Abdulraheem Yacoub, MD¹, Kristen M. Pettit, MD², Terrence J Bradley, MD³, Aaron T. Gerds, MD, MS⁴, Maciej Tartaczuch, MD^5*, Jake Shortt, FRACP, FRCPA, PhD⁶, Natasha Joan Curtin, MD, FRACP, FRCPA^7*, James M. Rossetti, DO⁸, Kate Burbury, MBBS, FRACP, FRCPA, DPhil^9*, Adam J. Mead, MD, PhD¹⁰, Joachim R Göthert, MD¹¹, Steffen Koschmieder, MD¹², Amber Jones, MA^13*, Jennifer Peppe, BS^14*, Georges Natsoulis, Ph.D.^13*, William S. Stevenson, MBBS, PhD¹⁵, Joanne Ewing, MD, PhD^16*, Claire Harrison, DM, FRCPath¹⁷, Alessandro Vannucchi, MD¹⁸, Justin M Watts, MD¹⁹, David M Ross, MBBS, PhD, FRACP, FRCPA^20*, Moshe Talpaz, MD²¹ and Hugh Young Rienhoff Jr., MD²²

¹The University of Kansas Cancer Center, Leawood, KS
²Rogel Cancer Center, University of Michigan, Ann Arbor, MI
³University of Miami Sylvester Comprehensive Cancer Center, Miami, FL
⁴Taussig Cancer Institute, Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁵School of Clinical Sciences, Monash University, Melbourne, Australia
⁶Department of Haematology, Monash Heatlh, Clayton, Australia
⁷Monash Health, Monash University, Melbourne, Australia
⁸UPMC Hillman Cancer Center, Pittsburgh, PA
⁹Peter MacCallum Cancer Centre, Melbourne, Australia
¹⁰MRC Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
¹¹Department of Hematology, West German Cancer Center (WTZ), University Hospital Essen, Essen, Germany
¹²Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany
¹³Imago Biosciences, Inc., San Carlos, CA
¹⁴Imago BioSciences, Inc., San Carlos, CA
¹⁵Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, Australia
¹⁶University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
¹⁷Department of Clinical Haematology, Guys and St Thomas NHS Trust, London, United Kingdom
¹⁸CRIMM; Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy
¹⁹University of Miami, Coral Gables, FL
²⁰Department of Haematology, Flinders Medical Centre and University, Adelaide, SA, Australia
²¹University of Michigan Medical Center, Ann Arbor, MI
²²Imago Biosciences, San Francisco

Naveen Pemmaraju, MD¹, Jacqueline S. Garcia, MD², Jalaja Potluri, MD³, Leanne Holes, BS, MBA,^3*, Jason Harb, PhD^3*, Paul Jung, PhD^3*, Jessica E. Hutti, PhD^3*, Josef T. Prchal, MD⁴, Srdan Verstovsek, MD, PhD¹ and Claire Harrison, DM, FRCPath⁵

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³AbbVie Inc., North Chicago, IL
⁴Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
⁵Department of Clinical Haematology, Guys and St Thomas NHS Trust, London, United Kingdom

John Mascarenhas, MD¹, Rami Komrokji, MD², Michele Cavo^3*, Bruno Martino, MD^4*, Dietger Niederwieser, MD, PhD⁵, Andreas Reiter, MD^6*, Bart L. Scott, MD⁷, Maria R. Baer, M.D.⁸, Ronald Hoffman, MD¹, Olatoyosi Odenike, MD⁹, Jacqueline Bussolari, PhD¹⁰, Eugene Zhu, PhD^10*, Esther Rose, MD^10*, Laurie Sherman, BSN¹¹, Souria Dougherty, BS, MBA^11*, Faye Feller, MD¹¹, Libo Sun, PhD^11*, Ying Wan, PhD^11*, Aleksandra Rizo, MD, PhD¹¹, Fei Huang, PhD^11* and Jean-Jacques Kiladjian, MD, PhD¹²

¹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
³Seragnoli Institute of Hematology, University of Bologna, Bologna, Italy
⁴Grande Ospedale Metropolitano-G.O.M. Bianchi-Melacrino-Morelli, Reggio Calabria, Italy
⁵University Hospital Leipzig, Leipzig, Germany
⁶University Hospital Mannheim, Mannheim, Germany
⁷Fred Hutchinson Cancer Research Center, Seattle, WA
⁸Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD
⁹University of Chicago, Chicago, IL
¹⁰Janssen Research & Development, LLC, Raritan, NJ
¹¹Geron Corporation, Parsippany, NJ
¹²Hopital Saint-Louis, Paris, France

