-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

503. Clonal Hematopoiesis: Aging and Inflammation: Poster II

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
Adult, HSCs, Diseases, Non-Biological, Therapies, Adverse Events, Biological Processes, DNA damage, MPN, Cell Lineage, epigenetics, Study Population, Clinically relevant, genomics, Myeloid Malignancies, hematopoiesis, pharmacology, inflammation
Sunday, December 6, 2020: 7:00 AM-3:30 PM

Masahiro Marshall Nakagawa, MD, PhD1,2, Ryosaku Inagaki, MSc1,3,4*, Yutaka Kuroda, M.D., Ph.D.5*, Yasuhito Nannya, MD, PhD1, Lanying Zhao, M.D., Ph.D1*, Yotaro Ochi, MD1*, June Takeda, MD1*, Qi Xingxing, PhD1*, Akinori Yoda, PhD1*, Ayana Kon, MD, PhD1*, Nobuyuki Kakiuchi, M.D.1*, Hideki Makishima, MD, PhD1, Shuichi Matsuda, M.D., Ph.D.5* and Seishi Ogawa, MD, PhD1,6,7

1Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
2DSK Project, Medical Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan
3DSK Project, Medical Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto City, KYO, Japan
4DSP Cancer Institute, Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan
5Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
6Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan
7Department of Medicine, Center for Haematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden

Karin Gustafsson, PhD1,2,3, Catherine S Rhee, PhD1,4,5*, Elizabeth W Scadden1,3,5*, Vanessa Frodermann6*, Rahul Palchaudhuri, PhD7*, Sharon L. Hyzy, MS7*, Jennifer L Proctor, BS7*, Geoff O Gillard, PhD7*, Anthony E Boitano, PhD7, Michael P. Cooke, PhD7, Matthias Nahrendorf, PhD6* and David T. Scadden, MD1,3,5,8

1Harvard Stem Cell Institute, Harvard University, Cambridge, MA
2Center for Regenerative Medicine, Massachussetts General Hospital, Boston, MA
3Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA
4Department of Stem Cell and Regenerative Biology, Harvard University, Melrose, MA
5Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA
6Center for Systems Biology, Massachusetts General Hospital, Boston, MA
7Magenta Therapeutics, Cambridge, MA
8Massachusetts General Hospital/Harvard Stem Cell Institute, Boston, MA

Abhay Singh, MBBS, MPH1, Matthew Gravina, MD2*, Rutaba Tajammal, MD2*, Annmarie Nowak3*, Renuka Iyer, MD3*, Mark G. Faber, DO4, LunBiao Yan, PhD5*, Duane C. Hassane, PhD6,7, Monica L. Guzman, PhD8,9, Nuria Mencia-Trinchant, PhD10*, Eunice S. Wang, MD11,12 and Swapna Thota, MD3

1Roswell Park Comprehensive Cancer Center, Williamsville, NY
2University at Buffalo, Buffalo, NY
3Roswell Park Comprehensive Cancer Center, Buffalo, NY
4University at Buffalo/Roswell Park Comprehensive Cancer Center, Buffalo, NY
5Weill Cornell Medicine, New York
6Caryl & Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY
7Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY
8Division of Hematology and Oncology, Weill Cornell Medical College Division of Hematology/Oncology, New York, NY
9Department of Pharmacology in Medicine, Weill Medical College of Cornell University, New York, NY
10Division of Hematology and Oncology, Weill Cornell Medicine and The New York-Presbyterian Hospital, New York, NY
11Leukemia Service, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
12Roswell Park Comprehensive Cancer Center, BUFFALO, NY

Hannah Kaizer, MD1, Rakhi P. Naik, MD2, Katie Lobner1* and Alison R. Moliterno, MD3

1Johns Hopkins University School of Medicine, Baltimore, MD
2Department of Medicine, Johns Hopkins Hospital, Baltimore, MD
3Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD

*signifies non-member of ASH