Aziz Nazha, MD¹, Mayur Subhash Narkhede, MD², Tomas Radivoyevitch, PhD^3*, Matt Kalaycio, MD⁴, Bhumika J. Patel^5*, Aaron T. Gerds, MD, MS⁶, Sudipto Mukherjee, MD, PhD⁶, Michael Clemente, MS^7*, Cassandra M Hirsch^8*, Anjali S. Advani, MD⁶, Bartlomiej Przychodzen, MSc^9*, Hetty E. Carraway, MD, MBA⁶, Jaroslaw P. Maciejewski, MD, Ph.D.⁵ and Mikkael A. Sekeres, MD, MS⁶

¹Leukemia Program, Department of Hematology and Oncology, Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
²Leukemia Program, Department of Hematology and Oncology, Cleveland Clinic, Cleveland, OH
³Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH
⁴Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁵Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁶Leukemia Program, Cleveland Clinic, Cleveland, OH
⁷Experimental Hematology and Hematopoiesis, Cleveland Clinic Foundation, Cleveland, OH
⁸Department of Translational Hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, Cleveland, OH
⁹Haematological Medicine, Department of Translational hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, London, United Kingdom

Vera Ademà, MSc^1*, Laura Palomo, MSc^1*, Przychodzen P Bartlomiej^2*, Diez-campelo Maria, MD^3*, Naoko Hosono, MD, PhD^4*, Mar Mallo, PhD^1*, Blanca Xicoy, MD, PhD^5*, Elisa Luño^6*, Bhumika J. Patel^7*, Cassandra M Hirsch^8*, Lurdes Zamora, PhD^5*, Thomas LaFramboise, PhD^9*, Leonor Arenillas, MD^10*, Albert Perez-Ladaga, PhD^11*, Carme Pedro^12*, Michael J. Clemente^8*, Joan Bargay, MD^13*, Julia Montoro, MD^14*, Juan Carlos Caballero, MD^3*, Brayan Merchan, MD^15*, Victor Noriega, MD^16*, Victor Marcos-Betes, MD^17*, Consuelo Del Cañizo, MD, PhD¹⁸, Rosario Lopez, PhD^19*, José María Raya, MD^20*, Joaquin Sanchez-Garcia, MD^21*, Eduardo Rios^22*, Montserrat Arnan, MD, PhD^23*, Lourdes Florensa, MD, PhD^10*, Raquel de Paz^24*, Angelina Lemes, MD^25*, Paula Gomez-Marzo, MSc^1*, Nuri Haro^1*, Francisco Fuster-Tormo, MSc^1*, Monica Bayes, PhD^26*, Ivo Gut^27*, Rafael Bejar, MD, PhD¹¹, Mikkael A. Sekeres, MD, MS²⁸, Jaroslaw P. Maciejewski, MD, Ph.D.⁷ and Francesc Sole, PhD²⁹

¹MDS Research Group, Institut de Recerca Contra la Leucèmia Josep Carreras, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain
²Department of Translational hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, Cleveland, OH
³Servicio de Hematología, Centro de Investigación del Cáncer, IBSAL (Instituto de Biomedicina de Salamanca) y BMCC, Universidad de Salamanca, Salamanca, Salamanca, Spain
⁴Department of Hematology and Oncology, University of Fukui, Fukui, Japan
⁵Hematology Service, ICO-Hospital Germans Trias i Pujol, Institut de Recerca Contra la Leucèmia Josep Carreras, Universitat Autònoma de Barcelona, Badalona, Spain
⁶Hospital Universitario Central Asturias, Oviedo, Spain
⁷Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁸Department of Translational Hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, Cleveland, OH
⁹Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH
¹⁰Hematological Cytology Laboratory, Hospital del Mar, GRENTHE, IMIM (Hospital del Mar Research Institute), Barcelona, Spain
¹¹UCSD Moores Cancer Center, La Jolla, CA
¹²Servei d’Hematologia Clínica, Hospital del Mar, GRETNHE, IMIM, Barcelona, Barcelona, Spain
¹³Department of Hematology. Hospital Son Llatzer, Palma de Mallorca, Spain
¹⁴Hospital Vall d'Hebrón, Barcelona, Spain
¹⁵Servei de Hematologia. Hospital Vall d’Hebron, Barcelona, Spain
¹⁶Servicio de Hematologia, Complejo hospitalario universitario A Coruña - Sergas, A Coruna, Spain
¹⁷H Arnau de Vilanova de Lleida, Lleida, Spain
¹⁸Servicio de Hematología, Centro de Investigación del Cáncer, IBSAL (Instituto de Biomedicina de Salamanca) y BMCC, Universidad de Salamanca, Salamanca, Spain
¹⁹Hospital Althaia, Manresa, Spain
²⁰Hospital Universitario de Canarias, Tenerife, Spain
²¹Servicio de Hematología. Hospital Reina Sofía, Cordoba, Spain
²²Haematology Service, Hospital Universitario Virgen de Valme, Sevilla, Spain
²³Institut Català d'Oncologia, Hospital Duran i Reynals, Barcelona, Spain
²⁴Servicio de Hematología. Hospital La Paz, Madrid, Spain
²⁵Hospital Dr. Negrín, Las Palmas de Gran Canaria, Las Palmas, Spain
²⁶Centro Nacional de Análisis Genómico, Parc Científic de Barcelona, Barcelona, Spain
²⁷CNAG, Barcelona, Spain
²⁸Leukemia Program, Cleveland Clinic, Cleveland, OH
²⁹Josep Carreras Leukaemia Research Institute, Barcelona, Spain

Andrea Kuendgen, MD^1*, Heinz Tuechler^2*, Meritxell Nomdedeu^3*, Guillermo Garcia-Manero, MD⁴, Rami S. Komrokji, MD⁵, Mikkael A. Sekeres, MD, MS⁶, Matteo Giovanni Della Porta, MD^7*, Alan F List, MD⁸, Mario Cazzola⁷, Amy E. DeZern, MD, MHS⁹, Gail J. Roboz, MD¹⁰, David P. Steensma, MD¹¹, Arjan A van de Loosdrecht, MD, PhD¹², Arjan A van de Loosdrecht, MD, PhD¹², Richard F. Schlenk, MD¹³, Xavier Calvo^14*, Sabine Blum^15*, Arturo Pereira^3*, Peter Valent, MD¹⁶, Dolors Costa^3*, Aristoteles Giagounidis, MD, PhD¹⁷, Luis Benlloch^18*, Uwe Platzbecker, MD¹⁹, Carmen Pedro, MD^20*, Michael Lübbert, MD^21*, Maria Teresa Cedena^22*, Sigrid Machherndl-Spandl, MD²³, Maria Lopez-Pavia, MD^18*, Detlef Haase, MD^24*, Ana Africa Martin^25*, Claudia D Baldus, MD²⁶, Montserrat Martínez de Sola^27*, Reinhard Stauder, MD, MSc^28*, Brayan Merchan, MD^29*, Claudia Mende^1*, María Teresa Ardanaz, MD^30*, Christina Ganster^31*, Francesc Cobo^32*, Thomas Schroeder, MD^1*, Jordi Esteve³³, Rainer Haas, MD^1*, Nomdedeu Benet^3*, Peter L. Greenberg, MD³⁴, Ulrich Germing, MD^1* and Guillermo Sanz, MD, PhD³⁵

¹Department of Hematology, Oncology, and Clinical Immunology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany
²Boltzmann Institute for Leukemia Research, Hanusch Hospital, Vienna, Austria
³Hospital Clinic, Spanish MDS Cooperative Group, Barcelona, Spain
⁴Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, Houston, TX
⁵Malignant Hematology Department, H Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁶Leukemia Program, Cleveland Clinic, Cleveland, OH
⁷Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
⁸Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁹Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
¹⁰Division of Hematology / Oncology, Weill Cornell Medical College, New York, NY
¹¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
¹²Department of Hematology, VU University Medical Center, Amsterdam, Netherlands
¹³Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
¹⁴Hospital del Mar, Spanish MDS Cooperative Group, Barcelona, Spain
¹⁵Haematology Service, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
¹⁶Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria
¹⁷Marien Hospital Düsseldorf, Düsseldorf, Germany
¹⁸Hospital Universitario La Fe, GESMD, Valencia, Spain
¹⁹Carl Gustav Carus an der Technischen Universität, Universitätsklinikum, Dresden, Germany
²⁰Department of Hematology, Hospital del Mar, Barcelona, Spain
²¹Div. Hematology, Oncology and Stem Cell Transplantation, University of Freiburg, Freiburg, Germany
²²Hospital 12 de Octubre, Madrid, Spain
²³Department of Hematology and Oncology, Elisabethinen Hospital, Linz, Austria
²⁴Department of Hematology and Medical Oncology, Universitätsmedizin Göttingen, Göttingen, Germany
²⁵Hospital Universitario de Salamanca, Salamanca, Spain
²⁶Department of Hematology and Oncology, Charité University Hospital, Berlin, Germany
²⁷Hospital Parc Tauli, Sabadell, Spain
²⁸Department of Internal Medicine V (Hematology and Oncology), Innsbruck Medical University, Innsbruck, Austria
²⁹Servei de Hematologia. Hospital Vall d’Hebron, Barcelona, Spain
³⁰Hospital de Txagorritxu, Vitoria, Spain
³¹Department of Hematology and Medical Oncology, Georg-August-University Göttingen, Göttingen, Germany
³²Hospital Teknon, Barcelona, Spain
³³Hospital Clinic de Barcelona, Spanish MDS Cooperative Group, Barcelona, Spain
³⁴Division of Hematology, Stanford University Medical Center, Stanford, CA
³⁵Hospital Universitario La Fe, Spanish MDS Cooperative Group, Valencia, Spain

Geoffrey L. Uy, MD¹, Eric J. Duncavage, MD², Gue Su Chang, PhD^3*, Meagan A. Jacoby, MD, PhD¹, Christopher A. Miller, PhD^3*, Jin Shao^1*, Sharon Heath^1*, Robert S. Fulton, PhD^3*, Catrina C. Fronick^3*, Michelle O'Laughlin^3*, Camille N. Abboud, MD¹, Amanda F. Cashen, MD¹, John F. DiPersio, MD, PhD¹, Richard K Wilson, PhD^3*, Daniel C. Link, MD⁴, John S. Welch, MD, PhD¹, Peter Westervelt, MD, PhD¹, Timothy J. Ley, MD¹, Timothy A. Graubert, MD⁵ and Matthew J. Walter, MD¹

¹Division of Oncology, Washington University School of Medicine, St. Louis, MO
²Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO
³McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO
⁴Division of Oncology, Department of Internal Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO
⁵Massachusetts General Hospital / Harvard Medical School, Boston, MA

Aziz Nazha, MD¹, Bartlomiej Przychodzen, MSc^2*, Hideki Makishima, MD, Ph.D.³, Hetty E. Carraway, MD, MBA⁴, Bhumika J. Patel^5*, Cassandra M Hirsch^6*, Michael Clemente, MS^7*, Srinivasa R. Sanikommu, MBBS⁸, Aaron T. Gerds, MD, MS⁴, Jennifer S. Carew, Ph.D.⁵, Satoru Miyano, MD, Ph.D.^9*, Matt Kalaycio, MD¹⁰, Seishi Ogawa, MD, Ph.D.³, Jaroslaw P. Maciejewski, MD, Ph.D.⁵ and Mikkael A. Sekeres, MD, MS⁴

¹Leukemia Program, Department of Hematology and Oncology, Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
²Haematological Medicine, Department of Translational hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, London, United Kingdom
³Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
⁴Leukemia Program, Cleveland Clinic, Cleveland, OH
⁵Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁶Department of Translational Hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, Cleveland, OH
⁷Experimental Hematology and Hematopoiesis, Cleveland Clinic Foundation, Cleveland, OH
⁸Cleveland Clinic Taussing Cancer Institute, Cleveland, OH
⁹Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
¹⁰Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Christopher Pleyer, MD¹, Surbhi Sidana, MD², Tomas Radivoyevitch, PhD^3*, Remco Molenaar, MD^4*, Andrew Godley, PhD^5*, Erik Offerman^6*, Anjali S. Advani, MD⁷, Aaron T. Gerds, MD, MS⁷, Hetty E. Carraway, MD, MBA⁷, Matt Kalaycio, MD⁸, Jaroslaw P. Maciejewski, MD, Ph.D.⁹, Mikkael A. Sekeres, MD, MS⁷ and Sudipto Mukherjee, MD, PhD⁷

¹Department of Internal Medicine, Cleveland Clinic, Cleveland, OH
²Department of Hematology and Medical Oncology, Mayo Clinic, Rochester, MN
³Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH
⁴Department of Cell Biology & Histology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
⁵Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁶Lerner College of Medicine, Cleveland Clinic, Cleveland, OH
⁷Leukemia Program, Cleveland Clinic, Cleveland, OH
⁸Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁹Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH