-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

201. Granulocytes, Monocytes, and Macrophages: Poster II Clinically Relevant Abstract

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
Adult, Bleeding Disorders, Hemophilia, Animal models, Bleeding and Clotting, Diseases, Bone Marrow Failure, Genetic Disorders, Pediatric, Biological Processes, immunodeficiency, white blood cells, immune cells, Immune Disorders, Cell Lineage, Infectious Diseases, Neutropenia, Study Population, Clinically relevant, hematopoiesis, immune mechanism, white blood cell disorders, inflammation, microenvironment, multi-systemic interactions
Sunday, December 6, 2020: 7:00 AM-3:30 PM

Masahiro Ikeda1*, Muneyoshi Futami, MD, PhD1*, Bidisha Chanda, MD, PhD2*, Masayuki Kobayashi, MD, PhD1*, Kiyoko Izawa, PhD3* and Arinobu Tojo, MD, PhD1

1Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
2Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, JPN
3Division of Stem Cell Biology, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, JPN

Jean Donadieu, MD, PhD1, Blandine Beaupain, MsC2*, Hélène Lapillonne, MD, PhD3*, Odile Fenneteau, PharmD4*, Flore Sicre de Fontbrune5,6,7,8,9,10*, Yves Bertrand, M.D.11,12*, Nathalie Aladjidi, M.D.13,14*, Vincent Barlogis, M.D., Ph.D.15*, Wadih Abou Chahla, M.D.16*, Thierry Lamy, PhD, MD17,18,19, Aline Moignet Autrel, MD20*, Claire Fieschi, MD, PhD21*, Thierry Leblanc, M.D.22,23*, Despina Moshous, MD, PhD24,25*, Jean Soulier, MD, PhD26,27, Sarah cohen Beaussant28*, Francois Delhommeau, MD, PhD29*, Helene Cavé, PharmD, PhD30*, Catherine Paillard, MD, PhD31*, Elodie Gouache, MD32*, Fares bou Mitri28*, Damien Bonnet33*, Laurence Olivier Faivre34*, Philippe Labrune, MD, PhD35*, Marlène Pasquet, M.D., Ph.D.36*, Virginie Gandemer, MD, PhD37,38*, Nizar Mahlaoui, MD39*, Karl Balabanian40*, Francoise Bachelerie, PhD41* and Christine Bellanne-Chantelot, PhD, PharmD42,43*

1Service d'Hémato-Oncologie Pédiatrique, Hopital Trousseau, Paris, Cedex, France
2Registre des Neutropénies, Hopital Trousseau, AP-HP, Paris, France
3Pediatric Hematology and Oncology Department, Hôpital Armand Trousseau, Paris, France
4Laboratoire d’Hématologie, APHP, Hôpital Robert Debré,, Paris, France
5Hematology and transplantation unit, Saint-Louis Hospital, Paris, France
6Hématologie greffe, Hôpital Saint-Louis, Paris, France
7Centre de Référence Aplasie Médullaire, Service d’Hématologie Greffe, Assistance Publique des Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France
8St-Louis Hospital, APHP, Bone Marrow Transplantation Unit, Paris, France
9Bone-marrow transplantation department, CHU Saint-Louis, Paris, France
10Transplantation Unit, Saint Louis Hospital, APHP, University Paris VII, Paris, France
11Institute of Pediatric Hematology and Oncology, Civil Hospital of Lyon, Claude Bernard University, Lyon, France
12Claude Bernard University, Lyon 1, Lyon, France
13Centre de Référence National des Cytopénies Auto-immunes de l'Enfant (CEREVANCE), Bordeaux, France
14Pediatric Oncology Hematology Unit, Plurithématique CIC (CICP), Centre d’Investigation Clinique (CIC) 1401, INSERM, Bordeaux University Hospital, Bordeaux, France
15Department of Pediatric Hematology, La Timone Hospital, AP-HM, Marseille, France
16Department of Pediatric Hematology, Jeanne de Flandre Hospital, CHRU de Lille, Lille, France
17UMR U1236, Rennes, France
18INSERM CIC 1414, Hospital Pontchaillou, Rennes, France
19Department of Hematology, Rennes University Hospital, Rennes, France
20Clinical Hematology Department, Rennes CHU, Rennes, France
21Service d’Immunologie clinique, Hôpital Saint-Louis, AP-HP, Paris, France
22Pediatric Hematology Unit, Robert-Debré Hospital, AP-HP, Paris, France
23French Reference Center for Aplastic Anemia, Paris, France
24Department of Pediatric Immunology, Hematology and Rheumatology, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
25INSERM UMR 1163, Laboratory of Genome Dynamics in the Immune System, Equipe Labellisée Ligue contre le Cancer, Paris, France
26INSERM U944, Institut Universitaire d'Hématologie, Hopital Saint-Louis, Paris, France
27Hematology Laboratory and INSERM U944, Hopital Saint-Louis Centre Hayem 2ETG, Paris, France
28Centre de référence des neutropénies chroniques Registre des neutropenies, Hopital Trousseau, Paris, France
29APHP, Hôpital Saint Antoine, Service d'hématologie Biologique, Paris, France
30UMRS 1131, Institut de Recherche Saint-Louis, Inserm, University of Paris, Paris, France
31Pediatric Hematology Department, Strasbourg University Hospital, Strasbourg, France
32Pediatric hematology department, Trousseau hospital, APHP, Paris, France
33Centre de Référence Malformations Cardiaques Congénitales Complexes - M3C, Necker Enfants Malades Université de Paris, Paris, FRA
34Centre de Génétique et Centre de Référence Anomalies du Développement et Syndromes Malformatifs, FHU TRANSLAD, Hôpital d'Enfants, Dijon, France, CHU Dijon, DIJON, France
35Service de Pédiatrie Centre de référence des glycogénoses, APHP Hopital Beclere, CLAMART, France
36Pediatric Oncology Immunology Hematology Unit, Children’s hospital, CHU de Toulouse, Toulouse, France
37CHU Hopital Sud, Rennes, FRA
38CNRS UMR 6290 Institut de Génétique et Développement de Rennes, Rennes, France
39CEREDIH, Grp Hosp. Necker-Enfants Malades, Paris, France
40Université de Paris, Saint Louis Research Institute, EMiLy, Inserm U1160, Paris, FRA
41Immunologie 92296 Châtenay-Malabry, Université Paris Saclay Faculte de Pharmacie Inserm U996, Clamart, FRA
42Hopital Pitié Salpétriére APHP, Département de Génétique, AP-HP Hôpital Pitié- Salpêtrière, UPMC Univ Paris 06, Paris, France
43Département de Neurologie, Hôpital Pitié-Salpêtrière, Paris, France

