Michael Fuchs^1*, Annette Plütschow^1*, Carsten Kobe, MD^2*, Richard Greil, MD³, Julia Meissner, MD^4*, Max S. Topp, MD⁵, Helmut Ostermann, MD^6*, Judith Dierlamm, MD^7*, Johannes Mohm, MD^8*, Julia Thiemer, MD^9*, Martin Sökler, MD^10*, Andrea Kerkhoff, MD^11*, Miriam Ahlborn, MD^12*, Teresa V Halbsguth, MD^13*, Sonja Martin, MD^14*, Ulrich Keller^15,16*, Stefan Balabanov, MD, PhD^17*, Thomas Pabst, MD¹⁸, Martin Vogelhuber, MD^19*, Andreas Hüttmann, MD²⁰, Martin Wilhelm, MD²¹, Josée Zijlstra, MD, PhD^22*, Alden Moccia, M.D.^23*, Georg Kuhnert^24*, Paul J Bröckelmann, MD^1*, Bastian von Tresckow, MD^25,26*, Beate Klimm, MD^27*, Andreas Rosenwald, MD^28*, Hans Eich, MD^29*, Christian Baues, MD^30*, Simone Marnitz, MD^30*, Michael Hallek, MD^31*, Volker Diehl, MD³², Markus Dietlein, MD^33*, Andreas Engert, MD³⁴ and Peter Borchmann, MD³⁴

¹University of Cologne, German Hodgkin Study Group (GHSG) and Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Cologne, Germany
²Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
³Illrd Medical Department, Paracelcus Medical University and Salzburg Cancer Research Institute and AGMT (Arbeitsgemeinschaft Medikamentöse Tumortherapie), Salzburg, Austria
⁴Medicine V, University of Heidelberg, Heidelberg, Germany
⁵Medizinische Klinik Und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany
⁶LMU, University Hospital of Munich, Munich, Germany
⁷Department of Oncology and Hematology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⁸Onkopraxis Dresden, Dresden, Germany
⁹Department of Hematology and Oncology, Klinikum der Philipps-Universität Marburg, Marburg, Germany
¹⁰Innere Medizin II, University Hospital Tübingen, Tübingen, Germany
¹¹Department of Medicine A, University Hospital Muenster, Muenster, Germany
¹²Medizinische Klinik III, Städtisches Klinikum Braunschweig, Braunschweig, Germany
¹³Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt/M., Franfkurt, Germany
¹⁴Department of Hematology and Oncology, Robert-Bosch-Hospital, Stuttgart, Germany
¹⁵Department of Medicine III, Technical University of Munich, Munich, Germany
¹⁶Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
¹⁷Department of Medical Oncology and Hematology,, University Hospital Zurich, Zurich, Switzerland
¹⁸Department of Medical Oncology, University Hospital/Inselspital Bern, University of Bern, Switzerland, Bern, Switzerland
¹⁹Klinik und Poliklinik für Innere Medizin III, Universitätsklinik Regensburg, Regensburg, Germany
²⁰Department of Hematology, University Hospital Essen, Essen, Germany
²¹Klinikum Nurnberg, Nurnberg, DEU
²²Amsterdam UMC, Location VUMC, Amsterdam, NLD
²³Division of Medical Oncology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
²⁴Nuklearmedizin Siegen / Kreuztal, Siegen, Germany
²⁵German Hodgkin Study Group (GHSG) and Department I of Internal Medicine, Center of Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), University of Cologne, Cologne, Germany
²⁶Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
²⁷Kliniken Maria Hilf GmbH, Klinik für Hämatologie, Onkologie und Gastroenterologie, Mönchengladbach, Germany
²⁸Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany
²⁹Department of Radiotherapy, University Hospital of Muenster, Muenster, Germany
³⁰Faculty of Medicine and University Hospital Cologne, University Hospital Cologne, Department of Radiooncology and Cyberknife Center, Cologne, Germany
³¹Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Düsseldorf, German CLL Study Group, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany, Cologne, Germany
³²German Hodgkin Study Group (GHSG), University of Cologne, Cologne, Germany
³³Faculty of Medicine and University Hospital Cologne, University Hospital of Cologne, Department of Nuclear Medicine, Cologne, Germany
³⁴German Hodgkin Study Group (GHSG) and Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), University of Cologne, Cologne, Germany

