Christoph Kornauth^1*, Tea Pemovska, PhD, MSc, BSc^1,2*, Gregory Ian Vladimer, PhD^3*, Günther Bayer^4*, Michael Bergmann^5*, Sandra Eder^6*, Ruth Eichner^2,7*, Harald Esterbauer, MD, PhD^8*, Ruth Exner^5*, Verena Felsleitner-Hauer^9*, Maurizio Forte, MSc^1*, Alexander Gaiger^1*, Hildegard T. Greinix, MD¹⁰, Wolfgang Gstöttner^11*, Marcus Hacker^12*, Alexander Hauswirth, MD^1*, Tim Heinemann^13*, Daniel Heintel^14*, Mir Ali Reza Hoda^15*, Ulrich Jaeger, MD^1,16, Lukas Kazianka, MD^1*, Lukas Kenner, MD^4*, Barbara Kiesewetter, MD^17*, Nikolaus Krall, PhD^3*, Trang Le, BSc^1*, Simone Lubowitzki^1*, Marius E Mayerhoefer^18,19*, Elisabeth Menschel^20*, Olaf Merkel, PhD^4*, Katsuhiro Miura, MD, PhD^21*, Leonhard Muellauer, MD, PhD^4*, Peter Neumeister, MD^10*, Thomas Noesslinger, MD²⁰, Katharina Ocko^22*, Leopold Öhler^23*, Michael Panny, MD^20*, Alexander Pichler, MD^1*, Edit Anna Porpaczy, MD^1*, Gerald Prager, MD^17*, Markus Raderer^17*, Robin Ristl^24*, Reinhard Ruckser, MD²⁵, Julius Salamon^26*, Ana-Iris Schiefer^4*, Ann-Sofie Schmolke, MD^1*, Ilse Schwarzinger, MD^8*, Edgar Selzer^27*, Cathrin Skrabs^1*, Wolfgang R. Sperr, MD^1*, Ismet Srndic, MSc^2*, Renate Thalhammer, MD^8*, Peter Valent, MD^1,28, Emiel Van Der Kouwe^1*, Katrina Vanura, PhD¹, Stefan Vogt^9*, Cora Waldstein^27*, Dominik Wolf, Univ. Prof. Dr.²⁹, Christoph Zielinski^30*, Ingrid Simonitsch-Klupp, MD^4*, Giulio Superti-Furga, PhD^2*, Berend Snijder, PhD^13* and Philipp B. Staber, MD, PhD¹

¹Department of Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
²CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
³Allcyte, Vienna, Austria
⁴Department of Pathology, Medical University of Vienna, Vienna, Austria
⁵Department of Surgery, Medical University of Vienna, Vienna, Austria
⁶Department of Internal Medicine and Hematology/Oncology, Klinikum Klagenfurt, Klagenfurt, Austria
⁷Department of Medicine III, Technical University of Munich, Munich, Germany
⁸Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria
⁹Department of Medicine and Oncology, LKH Wiener Neustadt, Wr. Neustadt, Austria
¹⁰Department of Internal Medicine, Division of Hematology, Medical University of Graz, Graz, Austria
¹¹Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria
¹²Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
¹³Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland
¹⁴Division of Medicine I, Wilhelminenspital, Vienna, Austria
¹⁵Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria
¹⁶Austrian Group Medical Tumor Therapy, Salzburg, Austria
¹⁷Department of Medicine I, Division of Oncology, Medical University Vienna, Vienna, Austria
¹⁸Dept. of Biomedical Imaging and Image-guided Therapy, Medical University Vienna, Vienna, Austria
¹⁹Department of Radiology, Memorial Sloan Kettering Cancer Center, New York
²⁰3rd Medical Department, Hematology & Oncology, Hanusch Hospital, Vienna, Austria
²¹Nihon university school of medicine, Tokyo, Japan
²²Pharmacy Department, Vienna General Hospital, Vienna, Austria
²³Internal Medicine I, Department of Oncology, St. Josef Hospital, Vienna, Austria
²⁴Section for Medical Statistics, Center for Medical Statistics, Informatics and Intelligent Systems, Medical University Vienna, Vienna, Austria
²⁵2. Medical Department, SMZ Ost, Vienna, Austria
²⁶Department of Medicine, Landesklinikum Waidhofen a.d. Ybbs, Waidhofen-Ybbs, Austria
²⁷Department of Radiation Oncology, Medical University Vienna, Vienna, Austria
²⁸Ludwig Boltzmann Institute for Hematology and Oncology, Vienna, Austria
²⁹Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria
³⁰Vienna Cancer Center, Medical University of Vienna, Vienna, Vienna, Austria

Niroshan Nadarajah^1*, Alex Wagner, PhD^2*, Rafael Bejar, MD, PhD³, Mark Ewalt, MD^4*, Annette S. Kim, MD^5*, Michelle M. Le Beau, PhD⁶, Xiaotu Ma, PhD^7*, Manja Meggendorfer, PhD¹, Jamile M. Shammo, MD⁸, Gabriella Ryan⁹, Alexa J. Siddon, MD¹⁰, David P. Steensma, MD¹¹, Matthew J. Walter, MD¹², Ahmet Zehir, PhD^13*, Jinghui Zhang, PhD^14* and Torsten Haferlach, MD¹

¹MLL Munich Leukemia Laboratory, Munich, Germany
²Nationwide Children’s Hospital, Columbus, OH
³University of California - San Diego, La Jolla, CA
⁴University of Colorado Anschutz Medical Campus, Aurora, CO
⁵Boston/Harvard Medical School, Brigham and Women's Hospital, Boston, MA
⁶University of Chicago Comprehensive Cancer Center, Chicago, IL
⁷Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN
⁸Division of Hematology/Oncology, Rush University Medical Center, Chicago, IL
⁹American Society of Hematology, Washington, DC
¹⁰Departments of Laboratory Medicine and Pathology, Yale School of Medicine, Westbrook, CT
¹¹Dana-Farber Cancer Institute, Boston, MA
¹²Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO
¹³Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁴Department of Computational Biology and Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN

Nikhil Patkar, MD^1*, Anam Fatima Shaikh^2,3*, Chinmayee Kakirde^1*, Rakhi Salve^4*, Prasanna Bhanshe^5*, Gaurav Chatterjee, MD^1,2,6*, Sweta Rajpal^7*, Swapnali Joshi^8*, Shruti Chaudhary^1*, Rohan Kodgule^1*, Dhanlaxmi Lalit Shetty, PhD^9,10*, Hasmukh Jain, MD^9,11,12,13*, Bhausaheb Bagal, MD, DM^14,15,16,17*, Hari Menon, MD^11,18, Navin Khattry, MD, DM^15,17,19,20*, Manju Sengar, MD, DM^{9,11,16,21,22}, Prashant Tembhare, MD^1,23*, Papagudi Ganesan Subramanian, MD^1,24* and Sumeet Gujral, MD^1*

¹Hematopathology Laboratory, Tata Memorial Centre, Mumbai, India
²ACTREC, Tata Memorial Centre, Navi Mumbai, India
³Hematopathology Laboratory, Tata Memorial Centre, ACTREC, Navi Mumbai, India
⁴CCE-25, Sector 22, Utsav Chowk - CISF Rd, Owe Camp, Kharghar, Maharashtra, Hematopathology Laboratory, TATA Memorial Centre, ACTREC, Navi Mumbai, India
⁵Tata Memorial Centre, Kharghar, IND
⁶ACTREC, Tata Memorial Centre, Mumbai, Maharashtra, India
⁷Hematopathology Laboratory, TATA Memorial Centre, ACTREC, Navi Mumbai, India
⁸Hematopathology Labortory, Tata Memorial Centre, Mumbai, India
⁹Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
¹⁰Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, ACTREC, Navi Mumbai, Maharashtra, IND
¹¹Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
¹²Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Memorial Center, Mumbai, India
¹³Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Medical Centre, Mumbai, India
¹⁴Department of Medical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India
¹⁵Homi Bhabha National Institute., Mumbai., India
¹⁶Adult hematolymphoid disease management group, Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
¹⁷Bone Marrow Transplant Unit, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre., Navi Mumbai., India
¹⁸Cytecare cancer centre, Medical Oncology, Bengaluru, India
¹⁹BMT unit, Department of Medical oncology, ACTREC., Tata Memorial Centre, Navi Mumbai, India
²⁰Homi Bhabha National University., Mumbai., India
²¹Adult Hematolymphoid Disease Management Group, Department of Medical Oncology,, Tata Memorial Center, Mumbai, India
²²Adult Hematolymphoid Disease Management Group, Tata Memorial Centre, Mumbai, Maharashtra, India
²³Adult & Pediatric Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
²⁴Hematopathology Laboratory, ACTREC, Tata Memorial Centre, Mumbai, Maharashtra, India

Rongqing Pan, PhD^1*, Youzhen Wang^2*, Shumei Qiu^3*, Jeremy Ryan^4* and Ensar Halilovic^5*

¹Dana-Farber Cancer Institute, Houston, TX
²Novartis Institute of Biomedical Research, Oncology Drug Discovery, Cambridge, MA
³Novartis Institutes for Biomedical Research, Cambridge
⁴Dana-Farber Cancer Institute, Boston, MA
⁵Novartis Institutes For Biomedical Research, Oncology Drug Discovery, Cambridge, MA

Ricardo Sanchez^1,2*, Juan Manuel de la Rosa^3*, Yanira Heredia^1,2*, Jaime Carrillo^2*, Laura Rufian^1,2*, Esther Onecha, PhD^3*, Gonzalo Carreño Gomez-Tarragona, MD^3*, Chongwu Wang^4*, María Linares^1*, Jose Sanchez-Pina^1*, Inmaculada Rapado, PhD^3*, Josep-Maria Ribera⁵, Rosa Ayala^1*, Joaquin Martinez-López^1,6* and Santiago Barrio^1,2*

¹Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
²Altum sequencing Co., Madrid, Spain
³Hematology Department, Hospital Universitario 12 de Octubre,, Madrid, Spain
⁴Hosea Precision Medical Technology Co., Ltd., Weihai, Shangdong, China
⁵ICO-Hospital Germans Trias i Pujol, Badalona, Spain
⁶Department of Hematology, Hospital Universitario 12 de Octubre; H12O-CNIO Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, Madrid, Spain