Purushothama Nanjappa^1*, Subodh Kumar, PhD^1*, Srikanth Talluri, PhD^1,2*, Humza Ahmad^1*, Ahsun Bajwa^1*, Jialan Shi, MD, PhD², Gabriel Gonzalez, PhD^2*, Florence Magrangeas^3*, Stephane Minvielle^3*, Kenneth C Anderson¹, Herve Avet-Loiseau^3,4*, Masood Shammas, Ph.D.^1,2 and Nikhil C. Munshi, MD^5,6

¹The Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²VA Boston Healthcare System, west roxbury, MA
³Centre Hospitalier Universitaire de Nantes, Unité Mixte de Genomique du Cancer, Nantes, France
⁴IUCT-Oncopole, Toulouse, France
⁵VA Boston Healthcare System, West Roxbury, MA
⁶Jerome Lipper Multiple Myeloma Center, Dana Farber Cancer Institute, Boston, MA

Masood A Shammas, PhD^1,2, Subodh Kumar, PhD^1,2*, Purushothama Nanjappa^2*, Mehmet K Samur, Ph.D^3*, Srikanth Talluri, PhD^2,4*, Jianhong Lin, M.D, M.Sc^5*, Florence Magrangeas^6*, Stephane Minvielle^6*, Hervé Avet-Loiseau, MD^7* and Nikhil C. Munshi, MD^2,4

¹VA Boston Healthcare System, West Roxbury, MA
²The Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
³Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
⁴VA Boston Healthcare System, west roxbury, MA
⁵Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁶Centre de Recherche en Cancérologie Nantes-Angers UMR Inserm 892—CNRS 6299 and Institut de Recherche Thérapeutique de l’Université de Nantes (IRT-UN), Nantes, France
⁷Centre de Recherche en Cancérologie de Toulouse Institut National de la Santé, Toulouse, France

Antonella Padella^1*, Giorgia Simonetti, PhD^1*, Giulia Paciello^2*, Anna Ferrari, PhD^1*, Elisa Zago, PhD^3*, Carmen Baldazzi, PhD^1*, Viviana Guadagnuolo, PhD^1*, Cristina Papayannidis, MD, PhD⁴, Valentina Robustelli^5*, Enrica Imbrogno^5*, Nicoletta Testoni^1*, Gerardo Musuraca^6*, Simona Soverini⁷, Massimo Delledonne, PhD^3*, Ilaria Iacobucci, PhD^8*, Clelia Tiziana Storlazzi, PhD^9*, Elisa Ficarra, PhD^2* and Giovanni Martinelli⁸

¹University of Bologna, Bologna, Italy
²Dept. of Control and Computer Engineering DAUIN, Politecnico di Torino, Turin, Italy
³Personal Genomics, Verona, Italy
⁴Bologna University School of Medicine, Bologna, Italy
⁵DIMES, Department of Hematology and Medical Sciences “L. and A. Seràgnoli”, University of Bologna, Bologna, Italy
⁶Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori, Meldola (FC),, Meldola, Italy
⁷Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
⁸"Seràgnoli" Institute of Hematology, University of Bologna, Bologna, Italy
⁹Department of Biology, University of Bari, Bari, Italy

Maria Gkotzamanidou^1,2, Evangelos Terpos¹, Nikhil C. Munshi, MD³, Vassilis L. Souliotis^4* and Meletios A. Dimopoulos⁵

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
²Department of Medical Oncology, Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
³LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁴Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece
⁵National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Joe Chin-Sun Huang, MD^1*, Julia Sidorova, PhD^2*, Sylvia Chien^3*, Jin Dai^3*, Ben Logsdon, PhD^4*, Su-In Lee, PhD^5*, Raymond J Monnat, MD^6* and Pamela S. Becker, MD, PhD^3,7

¹Division of Gerontology and Geriatric Medicine, University of Washington, Seattle, WA
²Department of Pathology, University of Washington, Seattle, WA
³Division of Hematology and Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA
⁴Sage Bionetworks, Seattle, WA
⁵Computer Science and Engineering and Genome Sciences, University of Washington, Seattle, WA
⁶Genome Sciences and Pathology, University of Washington, Seattle, WA
⁷Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA