Víctor Jiménez-Yuste, Dr^1*, Johannes Oldenburg, MD, PhD², Savita Rangarajan, MBBS, FRCP, FRCPath³, Roser Peiró, PhD^4* and Elena Santagostino, MD, PhD^5*

¹Haematology Department, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Madrid, Spain
²Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany
³The Centre for Haemostasis and Thrombosis, St Thomas' Hospital, London, United Kingdom
⁴Scientific and Medical Affairs, Grifols, Sant Cugat del Vallès, Spain
⁵Centro Emofilia e Trombosi "Angelo Bianchi Bonomi", Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy

Kingsley Hampton^1*, Pratima Chowdary^2*, Scott Dunkley^3*, Silke Ehrenforth, MD, PhD⁴, Lotte Jacobsen^4*, Anne T. Neff, MD⁵, Elena Santagostino, MD, PhD⁶, Jameela Sathar^7*, Hideyuki Takedani^8*, Clifford M. Takemoto, MD⁹ and Claude Négrier^10*

¹Department of Cardiovascular Science, University of Sheffield, Sheffield, United Kingdom
²Royal Free Hospital, London, United Kingdom
³Institute of Haematology, Royal Prince Alfred Hospital, Sydney, Australia
⁴Novo Nordisk, Søborg, Denmark
⁵Vanderbilt University Medical Center, Nashville, TN
⁶Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy
⁷Department of Hematology, Hospital Ampang, Kuala Lumpur, Malaysia
⁸Department of Joint Surgery, Research Hospital, Institute of Medical Science, University of Tokyo, Tokyo, Japan
⁹Division of Pediatric Hematology, The Johns Hopkins University, Baltimore, MD
¹⁰Department of Haematology, Louis Pradel University Hospital, Bron, France

Panagiotis Anagnostis^1*, Sofia Vakalopoulou^1*, Dimitrios Christoulas^2*, Spyridon Karras^3*, Athanasios Papatheodorou^4*, Eirini Katodritou^5*, Panagiotis Kokkoris^4*, Vasilia Garipidou^1* and Evangelos Terpos⁶

¹Hemophilia Center of Northern Greece, 2nd Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, School of Medicine, Hippokration Hospital, Thessaloniki, Greece
²Department of Hematology, 251 General Air Force Hospital, Athens, Greece
³Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, School of Medicine, ‘‘Papageorgiou’’ General Hospital, Thessaloniki, Greece
⁴Department of Medical Research, 251 General Air Force Hospital, Athens, Greece
⁵Department of Hematology, Theagenio Cancer Hospital, Thessaloniki, Greece
⁶Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Peter H. Cygan, MD¹, Laura Carrel, Ph.D^2* and M. Elaine Eyster, MD¹

¹Department of Medicine, Division of Hematology/Oncology, Penn State Hershey Medical Center, Hershey, PA
²Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, PA

Maitri Kalra, MBBS¹, Ashish Aggarwal^2*, Vikas Kalra^1*, Laura Caragol^3*, Marwan Ghabril^1* and Naveen Manchanda, MBBS⁴

¹Indiana University, Indianapolis, IN
²Community Hospital, Indianapolis, IN
³University of Colorado, Denver, CO
⁴Simon Cancer Center, IU Hospital, Indianapolis, IN

Yesim G. Dargaud, MD, PhD¹, Yohann Jourdy^2*, Sandra Le Quellec^2*, Coen Hemker^3*, Theo Lindhout^4*, Elisabetta Castoldi^4* and Claude Negrier, MD⁵

¹Hopital Edouard Herriot Pav. E, Lyon, France
²Hopital Edouard Herriot, Lyon, France
³Synapse bv, Maastricht, Netherlands
⁴University of Maastricht, Maastricht, Netherlands
⁵Hôpital Edouard Herriot, University Claude Bernard, Lyon, France

Charles T Nakar, MD¹, Roberto Caputo, MD^2*, Francis W Price Jr., MD^3*, Maria Teresa Sartori, MD^4*, Andrea Leonardi^5*, Anna Lotti Suffredini^6*, Neelam Thukral^7*, Jacopo Secci^2*, Bennie H Jeng, MD^8* and Amy D Shapiro, MD⁹

¹Pediatric Hematology, Indiana Hemophilia & Thrombosis Center, Indianapolis, IN
²Pediatric Ophthalmology Unit, A. Meyer Children's Hospital, Florence, Italy
³Price Vision Group, Indianapolis, IN
⁴Department of Cardiologic, Thoracic and Vascular Sciences, University of Padova, Padova, Italy
⁵Department of Neuroscience, Ophthalmology Unit, University of Padova, Padova, Italy
⁶Clinical Development and Operations Group, Kedrion SpA, Lucca, Italy
⁷Indiana Hemophilia and Thrombosis Center, Indianapolis, IN
⁸Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, MD
⁹Indiana Hemophilia & Thrombosis Center, Indianapolis, IN

Beth Boulden Warren, MD, MS¹, Linda Jacobsen, BS^2*, Elizabeth Villalobos-Menuey, BS^2*, Thomas C. Abshire, MD³, Amy D Shapiro, MD⁴, Michael Recht, MD, PhD⁵, Deborah Brown, MD⁶, Cindy A. Leissinger, MD⁷, Christine L. Kempton, MD, MSc⁸, Heidi Lane, PT, DPT, PCS^9*, Diane J. Nugent, MD¹⁰ and Marilyn J. Manco-Johnson, MD¹¹

¹Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO
²University of Colorado Anschutz Medical Campus, Aurora, CO
³Blood Center of Wisconsin, Milwaukee, WI
⁴Indiana Hemophilia & Thrombosis Center, Indianapolis, IN
⁵Ohio State University, Columbus, OH
⁶Department of Pediatrics- Hematology Division, University of Texas, Houston, TX
⁷Tulane University School of Medicine, New Orleans, LA
⁸Department of Pediatrics, Emory University, Atlanta, GA
⁹University of Utah, Salt Lake City, UT
¹⁰Children's Hospital of Orange County, Orange, CA
¹¹Hemophilia and Thrombosis Center, Dept of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO

Pal André Holme, PhD, MD^1*, Robert Campbell Tait, MD^2*, Christophe Combescure, PhD^3*, Erik Berntorp, MD, PhD⁴, Annarita Tagliaferri^5*, Peter Staritz, MD^6*, Roger E.G. Schutgens, MD, PhD⁷, Robert Klamroth^8*, Natascha Marquardt^9*, Stephan Rauchensteiner^10* and Philippe De Moerloose, MD, PhD^11*

¹Department of Haematology, Oslo University Hospital, Oslo, Norway
²Royal Infirmary, Glasgow, United Kingdom, Glasgow, United Kingdom
³3University Hospital and Faculty of Medicine of Geneva, Geneva, Switzerland, Geneva, Switzerland
⁴Lund University, Malmö, Sweden, Malmö, Sweden
⁵5University Hospital of Parma, Parma, Italy, Parma, Italy
⁶Kurpfalz Hospital and Hemophilia Center, Heidelberg, Germany, Heidelberg, Germany
⁷Hematology and Van Creveldkliniek, University Medical Center, Utrecht, Netherlands
⁸Vivantes Clinic Friedrichshain, Berlin, Germany
⁹Institute for Experimental Haematology and Transfusion Medicine, University Clinic, Bonn, Germany, Bonn, Germany
¹⁰Bayer Healthcare, Berlin, Germany., Berlin, Germany
¹¹University Hospital and Faculty of Medicine of Geneva, Geneva, Switzerland, Geneva, Switzerland

Devi Gunasekera, MBBS^1*, Debargh Kumar Dutta, PhD^1*, Eddie A. James, Ph.D.^2*, Margaret V Ragni³ and Kathleen P. Pratt, Ph.D.¹

¹Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD
²Benaroya Research Institute, Seattle, WA
³University of Pittsburgh and Hemophilia Center of Western PA, Pittsburgh, PA

Kevin R. Viel, Ph.D.^1*, Marco Hofmann, MD, PhD^2*, Sabine Zollner^2*, Bernadette W. Luu^3*, Rajalingam Raja, PhD^4*, Jerry Sherman Powell, MD⁵, Eugene Maraskovsky, M.D., Ph.D.^6* and Tom E. Howard, MD, PhD^7,8,9*

¹Histonis, Inc., Atlanta, GA
²CSL Behring, Marburg, Germany
³Department of Pathology and Laboratory Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA
⁴Immunogenetics Center, University of California at San Francisco, San Francisco, CA
⁵CSL Behring, King of Prussia, PA
⁶CSL Behring, Melbourne, Australia
⁷Pathology and Laboratory Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA
⁸Department of Pathology and Laboratory Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
⁹Division of Hematology & Oncology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA

Margaret V Ragni^1,2, Giancarlo Castaman^3,4*, Joan Cox Gill^5,6, Peter Kouides^7,8*, Miranda Chapman^9*, Arthur Sytkowski^9*, Ortrun Obermann-Slupetzky^10*, Isabella Presch¹⁰, Sandor Fritsch^10* and Bruce M. Ewenstein⁹

¹Hemophilia Center of Western Pennsylvania, University of Pittsburgh, Pittsburgh, PA
²University of Pittsburgh and Hemophilia Center of Western Pennsylvania, Pittsburgh, PA
³San Bortolo Hospital, Vicenza, Italy
⁴Center for Bleeding Disorders, Careggi University Hospital, Florence, Italy
⁵Medical College of Wisconsin, Milwaukee, WI
⁶BloodCenter of Wisconsin and Medical College of Wisconsin, Milwaukee, WI
⁷University of Rochester School of Medicine, Rochester, NY
⁸Mary Gooley Hemophilia Center, Rochester, NY
⁹Baxalta US Inc., Cambridge, MA
¹⁰Baxalta Innovations GmbH, Vienna, Austria

Amy D Shapiro, MD¹, David J Perry², Ross I Baker, MD³, Elisa Tsao^4* and Baisong Mei^4*

¹Indiana Hemophilia & Thrombosis Center, Indianapolis, IN
²Addenbrooke’s Hospital, Cambridge, United Kingdom
³Western Australia Centre for Thrombosis and Haemostasis, Murdoch University, Perth, Australia
⁴Biogen, Cambridge, MA

Pedro Paz^1*, Jens Schroeder^2*, Prasad Mathew³, Marion Hardtke^2* and Fred Aswad^1*

¹Global Biologics Research, Lead Discovery, Bayer HealthCare, San Francisco, CA
²Global Clinical Development, Bayer Pharma AG, Berlin, Germany
³Bayer HealthCare Pharmaceuticals, Whippany, NJ

Margaret Carlisle Cupit, BS¹, Amulya NageswaraRao, MBBS^2*, Deepti M. Warad, M.B.B.S.^3,4, Shakila Khan, MD⁵ and Vilmarie Rodriguez, MD⁴

¹Mayo Medical School, Mayo Clinic, Rochester, MN
²Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN
³Division of Hematopathology, Special Coagulation Laboratory, Mayo Clinic, Rochester, MN
⁴Division of Pediatric Hematology and Oncology, Mayo Clinic, Rochester, MN
⁵Division of Pediatric Hematology-Oncology, Mayo Clinic, Rochester, MN

A. Kathleen Hesselton^1*, Michael Mosier^2*, Debra Hoppensteadt, PhD^1*, Walter Jeske, PhD^3* and Jawed Fareed, PhD¹

¹Department of Pathology, Loyola University Medical Center, Maywood, IL
²Department of Surgery, Loyola University Medical Center, Maywood, IL
³Department of Thoracic and Cardiovascular Surgery, Loyola University Medical Center, Maywood, IL

Claude Negrier, MD¹, Lynda Mae Lepatan, MD^2*, Faralzah Karim, MD^3*, Anne Lienhart, MD^1*, Denise Wolko^4*, Christine Voigt, PhD^4*, Iris C. Jacobs, MD⁴ and Elena Santagostino, MD, PhD⁵

¹Hôpital Edouard Herriot, University Claude Bernard, Lyon, France
²Perpetual Succour Hospital, Cebu City, Philippines
³National Blood Centre, Haemophilia Centre, Kuala Lumpur, Malaysia
⁴CRD, CSL Behring, King of Prussia, PA
⁵Centro Emofilia e Trombosi, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy

Brigitte Brand¹, Ralph A. Gruppo, MD², Tung T. Wynn³, Laimonas Griskevicius^4*, Maria Fernanda Lopez Fernandez^5*, Thomas Dvorak^6*, Lisa Patrone^7* and Brigitt E. Abbuehl⁶

¹Universitaetsspital Zuerich, Zeurich, Switzerland
²Cincinnati Children's Hospital Medical Center, Cincinnati, OH
³University of Florida, Gainesville, FL
⁴Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania
⁵5Complejo Hospitalario Universitario A Coruña, A Coruña, Spain
⁶Baxalta, Vienna, Austria
⁷Baxalta, Westlake Village, CA

Marilyn J. Manco-Johnson, MD¹, Alice D. Ma, MD², Robert Klamroth^3*, Werner Engl^4*, Lorena Griparic, PhD^5*, Jacqueline A Dyck-Jones, PhD^5* and Brigitt E. Abbuehl⁴

¹Mountain State Regional Hemophilia and Thrombosis Center, University of Colorado Anschutz Medical Campus, Aurora, CO
²Hemophilia Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC
³Vivantes Clinic Friedrichshain, Berlin, Germany
⁴Baxalta, Vienna, Austria
⁵Baxalta US Inc., Westlake Village, CA

Haowei (Linda) Sun, MD¹, Ming Yang, PhD^2*, Afrah S Sait, MD^3*, Annette Von Drygalski, MD, PharmD⁴ and Shannon Jackson^5,6

