-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

632. Chronic Myeloid Leukemia: Therapy: Poster III

Chronic Myeloid Leukemia: Therapy Program: Oral and Poster Abstracts
Type: Poster
Monday, December 7, 2015: 6:00 PM-8:00 PM
Hall A, Level 2 (Orange County Convention Center)

Jacqueline Dickson, PhD1*, Nick Kennedy, MBBS MA Cantab FRACP2*, Leanne M. Cork, BSc (Hons)3*, Letizia Foroni, MD PhD FRCPath4*, Corinne A. Hedgley, BSc (Hons)3*, Mhairi Copland, BSc (Hons) MB ChB PhD FRCP FRCPath5, Tessa L. Holyoake, MD PhD5, Stephen G. O'Brien, BSc (Hons) PhD MBChB FRCP MRCPath3* and Bernard Ramashoye, PhD MRCP FRCPath1*

1Edinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, United Kingdom
2Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, United Kingdom
3Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom
4Department of Haematology, Imperial College London, Hammersmith Hospital, London, United Kingdom
5Paul O'Gorman Leukaemia Research Centre, University of Glasgow, Glasgow, United Kingdom

Stein-Erik Gullaksen, MSc1*, Jørn Skavland, PhD1*, Krzysztof Warzocha, MD, PhD2*, Sonia Gavasso, PhD3,4*, Vinko Tosevski, PhD5*, Noortje Thielen, MD, PhD6*, Jaroslava Voglova, MD7*, Augustin Ferrant, MD, PhD8, Werner Linkesch, MD9, Josef Thaler, MD10*, Alois Lang, MD11*, Jesper Stentoft12*, Tobias Gedde-Dahl, MD PhD13*, Henrik Hjorth-Hansen, MD, PhD14, Waleed Majeed, MD15*, Gregor Verhoef, MD, PhD16, Andrzej Hellmann, MD, PhD17, Georgi G. Mihaylov, MD, PhD18*, Claudia Dumrese, PhD5*, Frank Giles, MD MB19*, Andreas Hochhaus, MD20, Sieghart Sopper, PhD21*, Leif Stenke, MD, PhD22, Boris Labar, MD, PhD23, Jeroen Janssen, MD6, Kimmo Porkka, MD, PhD24, Gert J. Ossenkoppele, MD, PhD6, Satu Mustjoki, MD, PhD24, Dominik Wolf, MD25* and Bjorn T. Gjertsen, MD, PhD1,26

1Department of Clinical Science, University of Bergen, Bergen, Norway
2Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
3Department of Clinical Medicine, University of Bergen, Bergen, Norway
4Neuroimmunology Lab, Haukeland University Hospital, Bergen, Norway
5Flow Cytometry Facility, University of Zurich, Zurich, Switzerland
6Department of Hematology, VU University Medical Center, Amsterdam, Netherlands
74th Department of Internal Medicine - Haematology,, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
8Hematology, Cliniques Universitaires Saint-Luc, Brussels, Belgium
9Department of Hematology, Medical University of Graz, Auenbruggerplatz 25, Graz, Austria
10Department of Internal Medicine IV, Klinikum Wels-Grieskirchen, Wels, Austria
11Department of Internal Medicine, LKH Feldkirch, Feldkirch, Austria
12Department of Hematology, Aarhus University Hospital, Aarhus, Denmark
13Dept of Internal Medcine, Oslo University Hospital, Oslo, Norway
14Dept of Hematology, St Olavs Hospital, Trondheim, Norway
15Dept of hemato-oncology, Stavanger University Hospital, Stavanger, Norway
16Department of Hematology, University Hospitals Leuven, Leuven, Belgium
17Department of Hematology, University Clinical Center of Medical University of Gdansk, Gdansk, Poland
18Clinic for Hematology, University Hospital Sofia, Sofia, Bulgaria
19NMDTI, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
20Department of Hematology and Oncology, University Hospital Jena, Jena, Germany
21Internal Medicine V and Tyrolean Cancer Research Institute (TKFI), Medical University Innsbruck, Innsbruck, Austria
22Department of Medicine, Division of Hematology, Karolinska University Hospital, Stockholm, Sweden
23Dept. of Medicine, Div. of Hematology, University Hospital Center - Rebro, Zagreb, Croatia
24Hematology Research Unit Helsinki, University of Helsinki and Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
25Department of Internal Medicine III, Oncology, Hematology and Rheumatology, University Hospital Bonn, Bonn, Germany
26Department of Internal Medicine, Helse Bergen, Bergen, Norway

Pratik Deb, MBBS1, Uttam Nath, M.B.B.S., M.D., D.M.2*, Rajarshi Aich, M.B.B.S3*, Siddhartha Sankar Ray, M.B.B.S., M.D., D.M.4* and Prantar Chakrabarti, MBBS, MD, DM5*

1Dept. of Pathology and Laboratory Medicine, Rutgers Biomedical & Health Sciences, Newark, NJ
2Institution of Hematology and Transfusion Medicine, Medical College, Kolkata, Kolkata, India
3Medical College, Kolkata, Kolkata, India
4Institute of Hematology and Transfusion Medicine, Medical College, Kolkata, Kolkata, India
5Dept. of Hematology, N.R.S. Medical College, Kolkata, Kolkata, India

Alexander M. Labeit, MD PhD1*, Mhairi Copland, BSc (Hons) MB ChB PhD FRCP FRCPath2, Leanne M. Cork, BSc (Hons)3*, Corinne A. Hedgley, BSc (Hons)3*, Letizia Foroni, MD PhD FRCPath4*, Wendy L. Osborne, MBBS (Hons) MRCP FRCPath5*, Gemma Gills, MSc BSc (Hons)3*, Jane F. Apperley, MD4, Tessa L. Holyoake, MD PhD2, Ruth V. Bescoby, MSc BSc3*, Christopher Pocock6, Thomas Zwingers, MSc7*, Philippa Burnell8*, Jenny L. Byrne, PhD9*, John H. McCullough3*, John M. Goldman, DM FRCP FRCPath4, Richard E. Clark, MD10 and Stephen G. O'Brien, BSc (Hons) PhD MBChB FRCP MRCPath3*

1Health Economics and Decision Science, University of Sheffield, Sheffield, United Kingdom
2Paul O'Gorman Leukaemia Research Centre, University of Glasgow, Glasgow, United Kingdom
3Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom
4Department of Haematology, Imperial College London, Hammersmith Hospital, London, United Kingdom
5Northern Centre for Cancer Care, Freeman Hospital, The Newcastle upon Tyne Hospitals, Newcastle upon Tyne, United Kingdom
6East Kent Hospitals, Canterbury, United Kingdom
7Cros NT, Augsburg, Germany
8The Newcastle upon Tyne Hospitals, Newcastle upon Tyne, United Kingdom
9Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham, United Kingdom
10Department of Haematology, Royal Liverpool University Hospital, University of Liverpool, Liverpool, United Kingdom

Andreas Hochhaus, MD1, Jorge E. Cortes2*, Dong-Wook Kim3, Javier Pinilla-Ibarz4*, Philipp D. le Coutre5, Ronald Paquette6, Charles Chuah7, Franck E. Nicolini, MD, PhD8, Jane F. Apperley, MD9, H. Jean Khoury10, Moshe Talpaz11, Daniel J. DeAngelo12, Elisabetta Abruzzese13*, Delphine Rea14*, Michele Baccarani, MD15, Martin C. Muller16*, Carlo Gambacorti-Passerini17, Stephanie Lustgarten, PhD18*, Maureen Conlan18*, Victor M. Rivera18, Francois Guilhot19, Mochael W. Deininger20, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA21, Neil P. Shah22 and Hagop M. Kantarjian23

1Jena University Hospital, Jena, Germany
2Department of Leukemia, University of Texas M.D. Anderson Cancer Center, Houston, TX
3Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea
4Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
5Charité Universitätsmedizin Berlin, Berlin, Germany
6Ronald Reagan UCLA Medical Center, University of California, Los Angeles, CA
7Department of Hematology, Singapore General Hospital, Singapore, Singapore
8Centre Hospitalier Lyon Sud, Pierre-Bénite, France
9Haematology Department, Hammersmith Hospital (Imperial College Healthcare NHS Trust), London, United Kingdom
10Winship Cancer Institute of Emory University, Atlanta, GA
11Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI
12Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
13S. Eugenio Hospital, Tor Vergata University, Rome, Italy
14Hematology department, Hôpital Saint-Louis, Paris, France
15Institute of Hematology, University of Bologna, Bologna, Italy
16Universitätsmedizin Mannheim, Mannheim, Germany
17Azienda Ospedaliera San Gerardo/University of Milano-Bicocca, Monza, Italy
18ARIAD Pharmaceuticals, Inc., Cambridge, MA
19Inserm CIC 1402, CHU de Poitiers, Poitiers, France
20Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
21SA Pathology and South Australian Health and Medical Research Institute, University of Adelaide, Adelaide, Australia
22Department of Medicine, University of California at San Francisco, San Francisco, CA
23Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Dennis Dong Hwan Kim, MD/PhD1, Feras Alfraih, MD2,3, Tanya Adityan4* and Jeffrey H. Lipton, MD, PhD3

1Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
2Oncology Centre, King Faisal Hospital and Research Centre, Riyadh, Saudi Arabia
3Allogeneic Blood and Marrow Transplant Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada
4Princess Margaret Cancer Centre, Toronto, ON, Canada

Mohamed El Missiry, MD, MSc1*, Shady Adnan, MD, MSc2*, Hanna Rajala, MD, PhD3*, Ahmed Al-Samadi, DDS, PhD4*, Marja Ekblom5*, Berit Markevän, MD, PhD6*, Ingbritt Åstrand-Grundström5*, Maren Wold7*, Birgitte Ravn Juhl, MD, dr.med.sci8*, Ole Weis Bjerrum, MD, DMSc9*, Inger Haulin10*, Kimmo Porkka, MD, PhD11, Ulla Olsson-Strömberg12*, Henrik Hjorth-Hansen, MD, PhD13 and Satu Mustjoki, MD, PhD2,14

1Hematology Research Unit, University of Helsinki, Helsinki, Finland
2Hematology Research Unit Helsinki (HRUH), Department of Hematology, University of Helsinki and Helsinki University Central Hospital Comprehensive Cancer Center, Helsinki, Finland
3Department of Hematology, University of Helsinki and Helsinki University Central Hospital Comprehensive Cancer Center, Hematology Research Unit Helsinki (HRUH), Helsinki, Finland
4Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland
5Skåne University Hospital, Lund, Sweden
6Department of Hematology, Umeå University Hospital, Umeå, Sweden
7Department of Hematology, St Olavs Hospital, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
8Department of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
9Department of Hematology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
10Uppsala University Hospital, Department of Pathology, Uppsala, Sweden
11Hematology Research Unit Helsinki, University of Helsinki and Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
12Department of Hematology, Uppsala University Hospital, Uppsala, Sweden
13Dept of Hematology, St Olavs Hospital, Trondheim, Norway
14Department of Clinical Chemistry, University of Helsinki, Helsinki, Finland

Simona Bernardi1*, Andrea Di Palma2*, Mario Tiribelli, MD3*, Erika Codarin4*, Giuseppina Ruggeri5*, Maria Teresa Bochicchio6*, Michele Malagola2, Federica Cattina2*, Simone Perucca2*, Valeria Cancelli2*, Crisitina Skert2*, Gianantonio Rosti, MD7*, Fausto Castagnetti, PhD7, Luigi Caimi5*, Giuseppe Rossi8, Giovanni Martinelli7 and Domenico Russo2

1Unit of Blood Diseases and Stem Cells Transplantation, University of Brescia, Brescia, Italy
2Unit of Blood Diseases and Stem Cells Transplantation, University of Brescia, A.O. Spedali Civili of Brescia, Brescia, Italy
3Division of Hematology and Bone Marrow Transplantation, University Hospital, Udine, Italy
4Division of Hematology and Bone Marrow Transplantation, University Hospital of Udine, Udine, Italy
5Chair of Biochemistry, Department of Molecular and Translational Medicine, University of Brescia, Department of Laboratory, A.O. Spedali Civili of Brescia, Brescia, Italy
6Institute of Hematology, Bologna, Italy
7Department of Hematology and Oncological Sciences, Bologna, Italy
8Division of Hematology, A.O. Spedali Civili of Brescia, Brescia, Italy

Timothy P. Hughes, MD, MBBS, FRACP, FRCPA1, Francisco Cervantes2, Nelson Spector, MD, PhD3, Brian Leber, MD4, Susan Branford, PhD FFSc (RCPA)5,6, Tara A. Glynos, BS7*, Sandip Acharya, MSc8*, Darshan Dalal, MD, PhD, MPH7* and Jeffrey H. Lipton, MD, PhD9

1SA Pathology and South Australian Health and Medical Research Institute, University of Adelaide, Adelaide, Australia
2Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
3Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
4McMaster University, Hamilton, ON, Canada
5Department of Genetics and Molecular Pathology, SA Pathology, Centre for Cancer Biology, School of Medicine and School of Molecular and Biomedical Science, University of Adelaide, School of Pharmacy and Medical Science, University, Adelaide, Australia
6Centre for Cancer Biology, SA Pathology, University of Adelaide, Adelaide, Australia
7Novartis Pharmaceuticals Corporation, East Hanover, NJ
8Novartis Health Care Pvt. Ltd., Hyderabad, India
9Allogeneic Blood and Marrow Transplant Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada

Chatree Chai-Adisaksopha, MD1, Diep Calvin1* and Christopher M Hillis, MD, FRCPC2

1Department of Medicine, McMaster University, Hamilton, ON, Canada
2Department of Oncology, McMaster University, Hamilton, ON, Canada

Katia B.B. Pagnano, MD, PhD1, Paola Morelato Assunção, MD1*, Roberto Zullli1*, Marcia T Delamain, MD1*, Gislaine OLIVEIRA Duarte1*, Irene Lorand-Metze, MD, PhD2* and Carmino A De Souza Sr., MD, PhD1

1Hematology and Hemotherapy Center, University of Campinas, Campinas, Brazil
2Hematology and Hemotherapy Center, Department of Hematology, University of Campinas, Campinas, Brazil

Chiaki Nakaseko, MD, PhD1, Naoto Takahashi, MD, PhD, FJSIM2, Kaichi Nishiwaki, MD, PhD.3*, Hitoshi Ogasawara, MD, PhD.4* and Hisashi Wakita, MD5*

1Department of Hematology, Chiba University Hospital, Chiba, Japan
2Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan
3Oncology and Hematology, Jikei University Kashiwa Hospital, Kashiwa, Japan
4Department of Internal Medicine, Odate Municipal General Hospital, Odate, Japan
5Departmet of Hematology and Oncology, Japanese Red Cross Narita Hospital, Narita, Japan

Sieghart Sopper, PhD1*, Satu Mustjoki, MD, PhD2, Angelica Loskog, PhD3*, Bjorn T. Gjertsen, MD, PhD4, Guenther A. Gastl, MD5, Frank Giles, MD MB6*, Andreas Hochhaus, MD7, Gert J. Ossenkoppele, MD, PhD8, Kimmo Porkka, MD, PhD9 and Dominik Wolf, MD10*

1Internal Medicine V and Tyrolean Cancer Research Institute (TKFI), Medical University Innsbruck, Innsbruck, Austria
2Hematology Research Unit Helsinki (HRUH), Department of Hematology, University of Helsinki and Helsinki University Central Hospital Comprehensive Cancer Center, Helsinki, Finland
3Immunology, Genetics and Pathology, Uppsala University, Uppsale, Sweden
4Institute of Medicine, Hematology section, University of Bergen, Bergen, Norway
5Internal Medicine V, Haematology & Oncology, Innsbruck Medical University, Innsbruck, Austria
6NMDTI, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
7Klinik f. Innere Medizin II, Abt. für Hämatologie und internistische Onkologie, Universitätsklinikum Jena, Jena, Germany
8Department of Hematology, VU University Medical Center, Amsterdam, Netherlands
9Hematology Research Unit Helsinki, University of Helsinki and Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
10Internal Medicine III, Oncology, Hematology and Rheumatology, University Clinic Bonn, Bonn, Germany

Avi Leader, MD1,2*, Noam Benyamini, MD3*, Sabina De Geest, PhD RN4,5*, Juliet Dreyer, RN MA6*, Bronya Calvarysky, MSc Clin Pharm7*, Sara Gechler, PhD6*, Alina Amitai, PharmD8*, Osnat Jarchowsky-Dolberg, MD2,9*, Giora Sharf10*, Eric Tousset, M.Sc.11*, Opher Caspi, MD PhD2,12*, Martin Ellis, MD2,9*, Itai Levi, MD13, Anat Gafter-Gvili, MD2,6,14* and Pia Raanani, MD6,15

1Division of Hematology, Davidoff Center, Beilinson Hospital, Rabin Medical Center, Petah-Tikva, Israel
2Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
3Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel
4Institute of Nursing, University of Basel, Basel, Switzerland
5Health Services Research, KU Leuven, Leuven, Belgium
6Institute of Hematology, Davidoff Cancer Center, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
7Department of Pharmacy, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
8Department of Pharmacy, Meir Medical Center, Kfar Saba, Israel
9Hematology Institute and Blood Bank, Meir Medical Center, Kfar Saba, Israel
10Israeli CML Patients Organization, Netanya, Israel
11MWV Healthcare, Visé, Belgium
12Integrative medicine and Cancer Survivorship Program; Davidoff Cancer Center, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
13Hematology Department, Soroka University Medical Center, Faculty of Medicine, Ben-Gurion University of the Negev, Beer Sheva, Israel
14Department of Medicine A, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
15Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Naoto Takahashi, MD, PhD, FJSIM1, Tetsuzo Tauchi, M.D, Ph.D2*, Kunio Kitamura, MD, PhD3*, Koichi Miyamura, MD, PhD4, Yoshio Saburi, MD, PhD5*, Yasuhiko Miyata, MD, PhD6, Yoshihiro Hatta7, Fumihiko Kimura, MD8, Satoru Takada, M.D.9, Tetsuya Fukuda, MD, PhD10, Katsumichi Fujimaki11*, Maho Ishikawa12*, Itaru Matsumura, MD, PhD13, Noriko Usui, M.D., Ph D14, Kensuke Usuki, MD, Ph.D.15*, Yukio Kobayashi, MD, PhD16 and Tomoki Naoe, MD, Ph.D.17

1Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan
2Department of Hematology, Tokyo Medical University, Tokyo, Japan
3Division of Hematology, Ichinomiya Municipal Hospital, Ichinomiya, Japan
4Department of Hematology, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan
5Department of Hematology, Oita Prefectural Hospital, Oita, Japan
6National Hospital Organization, Nagoya Medical Center, Nagoya, Japan
7Department of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan
8Division of Hematology, National Defense Medical College, Tokorozawa, Japan
9Leukemia Research Center, Saiseikai Maebashi Hospital, Maebashi, Japan
10Hematology, Tokyo Medical and Dental University, Tokyo, Japan
11Hematology/Immunology, Fujisawa City Hospital, Fujisawa, Japan
12Department of Hematology,, Saitama Medical University International Medical Center, Saitama, Japan
13Hematology, Kinki University Hospital, Osaka, Japan
14Department of Clinical Oncology/ Hematology, the Jikei University School of Medicine, Tokyo, Japan
15Deptartment of Hematology, NTT Medical Center Tokyo, Tokyo, Japan
16National Cancer Center Hospital, Tokyo, Japan
17National Hospital Organization Nagoya Medical Center, Nagoya, Japan

Ziyuan Lu1*, Na Xu, MD1*, Xuan Zhou, MD1*, Guanlun Gao2*, Lin Li1*, Jixian Huang1*, Yuling Li1*, Qisi Lu1*, Bolin He1*, Chengyun Pan1* and Liu Xiaoli, MD1

1Department of Hematology, NanFang Hospital, Southern Medical University, Guangzhou, China
2Guangzhou red cross hospital, Guangzhou, China

Nurgul Ozgur Yurttas, MD*, Sevil Sadri, MD*, Dilek Keskin, MD*, Selin Berk, MD*, Isil Erdogan Oztunali, MD*, Fevzi Firat Yalniz, MD*, Ayse Salihoglu, MD*, Ahmet Emre Eskazan, MD, M. Cem Ar, MD, PhD*, Seniz Ongoren Aydin, MD*, Zafer Baslar, MD*, Yildiz Aydin, MD* and Teoman Soysal, MD*

Department of Internal Medicine, Division of Hematology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey

Roberto Latagliata1*, Massimo Breccia, MD2*, Ida Carmosino3*, Federico Vozella4*, Federico De Angelis4*, Chiara Montagna4*, Maria Lucia De Luca4*, Gioia Colafigli5*, Luisa Quattrocchi4*, Giovanna Loglisci4*, Angela Romano4*, Paola Volpicelli4*, Daniela Diverio, PhD3*, Marco Mancini4* and Giuliana Alimena3

1Dept. of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Rome, Italy
2HEMATOLOGY SAPIENZA UNIVERSITY, ROME, Italy
3Department of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Italy
4Department of Cellular Biotechnologies and Hematology, University Sapienza, Rome, Italy
5Cellular Biotechnologies and Hematology, University La Sapienza, Rome, Italy

Franck E. Nicolini, MD, PhD1,2,3, Mael Heiblig, MD1*, Stéphane Morisset, Stat1*, Denis Caillot4*, Valérie Coiteux, MD2,5*, Aude Charbonnier, MD2,6*, Françoise Huguet, MD2,7*, Viviane Dubruille, MD2,8*, Gabriel Etienne, MD, PhD2,9*, Pascal Lenain, MD2,10*, Francois Guilhot, MD2,11, Laurence Legros, MD2,12*, Philippe Rousselot, MD, PhD2,13*, Shanti Amé, MD2,14*, Rémy DeFrance, MD15*, Jeremy Ruby, CRA1,2*, Francois-Xavier Mahon, MD, PhD, Professor2,16* and Delphine Rea2,17*

1Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite, France
2Fi-LMC group, Pessac, France
3INSERM U1052, Centre de Recherche en Cancérologie de Lyon, Lyon, France
4Hematology department, CHU du Bocage, Dijon, France
5Hematology department, Hôpital Claude Huriez, Lille, France
6Hematology department, Institut Paoli Calmettes, Marseille, France
7Hematology department, Institut universitaire du cancer de Toulouse, Toulouse, France
8Department of Hematology, Nantes University Hospital, Nantes, France
9Hematology department, Institut Bergonié, Bordeaux, France
10Hematology department, Centre Henri Becquerel, Rouen, France
11Hematology department, Inserm CIC 1402, CHU de Poitiers, Poitiers, France
12Hematology department, Hopital Archet 1, CHU Nice, Nice, France
13Hematology Department, Hôpital André Mignot, Versailles, France
14Hematology department, Hôpital Civil , CHU Strasbourg, Strasbourg, France
15Ariad Pharmaceuticals France, Paris, France
16Laboratory of Hematology, Hôpital haut Lévêque, Pessac, France
17Hematology department, Hôpital Saint-Louis, Paris, France

Delphine Rea, MD, PhD1*, Gianantonio Rosti, MD2*, Nicholas C.P. Cross, PhD3, Andrzej Hellman, MD, PhD4*, Dietger Niederwieser, MD5, Ester Pungolino, MD6*, Franca Falzetti, MD7, Patrizia Pregno, MD8*, Ester Maria Orlandi, MD9*, Antonio Medina Almeida10*, Arpad Illes, MD, PhD11*, Cristalina Fernandez12*, Luca Dezzani13*, Angela Pellegrino14*, Chiara Costantini14*, Claudia Walasek14*, Giuseppe Saglio15, Juan Luis Steegmann, MD16 and Michele Baccarani17

1Adult hematology department, Hôpital Saint-Louis, APHP, Paris, France
2Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
3Wessex Regional Genetics Laboratory, University of Southampton, Salisbury, United Kingdom
4Medical University of Gdańsk, Gdańsk, Poland
5Hematology and Oncology, University of Leipzig, Leipzig, Germany
6Niguarda Cà Granda Hospital, Milan, Italy
7University of Perugia, Perugia, Italy
8Department of Hematology, San Giovanni Battista University Hospital, TORINO, Italy
9Dept of Oncology-Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
10Instituto Português de Oncologia de Lisboa,, Serviço de Hematologia,, Lisbon, Portugal
11Department of Hematology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
12Hematology Department,, ICO Girona-Hospital, Girona, Spain
13NOVARTIS ONCOLOGY ITALY, Origgio Varese, Italy
14Novartis Oncology Region Europe, Origgio, Italy
15University of Turin, Orbassano, Italy
16Hematology Dpt. IIS-IP, Hospital Universitario de la Princesa, Madrid, Spain
17Institute of Hematology, University of Bologna, Bologna, Italy

Jorge E. Cortes1, Tim H. Brümmendorf, MD2,3, Hagop M. Kantarjian, MD1, Dong-Wook Kim, MD, PhD4, Philippe Schafhausen, MD2*, Sashi Nadanaciva, D Phil5*, Nathalie Bardy-Bouxin, PhD6*, Mark Shapiro, MD7, Eric Leip, PhD7*, Jeffrey H. Lipton, MD, PhD8 and Carlo Gambacorti-Passerini, MD9

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2University Cancer Center Hamburg, Hubertus Wald Tumor Center, Hamburg, Germany
3RWTH Aachen University Hospital, Aachen, Germany
4Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea
5Pfizer Inc, Groton, CT
6Global Research and Development, Pfizer, Paris, France
7Pfizer Inc, Cambridge, MA
8Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada
9University of Milano-Bicocca, Monza, Italy

Pascal Vannuffel, PhD1*, Barbara Cauwelier, PhD, MD2*, Céline De Rop1* and Friedel Nollet, PhD3*

1Molecular Biology, Institut de Pathologie et de Génétique, Gosselies, Belgium
2Department of Hematology, AZ St Jan AV, Bruges, Belgium
3Laboratory Medecine, AZ Sint-Jan, Bruges, Belgium

Hana Zizkova1*, Eliska Motlova2*, Karla Zemanova1*, Hana Klamova1,3*, Lenka Hovorkova4*, Jan Zuna4, Jan Zach5*, Susanne Saussele6, Francois-Xavier Mahon7 and Katerina Machova Polakova1,3*

1Institute of Hematology and Blood Transfusion, Prague, Czech Republic
2University of Chemistry and Technology, Prague, Czech Republic
3Institute of Clinical and Experimental Hematology, First Faculty of Medicine, Charles University, Prague, Czech Republic
4CLIP, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and UH Motol, Prague, Czech Republic
5Institute of Hematology and Blood Transfusion, Pargue, Czech Republic
6III. Medizinische Klinik, Universitätsmedizin Mannheim, Universität Heidelberg, Mannheim, Germany
7Hôpital Haut Lévêque, Centre Hospitalier Universitaire, Bordeaux, France

Brian Gabriel Jiang1*, Dong-Wook Kim, M.D.2, Lee-Yung Shih, MD3, Charles Chuah4,5, Hein Than, MD4*, Ming-Chung Kuo, MD6*, HuiHua Li, PhD7*, John Carson Allen Jr., PhD8*, Lionel KY See9*, Bernard KC Yap9* and Yeow-Tee Goh, MBBS, MMed4,9

1Duke University School of Medicine, Durham, NC
2Department of Haematology, St. Mary’s Hospital, Seoul, South Korea
3Department of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, College of Medicine Chang Gung University, Taipei, Taiwan
4Department of Hematology, Singapore General Hospital, Singapore, Singapore
5Cancer & Stem Cell Biology Signature Research Program, Duke-NUS Graduate Medical School, Singapore, Singapore
6Chang Gung Memorial Hospital-Linkou and Chang Gung University, Taoyuan, Taiwan
7Health Services Research, Singapore, Singapore, Singapore
8Centre For Quantitative Medicine, Duke-NUS Graduate Medical School, Singapore, Singapore
9Duke-NUS Graduate Medical School, Singapore, Singapore

H Jean Khoury, Leonard T Heffner Jr., MD, Martha Arellano, MD, Anand P Jillella, MD, Vamsi K Kota, MD and Elliott F. Winton, MD

Winship Cancer Institute of Emory University, Atlanta, GA

Massimo Breccia, MD1*, Fausto Castagnetti, MD/PhD2, Gabriele Gugliotta, MD/PhD2*, Bruno Martino, MD3*, Giuseppe Rossi, MD4, Angelo Michele Carella5, Fabio Stagno, MD/PhD6, Diamante Turri, MD7*, Paolo Avanzini, MD8*, Elena Trabacchi9*, Ivana Pierri, MD10*, Mario Tiribelli, MD11*, Alessandro Isidori, M.D. PhD12, Marzia Salvucci13*, Silvana Capalbo14, Anna Merli15*, Luciano Levato, MD16*, Gianni Binotto17*, Elena Maino18*, Serena Rupoli, MD19*, Fabrizio Pane, MD20, Giuseppe Saglio21, Michele Baccarani22, Giuliana Alimena23 and Gianantonio Rosti, MD2*

1Chair of Hematology, "Sapienza" University, Roma, Italy
2Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
3Hamatology Dept., Ospedali Riuniti Bianchi Melacrino Morelli, Reggio Calabria, Italy
4Department of Hematology, Spedali Civili di Brescia, Brescia, Italy
5Division of Hematology 1, IRCCS A.O.U. San Martino IST, Genova, Genova, Italy
6Section of Hematology, A.O.U. Policlinico, Catania, Italy
7Section of Hematology, A.O. Cervello, Palermo, Italy
8Hematology, S.Maria Nuova Hospital, Reggio Emilia, Italy
9Guglielmo da Saliceto Hospital, Piacenza, Italy
10Hematology Clinic, IRCSS AOU S.Martino-IST, University of Genova, Genova, Italy
11Division of Hematology and BMT, Department of Experimental and Clinical Medical Sciences, Azienda Ospedaliero-Universitaria di Udine, Udine, Italy
12Hematology and Stem Cell Transplant Center, AORMN Hospital, Pesaro, Italy
13S. Maria delle Croci Hospital, Ravenna, Italy
14Hematology, Ospedali Riuniti - Azienda Ospedaliero Universitaria, Foggia, Italy
15Hematology, Rimini, Italy
16Section of Hematology, A.O. Pugliese-Ciaccio, Catanzaro, Italy
17Department of Medicine, Hematology and Clinical Immunology, Padua School of Medicine, Padova, Italy
18Hematology Unit, Ospedale Dell'Angelo, Venezia-Mestre, Venezia-Mestre, Italy
19Haematology Clinic, Ospedali Riuniti di Ancona, Ancona, Italy
20Department of Biochemistry and Medical Biotechnologies, Federico II University, Napoli, Italy
21Dept. of Clinical and Biological Sciences, University of Turin, Orbassano-Torino, Italy
22Institute of Hematology, University of Bologna, Bologna, Italy
23Hematology, Sapienza University, Rome, Italy

Michael Lauseker, PhD1*, Joerg Hasford1*, Susanne Saussele2, Ruediger Hehlmann, MD2 and Markus Pfirrmann1*

1Institut für medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität, München, Germany
2III. Medizinische Klinik, Universität Heidelberg, Medizinische Fakultät, Mannheim, Germany

Jesus G. Berdeja, MD1, Michael Heinrich2, Shaker Dakhil, MD, FACP3, Stuart L. Goldberg, MD4, Martha Wadleigh, MD5, Rosalind Catchatourian, MD6, Philip Kuriakose, MD7, Jorge E. Cortes, MD8, Jerald P. Radich9, David A. Rizzieri, MD10, Gaetano Bonifacio, MD11*, Ilva Dautaj11*, Ghulam Warsi, PhD11* and Michael J. Mauro, MD12

1Sarah Cannon Research Institute, Nashville, TN
2Knight Cancer Institute, Oregon Health and Science University, Portland, OR
3Cancer Center of Kansas, Wichita, KS
4Division of Leukemia, John Theurer Cancer Center of Hackensack University Medical Center, Hackensack, NJ
5Dana-Farber Cancer Institute, Boston, MA
6Cook County Health and Hospitals System, Chicago, IL
7Henry Ford Health System, Detroit, MI
8Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
9Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
10Duke University School of Medicine, Durham, NC
11Novartis Pharmaceuticals Corporation, East Hanover, NJ
12Memorial Sloan Kettering Cancer Center, New York, NY

Paolo Vigneri, MD/PhD1*, Fabio Stagno, MD/PhD2, Stefania Stella, PhD3*, Alessandra Cupri, MD4*, Stefano Forte, PhD5*, Michele Massimino, PhD3*, Agostino Antolino, MD6*, Clementina Caracciolo, MD7*, Laura Nocilli, MD8*, Stefana Impera, MD9*, Caterina Musolino10*, Diamante Turri, MD11*, Mario Russo, MD12*, Carmela Anna Maria Tomaselli, MD13*, Michele Rizzo, MD14*, Maurizio Musso, MD15*, Fortunato Morabito, MD16*, Luciano Levato, MD17*, Livia Manzella, MD/PhD3*, Martin C Mueller, MD18*, Andreas Hochhaus, MD19 and Francesco Di Raimondo, MD/PhD4

1Dep. Clinical and Experimental Medicine, University of Catania Medical School, Catania, Italy
2Section of Hematology, A.O.U. Policlinico, Catania, Italy
3Dept. Clinical and Experimental Medicine, University of Catania Medical School, Catania, Italy
4Section of Hematology, A.O.U. Policlinico "Vittorio Emanuele", Catania, Italy
5IOM Ricerca srl, Viagrande (CT), Italy
6Department of Transfusional Medicine, SIMMT, Maria Paternò-Arezzo Hospital, Ragusa, Italy
7Section of Hematology, A.O.U. Policlinico "Paolo Giaccone", Palermo, Italy
8Section of Hematology, A.O. Papardo, Messina, Italy
9Section of Hematology, A.R.N.A.S. Garibaldi Nesima, Catania, Italy
10Section of Hematology, A.O.U. Policlinico, Messina, Italy
11Section of Hematology, A.O. Cervello, Palermo, Italy
12Section of Hematology, A.O. San Vincenzo, Taormina (ME), Italy
13Section of Hematology, A.R.N.A.S. Civico, Palermo, Italy
14Section of Hematology, A.O. Sant'Elia, Caltanissetta, Italy
15Section of Hematology, Casa di Cura "La Maddalena", Palermo, Italy
16Section of Hematology, A.O. L'Annunziata of Cosenza, Cosenza, Italy
17Section of Hematology, A.O. Pugliese-Ciaccio, Catanzaro, Italy
18III. Med. Klinik, Universitätsmedizin Mannheim, Mannheim, Germany
19Department of Haematology and Medical Oncology, Department of Internal Medicine II, University Hospital Jena, Jena, Germany

Ellen K. Ritchie, MD1, Rosalind Catchatourian, MD2, Rebecca B. Klisovic, MD3, Michael W Deininger, MD, PhD4, Harry P. Erba, MD, PhD5*, Jerald P. Radich6, Michael R. Savona, MD7, Ghulam Warsi, PhD8*, Carole S. Paley8*, Ilva Dautaj8*, Felice P. Lin, PharmD8* and Michael J. Mauro, MD9

1Division of Hematology / Oncology, Weill Cornell Medical College, New York, NY
2Cook County Health and Hospitals System, Chicago, IL
3Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
4The University of Utah, Salt Lake City, UT
5University of Alabama at Birmingham and UAB Comprehensive Cancer Center, Birmingham, AL
6Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
7Vanderbilt University Medical Center, Nashville, TN
8Novartis Pharmaceuticals Corporation, East Hanover, NJ
9Memorial Sloan Kettering Cancer Center, New York, NY

Elza Lomaia, MD, PhD1*, Andrey Zaritskey, MD2*, Vasily Shuvaev, MD3, Irina Martynkevich, MD, PhD3*, Mikhail Fominykh, MD3, Ekaterina Ovsyannikova, MD2*, Natalia Lazorko, MD2*, Natalia Matyuhina, MS2*, Pavel Butylin, PhD2*, Elena Machyulaitene, MD4*, Evgenia Salamatova, MD2* and Kudrat Abdulkadyrov, MD, PhD3*

1Almazov Federal medical research center, Sant-Petersburg, Russia
2Almazov Federal medical research center, Saint-Petersburg, Russia
3Russian Research Institute of Hematology and Transfusiology, Saint Petersburg, Russia
4Pavlov First Saint-Petersburg state medical university, Saint-Petersburg, Russia

Kazunori Murai, MD, PhD1,2, Kohei Yamaguchi, MD3*, Shigeki Ito, MD, PhD4, Tomoaki Akagi5*, Kazuei Ogawa, MD, PhD6*, Inomata Mitsue7*, Kuniaki Meguro8*, Reiko Watanabe, MD, PhD9*, Takuto Miyagishima, M.D., Ph.D.10*, Kentaro Wakasa11*, Motohiro Shindo, MD, PhD12*, Yasuhiko Tsukushi, MD, PhD1*, Kohmei Kubo, M.D., Ph.D.13*, Koji Oba, PhD14,15*, Junichi Sakamoto, MD, PhD16* and Yoji Ishida, M.D., Ph.D.1

1Division of Hematology and Oncology, Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Japan
2Iwate Prefectural Central Hospital, Morioka, Japan
3Aomori Prefectural Central Hospital, Aomori City, Japan
4Division of Clinical Oncology, Iwate Medical University, School of Medicine, Morioka, Japan
5Aomori Prefectural Central Hospital, Aomori, Japan
6Department of Cardiology and Hematology, Fukushima Medical University, Fukushima, Japan
7National Hospital Organization Sendai Medical Center, SENDAI, Japan
8National Hospital Organization Sendai Medical Center, Sendai, Japan
9Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan
10Japan Labour Health and Welfare Organization, Kushiro Rosai Hospita, Kushiro, Japan
11Hokkaido P.W.F.A.C. Obihiro-Kosei General Hospital, Obihiro, Japan
12Division of Gastroenterology and Hematology/Oncology, Asahikawa Medical University, Asahikawa, Japan,, Asahikawa, Japan
13Aomori Prefectural Central Hospital, Aomoi, Japan
14Department of Biostatistics, School of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Tokyo, Japan
15Interfaculty Initiative in Information Studies, The University of Tokyo, Tokyo, Tokyo, Japan
16Tokai Central Hospital, Kakamigahara, Japan

Sung-Eun Lee, M.D.1,2*, Soo Young Choi2*, Jae-Yong Kwak3, Hawk Kim4, Jeong-A Kim, MD, PhD5, Young Rok Do6, Hyeoung Joon Kim7, Joon Seong Park8, Joo Seop Chung, MD, PhD9, Ho-Jin Shin9, Sung-Hyun Kim10, Dae-Young Kim, MD, PhD11*, Udomsak Bunworasate12, Chul Won Choi13*, Narcisa Sonia Cornejo Comia14*, Dae Young Zang15*, Sukjoong Oh16, Saengsuree Jootar17, Ary Harryanto Reksodiputro18*, Won Sik Lee19, Yeung-Chul Mun20, Jee Hyun Kong21*, Priscilla B. Caguioa22*, Jinny Park23, Chul Won Jung24 and Dong-Wook Kim2,25

1Department of Hematology, Catholic Blood and Marrow Transplantation Center, Cancer Research Institute, Seoul St. Mary’s hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
2Cancer Research Institute, The Catholic University of Korea, Seoul, South Korea
3Chonbuk National University Medical School & Hospital, Jeonju, South Korea
4Ulsan University Hospital, Ulsan, South Korea
5Hematology, St. Vincent Hospital, The Catholic University of Korea, Seoul, South Korea
6Dongsan Medical Center, Keimyung University, Daegu, South Korea
7Chonnam National University,Hwasun Hospital, Hwasun, South Korea
8Ajou University Hospital, Suwon, South Korea
9Pusan National University Hospital, Pusan, South Korea
10Dong-A University Medical Center, Busan, South Korea
11Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
12King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand
13Korea University, Guro Hospital, Seoul, South Korea
14Mary Mediatrix Medical Center, Batangas, Philippines
15Hallym University Sacred Heart Hospital, Anyang, South Korea
16Kangbuk Samsung Hospital, Seoul, South Korea
17Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
18Rumah Sakit Dr. Cipto Mangunkusumo Hospital, Jakarta, South Korea
19Inje University Busan Paik Hospital, Busan, South Korea
20Ewha Womans University Mokdong Hospital, Seoul, South Korea
21Wonju Severance Christian Hospital,, Wonju, South Korea
22St. Luke’s Medical Center, Manila, Philippines
23Gachon University Gil Medical Center, Incheon, South Korea
24Samsung Medical Center, Seoul, South Korea
25Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea

Andreas Hochhaus, MD1, Francois-Xavier Mahon2, Philipp le Coutre3*, Daniel Coriu4*, Ljubomir Petrov, MD, PhD5*, Gert J. Ossenkoppele, MD, PhD6, Nicholas C.P. Cross, PhD7, Martin C. Müller, MD8*, Delphine Rea, MD, PhD9*, Juan Luis Steegmann, MD10, Fausto Castagnetti, MD/PhD11, Andrzej Hellmann, MD, PhD12, Gianantonio Rosti, MD13*, Norbert Gattermann, MD14, Maria Liz Paciello Coronel15*, Jose Valentin Garcia Gutierrez16*, Viviana Tubazio17*, Angela Pellegrino17*, Luca Dezzani17* and Francis J. Giles, MB, MD, FRCPI, FRCPath18

1Department of Hematology and Oncology, University Hospital Jena, Jena, Germany
2Hematology Laboratory, Bordeaux University,Bordeaux Hospital, INSERM 1035, BORDEAUX, France
3Charité - University of Medicine Berlin Campus Virchow, Berlin, Germany
4Institutul Clinic Fundeni, Bucharest, Romania
5Ion Chiricuta Instititute of Oncology, Cluj-Napoca, Romania
6Department of Hematology, VU University Medical Center, Amsterdam, Netherlands
7Wessex Regional Genetics Laboratory, University of Southampton, Salisbury, United Kingdom
8Universitätsmedizin Mannheim, Universität Heidelberg, Mannheim, Germany
9Adult hematology department, Hôpital Saint-Louis, APHP, Paris, France
10Hematology Dpt. IIS-IP, Hospital Universitario de la Princesa, Madrid, Spain
11Bologna University School of Medicine, Bologna, Italy
12Department of Hematology, Medical University of Gdansk, Gdansk, Poland
13Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
14Dept. of Hematology, Oncology, and clinical Immunology, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany
15Servicio de Hematología-Hemoterapia, Madriad, Spain
16Servicio de Hematología y Hemoterapia, Madriad, Spain
17Novartis Oncology Region Europe, Origgio, Italy
18Institute for Drug Development, Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, TX

*signifies non-member of ASH