Angie Mae Rodday, PhD¹, Susan K Parsons, MD, MRP^1,2, Carlton Scharman, MD², Ranjana Advani, MD³, Massimo Federico, MD⁴, Jonathan W. Friedberg, MD, MSSc⁵, Andrea Gallamini, MD^6*, David C. Hodgson, MD, MPH, FRCPC^7*, Peter Hoskin, MD^8*, Martin Hutchings, MD, PhD^9*, Peter Johnson, MD, FRCP¹⁰, Kara M. Kelly, MD¹¹, Brian K. Link, MD¹², John A. Radford, MD, FMedSci^13*, Pier Luigi Zinzani, MD¹⁴, James R. Cerhan, MD, PhD¹⁵, John Raemaekers, MD^16*, Andrew M. Evens, DO, MMSc¹⁷ and On Behalf Of The HoLISTIC Consortium^2,17*

¹Institute for Clinical Research & Health Policy Studies, Tufts Medical Center, Boston, MA
²Tufts Medical Center, Tufts University School of Medicine, Boston, MA
³Division of Oncology, Department of Medicine, Saul A. Rosenberg Professor of Lymphoma, Stanford Cancer Institute, Stanford, CA
⁴CHIMOMO department, Università degli Studi di Modena e Reggio Emilia, Modena, Italy
⁵Division of Hematology/Oncology, University of Rochester, Rochester, NY
⁶Research Innovation and Statistics, Antoine-Lacassagne Cancer Centre, Nice, France
⁷Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁸Mount Vernon Hospital, London, GBR
⁹Department of Hematology; Finsen Centre, National Hospital, Copenhagen University Hospital, Copenhagen, Denmark
¹⁰Southampton General Hospital School of Medicine, Southampton, United Kingdom
¹¹Department of Pediatric Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY
¹²Division of Hematology, Oncology, and Blood & Marrow Transplantation, University of Iowa, Iowa City, IA
¹³The University of Manchester and The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom
¹⁴Istituto di Ematologia "Seràgnoli", Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università degli Studi, Bologna, Italy
¹⁵Division of Hematology, Mayo Clinic, Rochester, MN
¹⁶Radboud University Medical Center, Nijmegen, NLD
¹⁷Rutgers Cancer Institute of New Jersey, New Brunswick, NJ

Kristin C. Marr, MD¹, Jonathan Simkin, MPH^2*, Andrea C. Lo, MD^3*, Joseph M. Connors, MD⁴, Alina S. Gerrie, MD, MPH⁵, Diego Villa, MD MPH⁴, Ciara L. Freeman, MSc, MBBChir⁵, David W. Scott, MBChB, PhD⁴, Greg Hapgood, BMBS, FRACP, FRCPA⁶, Laurie H. Sehn, MD, MPH⁷, Ryan Woods, MSc PhD^8* and Kerry J. Savage, MD MSc⁴

¹Division of Pediatric Hematology/Oncology, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada
²Cancer Control Research, BC Cancer Research Centre, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada
³Division of Radiation Oncology, BC Cancer, University of British Columbia, Vancouver, BC, Canada
⁴Centre for Lymphoid Cancer, Department of Medical Oncology, BC Cancer and University of British Columbia, Vancouver, BC, Canada
⁵BC Cancer Centre for Lymphoid Cancer and The University of British Columbia, Vancouver, BC, Canada
⁶Department of Haematology, Princess Alexandra Hospital, Brisbane, QLD, Australia
⁷Centre for Lymphoid Cancer, Department of Medical Oncology, BC Cancer and The University of British Columbia, Vancouver, BC, Canada
⁸Cancer Control Research, BC Cancer Research Centre, Faculty of Health Sciences, Simon Fraser University, Vancouver, BC, Canada

