Ella R Thompson, PhD, BSc^1,2*, Tamia Nguyen^1*, Yamuna Kankanige, PhD^1,2*, Mary Ann Anderson, MBBS, PhD, FRACP, FRCPA^3,4,5, Sasanka M. Handunnetti, MBBS, FRACP, FRCPA^3*, Rachel Thijssen, PhD^4*, Paul Sung-Hao Yeh, MBBS, FRCPA, FRACP^1,2,3*, Constantine S. Tam, MBBS, MD^3,5,6*, John F. Seymour, MBBS^3,5, Andrew W Roberts, MBBS^3,4,5, David Alan Westerman, MBBS, FRCPA, FRACP^1,2,3 and Piers Blombery, MBBS^1,2,3*

¹Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Australia
²Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia
³Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Australia
⁴Blood Cells and Blood Cancer, The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia
⁵Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Australia
⁶Department of Haematology, St Vincent's Hospital, Fitzroy, Australia

Simone Ferrero, MD^1,2, Daniele Grimaldi, MD^2*, Elena Arrigoni^3*, Gian Maria Zaccaria, PhD^2*, Beatrice Alessandria^2*, Elisa Genuardi^2*, Gabriele De Luca^2*, Marco Ghislieri^4*, Alice Di Rocco^5*, Alessandro Re, MD^6*, Vittorio Stefoni, MD, PhD^7*, Federica Cavallo^1,2*, Carola Boccomini, MD^8*, Monica Balzarotti^9*, Vittorio Ruggero Zilioli, MD^10*, Gomes da Silva Maria, MD, PhD^11*, Luca Arcaini^12*, Anna Lia Molinari, MD^13*, Filippo Ballerini, MD^14*, Andres JM Ferreri, MD¹⁵, Benedetta Puccini^16*, Giuseppe A. Palumbo, MD, PhD^17*, Sara Galimberti, MD, PhD^18*, Sergio Cortelazzo, MD^19*, Antonello Di Paolo^3* and Marco Ladetto, MD²⁰

¹Hematology, University of Torino and Hospital "Città della Salute e della Scienza di Torino", Torino, Italy
²Department of Molecular Biotechnologies and Health Sciences, Hematology Division, University of Torino, Torino, Italy
³Pharmacology Unit, University of Pisa, Pisa, Italy
⁴Department of Electronics and Telecommunications, Politecnico di Torino, Turin, Italy
⁵Department of Translational and Precision Medicine, Policlinico Umberto I, Roma, Italy
⁶ASST Spedali Civili, Brescia, ID, Italy
⁷Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy
⁸Hematology Division 2, AOU "Città della Salute e della Scienza di Torino", Turin, Italy
⁹Department of Haematology, Istituto Clinico Humanitas, Rozzano, Italy
¹⁰Ospedale Metropolitano Niguarda, Milano, IT-MI, Italy
¹¹Instituto Português de Oncologia - Centro de Lisboa, Departamento de Hematologia, Lisboa, Portugal
¹²Department of Onco-Hematology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
¹³Hematology Unit, Infermi Hospital, Rimini (FC), Italy
¹⁴Clinic of Hematology, Department of Internal Medicine (DiMI), IRCCS Ospedale Policlinico San Martino, Genova, Italy
¹⁵Onco-Hematology Department, Fondazione Centro San Raffaele, Milan, Italy
¹⁶Hematology Department, University of Florence and AOU Careggi, Firenze, Italy
¹⁷Department of Medical, Surgical and Advanced Technology "G.F. Ingrassia", University of Catania, Catania, Italy
¹⁸Department of Clinical and Experimental Medicine, Section of Hematology, University of Pisa, Pisa, Italy
¹⁹Clinica Humanitas/Gavazzeni, Bergamo, Italy
²⁰Division of Hematology, A.O. SS Antonio e Biagio and Cesare Arrigo, Alessandria, Italy

Frank Owusu-Ansah^1*, Jumana Afaghani^2*, Stanley Lee^3* and Justin Taylor, MD⁴

¹Eastern Virginia Medical School, Norfolk, VA
²University of Miami Miller School of Medicine, Miami, FL
³Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
⁴Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, Miami, FL

Natalia Baran, PhD, MD¹, Alessia Lodi, PhD^2*, Yogesh Dhungana, PhD^3*, Shannon RENEE Sweeney, PhD^4*, Pandey Renu, PhD^4*, Shelley Herbrich, PhD⁵, Fieke W Hoff, BSc^6*, Anna Skwarska, PhD^5,7*, Mecit Kaplan, MS^8*, Vinitha Mary Kuruvilla, MSc^5*, Antonio Cavazos, MSc^5*, Marc Warmoes, PhD^9*, Shanti Rojas-Sutterlin, PhD^10*, Andre Haman, PhD^10*, Diogo Troggian Veiga, PhD^11*, Ken Furudate, DDM, PhD^5*, Helen Ma, MS^5*, Karine Harutyunyan, PhD^5*, Wentao Yang^12*, Mihai Gagea, MD PhD^13*, Di Du, PhD^9*, May Daher¹⁴, Luciana Melo Garcia, MD^8*, Sujan Piya, PhD¹⁵, Vivian Ruvolo, MS^16*, Sriram Shanmugavelandy^17*, Ningping Feng, PhD^18*, Jason P Gay, MS^18*, Ondrej Havranek, MD, PhD¹⁹, Jared Henderson, MS^20*, Katarzyna Tomczak, PhD^21*, Marcin Kaminski, PhD^22*, Daniel Herranz, PharmD²³, Adolfo Ferrando, M.D., PhD^24*, Elias Jabbour, MD⁵, Maria E Di Francesco, PhD^18*, David T. Teachey, MD²⁵, Terzah M. Horton, MD, PhD²⁶, Katayoun Rezvani, MD, PhD⁸, Jun J. Yang, PhD¹², Steven M. Kornblau, MD¹⁶, Eric Davis, MD^20*, Koichi Takahashi, MD, PhD⁵, Michael Andreeff, MD, PhD¹⁶, Joseph R Marszalek, PhD^27*, Philip Lorenzi, PhD⁹, Jiyang Yu, Ph.D.^28*, Stefano Tiziani, PhD², Trang Hoang, PhD¹⁰ and Marina Konopleva, MD, PhD⁵

¹Department of Leukemia, MD Anderson Cancer Center, Houston, TX
²Department of Nutritional Sciences & Department of Pediatrics, Dell Medical School, The University of Texas at Austin, Austin, TX
³Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN
⁴Dell Pediatric Research Institute (DPRI), The University of Texas at Austin, Austin, TX
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Pediatric Oncology/ Hematology, University Medical Center Groningen, Groningen, Netherlands
⁷Department of Genetics, Medical University of Bialystok, Bialystok, Poland
⁸Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁹Dept. of Bioinformatics and Computational Biology and The Proteomics and Metabolomics Core Facility, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰IRIC - University of Montreal, Montreal, QC, Canada
¹¹The Jackson Laboratory for Genomic Medicine, Farmington, CT
¹²Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN
¹³Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁴Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Pearland, TX
¹⁶Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁷Abbvie, Lake Bluff, IL
¹⁸Institute for Applied Cancer Science and Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁹Institute of Biotechnology, Czech Academy of Sciences, Vestec, Czech Republic
²⁰Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²¹Department of Translational Molecular Pathology, UT M. D. Anderson Cancer Center, Houston, TX
²²Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN
²³Cancer Institute of NJ, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ
²⁴Department of Pathology, Columbia University Medical Center, New York, NY
²⁵Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
²⁶Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX
²⁷Institute for Applied Cancer Science & Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX
²⁸Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN

Jordy C.G. Van Der Zwet, MD^1*, Jessica G.C.A.M. Buijs-Gladdines^1*, Valentina Cordo', MSc^1*, Donna Debets, MSc^2*, Willem K. Smits^1*, Zhongli Chen, MSc^1*, Jelle Dylus^3*, Guido Zaman, PhD^3*, Maarten Altelaar, PhD^2*, Koichi Oshima, MD, PhD⁴, Beat Bornhauser^5*, Jean-Pierre Bourquin, MD, PhD⁵, Jan Cools, PhD⁶, Adolfo A. Ferrando, MD, PhD⁷, Josef Vormoor, MD, PhD¹, Rob Pieters, MD, PhD, MSc¹, Britta Julia Vormoor, MD^8* and Jules P.P. Meijerink, PhD¹

¹Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
²Bijvoet Center of Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht, Netherlands
³Netherlands Translational Research Center, Oss, Netherlands
⁴Columbia University Medical Center, New York, NY
⁵Department of Pediatric Oncology, Children’s Research Centre, University Children’s Hospital Zurich, Zurich, Switzerland
⁶Center for Cancer Biology, VIB-KU Leuven, Leuven, Belgium
⁷Institute for Cancer Genetics, Columbia University, New York, NY
⁸Princess Máxima Center for Pediatric Oncology, Utrecht, Utrecht, Netherlands

Martin G. Klatt, MD¹, Zhiyuan Yang, PhD^2*, Jianying Liu, PhD^2*, Tatyana Korontsvit, MD^1*, Sung Soo Mun^1*, Leila Peraro, PhD^1*, Thomas J. Gardner, PhD^1*, Christopher Bourne^1*, Megan M. Dacek^1*, Tao Dao, MD, PhD^1*, Cheng Liu, PhD^2* and David A. Scheinberg, MD, PhD^1,3

¹Memorial Sloan Kettering Cancer Center, New York, NY
²Eureka Therapeutics, Emeryville, CA
³Weill Cornell Medicine, New York, NY