Yanyan Wang1*, Christian Rohde, PhD1*, Fengbiao Zhou, PhD1*, Marco Hennrich, PhD2*, Laura Poisa-Beiro, PhD1*, Volker Eckstein, PhD1*, Caroline Pabst, MD1*, Anne-Claude Gavin, PhD3,4*, Anthony D Ho, MD1 and Carsten Müller-Tidow, MD1*

1Department of Internal Medicine V, University Hospital, Heidelberg University, Heidelberg, Germany
2European Molecular Biology Laboratory, Heidelberg, Germany
3Structural and Computational Biology Unit, EMBL, Heidelberg, Germany
4Molecular Medicine Partnership Unit(MMPU), Heidelberg, Germany

Xiaoli Liu, postgraduate*, Dongyue Zhang, postgraduate*, Hao Wang, Ph.D. candidate*, Qian Ren*, Lina Wang, Ph.D*, Weiping Yuan, PhD, MD and Guoguang Zheng, PhD*

State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Tomasz W. Kaminski, PharmD1, Tomasz Brzoska, PhD1, Egemen Tutuncuoglu, MSc1*, Margaret V. Ragni, MD, MPH2,3 and Prithu Sundd, PhD1,4

1Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
2University of Pittsburgh, Hemophilia Center of Western Pennsylvania, Pittsburgh, PA
3Department of Medicine - Division of Hematology/Oncology, University of Pittsburgh, Pittsburgh, PA
4Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA

Moataz Ellithi, MBBCh1, Hafez M Abdullah, MD1*, Waqas Ullah, MD2*, Radowan Elnair, MD3, Fouad Khalil, MD1* and Faiz Anwer, MD4

1Department of Internal Medicine, University of South Dakota School of Medicine, Sioux Falls, SD
2Department of Internal Medicine, Abington Hospital - Jefferson Health, Abington, PA
3University of Nebraska Medical Center, Omaha, NE
4Taussig Cancer Institute, Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH

Jennifer Croden, MD1*, Jennifer Grossman, MD, FRCPC2 and Haowei Sun, MD, FRCPC1

1Department of Medicine, University of Alberta, Edmonton, AB, Canada
2Department of Hematology and Bone Marrow Transplantation, Department of Medicine, University of Calgary, Calgary, AB, Canada

Antonious Hazim1*, Gordon Ruan, MD1, Aishwarya Ravindran, MBBS2, Jithma P. Abeykoon, MD3, Caleb J Scheckel, DO4, Robert Vassallo, MD3*, Jay Ryu, MD3*, W. Oliver Tobin, MB BCh3*, Matthew Koster, MD3*, Nabila Nora Bennani, MD5, Karen Rech, MD2*, Jason R Young, MD3*, Mithun Vinod Shah, MD, PhD6, Gaurav Goyal, MD6,7 and Ronald S. Go, MD6

1Division of Internal Medicine, Mayo Clinic, Rochester, MN
2Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
3Mayo Clinic, Rochester, MN
4Division of Hematology, Department of Medicine, Mayo Clinic, Scottsdale, AZ
5Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
6Division of Hematology, Mayo Clinic, Rochester, MN
7University of Alabama at Birmingham, Birmingham, AL

*signifies non-member of ASH