Michael S. Khodadoust, MD, PhD¹, Tatyana A. Feldman, MD², Dok Hyun Yoon^3*, Costas K. Yannakou, MBBS (Hons), FRACP, FRCPA^4*, Dejan Radeski, MBBS, FRACP, FRCPA^5*, Youn H. Kim, MD⁶, Neha Mehta-Shah, MD⁷, Amit Khot, MBBS, MD, MRCP, FRCPath, FRACP⁸, Ryan A. Wilcox, MD⁹, Won Seog Kim, MD, PhD^10*, Steven M. Horwitz, MD¹¹, Joseph J. Buggy, PhD¹², Andrew Hotson, PhD^12*, Craig M. Hill, PhD^12*, Brian Munneke, PhD^12*, Suresh Mahabhashyam, MD^12*, Richard A. Miller, MD¹², James W. Janc, PhD^12* and Mehrdad Mobasher, MD, MPH¹²

¹Division of Medical Oncology, Stanford University School of Medicine, Stanford, CA
²John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ
³Asan Medical Center/University of Ulsan College of Medicine, Seoul, Korea, Republic of (South)
⁴Epworth HealthCare, Melbourne, Australia
⁵Linear Clinical Research and Sir Charles Gairdner Hospital, Nedlands, Australia
⁶Stanford University School of Medicine and Stanford Cancer Institute, Stanford, CA
⁷Division of Medical Oncology, Washington University School of Medicine, St Louis, MO
⁸Department of Clinical Haematology, Peter MacCallum Cancer Centre, Melbourne, Australia
⁹Rogel Cancer Center, University of Michigan, Ann Arbor, MI
¹⁰Hematology and Oncology, Department of Medicine, Samsung Medical Center, Seoul, Korea, Republic of (South)
¹¹Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹²Corvus Pharmaceuticals, Inc., Burlingame, CA

Amira Marouf^1,2*, Anne Ségolène Cottereau, MD^3*, Guillemette Fouquet, MD^4*, Salim Kanoun, MD^5*, Patricia Franchi, MD^6*, Romain Ricci^7*, Michel Meignan, MD^8*, David Sibon, MD, PhD^9*, Thomas Gastinne, MD^10*, Cecile Borel, MD^11*, Mohammad Hammoud, MD^12*, Guillaume Sicard, MD^13*, Romane Gille^14*, Doriane Cavalieri, MD^15*, Aspasia Stamatoulas Bastard, MD^16*, Lauriane Clement-Filliatre, MD^17*, Julien Lazarovici, MD^18*, Adrien Chauchet, MD^19*, Luc Mathieu Fornecker, MD, PhD^20,21*, Sandy Amorin, MD^22*, Mathieu Roquet^4*, Nicole Raus, Data Manager^23*, Rene-Olivier Casasnovas, MD^24,25*, Guillaume Cartron, MD, PhD^26,27*, Hervé Ghesquieres, MD, PhD^28*, Pauline Brice, MD^29*, Olivier Hermine^30,31, Didier Bouscary, MD, PhD^4,32*, Marie Thérèse Rubio, MD, PhD^33,34*, Jerome Tamburini, MD, PhD^35,36,37* and Benedicte Deau Fischer^4,6,38*

¹CHU Cochin, Paris, France
²INSERM UMR 1163 Institut Imagine, Paris Descartes University, Faculty of medicine, Sorbonne Paris Cité, Paris, France., Paris, France
³Nuclear Medicine, APHP Cochin Hospital, PARIS, France
⁴Hematology Department, CHU Cochin, Paris, France
⁵Institut universitaire du cancer Toulouse- Oncopole, Toulouse, France
⁶Cochin Hospital, Hematology Department, Paris, France
⁷LYSARC, The Lymphoma Academic Research Organisation, Créteil, FRA
⁸LYSA, Paris, France
⁹INSERM UMR 1163 & CNRS URL 8254, Hematology Department, Necker University Hospital, APHP, Paris, France, Paris, France
¹⁰Clinical Hematology, Nantes University Hospital, Nantes, France
¹¹Institut Universitaire du Cancer de Toulouse Oncopole, Hematology Department, Toulouse, France
¹²Lymphoid Malignancies, Henri Mondor Hospital, Creteil, France
¹³Hematology Department, Aix Marseille University, Marseille, France
¹⁴Leon Berard Hospital, Lyon, France
¹⁵Centre Hospitalier Universitaire Estaing, Hematology Department, Clermont Ferrand, France
¹⁶Henri Becquerel Center, Rouen, France
¹⁷CHRU Nancy Brabois, Vandoeuvre Les Nancy, France
¹⁸Department of hematology, Gustave Roussy Cancer Campus Grand Paris, Villejuif CEDEX, France
¹⁹Hematology Department, Besancon University Hospital, Besancon, France
²⁰Department of Hematology, Strasbourg University Hospital, Strasbourg, France
²¹UMR-S1113 - IRFAC, INSERM, Faculté de Médecine, STRASBOURG, France
²²Hopital Saint Vincent de Paul, Lille, France
²³SFGM-TC, Lyon, France
²⁴Hématologie Clinique and INSERM 1231, CHU Dijon, Dijon, France
²⁵Inserm UMR 1231, Dijon, France
²⁶Montpellier University, UMR CNRS 5235, Montpellier, France
²⁷CHU Montpellier, Department of Clinical Hematology, Montpellier, France
²⁸Department of Hematology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre Benite, France
²⁹Hopital Saint-Louis, Paris, France
³⁰Hematology Department, AP-HP Hôpital Necker, University Paris Descartes, Paris, France
³¹Imagine Institute, INSERM U1163, University of Paris, Paris, France
³²Paris Descartes University, Sorbonne Paris Cité, Paris, France
³³CNRS UMR 7365, Équipe 6, Biopôle de L'Université de Lorraine, Vandoeuvre Les Nancy, France
³⁴CHRU Nancy, Hôpital Brabois, Vandœuvre-les Nancy, France
³⁵Translational Research Centre in Onco-hematology, Faculty of Medicine, University of Geneva, Geneva, Switzerland
³⁶Institut Cochin, Département Développement, Reproduction, Cancer, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 8104, Institut National de la Santé et de la Recherche Médicale (INSERM) U1016, Paris, France
³⁷Hematology department, CHU Cochin, Paris, France
³⁸Hematolgy Department, CHU Cochin, Paris, France

Aishwarya Ravindran, MBBS¹, Andrew L. Feldman, MD², Rhett P. Ketterling, MD^3*, Surendra Dasari, PhD^4*, Karen Rech, MD^2*, Ellen D. McPhail, MD², Paul J Kurtin, MD² and Min Shi, MD, PhD¹

¹Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
²Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
³Division of Genomics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁴Department of Health Sciences Research, Mayo Clinic, Rochester, MN

Milos D. Miljkovic, MD, MSc¹, Kevin C Conlon, MD^2*, Jennifer Albert, RN^3*, Deborah Allen, RN^2* and Thomas A. Waldmann, MD²

¹Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Washington, DC
²National Cancer Institute, National Institutes of Health, Bethesda, MD
³US Food and Drug Administration, Silver Spring, MD

Justine M. Kahn, MD, MSc¹, Kara M. Kelly, MD², Qinglin Pei, PhD^3*, Yue Wu, MS^4*, Debra L. Friedman, MD⁵, Tara O. Henderson, MD, MPH^6*, David C. Hodgson, MD, MPH, FRCPC^7*, Joel A. Kaplan, DO, MPH^8*, Frank G. Keller, M.D.⁹, Smita Bhatia, MD, MPH¹⁰, Cindy L. Schwartz, MD¹¹ and Sharon M. Castellino, MD, MSc¹²

¹Division of Pediatric Hematology/Oncology, Columbia University Irving Medical Center, New York, NY
²Department of Pediatric Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY
³Children's Oncology Group, Gainesville, FL
⁴Department of Biostatistics, Children's Oncology Group Statistics & Data Center, Gainesville, FL
⁵Vanderbilt University School of Medicine, Nashville, TN
⁶University of Chicago Comer Children’s Hospital, Chicago, IL
⁷Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁸Levine Children's Cancer & Blood Disorders, Carolinas Medical Center, Charlotte, NC
⁹Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
¹⁰Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL
¹¹Children’s Hospital of WI, Medical College of Wisconsin, Milwaukee, WI
¹²Aflac Cancer and Blood Disorders Center, Emory University School of Medicine / Children's Healthcare of Atlanta, Atlanta, GA

Maryam Salehi, MD, MPH^1*, Amie Hwang, PhD, MPH², Julia Simon, Ph.D.^3*, Thomas M. Mack, M.D., M.P.H.^2*, Tim Waterboer, Ph.D.^3* and Wendy Cozen, D.O., M.P.H.⁴

¹Center for Genetic Epidemiology, University of Southern California, Los Angeles, CA
²University of Southern California, Keck School of Medicine of USC, Los Angeles, CA
³German Cancer Research Center, Heidelberg, Germany
⁴USC Norris Comprehensive Cancer Center, University of Southern California, Department of Preventive Medicine, Los Angeles, CA

Qingqing Cai, PhD^1*, Huiqiang Huang, MD, PhD¹, Panpan Liu, MD, PhD^1*, Hui Zhou, MD, PhD^2*, Yajun Li, MD, PhD^2*, Yujing Zhang, MD, PhD^3*, Lixia Lu, MD, PhD^3*, Yan Gao, MD, PhD^1*, Xuanye Zhang, MD, PhD^1*, Yi Xia, MD, PhD^1*, Jun Cai, BMBS^1*, Ning Su, MM^1*, Shuyun Ma, MM^1*, Hang Yang, MD, PhD^1* and Yu Fang, BMBS^1*

¹Department of Medical Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China
²Department of Lymphoma and Hematology, Hunan Cancer Hospital, Changsha, China
³Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China

Monica Mead, MD, BS¹, Henrik Cederleuf, MD^2*, Thomas Relander, MD, PhD^3*, Mats Jerkeman, MD, PhD⁴, Fredrik Ellin, MD, PhD^5* and Daria Gaut, MD⁶

¹Department of Hematology/Oncology, UCLA Medical Center, Santa Monica, CA
²Department of Oncology, Skane University Hospital, Lund, Sweden
³Dept. of Oncology, Skane University Hospital, Lund, Sweden
⁴Department of Oncology, Skane University Hospital, Lund, Skaane Laen, Sweden
⁵Department of Internal Medicine, Kalmar County Hospital, Kalmar, Sweden
⁶Department of Medicine, Univeristy of California Los Angeles, Los Angeles, CA

Philip A Haddad, MD, Dalia Hammoud, MD^* and Kevin M. Gallagher, MD^*

LSUHSC-S/Overton Brooks VAMC, Shreveport, LA

Walter Hanel, MD^1*, Beth A. Christian, MD¹, Kami J. Maddocks, MD², Narendranath Epperla, MD, MS¹, Basem M. William, MD, MRCP¹, Samantha Jaglowski, MD, MPH¹, David A. Bond, MD, BS¹, Yazeed Sawalha, MD¹, John C. Reneau, MD, PhD¹, Jonathan E Brammer, MD¹, Robert Baiocchi, MD, PhD¹, Kristie A. Blum, MD³ and Lapo Alinari, MD, PhD¹

¹Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
²Division of Hematology, Department of Internal Medicine, Ohio State University Hospital, Columbus, OH
³Winship Cancer Institute, Emory University, Atlanta, GA

Priyanka Pullarkat^1*, Rehan Nizamuddin^2*, Shama Jaswal^3*, Marcus Watkins, PhD^4*, Nancy L. Bartlett, MD^5,6*, Amanda F Cashen, MD⁷, Joseph Ippolito, MD, PhD^8* and Neha Mehta-Shah, MD⁹

¹Washington University in St. Louis, St. Louis, MO
²Department of Radiology, Washington University in St. Louis, St. Louis, MO
³Washington University in St. Louis, Saint Louis, MO
⁴Barnes-Jewish Hospital, Washington University in St. Louis, St. Louis, MO
⁵Washington University School of Medicine Siteman Cancer Center, St. Louis, MO
⁶Department of Medicine, Washington University School of Medicine, St. Louis, MO
⁷Washington University School of Medicine, Saint Louis, MO
⁸Department of Radiology, Washington University in St. Louis, Saint Louis, MO
⁹Department of Medicine, Division of Oncology, Washington University, Olivette, MO

Stephanie Sasse, MD^1,2*, Jesko Momotow, MD^3*, Annette Plütschow^4*, Andreas Hüttmann, MD⁵, Nadezda Basara, MD⁶, Christian Koenecke, MD^7*, Sonja Martin, MD^8*, Martin Bentz, MD^9*, Christina Grosse-Thie, MD^10*, Sven Thorspecken, MD^11*, Maike de Wit, MD^12*, Carsten Kobe, MD^13*, Markus Dietlein, MD^14*, Bastian von Tresckow, MD^15*, Michael Fuchs^16*, Peter Borchmann, MD¹⁷ and Andreas Engert, MD¹⁸

¹German Hodgkin Study Group, Cologne, Germany
²Clinic for Hematology and Medical Oncology, University Medicine Göttingen, Göttingen, Germany
³German Hodgkin Study Group (GHSG), Germany and Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), University of Cologne, Germany, Cologne, Germany
⁴German Hodgkin Study Group (GHSG) and Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany
⁵Department of Hematology, University Hospital, Essen, NRW, Germany
⁶Medizinische Klinik I, Malteser Krankenhaus St. Franziskus-Hospital, Flensburg, Germany
⁷Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
⁸Department of Hematology and Oncology, Robert-Bosch-Hospital, Stuttgart, Germany
⁹Stadtisches Klinikum Karlsruhe, Karlsruhe, DEU
¹⁰Department of Medicine, Clinic III – Hematology, Oncology, Palliative Medicine, Rostock University, Rostock, DEU
¹¹Clinic for Hematology, Oncology, Immunology, Hospital Schwabing, Munich, Germany
¹²Department of Medicine - Hematology, Oncology, Palliative Medicine, Vivantes Klinikum Neukölln, Berlin, Germany
¹³Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University Hospital of Cologne, Cologne, Germany
¹⁴Department of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
¹⁵Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
¹⁶First department of Internal Medicine / German Hodgkin Study Group (GHSG), Cologne, Germany
¹⁷German Hodgkin Study Group (GHSG) and Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), University of Cologne, Cologne, Germany
¹⁸Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Cologne, Germany

Paola Ghione, MD^1,2, Joshua Vorstenbosch, MD, PhD, FRCSC^3,4*, Peter G. Cordeiro, MD^5*, Maria E. Arcila, MD^6*, Alison J. Moskowitz, MD¹, Colette Owens, MD¹, Natasha Galasso, BA^1*, Jonas A. Nelson, MD^7*, Ahmet Dogan, MD, PhD⁶, Colleen M. McCarthy, MD, FRCSC^7* and Steven M. Horwitz, MD¹

¹Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Medicine, Lymphoma Service, Roswell Park Comprehensive Cancer Center, Buffalo, NY
³Plastic Surgery Service, Memorial Sloan Kettering Cancer Center, New York
⁴Plastic Surgery Service, Mc Gill University, Montreal, Canada
⁵Plastic Surgery Service, Memorial Sloan Kettering Cancer center, New York, NY
⁶Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Plastic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY

Roch Houot, MD, PhD^1*, Viola Poeschel, MD^2*, Bettina Altmann, PhD^3*, Thomas Illmer, MD^4*, Marc André, MD^5*, Martin Dreyling, MD⁶, Herve Maisonneuve, MD⁷, Herve Tilly, MD, PhD⁸, Stephanie Mayer, MD^9*, Rene-Olivier Casasnovas, MD^10*, Steven Le Gouill, MD, PhD¹¹, Fritz Offner, MD, PhD¹², Guillaume Cartron, MD, PhD^13*, Andrea Kerkhoff, MD^14*, Thomas Weber, MD^15*, Joerg Hoffmann, MD^16*, Marita Ziepert, PhD^3*, Wolfram Klapper, MD^17*, Emmanuel Itti, MD, PhD^18*, Dirk Hellwig^19*, Laurence De Leval, MD²⁰, Andreas Rosenwald, MD^21*, Corinne Haioun, MD, PhD^22*, Laurent Dercle, MD^23*, Philippe Gaulard, MD, PhD^24* and Gerhard Held, MD^2*

¹Hematology Department, CHU Rennes, Rennes, France
²Department of hematology, oncology and rheumatology, Saarland University Medical School, Homburg/Saar, Germany
³Institute for Medical Informatics, Statistics and Epidemiology, University Leipzig, IMISE, Leipzig, Germany
⁴Hematology-Oncology Practice, Dresden, Germany
⁵Department of Hematology, CHU UCL Namur - Site Godinne, Yvoir, Belgium
⁶Department of Medicine III, Klinikum Der Universitaet Muenchen-Campus Grosshadern, Munich, Germany
⁷Clinical Hematology, Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France
⁸Centre Henri Becquerel, Rouen, France
⁹Innere Medizin III, Universitätsklinikum Regensburg, Regensburg, Germany
¹⁰Hématologie Clinique and INSERM 1231, CHU Dijon, Dijon, France
¹¹Service d’hématologie clinique du CHU de Nantes, INSERM CRCINA Nantes-Angers, NeXT Université de Nantes, Nantes, France
¹²University Hospital Ghent, Gent, Belgium
¹³Centre Hospitalier Universitaire de Montpellier, Montpellier, France
¹⁴Department of Medicine A, University Hospital Muenster, Muenster, Germany
¹⁵Department of Medicine IV, Hematology and Oncology, University Hospital Halle, Halle, DEU
¹⁶Hämatologie, Onkologie und Immunologie, Philipps Universität Marburg, Marburg, Germany
¹⁷Department of Hematopathology, University of Schleswig-Holstein, Campus Kiel, Kiel, Germany
¹⁸Service de médecine nucléaire, CHU Henri Mondor, Creteil, FRA
¹⁹Department of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany
²⁰Hôpital Universitaire de Lausanne, Lausanne, Switzerland
²¹Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany
²²Lymphoid Malignancies Unit, Henri Mondor University Hospital, APHP, Créteil, France
²³Columbia University, New York City, NY
²⁴Department of Pathology, Henri Mondor Hospital, APHP, Paris Est-Créteil (UPEC) University Faculty, INSERM UMR-S 955, Créteil, France

Youn H. Kim, MD¹, Michael S. Khodadoust, MD, PhD², Adele de Masson, MD, PhD^3*, Hélène Moins-Teisserenc^4*, Takahiro Ito, MSc^5*, Karen Dwyer, BA^5*, Fiona Herr, PhD^6* and Martine Bagot, MD, PhD^3*

¹Stanford University, Stanford, CA
²Stanford University School of Medicine, Stanford, CA
³Hôpital Saint Louis, APHP, Inserm U976, Université de Paris, Paris, France
⁴INSERM UMR-1160, Institut Universitaire D'Hematologie, Paris, FRA
⁵Kyowa Kirin Pharmaceutical Development, Inc., Princeton, NJ
⁶Kyowa Kirin, Inc., Bedminster, NJ

Limin Gao^1*, Weiping Liu^1*, Wenyan Zhang^1*, Sha Zhao^1*, Yueqiang Song^2*, Jinwei Hu^2*, Kai Wang² and Haiyan Wu^2*

¹West China Hospital of Sichuan University, Chengdu, China
²OrigiMed Co.,Ltd., Shanghai, China

Ankita Tandon^1*, Ning Dong, MD¹, Yumeng Zhang, MD^1*, Emilie Wang, MD^1*, Todd C. Knepper, PharmD², Haipeng Shao, MD^3*, Ling Zhang, MD^3*, Leidy Isenalumhe, MD⁴, Rami Komrokji, MD⁵ and Lubomir Sokol, MD, PhD⁴

¹Department of Internal Medicine, University of South Florida, Tampa, FL
²Department of Individualized Cancer Management, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
³Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁴H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁵Moffitt Cancer Center, Tampa, FL

Luis Alberto de Padua Covas Lage, MD, PhD^1,2*, Claudio Vinicius Brito, MD^3*, Debora Levy, MSc, PhD^4,5*, Hebert Fabricio Culler, MSc, PhD^3,6*, Samuel Campanelli Freitas Couto, PhD^3*, Lucas BO Alves, PhD^7,8*, Maria C Zerbini, MD, PhD, Prof MD^9*, Vanderson Rocha, MD, PhD^{1,8,10,11,12,13,14,15,16,17*} and Juliana Pereira, MD, PhD^{18,19,20,21,22,23}

¹Medical Research Laboratory on Molecular Hematology (LIM-31), Universidade de São Paulo, São Paulo, Brazil
²Departament of Hematology, Hemotherapy and Cell Therapy, Hospital Das Clinicas Da Universidade De Sao Paulo, São Caetano do Sul, SP, Brazil
³Department of Hematology, Hemotherapy and Cell Therapy, Universidade de São Paulo (USP), Sao Paulo, Brazil
⁴Medical Research Laboratory on Immunology and Histocompatibility (LIM-19), Universidade de São Paulo, São Paulo, Brazil
⁵Department of Hematology- Hospital das Clínicas da Faculdade de Medicina da USP- HCFMUSP, Universidade de São Paulo (USP), Sao Paulo, Brazil
⁶Medical Laboratory Investigation 31 - LIM31, Universidade de São Paulo (USP), Sao Paulo, Brazil
⁷Serviço de Hematologia, Hemoterapia e Terapia Celular - Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo/Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil
⁸University of Sao Paulo, Sao Paulo, Brazil
⁹Pathology department, Universidade de São Paulo, Sao Paulo, Brazil
¹⁰Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
¹¹Bone Marrow Transplant Department, Hospital Sírio Libanês, São Paulo, Brazil
¹²Department of Clinical Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
¹³Division of Hematology, Hospital das Clínicas da Faculdade de Medicina (HCFMUSP), University of São Paulo Medical School, University of São Paulo, São Paulo, Brazil
¹⁴Universidade de São Paulo, São Paulo, Brazil
¹⁵Instituto do Cancer de São Paulo (ICESP), University of São Paulo Medical School, University of São Paulo, São Paulo, Brazil
¹⁶Centro de Oncologia, Hospital Sírio Libanês, São Paulo, Brazil
¹⁷Division of Hematology, Transfusion Medicine and Cell Therapy, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
¹⁸Instituto, Sao Paulo, SP, BRA
¹⁹PRQFSA, Sao Paulo, SP, BRA
²⁰Division of Hematology, Hospital das Clínicas da Faculdade de Medicina (HCFMUSP), Sao Paulo, Universidade de Sao Paulo, Sao Paulo, AC, BRA
²¹MEDICINE SCHOOL OF SAO PAULO UNIVERSITY, SAO PAULO, BRA
²²Division of Hematology, Hospital das Clínicas da Faculdade de Medicina (HCFMUSP), Universidade de Sao Paulo, São Paulo, Brazil
²³Instituto do Cancer do Estado de Sao Paulo da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil

Paul J. Hampel, MD¹, Sameer A. Parikh, MD¹, Timothy G. Call, MD¹, Mithun Vinod Shah, MD, PhD¹, Nabila Nora Bennani, MD², Aref Al-Kali, MD¹, Kari G Rabe^3*, Yucai Wang, MD, PhD¹, Eli Muchtar, MD^4*, Jose F. Leis, MD, PhD⁵, Saad S. Kenderian, MD¹, Amber B. Koehler, PA-C, MS^1*, Susan M. Schwager^1*, Daniel L. Van Dyke, PhD⁶, Susan L. Slager, PhD^3*, Neil E. Kay, MD¹, Min Shi, MD, PhD⁶ and Wei Ding, MD, PhD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
³Department of Health Sciences Research, Mayo Clinic, Rochester, MN
⁴Mayo Clinic Rochester, Division of Hematology, Rochester, MN
⁵Division of Hematology and Medical Oncology, Mayo Clinic Health System, Phoenix, AZ
⁶Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN