Jan Styczynski¹, Beata Kurylo-Rafinska^1*, Malgorzata Kubicka^1*, Beata Kolodziej^1*, Monika Pogorzala^1*, Krzysztof Czyzewski^1*, Robert Debski^1*, Magdalena Wisniewska^1*, Mariusz Wysocki^1*, Michal Matysiak, Prof., MD PhD^2*, Iwona Malinowska^3*, Walentyna Balwierz, Prof MD PhD^4*, Edyta Juraszewska^5*, Jacek Wachowiak^6*, Benigna Konatkowska^6*, Mariola Woszczyk, MD PhD^7*, Igor Olejnik, MD^8*, Maryna Krawczuk-Rybak, Prof MD PhD^9*, Marta Kuzmicz^10*, Jerzy Kowalczyk, Prof MD PhD^11*, Maria Jolanta Stefaniak, MD, PhD^12*, Wanda Badowska^13*, Tomasz Szczepanski, Prof MD, PhD¹⁴, Renata Tomaszewska^15*, Elzbieta Adamkiewicz-Drozynska^16*, Lucyna Maciejka-Kemblowska^16*, Grazyna Sobol^17*, Agnieszka Mizia-Malarz^17* and Joanna Szczepanek^18*

¹Department of Pediatric Hematology and Oncology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland
²Department of Pediatrics, Hematology and Oncology, Medical University of Warsaw, Warsaw, Poland
³Department of Pediatric Hematology and Oncology, Medical University Warsaw, Warsaw, Poland
⁴Department of Pediatric Oncology and Hematology, Jagiellonian University Medical College,, Krakow, Poland
⁵Department of Pediatric Oncology and Hematology, Jagiellonian University Medical College, Krakow, Krakow, Poland
⁶Department of Pediatric Hematology, Oncology and Transplantology, University of Medical Sciences, Poznan, Poznan, Poland
⁷Department of Pediatric Hematology and Oncology, Pediatric Center, Chorzow, Poland
⁸Department of Pediatric Hematology and Oncology, Pediatric Center Chorzow, Chorzow, Poland
⁹Department of Pediatric Hematology and Oncology, Medical University, Bialystok, Poland
¹⁰Department of Pediatric Hematology and Oncology, Medical University Bialystok, Bialystok, Poland
¹¹Department of Pediatric Hematology, Oncology and Transplantology, Medical University, Lublin, Poland
¹²Department of Pediatric Hematology, Oncology and Transplantology, Medical University Lublin, Lublin, Poland
¹³Department of Pediatric Hematology and Oncology, Children Hospital Olsztyn, Olsztyn, Poland
¹⁴Department of Pediatric Hematology and Oncology, Medical University of Silesia, Zabrze, Poland
¹⁵Department of Pediatric Hematology and Oncology, Medical University of Silesia, Zabrze, Zabrze, Poland
¹⁶Department of Pediatric Hematology and Oncology, Medical University Gdansk, Gdansk, Poland
¹⁷Department of Pediatrics, Medical University of Silesia, Katowice, Katowice, Poland
¹⁸Centre for Modern Interdisciplinary Technologies, Department of Plant Physiology and Biotechnology, Nicolaus Copernicus University, Torun, Torun, Poland

Stacey Tannheimer, PhD^*, Jia Liu, Ph.D.^*, Rick Sorensen, BS^*, Anella Yahiaoui, BS^*, Sarah Meadows^*, Li Li, PhD, Peng Yue, PhD^*, Kathleen S Keegan, Ph.D.^*, Jamie Bates, Ph.D.^*, Daniel Tumas, PhD, DVM^* and Christophe Queva, PhD

Gilead Sciences, Foster City, CA

Luke Fostvedt^1*, A. Douglas Laird^1*, Jean-Claude Marshall^2*, Sherry Li^3* and Joseph P. Boni, PhD, BS^4*

¹Pfizer Inc, La Jolla, CA
²Pfizer Inc, Groton, CT
³Pfizer Inc, Shanghai, China
⁴Pfizer Inc, Collegeville, PA

Ida Franiak-Pietryga, Ph.D.^1*, Henryk Maciejewski, Ph.D.^2*, Barbara Ziemba, Ph.D.^3*, Dietmar Appelhans, Ph.D.^4*, Brigitte Voit, Professor^4*, Malgorzata Misiewicz, Ph.D.^5*, Tadeusz Robak, MD, Professor⁶, Jacek Trelinski, MD, Professor^7*, Maria Bryszewska, Professor^3* and Maciej Borowiec, Professor^1*

¹Department of Clinical and Laboratory Genetics, Medical University, Lodz, Poland
²Institute of Computer Engineering, Control and Robotics I-6, Wroclaw University of Technology, Wroclaw, Poland
³Department of General Biophysics, University of Lodz, Lodz, Poland
⁴Leibniz Institute of Polymer Research, Dresden, Germany
⁵Department of Hematology, Medical University, Lodz, Poland
⁶Department of Hematology, Medical University of Lodz and Copernicus Memorial Hospital, Lodz, Poland
⁷Department of Hematology, Medical UniversityUniversity, Lodz, Poland

Yoko Kado, BS^1,2*, Fumiaki Kitazawa, MS^1*, Masayuki Tsujimoto, PhD^3*, Shin-ichi Fuchida, MD, PhD^4*, Akira Okano, MD, PhD^4*, Mayumi Hatsuse, MD^4*, Satoshi Murakami, MD^4*, Kumi Ueda, BS^1*, Takatoshi Kokufu, BS^1*, Shoichi Ozawa^3*, Natsuko Ito^3*, Satoe Morishita^3*, Tetsuya Takada, BS^2*, Tetsuya Minegaki, PhD^3*, Kohshi Nishiguchi, PhD^3*, Eishi Ashihara, MD, PhD² and Chihiro Shimazaki, MD, PhD⁴

¹Department of Pharmacy, Japan Community Health care Organization Kyoto Kuramaguchi Medical Center, Kyoto, Japan
²Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan
³Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan
⁴Department of Hematology, Japan Community Health care Organization Kyoto Kuramaguchi Medical Center, Kyoto, Japan

Hideki Goto, MD, PhD^1,2*, Rachel Wilkie Grantham, PhD^1*, Motoaki Mizuuchi^3*, Tetsuji Yamaguchi^3*, Takanori Teshima, MD, PhD², John C. Reed, MD, PhD¹ and Shu-ichi Matsuzawa, PhD^1*

¹Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA
²Department of Hematology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
³JSR micro Inc., La Jolla, CA

Monica Mead, MD, BS^1*, Erika Von Euw, PhD, BS^2*, Dylan Conklin^2*, Ben Powell, PhD, BS^3*, Kanthinh Manivong, BS^2*, Eileen Do^4*, Dennis J. Slamon, MD, PhD^5* and Sarah Larson, MD⁶

¹UCLA Medical Center, Los Angeles, CA
²Division of Hematology and Oncology, University of California, Los Angeles, Los Angeles, CA
³Plexxikon, Berkley, CA
⁴NYP, Weill Cornell Medical Center, New York, NY
⁵Division of Hematology/Oncology, Department of Medicine, UCLA, Los Angeles, CA
⁶University of California, Los Angeles, CA

Luigi Scotto, PhD^1*, Xavier Jirau-Serrano, BS^1*, Kelly Zullo, MS^1*, Michael Mangone, PhD^1*, Jennifer E Amengual, MD¹, Changchun Deng, MD, PhD² and Owen A. O'Connor, MD, PhD¹

¹Center for Lymphoid Malignancies, Department of Medicine, Columbia University Medical Center, New York, NY
²Center for Lymphoid Malignancies, Columbia University Medical Center, New York, NY

Baohua Sun, MD, PhD¹, Warren Fiskus, Ph.D¹, Dyana T Saenz^1*, Stephanie Krieger^1*, Liang Zhang, MD, PhD², Simrit Parmar, MD³, Michael Wang, MD⁴ and Kapil N. Bhalla, MD⁵

¹Department of Leukemia, MD Anderson Cancer Center, Houston, TX
²Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Seongseok Yun, MD, PhD^1*, Nicole D. Vincelette^2*, Katherine L. B. Knorr, PhD³, Luciana L. Almada, PhD^4*, Paula A. Schneider^4*, Kevin L. Peterson, PhD^4*, Karen S. Flatten^4*, Allan D. Hess, PhD⁵, B. Douglas Smith, MD⁶, Judith E. Karp, MD⁷, Martin E. Fernandez-Zapico, MD⁴ and Scott H. Kaufmann, MD, PhD⁸

¹University of Arizona, Tucson, AZ
²Mayo Graduate School, Rochester, MN
³Mayo Medical and Graduate Schools, Rochester, MN
⁴Mayo Clinic, Rochester, MN
⁵Department of Oncology, Division of Hematological Malignancies, Sidney Kimmel Comprehensive Cancer Center at John Hopkins, Baltimore, MD
⁶Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
⁷Johns Hopkins University, Baltimore, MD
⁸Oncology Research, Mayo Clinic, Rochester, MN

Greg P. Coffey, PhD^1*, Jiajia Feng, MD^1*, Glenn Michelson, MD^1*, Janet Leads, PhD^1*, John T. Curnutte, MD, PhD², Anjali Pandey, PhD^1* and Pamela B. Conley, PhD²

¹Portola Pharmaceuticals Inc, South San Francisco, CA
²Portola Pharmaceuticals, Inc., South San Francisco, CA

Sarah Meadows^*, Sorensen Rick^*, Yahiaoui Anella^*, Jia Liu, PhD^*, Li Li, PhD, Peng Yue, PhD^*, Christophe Queva, PhD and Stacey Tannheimer, PhD^*

Gilead Sciences, Foster City, CA

Jennifer E Amengual, MD¹, Maximilian Lombardo^1*, Kelly M Zullo^1*, Paul M. Johannet, BA², Sathyen A Prabhu^1*, Gonzalez Yulissa^1*, Luigi Scotto, PhD^3*, Ying Wei^4*, Jimmy Duong^4* and Owen A. O'Connor, MD, PhD³

¹Center for Lymphoid Malignancies, Columbia University Medical Center, New York, NY
²Stanford University, Stanford, CA
³Center for Lymphoid Malignancies, Department of Medicine, Columbia University Medical Center, New York, NY
⁴Department of Biostatistics, Mailman School of Public Health, Columbia University Medical Center, New York, NY

Eugen Dhimolea, PhD^1*, Emily King^1*, Michal Sheffer, PhD^1*, Yiguo Hu, MD, PhD^1*, Pallavi P. Awate^1*, Subhashis Sarkar, PhD^1*, Geoffrey M. Matthews, PhD^1*, Megan Murnane^2*, Megan A. Bariteau, BSc^1*, Blake T. Aftab, PhD² and Constantine S Mitsiades, MD, PhD¹

¹Dept. of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²Dept. of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA

Sara Redaelli, PhD^1*, Monica Ceccon, PhD^2*, Alessandra Pirola, MSc^1*, Marco Peronaci, MSc^2*, Carlo Gambacorti-Passerini, MD^1,3 and Luca Mologni, PhD^2*

¹Dept. of Health Sciences, University of Milano-Bicocca, Monza, Italy
²Dept. of Health Sciences, University of Milano Bicocca, Monza, Italy
³Hematology and Clinical Research Unit, San Gerardo Hospital, Monza, Italy

Samantha N. Reiss, PharmD^1*, Larry W. Buie, PharmD, BCOP^1*, Nelly G. Adel, PharmD, BCOP, BCPS^1*, Debra A. Goldman, MS^2*, Sean Devlin, PhD^2* and Dan Douer, MD³

¹Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
³Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

Niels Franke, MD^1*, Gertjan J.L. Kaspers, MD, PhD¹, Yehuda G Assaraf, PhD^2*, Johan Van Meerloo, MSc^1*, Denise Niewerth, PhD^1*, Terzah M. Horton, MD, PhD³, Wee Joo Chng, MD, PhD^4,5, Chonglei Bi, B.S^4*, Rene X. Menezes, PhD^6*, Renée J. Musters, PhD^7*, Pino J. Poddighe, PhD^8*, Floortje Kessler^9*, Serge Smeets, PhD^10*, Bauke Ylstra, PhD^11*, Sonja Zweegman, MD, PhD¹², Gerrit Jansen, PhD^13* and Jacqueline Cloos, PhD^1,9*

¹Department of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, Netherlands
²Department of Biology, The Fred Wyszkowski Cancer Research Laboratory, Technion-Israel Institute of Technology, Haifa, Israel
³Pediatrics, Hematology/Oncology, Baylor College of Medicine, Houston, TX
⁴Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
⁵Department of Haematology-Oncology, National University Cancer Institute of Singapore, National University Health System, Singapore, Singapore
⁶Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, Netherlands
⁷Department of Physiology, VU University Medical Center, Amsterdam, Netherlands
⁸Department of Genetics, VU University Medical Center, Amsterdam, Netherlands
⁹Department of Hematology, VU University Medical Center, Amsterdam, Netherlands
¹⁰Novartis Pharma, Arnhem, Netherlands
¹¹Department of Pathology, VU University Medical Center, Amsterdam, Netherlands
¹²Department of Hematology, VUMC, Amsterdam, Netherlands
¹³Dept of Rheumatology, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands