Olivier Hermine^1*, Ambroise Mar�ais, MD^2*, Thiago Maciel^3*, J Bagbor^2*, Darius Jagielski, VMD^4*, Nadine Holtermann, VMD^5*, Elena Martinez de Merlo, VMD^6*, Douglas H. Thamm, VMD^7*, Patrice Dubreuil, PhD^8* and Alain Moussy, MBA^8*

¹Department of Hematology, Necker Children's hospital, APHP, Paris, France
²Service d�h�matologie and Imagine Institute, Necker Hospital, Paris, France
³Service d�h�matologie and Imagine Institute, Necker Hospital, paris, France
⁴Bialobrzeska Veterinary Clinic, Warsaw, Poland
⁵Medizinische Kleintierklinik, Universit�t M�nchen, Munich, Germany
⁶Dept. of Animal Medicine and Surgery, HCVC, Complutense University of Madrid, Madrid, Spain
⁷The Animal Cancer Center, Colorado State University, Fort Collins, CO
⁸AB Science, Paris, France

Cody Paiva, BS^1*, Claire Godbersen^2*, Christopher George Danes, PhD,^3*, Stephen E Spurgeon, MD⁴, Allison Berger^3* and Alexey V Danilov, M.D. Ph.D.¹

¹OHSU Knight Cancer Institute, Portland, OR
²Dartmouth College, Lebanon, NH
³Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd., Cambridge, MA
⁴Center for Hematologic Malignancies, Oregon Health & Science University, Portland, OR

Michael Pfreundschuh, MD¹, Lorenz Thurner, MD^1*, Stefan Barth, Prof.Dr.^2*, Diana Pickert^3*, Natalie Fadle^1*, Maria Kemele^1*, Evi Regitz^1*, Frank Neumann, PhD^4*, Thomas Nachreiner, Dr.^3* and Klaus-Dieter Preuss, PhD^1*

¹Jos� Carreras Center for Immuno- and Gene Therapy and Internal Medicine I, Saarland University Medical School, Homburg/Saar, Germany
²Department of Experimental Medicine and Immunotherapy, Institute for Applied Medical Engineering, South African Research Chair in Cancer Biotechnology Institute of Infectious Disease and Molecular Medicine (IDM) Department of Integrative Biomedical Science Faculty of Health Sciences, Cape Town, South Africa
³Department of Experimental Medicine and Immunotherapy, Institute for Applied Medical Engineering, University Hospital RWTH Aachen, Aachen, Germany
⁴Jos� Carreras Center for Immuno- and Gene Therapy and Internal Medicine I, Saarland University Medical School, Homburg, Germany

Xiaolei Wei, Dr.^1*, Yun Mai, Dr.^1*, Ru Feng, MD² and B. Hilda Ye, PhD¹

¹Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY
²Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China

Juan J Gu, PhD^1*, Qunling Zhang, MD, PhD^1,2*, Cory Mavis, MSc^1*, Myron S. Czuczman, MD^1,3 and Francisco J. Hernandez-Ilizaliturri, MD¹

¹Departments of Medicine and Immunology, Roswell Park Cancer Institute, Buffalo, NY
²Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China
³Celgene Corporation, Summit, NJ

Patrick P. Ng, Daniel K. Lu^*, Juthamas Sukbuntherng^*, Jutta K. Neuenburg, Danelle F. James^* and Betty Y. Chang, PhD

Pharmacyclics LLC, an AbbVie Company, Sunnyvale, CA

Raphael Koch, MD^1* and Bjoern Chapuy, MD, PhD²

¹Hematology & Oncology, University Medical Center Goettingen, Goettingen, Germany
²Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

Joseph M. Gozgit^*, Youngchul Song^*, Scott Wardwell^*, Sara Nadworny^*, Yaoyu Ning^* and Victor M. Rivera

ARIAD Pharmaceuticals, Inc., Cambridge, MA

Amanda L Christie, B.S.^1*, Alexandra N. Christodoulou, M.S.^1*, Tiffany DeSouza, B.S.^1*, Mark A. Murakami, MD, MA¹, Loretta S. Li, MD², Nadja Kopp, M.S.^2*, Raphael Koch, MD^2*, Abner Louissaint Jr., MD, PhD³, Samuel Y. Ng, MD, PhD², Caron A. Jacobson, MD³, Brent Shoji, MD^4*, Matthew S. Davids, MD³, Oreofe O. Odejide, MD³, Ann S. LaCasce, MD³, David C. Fisher, MD², Arnold S. Freedman, MD², Eric D. Jacobsen, MD², Monica Bertagnolli, MD^4*, Geraldine S Pinkus, MD^5*, David M. Dorfman, MD, PhD⁶, Elizabeth A. Morgan, MD⁶, Jon C Aster, MD PhD⁵, Margaret A. Shipp, MD³ and David M. Weinstock²

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³Dana-Farber Cancer Institute, Boston, MA
⁴Department of Surgery, Brigham and Women's Hospital, Boston, MA
⁵Pathology, Brigham and Women's Hospital, Boston, MA
⁶Department of Pathology, Brigham and Women's Hospital, Boston, MA

Paul Peng, PhD¹, Joshua Brody, MD² and Linda Hammerich, PhD^1*

¹Icahn School of Medicine at Mount Sinai, New York, NY
²Ichan School of Medicine at Mount Sinai, New York, NY

Wei Liu, MD^1*, Archie Tamayo, MS^2*, Juan Chen, Ph.D^2*, Shimin Hu, PhD, MD^3*, Richard J. Ford Jr., MD, PhD⁴ and Lan Pham, PhD⁵

¹Department of Pathology, Soochow University, Suzhou, Jiangsu, China
²Department of Hematopathology, UT MD Anderson Cancer Center, Houston, TX
³University of Texas MD Anderson Cancer Center PTH Program, Houston, TX
⁴Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁵Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX

Guang Yang, PhD¹, Xia Liu, MD^1*, Jie Chen, PhD^1*, Lian Xu^1*, Nicholas Tsakmaklis^1*, Jiaji Chen^1*, Christopher J Patterson, MFA^1*, Jorge J Castillo, MD¹, Philip Cohen^2*, Li Tan, PhD^3*, Sara Buhrlage, PhD^3*, Nathanael Gray, PhD^3* and Steven P Treon, MD, PhD¹

¹Bing Center for WM, Dana Farber Cancer Institute, Boston, MA
²2MRC Protein Phosphorylation and Ubiquitylation Unit, College of Life Sciences, University of Dundee, Dundee, United Kingdom
³Dept of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA

Chiara Tarantelli^1*, Eugenio Gaudio^1*, Ivo Kwee^1*, Luciano Cascione^1*, Elena Bernasconi^1*, Petra Hillmann^2*, Anastasios Stathis, MD^3*, Georg Stussi, MD⁴, Doriano Fabbro^2*, Andreas Wicki^5*, Emanuele Zucca⁴, Vladimir Cmiljanovic^2* and Francesco Bertoni¹

¹Lymphoma and Genomics Research Program, IOR Institute of Oncology Research, Bellinzona, Switzerland
²PIQUR Therapeutics AG, Basel, Switzerland
³Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
⁴IOSI Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
⁵University of Basel, Basel, Switzerland

Qunling Zhang, MD, PhD^1,2*, Juan J Gu, PhD^1*, Ye Guo, MD^2*, Jacob Klos^1*, Cory Mavis, MSc^1*, Myron S. Czuczman, MD^1,3 and Francisco J. Hernandez-Ilizaliturri, MD¹

¹Departments of Medicine and Immunology, Roswell Park Cancer Institute, Buffalo, NY
²Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China
³Celgene Corporation, Summit, NJ

Hsiling Chiu^1*, Patrick Hagner, PhD^1*, Michael Pourdehnad, MD^2*, Thomas Daniel^3*, Rajesh Chopra¹, Anke Klippel¹, Christian Klein, PhD⁴, Anjan Thakurta^1* and Anita K. Gandhi, PhD^1*

¹Celgene Corporation, Summit, NJ
²Celgene Corporation, San Francisco, CA
³Celgene Corporation, San Diego, CA
⁴Roche Pharmaceutical Research and Early Development Roche Innovation Center, Zurich, Switzerland

Juan J Gu, PhD^1*, Qunling Zhang, MD, PhD^1,2*, Cory Mavis, MSc^1*, Myron S. Czuczman, MD^1,3 and Francisco J. Hernandez-Ilizaliturri, MD¹

¹Departments of Medicine and Immunology, Roswell Park Cancer Institute, Buffalo, NY
²Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China
³Celgene Corporation, Summit, NJ

Niranjan S. Rao, PhD^1*, Sanjeeva Reddy, PhD^1*, Gupta Sandeep, PhD^1*, Nitin K Damle, PhD^2*, Venkatesan M Aranapakam, PhD^3*, Scott Thompson, PhD^1*, Roger Smith, PhD^1*, Terry Plasse, MD^4*, Penelope Bristow, MS^1*, Anthony Tolcher, MD^5*, Kyriakos P Papadopoulos, MD⁵, Amita Patnaik, MD^5* and Drew W Rasco, MD^5*

¹Asana BioSciences, LLC, Bridgewater, NJ
²Preclinical R&D, Sun Pharma Advanced Research Co. Ltd.,, Mumbai 400093, India, Mumbai, India
³Axcellerate Pharma LLC, , NJ 08854, Piscataway, NJ
⁴Plasse Pharma, New York, NY
⁵START, San Antonio, TX

D�borah Revaud, PhD^1*, Ana Bejanariu, PhD^2*, Lamya Loussaief^1*, Emeline Sarry^2*, Abdel Zemmar^2*, Guillaume Deplaine, PhD^1*, T�reza Coman, MD^3,4,5,6*, Julien Rossignol, MD^3,4,5,6*, Olivier Hermine^3,4,5,7* and Cecile Bauche, PhD^2*

¹THERAVECTYS, Villejuif, France
²THERAVECTYS, VILLEJUIF, France
³Department of Hematology, Necker Children's hospital, APHP, Paris, France
⁴Imagine Institute, Sorbonne Paris Cit�, Paris Descartes University, Paris, France
⁵Centre de r�f�rence des d�ficits immunitaires h�r�ditaires (CEREDIH), Necker Children's hospital, APHP, Paris, France
⁶Imagine Institute, INSERM UMR 1163, CNRS ERL 8654, Paris, France
⁷Institut Imagine, INSERM 1163/CNRS ERL 8254, Paris, France

Madeleine Duvic, MD¹, Xiang Zhang^2*, Xiao Ni, MD, PhD¹, Timothy Langridge^3*, Rohinton Tarapore, Ph.D.^4* and Josh Allen, PhD^5*

¹Dept. of Dermatology, M.D. Anderson Cancer Center, Houston, TX
²Department of Dermatology, Univ of Texas MD Anderson Cancer Ctr, Houston, TX
³Dermatology, Univ of Texas MD Anderson Cancer Center, Houston, TX
⁴Oncoceutics, Inc, Hummelstown, PA
⁵Oncoceutics, Hummelstown, PA