-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

612. Acute Lymphoblastic Leukemia: Clinical Studies: Poster III

Acute Lymphoblastic Leukemia: Clinical Studies Program: Oral and Poster Abstracts
Type: Poster
Monday, December 7, 2015: 6:00 PM-8:00 PM
Hall A, Level 2 (Orange County Convention Center)

Zheng Ge, MD, PhD1, Xing Guo, MD1*, Jianyong Li, MD, PhD1, Melanie Hartman2*, Yuka Imamura Kawasawa3*, Sinisa Dovat, MD, PhD2 and Chunhua Song, PhD2

1Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
2Pennsylvania State University College of Medicine, Hershey, PA
3Penn State Hershey Genome Sciences Facility, Pennsylvania State University College of Medicine, Hershey, PA

Christian A. Fernandez, PhD1, Colton Smith, PhD1*, Wenjian Yang, PhD1*, Chengcheng Liu, B.S1*, Laura B. Ramsey, PhD1, Seth E. Karol, MD2, Ching-Hon Pui, MD2, William E. Evans, PharmD1, Sima Jeha, MD2 and Mary V. Relling, PharmD1

1Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN
2Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

Bijal D. Shah, MD1, Uma Borate, MD2, Vamsi K Kota, MD3, Ling Zhang, MD4, Deniz Peker, MD5*, Amanda Redden Hathaway, MD6 and Julio C Chavez, MD7

1Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL
2Univ. of Alabama at Birmingham, Birmingham, AL
3Winship Cancer Institute of Emory University, Atlanta, GA
4Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
5Pathology, University of Alabama-Birmingham, Birmingham, AL
6University of Alabama at Birmingham, Birmingham, AL
7Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL

Zhengshan Chen, MD PhD1*, Huimin Geng, PhD2*, Clifford A. Lowell, MD, PhD1*, Arthur Weiss, MD-PhD3*, Stephen P. Hunger4, Ari Melnick, MD5 and Markus Muschen, MD, PhD1

1Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
2Laboratory Medicine, University of California, San Francisco, San Francisco, CA
3University of California San Francisco, San Francisco, CA
4Children’s Hospital of Philadelphia and the Center for Childhood Cancer Research, Philadelphia, PA
5Weill Cornell Medical College, New York, NY

Sita D. Bhella, MD1, Eshetu G Atenafu, M.Sc., P.Stat.2*, Joseph Brandwein, MD, FRCPC3*, Vikas Gupta, MD, FRCP, FRCPath4, Johann Hitzler, MD, FRCP (C), FAAP5, Dina Khalaf, BSc, MSc, MD6, Andrzej Lutynski, MD7, Aaron D. Schimmer, MD, PhD4, Andre C Schuh, MD, FRCPC7, Amr Rostom, MD8*, Anna Rydlewski, MD9*, Karen W.L. Yee, MD4 and Mark D. Minden, MD, PhD4

1Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada
2Biostatistics Department, Princess Margaret Hospital, Toronto, ON, Canada
3University of Alberta, Edmonton, AB, Canada
4Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
5Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
6Princess Margaret Cancer Center, University of Toronto, TORONTO, ON, Canada
7Princess Margaret Cancer Centre, University Health Network, Leukemia Program, Division of Medical Oncology and Hematology, Toronto, ON, Canada
8University of Toronto, Princess Margaret Cancer Center, Leukemia Program, Toronto, Canada
9Leukemia Program, Princess Margaret Cancer Center, University of Toronto, Toronto, Canada

Punit L Jain, MD1*, Koji Sasaki, MD2, Hagop Kantarjian, MD3, Farhad Ravandi, MD4, Jorge E. Cortes, MD5, Guillermo Garcia-Manero, MD5, Prithviraj Bose, MD6*, Naval Daver, MD7, Tapan Kadia, MD5, Srdan Verstovsek, MD6, Marina Konopleva, MD, PhD6, Nitin Jain, MD6, Guillermo Bravo Montalban, MD8*, Sherry Pierce, BSN, BA6* and Elias Jabbour6

1Department of Leukemia, M D Anderson Cancer Center, Houston, TX
2Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
6Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, Houston, TX
8M D Anderson Cancer Center, University of Texas, Houston

Marta Sanchez-Martin, PhD1*, Alberto Ambesi-Impiombato, MD PhD1*, Luyao Xu1*, Yue Qin1*, Daniel Herranz, PhD1*, Mukesh Bansal, PhD2*, Tiziana Girardi3*, Kim De Keersmaecker4,5, Andrea Califano, PhD6* and Adolfo A. Ferrando, MD, PhD1,7,8

1Institute for Cancer Genetics, Columbia University, New York, NY
2Department of Systems Biology, Columbia University, New York, NY
3Laboratory for Disease Mechanisms in Cancer, O&N IV Herestraat, Leuven, Belgium
4Center for the Biology of Disease, VIB, Leuven, Belgium
5Department of Oncology, KU Leuven, Leuven, Belgium
6Department of Biomedical Informatics and Joint Centers for Systems Biology, Columbia University, New York, NY
7Department of Pediatrics, Columbia University, New York, NY
8Department of Pathology, Columbia University, New York, NY

Koji Sasaki, MD1, Elias Jabbour2, Deborah A Thomas, MD2, Maria R. Khouri3*, Musa Yilmaz, MD4*, Guillermo Garcia-Manero, MD2, Farhad Ravandi, MD2, Gautam Borthakur, MD2, Rebecca Garris2*, Evguenia Gachimova, BSN, RN2*, Jad Chahoud, MD5, Courtney DiNardo, MD2, Naveen Pemmaraju, MD2, Jorge E. Cortes2, Hagop M. Kantarjian, MD2 and Susan O'Brien, MD2

1Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Stem Cell Transplantation & Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Hematology & Oncology, Baylor College of Medicine, Houston, TX
5University of Texas Hosuton Health Science Center, Houston, TX

Koji Sasaki, MD1, Hagop M. Kantarjian, MD2, Susan O'Brien, MD2, Deborah A Thomas, MD2, Farhad Ravandi, MD2, Guillermo Garcia-Manero, MD2, Tapan Kadia, MD3, Nitin Jain, MD2, Marina Konopleva, MD, PhD4, Zeev Estrov, M.D.2, Koichi Takahashi, MD2, Maria R. Khouri5*, Jovitta Jacob, RN2*, Rebecca Garris2*, Jorge E. Cortes2 and Elias Jabbour2

1Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
4Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Stem Cell Transplantation & Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX

Musa Yilmaz, MD1*, Hagop M. Kantarjian, MD2, Jorge Cortes3, Guillermo Garcia-Manero, MD2, Jad Chahoud, MD4*, Farhad Ravandi, MD3, Koji Sasaki, MD2, Marina Konopleva, MD, PhD2, Koichi Takahashi, MD2, William G. Wierda4, Nitin Jain, MD2, Srdan Verstovsek, MD, PhD2, Zeev Estrov, MD4, Prithviraj Bose, MD4*, Sherry Pierce, BSN, BA2* and Elias Jabbour2

1Department of Hematology & Oncology, Baylor College of Medicine, Houston, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston

Andre Baruchel, MD1, Yves Bertrand, MD, PhD2*, Xavier Thomas, MD, PhD3, Nicolas Blin, MD4*, Emmanuelle Tavernier, MD5*, Stephane Ducassou, MD6*, Norbert Vey7, Virginie Gandemer, MD, PhD8, Victoria Cacheux, MD9*, Francoise Mazingue, MD10, Emmanuel Raffoux, MD, PhD11*, Genevieve PLAT12*, Jose Fernandes, MD13*, Poiree Maryline, MD14*, Luc Fornecker, MD15*, Jean-Louis Stephan, MD16*, Mathilde Hunault, MD, PhD17*, Anne Auvrignon, MD18*, Thibault Leguay, MD19*, Dominique Plantaz, MD, PhD20*, Stephane Lepretre, MD21*, Alina Ferster22, Isabelle Pellier, MD23*, Emmanuel Plouvier, MD24*, Claudine Schmitt, MD25*, Cecile Bonin, Pharm D26* and Iman El Hariry, MD, PhD26*

1Pediatric Hematology and Immunology Department, Robert Debré Hospital - APHP and University Paris Diderot, Paris, France
2Pediatric Hematology and Oncology Unit, IHOP, Lyon, France
3Hematology Department, Hopital Edouard Herriot, Lyon, France
4Department of Hematology, Nantes University Hospital, Nantes, France
5108 bis avenue Albert Raimond Hematology, Institut de Cancérologie de la Loire, Saint Priez en jarez, 42271, France
6Pediatric Hematology, CHU de Bordeaux,Hopital des Enfants-Hôpital Pellegrin, Bordeaux, France
7Hematology, Institut Paoli-Calmettes, Marseille, France
8Pediatric Hematology, Centre Hospitalier Universitaire de Rennes, Rennes, France
9Hematology Clermont Ferrand,, CHU Clermont Ferrand, Clermont Ferrand, France
10hematology, CHRU Lille, Lille, France
11Hematology Department, Saint Louis Hospital, Paris, France
12Hemato-pediatric, Children Hospital, Toulouse, France
13Centre Hospitalier Valenciennes Hematology, Valenciennes, France
14CHU Lenval Pediatric Hematology, Nice, France
15Oncology and Hematology, Hopital de Hautepierre, Strasbourg, France
16Pediatric Hematology, Institut de Cancérologie de la Loire, Saint Priez en jarez, 42271, France
17Hematology Department, CHU, Angers, France
18Pediatric Hematology, AP-HP,GH-HUEP Trousseau Hospital, PARIS, France
19Department of Hematology, CHU, Bordeaux, Bordeaux,, France
20Pediatric Hematology, CHU Grenoble site Nord, Grenoble, France
21Hematology, CLCC H Becquerel, Rouen, France
22HUDERF, Brussels, Belgium
23CHU Angers, Angers Cedex, France
24pediatric hematology, CHRU Besançon, Besançon, France
25Hôpital Brabois Enfants – CHU Nancy, Vandoeuvre, France
26ERYTECH Pharma, Lyon, France

Arata Watanabe1, Toshinori Hori2*, Yasuto Shimomura2*, Chihaya Imai, MD, PhD3, Atsushi Ogawa4*, Motoaki Chin5*, Hiroyuki Shichino6*, Yasuo Horikoshi7*, Keiko Nomura8*, Yutaka Saikawa9, Shouhei Yokota10*, Akiko Inoue11*, Takashi Taga, MD, PhD12*, Masahiko Okada13*, Jun-ichi Ueyama14*, Asayuki Iwai15*, Michihiro Yano16*, Yasuhiro Okamoto17, Masahito Tsurusawa18 and Atsushi Kikuta19*

1Nakadoori General Hospital, Akita, Japan
2Aichi Medical University, Nagakute, Japan
3Department of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
4Niigata Cancer Hospital, Niigata, Japan
5Nihon University Itabashi Hospital, Tokyo, Japan
6International Medical Research Center of Japan, Tokyo, Japan
7Shizuoka Children's Hospital, Shizuoka, Japan
8Faculty of Medicine, University of Toyama, Toyama, Japan
9Kanazawa Medical Univ., Kahokugun, Japan
10Kyoto Prefectural university of Medicine, Kyoto, Japan
11Osaka Medical College, Osaka, Japan
12Department of Pediatrics, Shiga University of Medical Science, Otsu, Japan
13Nagasaki University School of Medicine, Nagasaki, Japan
14Tottori University Faculty of Medicine, Yonago, Japan
15Shikoku Medical Center for Children and Adults, Zentsuji, Japan
16AKITA University Hospital, Akita, Japan
17Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
18Ama city hospital, Aichi, Japan
19Fukushima Medical University School of Medicine, Fukushima, Japan

Leidy L Isenalumhe, MD1,2, Ashley S. Margol, MD3*, Stan Louie, Pharm.D., Ph.D., FASHP4*, Michael Neely, MD, MSc, FCP5*, Richard Sposto, PhD3*, Jemily Malvar, MS6* and David Robert Freyer, DO, MS3*

1H Lee Moffitt Cancer Center & Research Institute, Tampa, FL
2University of South Florida, Tampa, FL
3Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, Los Angeles, CA
4University of Southern California, School of Pharmacy, Los Angeles, CA
5Department of Infectious Disease, Children's Hospital of Los Angeles, Keck School of Medicine, Los Angeles, CA
6Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA

Der-Cherng Liang, MD1, Hsiu-Ju Yen, MD2,3*, Wan-Hui Chang, MS4*, Hsi-Che Liu, MD5, Ting-Chi Yeh, MD5*, Giun-Yi Hung, MD2*, Kang-Hsi Wu, MD6*, Ching-Tien Peng, MD7*, Yu-Hsiang Chang, MD, PhD8*, Te-Kao Chang, MD9*, Chih-Cheng Hsiao, MD10*, Jiunn-Ming Sheen, MD10*, Yu-Hua Chao, MD11*, Tai-Tsung Chang, MD12*, Shyh-Shin Chiou, MD12*, Pei-Chin Lin, MD12*, Shih-Chung Wang, MD13*, Ming-Tsan Lin, MD13*, Wan-Ling Ho, MD, PhD14* and Yu-Chieh Chen, MD10*

1Mackay Memorial Hospital, Taipei, Taiwan
2Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan
3National Taiwan Normal University, Taipei, Taiwan
4Childhood Cancer Foundation, Taipei, Taiwan
5Mackay Memorial Hospital and Mackay Medical College, Taipei, Taiwan
6China Medical University Hospital, Taichung, Taiwan
7Children's Hospital of China Medical University, Taichung, Taiwan
8Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
9Taichung Veterans General Hospital, Taichung, Taiwan
10Chang Gung Children's Hospital–Kaohsiung, Kaohsiung, Taiwan
11Chung Shan Medical University Hospital, Taichung, Taiwan
12Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
13Changhua Christian Hospital, Changhua, Taiwan
14Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan

Lenka Hovorkova1,2*, Marketa Zaliova1,2, Nicola C Venn3*, Walter Muskovic3*, Jodie E Giles3*, Jana Linhartova4*, Katerina Machova Polakova4*, Peter J Shaw5, Rosemary Sutton3,6*, Jan Stary2, Jan Trka1,2 and Jan Zuna1,2

1CLIP, Childhood Leukaemia Investigation Prague, Prague, Czech Republic
2Department of Paediatric Haematology and Oncology, Charles University Prague, 2nd Faculty of Medicine and UH Motol, Prague, Czech Republic
3Children’s Cancer Institute Australia, Sydney, Australia
4Institute of Hematology and Blood Transfusion, Prague, Czech Republic
5Bone Marrow Transplant Services, Sydney Children’s Hospital Network, Westmead, Sydney, Australia
6School of Women's and Children's Health, University of New South Wales, Sydney, Australia

Feras Alfraih, MD1, Abdul Mannnan2*, Dennis Dong Hwan Kim, MD, PhD3, Ghuzayel Aldawsari, MD4*, Fahad Z. Alsharif, MBChB, MD5, Hazza A Alzahrani, MD4*, Said Y Mohamed, MD4*, Walid Rasheed, M.D.4*, Amr Hanbali, MD6*, Syed Osman Ahmed, MRCP, FRCPath4, Marwan Shaheen, MD4*, Fahad Al Mohareb, MD7*, Mahmoud Aljurf, MD, MPH8 and Naeem A. Chaudhri, MD, FACP4

1Oncology Centre, King Faisal Hospital and Research Centre, Riyadh, Saudi Arabia
2king Faisal Hospital and Research Centre, Riyadh, Saudi Arabia
3DMOH, Princess Margaret Hospital, Toronto, ON, Canada
4King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
5Kfcc, KFSHRC, MBC #64, Riyadh, Saudi Arabia
6Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
7Oncology Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
8King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Ashley Koegel, MD1,2*, Venee N. Tubman, MD, MMSc2,3,4 and Inga Hofmann, MD5

1Boston Children's Hospital, Boston, MA
2Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA
3Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA
4Department of Pediatrics, Harvard Medical School, Boston, MA
5Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA

Tasha Lin, MD1, Hassan B Alkhateeb, MD2*, Aref Al-Kali, MD2, Michelle Ann Elliott, MB, BCh2, Naseema Gangat, MBBS2, William J Hogan, MBChB2, Grzegorz S. Nowakowski, MD2, Carrie A. Thompson, MD2, Thomas E. Witzig, MD2, Stephen M. Ansell, M.D., Ph.D.2*, Mark R Litzow, MD2 and Mrinal M Patnaik, MBBS2

1Department of Internal Medicine, Mayo Clinic, Rochester, MN
2Division of Hematology, Mayo Clinic, Rochester, MN

Kevin Y Urayama, PhD, MPH1,2*, Masatoshi Takagi, MD, PhD3, Takahisa Kawaguchi, PhD4*, Keitaro Matsuo, MD, PhD5*, Yoichi Tanaka, PhD6*, Yuki Arakawa, MD7*, Daisuke Hasegawa, MD, PhD8*, Yuki Yuza, MD, PhD9*, Takashi Kaneko, MD, PhD9*, Yasushi Noguchi, MD, PhD10*, Yuichi Taneyama, MD, PhD11*, Setsuo Ota, MD12*, Takeshi Inukai, MD, PhD13*, Masakatsu Yanagimachi, MD, PhD14*, Dai Keino, MD, PhD15*, Kazutoshi Koike, MD16*, Daisuke Toyama, MD17*, Yozo Nakazawa, MD, PhD18*, Hidemitsu Kurosawa, MD19, Kozue Nakamura, MD20*, Koichi Moriwaki, MD21, Hiroaki Goto, MD, PhD22*, Yujin Sekinaka, MD23*, Daisuke Morita, MD24*, Motohiro Kato, MD, PhD25, Katsuyoshi Koh, MD, PhD7*, Yasushi Ishida, MD, PhD26*, Akira Ohara, MD, PhD27, Shuki Mizutani, MD, PhD3*, Fumihiko Matsuda, MD, PhD4* and Atsushi Manabe, MD, PhD8

1Department of Human Genetics and Disease Diversity, Tokyo Medical and Dental University, Tokyo, Japan
2St. Luke's International University, Tokyo, Japan
3Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Bunkyo-ku, Japan
4Center of Genomic Medicine, Kyoto University, Kyoto, Japan
5Division of Moleculer Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan
6School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan
7Department of Hematology and Oncology, Saitama Children's Medical Center, Saitama, Japan
8Department of Pediatrics, St. Luke's International Hospital, Tokyo, Japan
9Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan
10Japanese Red Cross Narita Hospital, Chiba, Japan
11Chiba Children's Hospital, Chiba, Japan
12Teikyo University Chiba Medical Center, Chiba, Japan
13Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan
14Graduate School of Medicine, Yokohama City University, Yokohama, Japan
15St. Marianna University School of Medicine, Kawasaki, Japan
16Ibaraki Children's Hospital, Mito, Japan
17School of Medicine, Showa University, Yokohama, Japan
18Shinshu University School of Medicine, Matsumoto, Japan
19Dokkyo Medical University, Tochigi, Japan
20Teikyo University Hospital, Tokyo, Japan
21Saitama Medical Center, Kawagoe, Saitama, Japan
22Division of Hemato-oncology/Regenerative Medicine, Kanagawa Children's Medical Center, Yokohama, Japan
23National Defense Medical College, Tokorozawa, Japan
24Nagano Children's Hospital, Nagano, Japan
25University of Tokyo, Tokyo, Japan
26Ehime Prefectural Central Hospital, Ehime, Japan
27Department of Pediatrics, Toho University School of Medicine, Tokyo, Japan

Punit Jain, DM1*, Prashant Deshpande, MD2*, Anu Korula, MD, DM2*, Nisham P N, DM2*, Ansu Abu Alex Sr., MSc2*, Fouzia NA, DM2*, Kavitha Lakshmi, MSc2*, Aby Abraham, MD, DM2*, Poonkuzhali Balasubramanian, M.Sc., Ph.D2, Alok Srivastava, MD2, Biju George, DM2* and Vikram Mathews, DM2

1Department of Leukemia, M D Anderson Cancer Center, Houston, TX
2Department of Haematology, Christian Medical College, Vellore, India

Mohamed NZ Massoud, MD1*, Hoda M Hassab, MD2*, Aida M M Ali, MD3* and Doha N Mohamed, MD1*

1Department of Pediatrics, Faculty of Medicine, Alexandria University, Alexandria, Egypt
2Clinical Research Center, Faculty of Medicine, Alexandria University, Alexandria, Egypt
3Department of Communitiy Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt

Yves Bertrand, MD, PhD1*, Andre Baruchel, MD2, Xavier Thomas, MD, PhD3, Nicolas Blin, MD4*, Emmanuelle Tavernier, MD5*, Stephane Ducassou, MD6*, Norbert Vey7, Virginie Gandemer, MD, PhD8, Victoria Cacheux, MD9*, Francoise Mazingue, MD10, Emmanuel Raffoux11*, Genevieve Plat, MD12*, Jose Fernandes, MD13*, Maryline Poiree, MD14*, Luc Fornecker, MD15*, Jean-Louis Stephan, MD16*, Mathilde Hunault, MD, PhD17*, Anne Auvrignon, MD18*, Thibault Leguay, MD19*, Dominique Plantaz, MD, PhD20*, Stephane Lepretre, MD21*, Alina Ferster, MD, PhD22, Isabelle Pellier, MD23*, Emmanuel Plouvier, MD24*, Claudine Schmitt25*, Cecile Bonin, Pharm D26*, Yann Godfrin, PhD26 and Iman El Hariry, MD, PhD26*

1Pediatric hematology, CHU Lyon, Lyon, France
2Pediatric Hematology and Immunology Department, Robert Debré Hospital - APHP and University Paris Diderot, Paris, France
3Hematology Department, Hopital Edouard Herriot, Lyon, France
4Department of Hematology, Nantes University Hospital, Nantes, France
5hematology, Institut de cancerologie de la Loire, Saint Priez en jarez, 42271, France
6Pediatric Hematology, CHU de Bordeaux,Hopital des Enfants-Hôpital Pellegrin, Bordeaux, France
7Hematology, Institut Paoli-Calmettes, Marseille, France
8Pediatric Hematology, Centre Hospitalier Universitaire de Rennes, Rennes, France
9Hematology Clermont Ferrand,, CHU Clermont Ferrand, Clermont Ferrand, France
10hematology, CHRU Lille, Lille, France
11Hematology Department, Saint Louis Hospital, Paris, France
12pediatric hematology, CHU Toulouse, Toulouse, France
13Centre Hospitalier Valenciennes Hematology, Valenciennes, France
14CHU Lenval Pediatric Hematology, Nice, France
15Oncology and Hematology, Hopital de Hautepierre, Strasbourg, France
16Hopital Nord - CHU Saint Etienne, Saint Priez en jarez, 42271, France
17Hematology Department, CHU, Angers, France
18Pediatric Hematology, AP-HP,GH-HUEP Trousseau Hospital, PARIS, France
19Department of Hematology, CHU, Bordeaux, Bordeaux,, France
20Pediatric Hematology, CHU Grenoble site Nord, Grenoble, France
21Hematology, CLCC H Becquerel, Rouen, France
22Dept. of Hémato-oncologie pédiatrique, Children's University Hospital Reine Fabiola, Brussels, Belgium
23CHU Angers, Angers Cedex, France
24pediatric hematology, CHRU Besançon, Besançon, France
25Pediatric Hematology, CHU de nancy, Nancy, France
26ERYTECH Pharma, Lyon, France

Judith M. Boer, PhD1, Aurélie Boeree, BSc1*, João R.M. Marchante, MSc1*, Berna Beverloo, PhD2,3*, Gabriele Escherich, MD4*, Hester A. de Groot-Kruseman, PhD3*, Rob Pieters, MD, PhD1,3,5 and Monique L. Den Boer, PhD1

1Department of Pediatric Oncology/Hematology, Erasmus MC - Sophia Children's Hospital, Rotterdam, Netherlands
2Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, Netherlands
3Dutch Childhood Oncology Group (DCOG), The Hague, Netherlands
4University Medical Center Hamburg Eppendorf, German Cooperative Study Group for Childhood Acute Lymphoblastic Leukemia (COALL), Eppendorf, Germany
5Princess Máxima Centre for Pediatric Oncology, Utrecht, Netherlands

*signifies non-member of ASH