-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

635. Myeloproliferative Syndromes: Basic Science: Poster II

Myeloproliferative Syndromes: Basic Science Program: Oral and Poster Abstracts
Type: Poster
Sunday, December 6, 2015: 6:00 PM-8:00 PM
Hall A, Level 2 (Orange County Convention Center)

Niccolò Bartalucci, PhD1,2*, Laura Calabresi, BiSci1,2*, Serena Martinelli, BiSci1,2*, Manjola Balliu, PhD1,2*, Jean-Luc Villeval, PhD3*, Francesco Annunziato, PhD1* and Alessandro M. Vannucchi1,2

1Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
2CRIMM-Centro Ricerca e Innovazione delle Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy
3INSERM, Institut Gustave Roussy, Villejuif, France

Titiksha Basu1*, Albert Gruender, Ph.D.2*, Christine Dierks, MD3* and Heike L Pahl, Ph.D.4

1Department of Hematology and Oncology, University of Freiburg, Freiburg, Germany
2Dept. of Hematology, Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany
3Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg im Breisgau, Germany
4Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany

Que T. Lambert1*, Stuart W. Ember2*, Muhammad Ayaz2*, Harshani R. Lawrence3*, Norbert Berndt2*, Steven Gunawan2*, Nicholas J. Lawrence2*, Ernst Schönbrunn2* and Gary W. Reuther1

1Department of Molecular Oncology, Moffitt Cancer Center and Research Institute, Tampa, FL
2Department of Drug Discovery, Moffitt Cancer Center and Research Institute, Tampa, FL
3Department of Drug Discovery, M, Tampa, FL

Susan C Rhodes, MBChB1,2*, Rafaella Gavriilidou1*, Mark W. Drummond, PhD, MD2*, Mhairi Copland, BSc (Hons) MB ChB PhD FRCP FRCPath1 and Helen Wheadon1*

1Paul O'Gorman Leukaemia Research Centre, University of Glasgow, Glasgow, United Kingdom
2Beatson West of Scotland Cancer Centre, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom

Asumi Yokota, PhD1*, Hideyo Hirai, MD, PhD1, Tsukimi Shoji1*, Taira Maekawa, MD, PhD1 and Keiko Okuda, MD, PhD2

1Department of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, Kyoto, Japan
2Department of Molecular Diagnostics and Therapeutics, Kyoto Prefectural Univ. of Med., Kyoto, Japan

Alexandra Keller, MSc1,2*, Barbara Peter, DVM1,2*, Johannes Zuber, MD, PhD3*, Philipp Bernhard Staber, MD, PhD2*, Peter Bettelheim, MD4*, Peter Valent, MD1,2 and Emir Hadzijusufovic, DVM1,2,5*

1Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria
2Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
3Research Institute of Molecular Pathology (IMP), Vienna, Austria
4First Medical Department, Elisabethinen Hospital, Linz, Austria
5Department of Companion Animals and Horses, Small Animal Clinic, Internal Medicine, University of Veterinary Medicine Vienna, Vienna, Austria

Simona Salati, PhD1*, Roberta Zini, PhD1*, Simona Nuzzo, PhD2*, Paola Guglielmelli, MD, PhD3*, Valentina Pennucci, PhD1*, Zelia Prudente1*, Samantha Ruberti1*, Sebastiano Rontauroli1*, Ruggiero Norfo, PhD1*, Elisa Bianchi, PhD1*, Costanza Bogani, PhD3*, Giada Rotunno, MSc3*, Tiziana Fanelli, MSc3*, Carmela Mannarelli, MSc3*, Vittorio Rosti4, Silvia Salmoiraghi, BSc5*, Daniela Pietra, PhD6*, Sergio Ferrari, MD, PhD7*, Giovanni Barosi, MD8, Alessandro Rambaldi, MD5, Mario Cazzola, MD9, Silvio Bicciato, PhD2*, Enrico Tagliafico2*, Alessandro M. Vannucchi, MD10 and Rossella Manfredini, PhD, BSc1*

1Centre for Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy
2Center for Genome Research, University of Modena and Reggio Emilia, Modena, Italy
3CRIMM-Centro Ricerca e Innovazione delle Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy
4Laboratory of Organ Transplantation, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
5Ospedali Riuniti di Bergamo, Bergamo, Italy
6Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
7Department of Life Science, University of Modena and Reggio Emilia, Modena, Italy
8Center for the Study of Myelofibrosis, Biotechnology Research Area, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
9Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Pavia, Italy
10University of Florence, Florence, Italy

Teresa L. Ramos1*, Luis Ignacio Sánchez-Abarca1*, Rosón Beatriz2*, Concepción Rodríguez Serrano1*, Alba Redondo1*, Rebeca Ortega1*, Ángel Hernández-Hernández3*, Sandra Muntión1*, Silvia Preciado1*, José Ramón González-Porras, MD4*, Fermín Sánchez-Guijo, MD1* and Consuelo Del Cañizo, MD1

1Servicio de Hematología, IBSAL-Hospital Universitario de Salamanca, Salamanca, Spain
2Centro de Investigación del Cáncer, Universidad de Salamanca, Salamanca, Spain
3Departamento de Bioquímica y Biología Molecular, Universidad de Salamanca, Salamanca, Spain
4Department of Hematology, Hospital Clínico de Salamanca, Salamanca, Spain

N. Scott Reading, Ph.D.1,2,3*, Josef T. Prchal, M.D.1,4,5, Ronald Hoffman, M.D.6 and Mohamed E Salama, M.D.1,2

1Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT
2Department of Pathology, University of Utah, Salt Lake City, UT
3Division of Hematology, School of Medicine, University of Utah, Salt Lake City, UT
4Division of Hematology, University of Utah, Salt Lake City, UT
5Department of Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT
6Tish Cancer Institute, Mount Sinai School of Medicine, New York, NY

Laura Villani, BS,1*, Rita Campanelli, BS1*, Gabriella Gaudioso, BS2*, Valentina Poletto, PhD1*, Elisa Bonetti, PhD1*, Paolo Catarsi, BS1*, Gabriela Fois, BS1*, Benedetta G Erba, PhD3*, Margherita Massa, PhD4*, Umberto Magrini, MD1*, Giovanni Barosi, MD1, Umberto Gianelli, MD2* and Vittorio Rosti, MD1

1Center for the Study of Myelofibrosis, Biotechnology Research Area, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
2University of Milano and IRCCS Ca' Granda, Ospedale Maggiore Policlinico Foundation, Milano, Italy
3IFOM, FIRC Institute of Molecular Oncology, Milano, Italy
4Biotechnology Research Area, IRCCS Policlinico San Matteo Foundation, Pavia, Italy

Hani Abdulkadir1*, Jennine Grootens2*, Matilda Kjellander1*, Eva Hellström Lindberg, MD, PhD3, Gunnar Nilsson, Professor2* and Johanna Ungerstedt, Associate Professor1*

1Department of Medicine Huddinge, Karolinska Institutet, and Hematology Center, Karolinska University Hospital, Stockholm, Sweden, Stockholm, Sweden
2Clinical Immunology and Allergy Unit, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden
3Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Sweden, Stockholm, Sweden

Tianjiao Zhang, MD1*, Xiaotang Ma, PhD1*, Bing Li, MD1*, Gang Huang, PhD2, Robert Peter Gale, MD, PhD, DSc3, Yue Zhang, MD4*, Zefeng Xu, MD4, Tiejun Qin1*, Josef T. Prchal, M.D.5 and Zhijian Xiao, MD4*

1MDS and MPN Centre, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
2Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
3Imperial College, London, United Kingdom
4State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
5Division of Hematology, University of Utah, Salt Lake City, UT

Arnold Kloos, PhD1*, Felicitas Thol, MD1, Sabrina Klesse1*, Alessandro Liebich1*, Arne Trummer, MD1*, Renate Schottmann1*, Rubén Trespando Jiménez1*, Gudrun Göhring, MD2*, Brigitte Schlegelberger, MD, PhD2, Arnold Ganser, M.D.1 and Michael Heuser, M.D.3

1Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
2Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
3Hematology, Hemostasis, Oncology and SCT, Hannover Medical School, Hannover, Germany

Carla AL Assaf1*, Petros Papadopoulos, PhD1*, Laura Guttierez, PhD2*, Sanne Smits1*, Carlos Graux, MD PhD3*, Jan Emmerechts, MD PhD4*, Els Lierman, PhD5*, Timothy Devos, MD PhD6*, Lucienne Michaux, MD PhD5* and Peter Vandenberghe, MD PhD5

1Dept of Human Genetics, KU Leuven, Leuven, Belgium
2Sanquin Research and Landsteiner Laboratory, AMC, Amsterdam, Netherlands
3Department of Hematology, CHU UcL Namur, Mont-Godinne, Belgium
4AZ -Jan, Brugge, Belgium
5Center for Human Genetics, University Hospitals Leuven, Leuven, Belgium
6Department of Hematology, University Hospitals Leuven, Leuven, Belgium

Sanja Prijic, PhD1,2*, Taghi Manshouri, PhD3*, Ying Zhang, MD, MS4*, Ivo Veletic, MD4, Xiaorui Zhang, BS5*, Joseph E Bove IV, BS4*, Zeev Estrov, MD6 and Srdan Verstovsek, MD7

1Department of Leukemia, The University of Texas, M. D. Anderson Cancer Center, Houston, TX
2University Hospital Center Zagreb, Zagreb, Croatia
3Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
4Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, TX
5Department of Leukemia, MD Anderson Cancer Center, Houston, TX
6Department of Leukemia, The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, TX
7Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

*signifies non-member of ASH