Srdan Verstovsek, MD, PhD¹, Miklos Egyed, MD, PhD^2*, Ewa Lech-Marańda, MD, PhD^3*, Tomasz Sacha, MD PhD^4*, Viviane Dubruille, MD^5*, Stephen T. Oh, MD⁶, Doroteya Todorieva-Todorova, MD^7*, Francesco Passamonti, MD^8*, Blanca Xicoy, MD^9*, Björn Andréasson, MD, PhD^10*, Daniel El Fassi, MD^11*, Claire Harrison, DM, FRCPath¹², Donal P. McLornan, MRCP, PhD, FRCPath^13*, Mary Frances Frances McMullin, MD, FRCPath, FRCP¹⁴, Christof Scheid, MD¹⁵, MArianne Tang Severinsen, MD, PhD^16*, Mark M Kowalski, MD, PhD^17*, Gregg Smith, PhD^18* and Ruben Mesa, MD¹⁹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Hematológiai Osztály, Somogy Megyei Kaposi Mor Oktato Korhaz, Kaposvar, Hungary
³Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
⁴Department of Hematology, Jagiellonian University Medical College, Krakow, Poland
⁵Clinical Hematology, Nantes University Hospital, Nantes, France
⁶Washington University School of Medicine, Saint Louis, MO
⁷Hematology Division, Medical University, Pleven, BGR
⁸Hematology, Department of Medicine and Surgery, University of Insubria, Ospedale di Circolo, ASST Sette Laghi, Varese, Italy
⁹Hematology Department, Institut Català d'Oncologia-Hospital Germans Trias i Pujol; Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain
¹⁰Hematology section, Uddevalla Sjukhus, NU Hospital Group, Uddevalla, Sweden
¹¹Herlev University Hospital, Copenhagen, KøBenhavn S, DNK
¹²Department of Clinical Haematology, Guys and St Thomas NHS Trust, London, United Kingdom
¹³Systems Cancer Immunology, Comprehensive Cancer Centre, Kings's College Hospital, London, United Kingdom
¹⁴Queens University, Belfast, United Kingdom
¹⁵Department I of Internal Medicine and Center of Integrated Oncology Cologne Bonn, University of Cologne, Cologne, Germany
¹⁶Department of Hematology, Aalborg University Hospital, Aalborg, Denmark
¹⁷Sierra Oncology, Vancouver, BC, Canada
¹⁸Sierra Oncology Inc., Vancouver, BC, Canada
¹⁹UT Health San Antonio Cancer Center, San Antonio, TX

John Mascarenhas, MD¹, Claire Harrison, DM, FRCPath², Andrea Patriarca, MD^3*, Timothy Devos, MD⁴, Francesca Palandri, MD, PhD^5*, Raajit K. Rampal, MD, PhD⁶, Adam J. Mead, MD, PhD⁷, Marina Kremyanskaya¹, Tim C.P Somervaille, PhD, FRCP, FRCPath⁸, Marielle Wondergem, MD^9*, Ronald Hoffman, MD¹⁰, Katarina Luptakova, MD^11*, Jing Wang, PhD^11*, Jessica Christo, MA^11*, Jennifer A Mertz, PhD^11*, Gozde Colak, PhD^12*, James Shao, MS^11*, Suresh Bobba, MD^11*, Patrick Trojer, PhD^11*, Adrian Senderowicz, MD^11*, Srdan Verstovsek, MD, PhD¹³ and Vikas Gupta, MD, FRCP, FRCPath¹⁴

¹Division of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY
²Guy's and St Thomas' Hospital, London, United Kingdom
³Azienda Ospedaliero Universitaria Maggiore della Carità di Novara SCDU Ematologia, Novara, Italy
⁴Department of Hematology and Department of Microbiology and Immunology, University Hospitals Leuven and Laboratory of Molecular Immunology (Rega Institute), KU Leuven, Leuven, Belgium
⁵Institute of Hematology “L. and A. Seràgnoli”, S. Orsola-Malpighi Bologna University Hospital, Bologna, Italy
⁶Leukemia Service, Department of Medicine, Clinical Director, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
⁸The Christie Hospital, Cancer Research UK Manchester Institute, Manchester, United Kingdom
⁹Department of Hematology, Academisch Ziekenhuis Vrije Universiteit, Amsterdam, Netherlands
¹⁰Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
¹¹Constellation Pharmaceuticals, Cambridge, MA
¹²Constellation Pharmaceuticals, CAMBRIDGE, MA
¹³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁴Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada

Srdan Verstovsek, MD, PhD¹, John Mascarenhas, MD², Marina Kremyanskaya², Ronald Hoffman, MD³, Raajit K. Rampal, MD, PhD⁴, Vikas Gupta, MD, FRCP, FRCPath⁵, Moshe Talpaz, MD⁶, Nikki Granacher, MD^7*, Brian Leber, MD⁸, Jean-Jacques Kiladjian, MD, PhD⁹, Alessandro Vannucchi, MD¹⁰, Prithviraj Bose, MD¹¹, Mary Frances McMullin, MD FRCP, FRCPath¹², Shireen Sirhan, MD¹³, Vincent Ribrag, MD¹⁴, Katarina Luptakova, MD^15*, Jessica Christo, MA^15*, Jing Wang, PhD^15*, Jennifer A Mertz, PhD^15*, Gozde Colak, PhD^16*, James Shao, MS^15*, Suresh Bobba, MD^15*, Patrick Trojer, PhD^15*, Adrian Senderowicz, MD^15* and Claire Harrison, DM, FRCPath¹⁷

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Division of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY
³Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁴Leukemia Service, Department of Medicine, Clinical Director, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada
⁶Rogel Cancer Center, The University of Michigan, Ann Arbor, MI
⁷Ziekenhuis Netwerk Antwerpen, Antwerp, Belgium
⁸Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, Hamilton, ON, Canada
⁹Clinical Investigations Center, Saint-Louis hospital, Université de Paris, Paris, France
¹⁰Azienda Ospedaliero Universitaria Careggi, Firenze, Italy
¹¹Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX
¹²Queen's University Belfast, Belfast, United Kingdom
¹³Division of Hematology, Jewish General Hospital, Montreal, QC, Canada
¹⁴Institut Gustave Roussy, Villejuif, France
¹⁵Constellation Pharmaceuticals, Cambridge, MA
¹⁶Constellation Pharmaceuticals, CAMBRIDGE, MA
¹⁷Guy's and St Thomas' Hospital, London, United Kingdom