-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

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Ticketed Session denotes that this is a ticketed session.

651.O2.6 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Clinical Insights from the Next Generation Characterization of Multiple Myeloma

Myeloma: Biology and Pathophysiology, excluding Therapy Program: Oral and Poster Abstracts
Type: Oral
Monday, December 7, 2015: 2:45 PM-4:15 PM
W224ABEF, Level 2 (Orange County Convention Center)
Moderators:
David Roodman, Indiana University School of Medicine and P. Leif Bergsagel, MD, PhD, Mayo Clinic

Disclosures:
No relevant conflicts of interest to declare.
2:45 PM

Paula Arana1*, Bruno Paiva, PhD2*, Noemi Puig, MD, PhD3*, Teresa Cedena4*, Lourdes Cordon5*, Maria Belen Vidriales, MD, PhD3*, Joaquin Martinez-López, MD.PhD6*, Enrique M. Ocio, MD, PhD7*, Miguel T Hernandez8*, Ana Isabel Teruel, MD9*, Mercedes Gironella10*, M Asuncion Echeveste11*, Laura Rosiñol, MD PhD12*, Rafael Martinez, MD PhD13*, Albert Oriol, MD PhD14*, Joan Blade, MD PhD12, Juan Jose Lahuerta15*, Maria-Victoria Mateos16 and Jesus San Miguel, MD PhD17*

1Clinica Universidad de Navarra, Pamplona, Spain
2Department of Hematology and Immunology, Clinica Universidad de Navarra, Pamplona, Spain
3Department of Hematology, Hospital Universitario de Salamanca, Salamanca, Spain
4Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
5Hospital Universitario La Fe, Valencia, Spain
6Hematology, Hospital 12 de Octubre, Madrid, Spain
7University Hospital of Salamanca, Salamanca, Spain
8Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
9Hospital Clinico de Valencia, Valencia, Spain
10Hospital Universitari Vall dHebron, Barcelona, Spain
11Hospital Universitario Donostia, San Sebastian, Spain
12Hospital Clinic de Barcelona, Barcelona, Spain
13Hospital Universitario San Carlos, Madrid, Spain
14Institut Català d’Oncologia, Hospital Germans Trias i Pujol, Barcelona, Spain
15Hospital 12 de Octubre, Madrid, Spain
16Hematology Department, University Hospital of Salamanca/IBSAL, Salamanca, Spain
17Centro de Investigación Médica Aplicada, University of Navarra, Clínica Universidad de Navarra, Pamplona, Spain

3:00 PM

Jonathan J Keats, PhD1, Gil Speyer1*, Legendre Christophe1*, Christofferson Austin1*, Kristi Stephenson, BS1*, Ahmet Kurdoglu1*, Megan Russell1*, Aldrich Jessica1*, Cuyugan Lori1*, Jonathan Adkins1*, Jackie McDonald1*, Adrienne Helland1*, Alex Blanski2*, Meghan Hodges2*, Dan Rohrer3*, Sundar Jagannath, MD4, David S Siegel, MD, PhD5, Ravi Vij, MD, MBA6, Gregory Orloff, MD7, Todd Zimmerman, MD8, Ruben Niesvizky, MD9, Darla Liles, MD10, Joseph W. Fay11, Jeffrey L. Wolf, MD, PhD12, Robert M. Rifkin13, Norma C Gutierrez14*, The MMRF CoMMpass Network15*, Jen Toups15*, Mary Derome, MS15*, Winnie Liang, PhD1*, Seunchan Kim1*, Daniel Auclair, PhD15*, Pamela G. Kidd, MD16, Scott Jewell, PhD2*, John David Carpten, PhD1* and Sagar Lonial, MD17,18

1Translational Genomics Research Institute, Phoenix, AZ
2Van Andel Research Institute, Grand Rapids, MI
3Van Andel Research Institute, Phoenix, AZ
4Tisch Cancer Institute / Multiple Myeloma Program, Mount Sinai School of Medicine, New York, NY
5Hackensack University Medical Center, John Theurer Cancer Center, Hackensack, NJ
6Department of Medicine, Division of Oncology, Washington University School of Medicine, St Louis, MO
7Fairfax Northern Virginia Hematology Oncology, Fairfax, VA
8University of Chicago Medical Center, Chicago, IL
9Center of Excellence for Lymphoma and Myeloma, Weill Cornell Medical College, New York, NY
10Department of Hematology/Oncology, Brody School of Medicine at East Carolina University, Greenville, NC
11Baylor Univ. Medical Ctr., Dallas, TX
12University of California San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA
13Rocky Mountain Cancer Centers, Denver, CO
14Hematology, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain
15Multiple Myeloma Research Foundation, Norwalk, CT
16Spectrum Health, Grand Rapids, MI
17Winship Cancer Institute, Emory University, Atlanta, GA
18Winship Cancer Institute of Emory University, Department of Hematology and Medical Oncology, Atlanta, GA

3:15 PM

Elias Karl Mai, MD1*, K. Martin Kortuem, MD2*, Nur Hanafiah1*, Santiago Barrio3*, Laura Ann Bruins3*, Maximilian Merz, MD4*, Jing Xu5*, Koenuel Pashayeva, MD1*, Yuan-Xiao Zhu2*, Chang-Xin Shi, PhD2*, R. Alexander Stewart2*, Patrick Jedlowski2*, Mindaugas Andrulis, MD5*, Anna Jauch, Prof.6*, Jens Hillengass, MD7, Hartmut Goldschmidt, MD1,8, P. Leif Bergsagel, MD, PhD2, Esteban Braggio, PhD2, A. Keith Stewart, MD3,9 and Marc Steffen Raab, MD, PhD1,10

1Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany
2Division of Hematology/Oncology, Mayo Clinic, Scottsdale, AZ
3Mayo Clinic, Scottsdale, AZ
4Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany
5Institute of Pathology, University Clinic Heidelberg, Heidelberg, Germany
6Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany
7Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany
8National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany
9Oncospire Inc., Rochester, MN
10Max Eder Group for Experimental Therapies for Hematologic Malignancies, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany

3:30 PM

James E McDonald1*, Marcus M Kessler1*, Michael Gardner2*, Amy Buros, PhD3*, Sarah Waheed, MD3*, James Ntambi1*, Frits van Rhee, MD, PhD3, Maurizio Zangari, MD3, Christoph Heuck, MD3, Nathan Petty, MS3*, Carolina Schinke, MD3*, Sharmilan Thanendrarajan, MD3, Alan Mitchell4*, Antje Hoering4*, Bart Barlogie, MD, PhD3, Gareth J Morgan, MD, PhD3 and Faith E Davies, MD3

1Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR
2College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR
3Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR
4Cancer Research and Biostatistics, Seattle, WA

3:45 PM

Bruno Paiva, PhD1*, Maria Belen Vidriales, MD, PhD2*, Noemi Puig, MD, PhD2*, Teresa Cedena3*, Lourdes Cordon4*, Maria-Victoria Mateos5, Joaquin Martinez-López, MD.PhD6*, Laura Rosiñol, MD PhD7*, Alfonso Garcia de Coca, MD, PhD8*, Natalia De Las Heras, MD9*, Josefina Galende10*, Jose Mariano Hernandez, MD11*, Luis Palomera, MD PhD12*, Javier De La Rubia13*, Joan Blade, MD PhD7, Jesus San Miguel, MD PhD14* and Juan Jose Lahuerta15*

1Department of Hematology and Immunology, Clinica Universidad de Navarra, Pamplona, Spain
2Department of Hematology, Hospital Universitario de Salamanca, Salamanca, Spain
3Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
4Hospital Universitario La Fe, Valencia, Spain
5Hematology Department, University Hospital of Salamanca/IBSAL, Salamanca, Spain
6Hematology, Hospital 12 de Octubre, Madrid, Spain
7Hospital Clinic de Barcelona, Barcelona, Spain
8Hospital Clínico Universitario de Valladolid, Valladolid, Spain
9Complejo Hospitalario de Leon, Leon, Spain
10Hospital Comarcal del Bierzo, Ponferrada, Spain
11Hospital General de Segovia, Segovia, Spain
12Department of Hematology, Hospital Universitario Lozano Blesa, Zaragoza, Spain
13H.U.P. La Fe, Valencia, Spain
14Centro de Investigación Médica Aplicada, University of Navarra, Clínica Universidad de Navarra, Pamplona, Spain
15Hospital 12 de Octubre, Madrid, Spain

4:00 PM

Mariateresa Fulciniti1, Mehmet Kemal Samur, PhD2*, Naim Ur Rashid, PhD3*, Rajya Lakshmi Bandi, MS4*, Manoj Bhasin, PhD5*, Giovanni Parmigiani, PhD2*, Kenneth C Anderson, MD6 and Nikhil C. Munshi, MD6,7

1The Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
2Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
3Dana Farber, Boston
4Dana Farber Cancer Institute, Boston, MA
5BIDMC Genomics, Proteomics, Bioinformatics and Systems Biology Center, Boston, MA
6LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
7VA Medical Hospital, Boston, MA

*signifies non-member of ASH