-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

653A.O3.6 653. Myeloma: Therapy, excluding Transplantation: Next Generation Agents, Novel Combinations, and Amyloidosis

Myeloma: Therapy, excluding Transplantation Program: Oral and Poster Abstracts
Type: Oral
Monday, December 7, 2015: 2:45 PM-4:15 PM
Tangerine 2 (WF2), Level 2 (Orange County Convention Center)
Moderators:
Meletios A. Dimopoulos, National and Kapodistrian University of Athens and Jatin J. Shah, MD, The University of Texas MD Anderson Cancer Center

Disclosures:
Shah: Celgene: Consultancy , Research Funding .
2:45 PM

Philippe Moreau1*, Tamás Masszi, MD2, Norbert Grzasko, MD, PhD3*, Nizar J Bahlis, MD4, Markus Hansson5*, Ludek Pour, MD6*, Irwindeep Sandhu, MD7, Peter Ganly, BMBCh, PhD8*, Bartrum W Baker, MBChB, FRACP, FRCPA9, Sharon Jackson, MBChB, FRACP, FRCPA10, Anne-Marie Stoppa, MD11, David R Simpson, MBChB, FRACP, FRCPA12, Peter Gimsing, MD, DMSci13*, Antonio Palumbo14, Laurent Garderet, MD15, Michele Cavo16*, Shaji K. Kumar, MD17, Cyrille Touzeau, MD18*, Francis Buadi, MD17, Jacob P. Laubach, MD19, Jianchang Lin, PhD20*, Deborah Berg, RN, MSN20, Alessandra DiBacco, PhD20*, Ai-Min Hui, MD, PhD20 and Paul G. Richardson, MD21

1University of Nantes, Nantes, France
2Dept. of Haematology and Stem Cell Transplantation, St. István and St. László Hospital of Budapest, Budapest, Hungary
3Department of Haemato-oncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland
4University of Calgary, Southern Alberta Cancer Research Institute, Calgary, AB, Canada
5Department of Hematology, Skĺne University Hospital, Lund University, Lund, Sweden
6University Hospital Brno, Brno, Czech Republic
7Department of Medicine, Division of Hematology, University of Alberta, Edmonton, AB, Canada
8Department of Haematology, Christchurch Hospital, Christchurch, New Zealand
9Department of Haematology, Palmerston North Hospital, Palmerston North, New Zealand
10Department of Haematology, Middlemore Hospital, Auckland, New Zealand
11Department of Hematology, Institut Paoli-Calmettes, Marseille, France
12Department of Haematology, North Shore Hospital, Auckland, New Zealand
13Department of Hematology, University Hospital Rigshospitalet, Copenhagen, Denmark
14University of Torino, Torino, Italy
15Hôpital Saint Antoine, Paris, France
16Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy
17Division of Hematology, Mayo Clinic, Rochester, MN
18Nantes University Hospital, Hôtel Dieu, Nantes, France
19Dana-Farber Cancer Institute, Boston, MA
20Millennium Pharmaceuticals, Inc., Cambridge, MA, USA, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA
21Division of Hematologic Malignancy, Department of Medical Oncology, Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

3:00 PM

Jeffrey A Zonder, MD1, Saad Usmani2*, Emma C. Scott, MD3, Craig C. Hofmeister, MD4, Nikoletta Lendvai, MD PhD5, Jesus G. Berdeja, MD6, Larry D. Anderson Jr., MD, PhD7, Parameswaran Hari, MBBS, MD, MRCP8, Seema Singhal, M.D.9, Gregory Orloff, MD10, Michael Craig, MD11, Jason Valent, MD12, Wes Lee13*, Lowell Hart14*, J Hrom15*, Stephano Tarantolo16*, Edward Faber, DO17*, Gary J Schiller, MD18, Jennifer Schreiber, BS19*, Colleen Oliver, MSc19*, Selena A Rush, BS20*, Brian Tunquist21, Mieke Ptaszynski19* and Noopur S. Raje, MD22

1Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI
2Levine Cancer Institute/Carolinas Healthcare System, Charlotte, NC
3Center for Hematologic Malignancies, The Knight Cancer Institute, Oregon Health and Science University and the Knight Cancer Institute, Portland, OR
4The Ohio State University, Columbus, OH
5Memorial Sloan-Kettering Cancer Center, New York, NY
6Sarah Cannon Research Institute, Nashville, TN
7Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
8Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
9Robert H. Lurie Comprehensive Cancer Center, Division of Hem./Onc., Northwestern University Feinberg School of Medicine, Chicago, IL
10Fairfax Northern Virginia Hematology Oncology, Fairfax, VA
11West Virginia University Hospitals, Inc., Morgantown, WV
12Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
13St. Joseph Healthcare, Santa Rosa, CA
14Florida Cancer Specialists, Fort Myers, FL
15Forest General Cancer Center, Hattiesburg, MS
16Nebraska Cancer Specialists, Omaha, NE
17Oncology Hematology Care - Blue Ash, Cincinnati, OH
18University of California Los Angeles Medical Center, Los Angeles, CA
19Array BioPharma, Boulder, CO
20Array BioPharma Inc., Boulder, CO
21Array Biopharma, Boulder, CO
22Massachusetts General Hospital Cancer Center, Boston, MA

3:15 PM

Philippe Moreau1*, Douglas Joshua2, Wee-Joo Chng3, Antonio Palumbo4, Hartmut Goldschmidt5, Roman Hájek6, Thierry Facon7, Heinz Ludwig8, Ludek Pour, MD9*, Ruben Niesvizky10, Albert Oriol, MD11*, Laura Rosińol12*, Aleksandr Suvorov13*, Gianluca Gaidano14, Tomas Pika15*, Katja Weisel16*, Vesselina Goranova-Marinova17*, Heidi H. Gillenwater18, Nehal Mohamed18*, Shibao Feng18* and Meletios Dimopoulos19

1University of Nantes, Nantes, France
2Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
3National University Cancer Institute, National University Health System, Singapore, Singapore
4University of Torino, Torino, Italy
5Heidelberg Medical University, Heidelberg, Germany
6University Hospital Ostrava, Ostrava, Czech Republic
7CHRU Lille Hôpital Claude Huriez, Lille, Lille, France
8Department of Medicine I, Wilhelminenhospital, Wilhelminen Cancer Research Institute, Vienna, Austria
9University Hospital Brno, Brno, Czech Republic
10Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY
11Institut Catalŕ d’Oncologia, Institut Josep Carreras, Hospital Germans Trias i Pujol, Barcelona, Spain
12Hospital Clínic de Barcelona, Barcelona, Spain
13First Republican Clinical Hospital of Udmurtia, Izhevsk, Russia
14Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
15University Hospital Olomouc, Olomouc, Czech Republic
16Universitatsklinikum Tubingen, Tubingen, Germany
17University Multiprofile Hospital for Active Treatment, Plovdiv, Bulgaria
18Onyx Pharmaceuticals, Inc., an Amgen subsidiary, South San Francisco, CA
19National and Kapodistrian University of Athens, Athens, Greece

3:30 PM

Herve Avet-Loiseau1*, Cyrille Hulin2*, Lofti Benboubker3*, Meletios A. Dimopoulos4, Andrew Belch5, Donna Reece6, John Catalano7, Antonio Pinto8*, Heinz Ludwig9, Nizar J Bahlis10, Michele Cavo11*, Michel Attal12, Philippe Moreau13*, Lugui Qiu14*, Richard LeBlanc15, Rik Schots16*, S. Vincent Rajkumar17, Jennifer Marek18*, Guang Chen18*, Wai Yiu18*, Annette Ervin-Haynes18 and Thierry Facon19

1Unite de Genomique du Myelome, CHU Rangueil, Toulouse, France
2CHU BORDEAUX, Bordeaux, France
3CHU Tours Hopital Bretonneau, Tours, France
4National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
5Cross Cancer Institute, Edmonton, AB, Canada
6Princess Margaret Cancer Centre, Toronto, ON, Canada
7Frankston Hospital, Frankston, Victoria, Australia
8Hematology-Oncology and Stem Cell Transplantation Unit, Istituto Nazionale Tumori, Naples, Italy
9Department of Medicine I, Wilhelminenhospital, Wilhelminen Cancer Research Institute, Vienna, Austria
10Hematology and Bone Marrow Transplantation, University of Calgary, Tom Baker Cancer Centre, Calgary, AB, Canada
11Serŕgnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy
12CHU Toulouse Hopital Purpan, Toulouse, France
13Nantes University Hospital, Hôtel‐Dieu, Nantes, France
14Blood Disease Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China
15Division of Hematology and Medical Oncology, Department of Medicine, Maisonneuve-Rosemont Hospital, University of Montreal, Montreal, QC, Canada
16Myeloma Center, University Hospital VUB, Brussels, Belgium
17Division of Hematology, Mayo Clinic, Rochester, MN
18Celgene Corporation, Summit, NJ
19Maladies du Sang, Hôpital Claude Huriez, CHRU Lille, Lille, France

3:45 PM

Hervé Avet-Loiseau, MD1*, Rafael Fonseca, MD2, David S Siegel, MD, PhD3, Meletios A. Dimopoulos4, Ivan Spicka5*, Tamás Masszi6, Roman Hájek7, Laura Rosińol8*, Vesselina Goranova-Marinova9*, Georgi Mihaylov10*, Vladimír Maisnar11*, Maria-Victoria Mateos12, Michael Wang, MD13, Ruben Niesvizky, MD14, Albert Oriol15*, Andrzej Jakubowiak, MD, PhD16, Jiri Minarik17, Antonio Palumbo18, William Bensinger, MD19*, Vishal Kukreti20, Dina Ben-Yehuda21*, Margaret Tonda22*, Mihaela Obreja22* and Philippe Moreau23*

1Centre de Recherche en Cancérologie de Toulouse Institut National de la Santé, Toulouse, France
2Mayo Clinic, Scottsdale, AZ
3Hackensack University Medical Center, John Theurer Cancer Center, Hackensack, NJ
4National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
5Department of Internal Medicine, University Hospital, Praha, Czech Republic
6St István and St Laszlo Hospital, Budapest, Hungary
7University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
8Hospital Clínic de Barcelona, Barcelona, Spain
9Clinic University Multiprofile Hospital for Active Treatment, Plovdiv, Bulgaria
10Queen Joanna University Hospital, Sofia, Bulgaria
11Charles University Faculty Hospital and Faculty of Medicine, Hradec Králové, Czech Republic
12Hematology Department, University Hospital of Salamanca/IBSAL, Salamanca, Spain
13Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
14Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY
15Institut Catalŕ d’Oncologia, Institut Josep Carreras, Hospital Germans Trias i Pujol, Barcelona, Spain
16University of Chicago Medical Center, Chicago, IL
17University Hospital Olomouc, Olomouc, Czech Republic
18University of Torino, Torino, Italy
19Fred Hutchinson Cancer Research Center, Seattle, WA
20Princess Margaret Cancer Centre, Toronto, ON, Canada
21Hadassah-Hebrew University Medical Centre, Jerusalem, Israel
22Onyx Pharmaceuticals, Inc., an Amgen subsidiary, South San Francisco, CA
23University of Nantes, Nantes, France

4:00 PM

Ashutosh Wechalekar, MD, FRCPath, Carol Whelan, MD FRCP*, Helen Lachmann, MD FRCP*, Marianna Fontana, MD*, Shameem Mahmood, FRCPath*, Julian D Gillmore, MD PhD FRCP* and Philip N Hawkins, MD PhD FMedSci*

National Amyloidosis Centre, University College London, London, United Kingdom

*signifies non-member of ASH