Philippe Rousselot, MD, PhD^1,2,3*, Hyacinthe Johnson-Ansah, MD^3,4*, Françoise Huguet, MD^3,5,6*, Laurence Legros, MD^3,7*, Martine Escoffre-Barbe^3,8*, Martine Gardembas, MD^3*, Pascale Cony-Makhoul, MD^3,9*, Valérie Coiteux, MD^3,10*, Laurent Sutton, MD^11*, Wajed Abarah, MD^3,12*, Camille Pouaty, MD^3,13*, Jean Michel Pignon, MD^3,14*, Bachra Choufi, MD^3,15*, Sorin Visanica, MD^3,16,17*, Bénédicte Deau, MD^3,18*, Stephane Bouchet, MD PhD^19*, Francois Guilhot, MD^3,20, Francois-Xavier Mahon, MD, PhD, Professor^3,21,22*, Laure Morisset^23*, Jean-Michel Cayuela^3,24* and Benjamin Maneglier, MD^25*

¹Hematology Department, Hôpital André Mignot, Versailles, France
²University of Versailles St-Quentin-en-Yvelines, Versailles, France
³Fi-LMC group, Pessac, France
⁴Hematology department, CHU Caen, Caen, France
⁵CHU Toulouse, Toulouse, France
⁶Hematology department, Institut universitaire du cancer de Toulouse, Toulouse, France
⁷Hematology department, Hopital Archet 1, CHU Nice, Nice, France
⁸Hematology department, Hôpital Pontchaillou, CHU Rennes, Rennes, France
⁹Centre Hospitalier Annecy Genevois, Pringy, France
¹⁰Hematology department, Hôpital Claude Huriez, Lille, France
¹¹Hematology Department, Argenteuil Hospital, Argenteuil, France
¹²Hospital, Meaux, France
¹³Centre hospitalier de Dieppe, Dieppe, France
¹⁴Haematology, CH Dunkerque, Dunkerque, France
¹⁵Hôpital de Boulogne-sur-Mer, Boulogne-sur-Mer, France
¹⁶Hôpital Bons Secours, Metz, France
¹⁷CH de METZ, Metz, France
¹⁸Hôpital Cochin AP-HP, Paris, France
¹⁹Pharmacology, Universite Victor Segalen Bordeaux 2, Bordeaux, France
²⁰Clinical Investigation Center, INSERM CIC 1402, CHU de Poitiers, Poitiers, France
²¹Hematology department, Institut Bergonié, Bordeaux, France
²²Inserm U1035, Université Bordeaux Segalen, Bordeaux, France
²³Clinical research center, Hôpital Mignot, Le Chesnay, France
²⁴Hematology, Hôpital Saint-Louis, Paris, France
²⁵Pharmacology, Hôpital Mignot, Le Chesnay, France

Lydia ROY, MD^1,2*, Jean-Claude Chomel, PharmD PhD^3*, Joelle Guilhot, PhD⁴, Agnes Guerci-Bresler, MD^5*, Martine Escoffre-Barbe^6*, Stéphane Giraudier, MD, PhD^7*, Aude Charbonnier^8*, Viviane Dubruille, MD^9*, Françoise Huguet^10*, Hyacinthe Johnson-Ansah, MD^11*, Pascal Lenain, MD^12*, Shanti Amé, MD^13*, Gabriel Etienne, MD, PhD^14*, Franck E. Nicolini¹⁵, Delphine Rea, MD, PhD^16*, Pascale Cony-Makhoul, M.D.^17*, Stephane Courby, MD^18*, Jean-Christophe Ianotto, MD^19*, Laurence Legros, MD^20*, Martine Delain, MD^21*, Valérie Coiteux, MD^22*, Eric Hermet, MD^23*, Martine Gardembas, MD^24*, Mathieu Molimard, MD, PhD^25*, Jean-Michel Cayuela^26*, Marie Thibaud, CRA^27*, Sophie Duranton, PharmD^28*, Francois-Xavier Mahon, MD, PhD^29*, Philippe Rousselot, MD, PhD, Professor^30* and Francois Guilhot, MD⁴

¹INSERM CIC 1402, CHU Poitiers, Poitiers, France
²Hematology department, Hôpital Henri Mondor, APHP, Créteil, France
³Molecular biology department, CHU Poitiers, Poitiers, France
⁴Clinical Investigation Center, INSERM CIC 1402, CHU de Poitiers, Poitiers, France
⁵Hematology department, Hôpital d'Adultes du Brabois, CHU Nancy, Nancy, France
⁶Hematology department, Hôpital Pontchaillou, CHU Rennes, Rennes, France
⁷Hematology Laboratory, Hôpital Henri Mondor, APHP, Créteil, France
⁸Hematology department, Institut Paoli Calmettes, Marseille, France
⁹Department of Hematology, Nantes University Hospital, Nantes, France
¹⁰Hematology, Institut Universitaire du Cancer, Toulouse, France
¹¹Hematology department, CHU Caen, Caen, France
¹²Hematology department, Centre Henri Becquerel, Rouen, France
¹³Hematology department, Hôpital Civil , CHU Strasbourg, Strasbourg, France
¹⁴Hematology department, Institut Bergonié, Bordeaux, France
¹⁵Hématologie, Centre Hospitalier Lyon Sud, Pierre Benite, & INSERM, Lyon, France
¹⁶Adult hematology department, Hôpital Saint-Louis, APHP, Paris, France
¹⁷Hematology department, Centre Hospitalier Annecy-Genevois, Site Annecy, Metz-Tessy, France
¹⁸Hematology department, CHU Grenoble, Grenoble, France
¹⁹Hematology department, institute of oncology and Hematology, Morvan Hospital, CHRU Brest, Brest, France
²⁰Hematology department, Hopital Archet 1, CHU Nice, Nice, France
²¹Hematology department, Hôpital Bretonneau, CHU Tours, Tours, France
²²Hematology department, Hôpital Claude Huriez, CHRU Lille, Lille, France
²³Hematology department, CHU d’Estaing, Clermont-Ferrand, France
²⁴Hematology department, University Hospital, Angers, France
²⁵Pharmacology department, INSERM U657, CHU Bordeaux, Bordeaux, France
²⁶Hematology, Hôpital Saint-Louis, Paris, France
²⁷Clinical Investigation Center, INSERM CIC 1402, CHU Poitiers, Poitiers, France
²⁸Pharmacovigilance, CHU Poitiers, Poitiers, France
²⁹Hematology laboratory, Hôpital Pellegrin, CHU Bordeaux, Bordeaux, France
³⁰Hematology department, Hôpital André Mignot, Versailles, France

Georg-Nikolaus Franke, MD^1*, Jacqueline Maier, PhD^1*, Kathrin Wildenberger^1*, Michael Cross, PhD^1*, Oliver Frank, PhD^2*, Frank Giles, MD MB^3*, Andreas Hochhaus, MD⁴, Christian T. Dietz, PhD^5*, Martin C. Müller^5*, Dietger Niederwieser, MD¹ and Thoralf Lange, MD^1,6*

¹Abteilung für Hämatologie/Onkologie, Universität Leipzig, Leipzig, Germany
²Novartis Pharma GmbH, Nuernberg, Germany
³NMDTI, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
⁴Universitätsklinikum Jena, Jena, Germany
⁵III. Medizinische Klinik, Medizinische Fakultät Mannheim der Ruprechts-Karl-Universität Heidelberg, Mannheim, Germany
⁶Asklepios Klinikum Weißenfels, Weißenfels, Germany

Alice Huang^*, Jennifer Salcius, MBA, MS^*, Connie Wong, PhD^*, Stephane Wong and Sha-Sha Wang, PhD^*

Novartis Companion Diagnostics, Cambridge, MA

Marc G Berger, MD, PhD, Professor^1,2,3, Bruno Pereira, PhD^4*, Charlotte Oris, PhD^1*, Sandrine Saugues^1*, Pascale Cony-Makhoul, MD^3,5*, Martine Gardembas, MD^3,6*, Laurence Legros, MD^3,7*, Martine Escoffre-Barbe^3,8*, Franck E. Nicolini, MD, PhD^3,9, Philippe Rousselot, MD, PhD, Professor^3,10*, Delphine Rea, MD, PhD^3,11*, Joelle Guilhot, PhD^3,12, Marie Zénut, MD, PhD^13*, Agnès Guerci, MD, PhD^3,14*, Stephane Giraudier, MD, PhD, Professor^3,15* and Francois-Xavier Mahon, MD, PhD, Professor^3,16*

¹Hematology (Biology), CHU Clermont-Ferrand, Clermont-Ferrand, France
²CHU Clermont-Ferrand, Haematology department, Clermont-Ferrand, France
³Fi-LMC group, Pessac, France
⁴Direction de la Recherche Clinique et de l'Innovation, CHU Clermont-Ferrand, Clermont-Ferrand, France
⁵CHANGE, PRINGY CEDEX, France
⁶Hematology department, University Hospital, Angers, France
⁷Hematology department, Hopital Archet 1, CHU Nice, Nice, France
⁸Hematology, Hôpital Pontchaillou, Rennes, France
⁹Centre Hospitalier Lyon Sud, Pierre-Bénite, France
¹⁰University of Versailles St-Quentin-en-Yvelines, Versailles, France
¹¹Adult hematology department, Hôpital Saint-Louis, APHP, Paris, France
¹²Inserm CIC 1402, University Hospital, Poitiers, France
¹³Centre Régional de Pharmacovigilance, CHU Clermont-Ferrand, Clermont-Ferrand, France
¹⁴Hématologie Clinique, CHU Nancy-Brabois, Vandoeuvre, France
¹⁵Hôpital Henri-Mondor, Créteil, France
¹⁶Laboratory of Hematology, Hôpital haut Lévêque, Pessac, France

Oliver G. Ottmann, MD^1*, Giuliana Alimena², Daniel J. DeAngelo, MD, PhD³, Yeow-Tee Goh, MBBS, MMed⁴, Michael C. Heinrich, MD⁵, Andreas Hochhaus, MD⁶, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA⁷, Francois-Xavier Mahon, MD, PhD, Professor^8*, Michael J. Mauro, MD⁹, Hironobu Minami, MD, D.Med.Sci.^10*, Marie Huong Nguyen, MD^11*, Delphine Rea^12*, Juan Luis Steegmann, MD¹³, Arkendu Chatterjee^14*, Varsha Iyer^14*, Noelia Martinez^14*, Gary J. Vanasse, MD¹⁴ and Kim Dong-Wook, MD, PhD^15*

¹Department of Haematology, Cardiff University, Cardiff, United Kingdom
²Department of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Italy
³Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁴Department of Clinical Research, Singapore General Hospital, Singapore, Singapore
⁵Oregon Health & Science University, Portland, OR
⁶Abteilung Hämatologie/Onkologie, Universitätsklinikum Jena, Jena, Germany
⁷SA Pathology and South Australian Health and Medical Research Institute, University of Adelaide, Adelaide, Australia
⁸Laboratoire Hématopoïèse Leucémique et Cible Thérapeutique, Inserm U1035, Université Victor Ségalen, Bordeaux, France
⁹Memorial Sloan Kettering Cancer Center, New York, NY
¹⁰Kobe University School of Medicine, Kobe, Japan
¹¹Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
¹²Service des Maladies du Sang et EA3518, