Kato, MD², Nathan Brinkman, PhD^3* and Adrian Zuercher, PhD^1*

¹Research and Development, CSL Behring AG, Bern, Switzerland
²Clinical Research & Development, CSL Behring, King of Prussia
³Research & Development, CSL Behring, Kankakee, IL

Liang Li, PhD^1*, Junyan Wang^2*, Jieyu Ye, PhD^2*, Liuming Yang^3*, Beng H Chong, MBBS, PhD^4,5 and Mo Yang^1,3*

¹The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China
²Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
³Lianjiang People's Hospital, Lianjiang, China
⁴Medicine, University of New South Wales, Kogarah, Australia
⁵St George Hospital, Sydney, Australia