¹University of British Columbia, Vancouver, BC, Canada
²British Columbia Provincial Bleeding Disorders Program-Adult Division, Vancouver, BC, Canada
³Department of Medicine, University of British Columbia, Vancouver, BC, Canada
⁴Division of Hematology/Oncology, Department of Medicine, University of California San Diego, San Diego, CA
⁵Division of Hematology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
⁶St Paul’s Hospital, Vancouver, BC, Canada

Guy Young, MD¹, Miguel Escobar^2*, Steven Pipe, MD³ and David L. Cooper, MD, MBA⁴

¹Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA
²University of Texas Health Science Center and The Gulf States Hemophilia and Thrombophilia Center at Houston, Houston, TX
³Hemophilia and Coagulation Disorders Program, University of Michigan, Ann Arbor, MI
⁴Clinical, Medical and Regulatory Affairs, Novo Nordisk Inc., Plainsboro, NJ

Jawed Fareed, PhD¹, Debra Hoppensteadt, PhD^1*, Daneyal Syed^1*, Daniel Kahn^1*, Michael Mosier^2*, Amanda Walborn^1* and Mark Williams^3*

¹Department of Pathology, Loyola University Medical Center, Maywood, IL
²Department of Surgery, Loyola University Medical Center, Maywood, IL
³Asahi Kasei Pharma America, Waltham, MA

Luigi Solimeno, MD^1*, Steven R. Lentz, MD, PhD², Irina Matytsina, MD^3*, Niels Zeuthen^4*, Faraizah Abdul Karim, MD^5* and Elena Santagostino, MD, PhD⁶

¹Department of Orthopedic Surgery and Traumatology, Ca' Grande Foundation, Maggiore Hosptial Policlinico, Milan, Italy
²University of Iowa Carver College of Medicine, Iowa City, IA
³Novo Nordisk A/S, Soeborg, Denmark
⁴Novo Nordisk A/S, Søborg, Denmark
⁵National Blood Center, Kuala Lumpur, Malaysia
⁶Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Ca' Granda Foundation, Maggiore Hospital Policlinico, Milan, Italy

Elena Varotto^1*, Giovanna Sanna^1*, Luca Spiezia^2*, Stefania Varotto, MD^3*, Marta Pillon, MD^4*, Laura Sainati, MD^1*, Alessandra Todesco^1*, Barbara Buldini, MD^5*, Maria Grazia Petris^1*, Raffaella Colombatti^1*, Manuela Tumino^1*, Giada Biddeci^1*, Antonio Marzollo^1*, Maria Gabelli^1*, Maria Paola Boaro^1*, Elena Campello^1*, Paolo Simioni, MD, PhD^6*, Giuseppe Basso, Prof, MD⁵ and Maria Caterina Putti, MD^3*

¹University of Padua, Department of Women’s and Chidren’s Health, Italy, University of Padua, Padua, Italy
²Department of Internal Medicine, University of Padua, Padua, Italy
³Department of Women’s and Chidren’s Health, University of Padua, Padua, Italy
⁴Department of Women's and Children's Health, University Hospital of Padova, Clinic of Pediatric Hemato-Oncology, Padova, Italy
⁵Woman and Child Health Department, University of Padova, Padova, Italy
⁶Medical & Surgical Sciences, Univ. of Padua, Med. School, Padova, Italy

Bhanu P Gupta, MD, MS^1*, Juan Leoni^1*, Parag Patel, MD^1*, Dong Chen, MD, PhD² and Joseph Blackshear, MD^3*

¹Transplant Cardiology, Mayo Clinic, Jacksonville, FL
²Hematohology, Mayo Clinic, Rochester, MN
³Cardiovascular Diseases, Mayo Clinic, Jacksonville, FL

Roshni Kulkarni¹, Amy D Shapiro, MD², Jerzy Windyga^3*, Margaret V Ragni⁴, K John Pasi⁵, Margareth Castro Ozelo, MD, PhD⁶, Elisa Tsao^7* and Baisong Mei^7*

¹Dept. Of Pediatrics and Human Development, Michigan State University, East Lansing, MI
²Indiana Hemophilia & Thrombosis Center, Indianapolis, IN
³Department of Disorders of Haemostasis and Internal Medicine, Institute of Haematology and Transfusion Medicine, Warsaw, Poland
⁴University of Pittsburgh and Hemophilia Center of Western PA, Pittsburgh, PA
⁵Barts and the London Comprehensive Care Center, London, United Kingdom
⁶INCT do Sangue Hemocentro UNICAMP, Campinas, Brazil
⁷Biogen, Cambridge, MA