-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

642.O2.6 642. CLL: Therapy, excluding Transplantation I

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Adult, antibodies, Biological, Leukemia, CLL, Diseases, Lymphoma (any), Combinations, Hodgkin Lymphoma, Therapies, Non-Hodgkin Lymphoma, B-Cell Lymphoma, DLBCL, Technology and Procedures, cytogenetics, Lymphoid Malignancies, Study Population, Clinically relevant, TKI, molecular testing
Saturday, December 5, 2020: 9:30 AM-11:00 AM
Moderators:
Matthew S. Davids, MD, Dana-Farber Cancer Institute and Chaitra S. Ujjani, MD, University of Washington/Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance
Disclosures:
Davids: AbbVie: Consultancy; Adaptive Biotechnologies: Consultancy; Ascentage Pharma: Consultancy, Research Funding; AstraZeneca: Consultancy, Research Funding; Celgene: Consultancy; Eli Lilly: Consultancy; Genentech: Consultancy, Research Funding; Janssen: Consultancy; Bristol Myers Squibb: Research Funding; Merck: Consultancy; Research to Practice: Honoraria; Syros Pharmaceuticals: Consultancy; Zentalis: Consultancy; Sunesis: Consultancy; Gilead Sciences: Consultancy; Novartis: Consultancy, Research Funding; MEI Pharma: Consultancy, Research Funding; Surface Oncology: Research Funding; Pharmacyclics: Consultancy, Research Funding; TG Therapeutics: Consultancy, Research Funding; Verastem: Consultancy, Research Funding; BeiGene: Consultancy. Ujjani: AstraZeneca: Consultancy, Honoraria, Research Funding; Abbvie: Consultancy, Honoraria, Research Funding; Verastem Oncology: Consultancy, Honoraria; Gilead/Kite: Consultancy, Research Funding; Atara: Consultancy, Honoraria; Genentech: Consultancy, Honoraria; MorphoSys: Consultancy; Epizyme: Consultancy.
9:30 AM

William G. Wierda, MD, PhD1*, Constantine S. Tam, MD2, John N. Allan, MD3, Tanya Siddiqi, MD4*, Thomas J. Kipps, MD, PhD5, Stephen Opat, FRACP, FRCPA, MBBS6*, Alessandra Tedeschi, MD7*, Xavier C. Badoux, MBBS, FRACP, FRCPA8, Bryone J. Kuss, MBBS, PhD, FRACP, FRCPA9*, Sharon Jackson, MD10*, Carol Moreno, MD, PhD11*, Ryan Jacobs, MD12*, John M. Pagel, MD, PhD13, Ian W. Flinn, MD, PhD14, Cathy Zhou, MS15*, Edith Szafer-Glusman, PhD15*, Joi Ninomoto, PharmD15*, James P. Dean, MD, PhD15, Danelle F. James, MD, MAS15 and Paolo Ghia, MD, PhD16

1Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
2Peter MacCallum Cancer Centre & St. Vincent’s Hospital and the University of Melbourne, Melbourne, VIC, Australia
3Weill Cornell Medicine, New York, NY
4City of Hope National Medical Center, Duarte, CA
5University of California, San Diego, Moores Cancer Center, La Jolla, CA
6Monash University, Clayton, VIC, Australia
7ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
8Ministry of Health, Kogarah, NSW, Australia
9Flinders University and Medical Centre, Bedford Park, SA, Australia
10Middlemore Hospital, Auckland, New Zealand
11Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
12Levine Cancer Institute, Charlotte, NC
13Fred Hutchinson Cancer Research Center, Seattle, WA
14Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN
15Pharmacyclics LLC, an AbbVie Company, Sunnyvale, CA
16Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milan, Italy

9:45 AM

Talha Munir, MBBS1*, Rebecca H. Boucher, BSc, MSc, PhD2*, Nichola Webster3*, Surita Dalal, PhD4*, Kristian Brock, PhD2*, Francesca Yates, PhD2*, Chhaya Sankhalpara5*, Donald Macdonald, MBChB, MD, FRCP, PhD, FCRPath6*, Christopher Fegan7*, Alison McCaig, MBChB, FRCPath, PhD, MRCP8*, Anna Schuh, MD9, Andrew Pettitt, MA, MB BChir, PhD, MRCP, MRCPath10*, John G. Gribben, MD, DSc, FRCP, FMedSci, FRCPath11, Piers Patten, MD, PhD12, Stephen Devereux, PhD, FRCP, FRCPath, MRCPath, MB BS12*, Adrian Bloor, PhD, FRCP, FRCPath13*, Christopher P Fox, PhD, FRCPath, MRCP, MBChB14*, Francesco Forconi, MD, PhD, FRCPath15*, Andrew Rawstron, PhD4* and Peter Hillmen, MBChB, PhD16*

1St James University Hospital, Leeds, United Kingdom
2Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom
3St James's University Hospital, Leeds, United Kingdom
4HMDS, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
5Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, ENG, United Kingdom
6Imperial College Healthcare NHS Trust, London, United Kingdom
7University Hospital of Wales, Cardiff, United Kingdom
8The Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom
9Oxford University Hospital NHT Trust, Oxford, United Kingdom
10Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, United Kingdom
11Barts Cancer Institute, London, United Kingdom
12King’s College London and King’s College Hospital NHS Foundation Trust, London, United Kingdom
13The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom
14Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom
15University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
16St. James's University Hospital, Institute of Oncology, Leeds, United Kingdom

10:00 AM

Arnon P. Kater, MD, PhD1, Thomas J. Kipps, MD, PhD2, Barbara Eichhorst, MD3, Peter Hillmen, MBChB, PhD, FRCP, FRCPath4, James D'Rozario5*, Carolyn Owen, MD FRCPC6, Sarit E Assouline, MD, MSc7, Nicole Lamanna, MD8, Tadeusz J. Robak9*, Javier de la Serna10*, Ulrich Jaeger11, Guillaume Cartron, MD, PhD12*, Marco Montillo13, Clemens Mellink14*, Brenda J. Chyla15, Cameron Wilson16*, Jenny Wu17*, Yanwen Jiang17*, Marcus Lefebure16*, Michelle Boyer16* and John F. Seymour, MBBS18

1Cancer Center Amsterdam, Amsterdam, Netherlands
2UCSD Moores Cancer Center, San Diego, CA
3Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Duesseldorf, University of Cologne, Cologne, Germany
4St. James’s University Hospital, Leeds, United Kingdom
5The John Curtin School of Medical Research, Australian National University, Canberra, Australia
6University of Calgary, Calgary, Canada
7Segal Cancer Center, Lady Davis Institute, Jewish General Hospital, Montreal, Canada
8New York-Presbyterian/ Columbia University Medical Center, Herbert Irving Comprehensive Cancer Center, New York, NY
9Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
10Hospital Universitario 12 de Octubre, Madrid, Spain
11Dept. of Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
12Centre Hospitalier Universitaire de Montpellier, Montpellier, France
13Department of Haematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy
14Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
15AbbVie Inc., North Chicago, IL
16Roche Products Ltd, Welwyn Garden City, United Kingdom
17Genentech, Inc., South San Francisco, CA
18Royal Melbourne Hospital, Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia

10:15 AM

Anthony R. Mato, MD1, Stephen J. Schuster, MD2, Francine M. Foss, MD3, Iris Isufi, MD3, Shalin K. Kothari, MD3, Wei Ding, MD, PhD4, Danielle M. Brander, MD5, Andrea Sitlinger, MD5, Allison C. Rosenthal, D.O.6, Jose F. Leis, MD, PhD7, Han W. Tun, MD8, Kaitlin Kennard, RN, BSN2*, Allison R. Nelson, RN2*, Victoria Falco, BSN1*, Celina J. Komari, BS1*, Amber B. Koehler, PA-C, MS4*, Rachel Stowe, RN5*, Wei He, PhD9,10*, Albert Kearney, Ph.D.9*, Min Gui, Ph.D.9*, Tim McKinlay9*, Lindsey E Roeker, MD1, Meghan C. Thompson, MD1 and Scott F. Huntington, MD, MPH3

1Memorial Sloan Kettering Cancer Center, New York, NY
2Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
3Yale Cancer Center, New Haven, CT
4Mayo Clinic, Rochester, MN
5Duke University Medical Center, Durham, NC
6Mayo Clinic, Phoenix, AZ
7Division of Hematology and Medical Oncology, Mayo Clinic Health System, Phoenix, AZ
8Division of Hematology-Oncology and Blood and Marrow Transplantation Program, Mayo Clinic, Jacksonville, FL
9Zhejiang DTRM Biopharma LLC, Plymouth Meeting, PA
10Zhejiang DTRM Biopharma Co. Ltd., Hangzhou Fuyang, China

10:30 AM

Othman Al-Sawaf, MD1*, Can Zhang, PhD2*, Sandra Robrecht, PhD3*, Cameron Wilson4*, Maneesh Tandon, MD5*, Travers Ching6*, Anna-Maria Fink, MD7*, Matthias Ritgen, MD8*, Eugen Tausch, MD9*, Karl-Anton Kreuzer, MD2*, William Schary, PhD10, Clemens-Martin Wendtner11*, Barbara Eichhorst, MD3, Stephan Stilgenbauer, MD12, Yanwen Jiang13*, Michael Hallek14 and Kirsten Fischer, MD3*

1University of Cologne, Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Duesseldorf, Cologne, Cologne, Germany
2Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Düsseldorf, German CLL Study Group, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany, Cologne, Germany
3Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Duesseldorf, University of Cologne, Cologne, Germany
4Roche Products Ltd, Welwyn Garden City, United Kingdom
5Roche Products Limited, Welwyn Garden City, United Kingdom
6Adaptive Biotechnologies, Seattle, WA
7University Hospital Cologne, Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Duesseldorf; Cologne, Cologne, Germany
8Department of Internal Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany
9Department of Internal Medicine III, Ulm University, Ulm, Germany
10AbbVie, North Chicago, IL
11Klinikum Schwabing, Department I of Medicine, Academic Teaching Hospital of University of Munich, Munich, Germany
12Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany
13Genentech, Inc., South San Francisco, CA
14Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf and German CLL Study Group, University of Cologne, Cologne, Germany

10:45 AM

Shuhua Yi, MD1*, Jun Du2*, Ying Yu3*, Yang Jiao4*, Yi Wang5*, Huijun Wang6*, Tingyu Wang7*, Rui Lv3*, Wei Liu8*, Wenjie Xiong, PhD9*, Huimin Liu1*, Wenyang Huang3*, Dehui Zou, MD10*, Gang An11*, Yaozhong Zhao12*, Jianxiang Wang, MD6 and Lugui Qiu, MD3

1lymphoma and myeloma center, National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
2Institute of Hematology and Blood Diseases Hospital, State Key Lab of Experimental Hematology, Chinese Academy of Medical, Science and Peking Union Medical College, Tianjin, China
3National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
4the Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China, tianjin, China
5State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, tianjin, China
6State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
7Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
8State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood, TIANJIN, China
9State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, CHN
10State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, TIANJIN, China
11Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
12Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences,Tianji, Tianjing, CHN

*signifies non-member of ASH