-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

631. Chronic Myeloid Leukemia: Biology and Pathophysiology, excluding Therapy: Poster II

Chronic Myeloid Leukemia: Biology and Pathophysiology, excluding Therapy Program: Oral and Poster Abstracts
Type: Poster
Sunday, December 6, 2015: 6:00 PM-8:00 PM
Hall A, Level 2 (Orange County Convention Center)

Tun Kiat Ko, PhD1*, Xin Xuan Sheila Soh1*, Willie Yu, PhD1*, Peter S. Winter2*, Thushangi Pathiraja, PhD3*, Asif Javed, PhD4*, Simeen Malik, PhD1*, Joanna H.J. Tan3*, Charles Chuah, MD, PhD1,5, Naoto Takahashi, M.D., Ph.D.6, Ravi Bhatia, MD7, Wee Joo Chng, MD, PhD8,9, Peter Valent, MD10,11, Sabine Cerny-Reiterer, DVM10,11*, King Pan Ng, PhD8*, Chandana Tennakoon, PhD4*, Qiangze Hoi4*, Peiyong Guan4*, Audrey S.M. Teo3*, Wah Heng Lee, PhD4*, Patrick Tan, MD, PhD8,12,13*, Win Kin Sung, PhD4*, Pauline Ng, PhD4*, Axel Hillmer, PhD3*, Kris C. Wood, PhD2*, Steve Rozen, PhD1* and S. Tiong Ong, MD1,14

1Cancer & Stem Cell Biology Signature Research Program, Duke-NUS Graduate Medical School, Singapore, Singapore
2Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC
3Cancer Therapeutics & Stratified Oncology, Genome Institute of Singapore, Singapore, Singapore
4Computational & Systems Biology, Genome Institute of Singapore, Singapore, Singapore
5Singapore General Hospital, Singapore, Singapore
6Department of Hematology, Nephrology and Rheumatology, Akita University, Akita, Japan
7Department of Hematopoietic Stem cell and Leukemia Research, City of Hope, Duarte, CA
8Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
9Department of Haematology-Oncology, National University Cancer Institute of Singapore, Singapore, Singapore
10Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
11Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria
12Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore
13Genome Institute of Singapore, A*STAR, Singapore, Singapore
14Department of Haematology, Singapore General Hospital, Singapore, Singapore

Haobin Ye1,2*, Nabilah Khan, PhD1*, Marlene Balys3*, John M. Ashton, PhD3*, Biniam Adane1* and Craig T Jordan, PhD1

1Division of Hematology, University of Colorado School of Medicine, Aurora, CO
2Department of Pathology, University of Rochester, Rochester, NY
3James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY

Robert Orlowski, MD1, Alexander Huang1, Mercy Gohil2*, James Mangan, MD, PhD1, Marissa Vignali, PhD3*, Ryan O Emerson, PhD3, Harlan Robins, PhD3, Erik Yusko, PhD3*, Martha S Jordan, PhD4*, Martin Carroll, MD5, D. Gary Gilliland, MD, PhD6 and Elizabeth O Hexner, MD1

1Division of Hematology-Oncology, University of Pennsylvania, Philadelphia, PA
2Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA
3Adaptive Biotechnologies Corp., Seattle, WA
4Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
5Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
6Division of Hematology/Oncology, Fred Hutchinson Cancer Center, Seattle, WA

Cesarina Giallongo1*, Nunziatina L Parrinello1*, Daniele Tibullo, Ph.D1*, Piera La Cava1*, Alessandra Romano, MD, PhD1*, Annalisa Chiarenza2*, Fabio Stagno, MD, PhD1, Paolo Vigneri, MD/PhD3*, Giuseppe A Palumbo4*, Francesco Di Raimondo, MD/PhD5 and Claudia Bellofiore1*

1Division of Haematology, AOU, Catania, Italy
2Division of Hematology, Ferrarotto Hospital, Catania, Italy
3Dep. Clinical and Experimental Medicine, University of Catania Medical School, Catania, Italy
4Division of Haematology, AOU "Policlinico - Vittorio Emanuele", University of Catania , Catania , Italy., Catania, Italy
5Section of Hematology, A.O.U. Policlinico "Vittorio Emanuele", Catania, Italy

Philippe Guardiola, MD1, Corentin Orvain2*, Nick C.P. Cross, PhD3, Martine Gardembas, MD2*, Marc Spentchian, MD4*, Estelle Pedrono, PhD1*, Diane Lambert, PhD1*, Anne Coutolleau1*, Anne Bouvier, MD5*, Odile Blanchet, MD PhD6*, Nicole Piard, MD7*, Norbert Ifrah, MD, PhD2, Frank Giles, MD, MB, FRCPI, FRCPath8, Andreas Hochhaus, MD9, Jerald P. Radich, MD10 and Philippe Rousselot, MD, PhD11*

1Genomic Platform, University Hospital, Angers, France
2Hematology Department, University Hospital, Angers, France
3Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, United Kingdom
4Service de Biologie Médicale, Hôpital André Mignot, Versailles, France
5Hematology Laboratory, University Hospital, Angers, France
6Centre de Ressources Biologiques, University Hospital, Angers, France
7EFS Pays de la Loire, Angers, France
8NMDTI, Northwestern University, Chicago, IL
9Department of Hematology and Oncology, University Hospital Jena, Jena, Germany
10Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
11Hematology Department, Hôpital André Mignot, Versailles, France

Seiichi Okabe, MD, PhD*, Tetsuzo Tauchi, M.D, Ph.D*, Yuko Tanaka, M.D, Ph.D*, Juri Sakuta, MD, PhD* and Kazuma Ohyashiki, MD, PhD

Department of Hematology, Tokyo Medical University, Tokyo, Japan

Jueqiong WANG, PhD1,2*, Chung Hoow Kok, PhD1,2*, Tamara M Leclercq, PhD1,2*, Verity A Saunders, BSc (Hons)2*, Richard J D'Andrea, PhD3,4*, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA5,6,7 and Deborah L White, PhD, FFSc (RCPA)1,2,6

1School of Medicine, University of Adelaide, Adelaide, Australia
2Cancer Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide, Australia
3Centre for Cancer Biology (CCB), Adelaide, Australia
4Department of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia
5Department of Haematology, SA Pathology, Adelaide, Australia
6Australasian Leukaemia and Lymphoma Group (ALLG), Melbourne, Australia
7South Australian Health and Medical Research Institute, University of Adelaide, Adelaide, Australia

Marcin M Machnicki1*, Iwona Solarska, PhD1,2*, Rafal Ploski, MD, PhD3*, Ilona Seferynska, MD, PhD4* and Tomasz Stoklosa, MD, PhD5

1Immunology, Medical University of Warsaw, Warsaw, Poland
2Institute of Hematology and Blood Transfusion, Warsaw, Poland
3Medical Genetics, Medical University of Warsaw, Warsaw, Poland
4Hematology, Institute of Hematology and Blood Transfusion, Warsaw, Poland
5Dept. of Immunology, Medical University of Warsaw, Warsaw, Poland

Renata Scopim-Ribeiro, M.Sc.1*, João Agostinho Machado-Neto, Ph.D.1*, Paula de Melo Campos, Ph.D.2*, Adriana da Silva Santos Duarte, Ph.D.2*, Priscila Santos Scheucher, Ph.D.3*, Amélia Góes, Ph.D.1*, Sara Teresinha Olalla Saad, M.D., Ph.D.2, Belinda Pinto Simoes, M.D., Ph.D.1, Eduardo Magalhães Rego, M.D., Ph.D.1 and Fabiola Traina, M.D., Ph.D.1

1Department of Internal Medicine, University of São Paulo at Ribeirão Preto Medical School, Ribeirão Preto, Brazil
2Hematology and Hemotherapy Center, Instituto Nacional de Ciência e Tecnologia do Sangue, University of Campinas, Campinas, Brazil
3Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Preto, Brazil

*signifies non-member of ASH