-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

653.O1.6 653. Myeloma/Amyloidosis: Therapy, excluding Transplantation: Novel Therapies Targeting B Cell Maturation Antigen in Relapsed/Refractory Multiple Myeloma

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
multiple myeloma, Biological, antibodies, Adult, Diseases, Therapies, CAR-Ts, Plasma Cell Disorders, immunotherapy, Lymphoid Malignancies, infusion, Study Population, Clinically relevant
Saturday, December 5, 2020: 12:00 PM-1:30 PM
Moderators:
Salomon Manier, MD, PhD, Lille University Hospital and Sandy W. Wong, MD, University of California, San Francisco
Disclosures:
Wong: Bristol Myers Squibb: Research Funding; Fortis: Research Funding; Roche: Research Funding; Janssen: Research Funding; Amgen: Consultancy; Sanofi: Membership on an entity's Board of Directors or advisory committees; GSK: Research Funding.
12:00 PM

Deepu Madduri, MD1*, Jesus G. Berdeja, MD2, Saad Z. Usmani, MD, MBBS, MBA3, Andrzej Jakubowiak, MD, PhD4, Mounzer Agha, MD5, Adam D. Cohen, MD6, A. Keith Stewart, MBChB7*, Parameswaran Hari, MBBS, MD8, Myo Htut, MD9, Elizabeth O’Donnell, MD10*, Nikhil C. Munshi, MD11, David E. Avigan, MD12, Abhinav Deol, MD13, Alexander M. Lesokhin, MD14, Indrajeet Singh, PhD15, Enrique Zudaire, PhD15*, Tzu-Min Yeh16*, Alicia J. Allred, PhD15*, Yunsi Olyslager, MSc17*, Arnob Banerjee, MD15*, Jenna D. Goldberg, MD16*, Jordan M. Schecter, MD16, Carolyn C. Jackson, MD, MPH16*, William Deraedt, MSc17*, Sen Hong Zhuang, MD, PhD16*, Jeffrey R. Infante, MD15*, Dong Geng, PhD18*, Xiaoling Wu, PhD18*, Marlene J. Carrasco, MD, PhD, MPH18*, Muhammad Akram, MD18*, Farah Hossain, PharmD18*, Syed Rizvi, MD18, Frank Fan, MD, PhD19*, Sundar Jagannath, MD20*, Yi Lin, MD, PhD21 and Thomas Martin III, MD22

1Mount Sinai Medical Center, New York, NY
2Sarah Cannon Research Institute and Tennessee Oncology, Nashville, TN
3Levine Cancer Institute, Charlotte, NC
4University of Chicago, Chicago, IL
5UPMC Hillman Cancer Center, Pittsburgh, PA
6University of Pennsylvania, Abramson Cancer Center, Philadelphia, PA
7UHN and the Princess Margaret Cancer Centre, Toronto, ON, Canada
8Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Brookfield, WI
9City of Hope Comprehensive Cancer Center, Duarte, CA
10Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA
11Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
12Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
13Department of Oncology, Blood and Marrow Stem Cell Transplant Program, Karmanos Cancer Institute/Wayne State University, Detroit, MI
14Memorial Sloan Kettering Cancer Center, New York, NY
15Janssen R&D, Spring House, PA
16Janssen R&D, Raritan, NJ
17Janssen R&D, Beerse, Belgium
18Legend Biotech USA Inc., Piscataway, NJ
19Nanjing Legend Biotechnology Co., Ltd., Nanjing, China
20Department of Hematology and Medical Oncology, Mount Sinai Medical Center, New York, NY
21Division of Hematology, Mayo Clinic, Rochester, MN
22University of California, San Francisco, San Francisco, CA

12:15 PM

Hua Jiang, MD1*, Baoxia Dong, MD, PhD2*, Li Gao3*, Li Liu, MD4*, Jian Ge5*, Aili He6*, Juan Du Jr., MD1*, Lu Li1*, Jing Lu, MD1*, Xiequn Chen2*, Yi Zhao7*, Yu Han7*, Yuezhang Chen7*, Yuesheng Xu7*, Hua Zhang7*, Jiaping He7*, Huan Shi7*, Cong Han7*, Xun Ye7*, Zhenguang Wang7*, Jia Liu7*, Lianjun Shen, MD7*, Wei Cao7*, Martina Sersch, MD, PhD8* and Weijun Fu, MD, PhD1*

1Shanghai Changzheng Hospital, Shanghai, China
2Xijing Hospital of Air Force Medical University, Xi’an, China
3The Second Affiliated Hospital of Army Medical University, Chongqing, China
4Tangdu Hospital, Air Force Medical University, Xi'an, China
5The First Affiliated Hospital of Anhui Medical University, Hefei, China
6The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
7Gracell Biotechnologies Ltd., Shanghai, China
8Gracell Biotechnologies Co., Ltd., Shanghai, China

12:30 PM

Shaji K. Kumar, MD1, Magdalini Migkou2*, Manisha Bhutani, MD3, Andrew Spencer4, Sikander Ailawadhi, MD5, Anna Kalff, MBBS4, Farzana Walcott6*, Nabendu Pore6*, Diana Gibson6*, Fujun Wang6*, Lily Cheng6*, Ioannis Kagiampakis6*, Marna Williams6*, Krista Kinneer6*, Yu Jiang6*, Jeffrey Zonder7, Jeremy Larsen8, Shreerang Sirdesai4*, Andrew J. Yee9 and Meletios A Dimopoulos2

1Mayo Clinic Rochester, Division of Hematology, Rochester, MN
2National and Kapodistrian University of Athens, Athens, Greece
3Levine L. Cancer Institute, Charlotte, NC
4The Alfred Hospital, Melbourne, Australia
5Mayo Clinic, Jacksonville, FL
6AstraZeneca, Gaithersburg, MD
7Karmanos Cancer Institute, Detroit, MI
8Mayo Clinic, Phoenix, AZ
9Massachusetts General Hospital Cancer Center, Boston, MA

12:45 PM

Alfred L. Garfall, MD1, Saad Z. Usmani, MD, MBBS, MBA2, María-Victoria Mateos3, Hareth Nahi, MD, PhD4*, Niels W.C.J. Van De Donk5, Jesus F. San-Miguel, MD, PhD6, Albert Oriol Rocafiguera, MD7*, Laura Rosinol, MD, PhD8*, Ajai Chari, MD9, Manisha Bhutani, MD10, Lixia Pei, PhD11*, Raluca Verona, PhD12*, Suzette Girgis, PhD, BPharm, MS11, Tara Stephenson, PhD11*, Jenna D. Goldberg, MD11*, Arnob Banerjee, MD11* and Amrita Krishnan, MD13

1Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Levine Cancer Institute, Charlotte, NC
3Hospital Clinico Universitario de Salamanca, Salamanca, Spain
4Karolinska University Hospital at Huddinge, Stockholm, Sweden
5Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, VU University Medical Center, Amsterdam, Netherlands
6Clinica Universidad de Navarra, Pamplona, Spain
7Institut Català d’Oncologia and Institut Josep Carreras. Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
8Hospital Clínic, Barcelona, Spain
9Mt. Sinai School of Medicine, New York, NY
10Levine Cancer Institute, Atrium Health, Charlotte, NC
11Janssen R&D, Spring House, PA
12Janssen Research & Development, Spring House, PA
13City of Hope, Duarte, CA

1:00 PM

Simon J Harrison, MBBS MRCP (UK) PhD FRCPath (UK) FRACP1,2, Monique C. Minnema, MD, PhD3, Hans C. Lee, MD4, Andrew Spencer, MBBS, FRACP, FRCPA, DM5, Prashant Kapoor, MD6, Deepu Madduri, MD7*, Jeremy Larsen8, Sikander Ailawadhi, MD9, Jonathan L. Kaufman, MD10, Marc S. Raab, MD11*, Parameswaran Hari, MBBS, MD12, Shinsuke Iida, MD, PhD13, Ravi Vij, MBBS14, Faith E. Davies15, Robin Lesley, PhD16*, Vijay V. Upreti, PhD17*, Zhao Yang, PhD18*, Anjali Sharma, MD19*, Alex Minella, MD19 and Suzanne Lentzsch, MD, PhD20

1Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Australia
2Melbourne University, Sir Peter MacCallum Dept of Oncology, Melbourne, Australia
3University Medical Center Utrecht, Utrecht, Netherlands
4The University of Texas M.D. Anderson Cancer Center, Houston, TX
5Alfred Hospital-Monash University, Melbourne, Australia
6Mayo Clinic Rochester, Division of Hematology, Rochester, MN
7Icahn School of Medicine at Mount Sinai, New York, NY
8Mayo Clinic, Phoenix, AZ
9Mayo Clinic, Jacksonville, FL
10Emory University School of Medicine, Atlanta, GA
11Heidelberg University Hospital, Heidelberg, Germany
12Medical College of Wisconsin, Milwaukee, WI
13Nagoya City University Hospital, Nagoya, Japan
14Washington University School of Medicine, St Louis, MO
15NYU Langone, New York, NY
16Clinical Biomarkers and Diagnostics, Amgen Inc, South San Francisco, CA
17Clinical Pharmacology Modeling & Simulation, Amgen Inc., South San Francisco, CA
18Global Biostatistical Science, Amgen Inc., Thousand Oaks, CA
19Early Development, Oncology, Amgen Inc., Thousand Oaks, CA
20Columbia University Medical Center, New York, NY

1:15 PM

Gang An, MD, PhD1*, Weiwei Sui, MD2*, Tingyu Wang3*, Xiaoyan Qu, MD, PhD4*, Xian Zhang, MD5, Junfang Yang5*, Yan Zhang, MD6*, Lu Zhang, MD6*, Judy Zhu, MD7*, Chengxiao Zheng, MD7*, Xiuxiu Yan7*, Xiaoteng Lv, MS7*, Liping Lan, MS7*, Dingzhu Yang7*, Ningning Huo7*, Ting Han, MS7*, Dijun Zhao, MS7*, Shichao Qin7*, Junfeng Wu, PhD7*, Xin Yao, PhD8*, Shigui Zhu, PhD8*, Jiaqiang Ren, MD, PhD8*, Li Zhang, MD8*, Jiaqi Huang, PhD8*, Michael Humphries, MD7*, Yihong Yao, PhD8, Daobin Zhou, MD, PhD9*, Jianyong Li, MD, PhD10 and Peihua Lu, MD5

1Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China
2State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin City, China
3National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
4Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
5Hebei Yanda Lu Daopei Hospital, Langfang, China
6Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
7Cellular Biomedicine Group Inc, Shanghai, China
8Cellular Biomedicine Group Inc, Gaithersburg, MD
9Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
10Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China

*signifies non-member of ASH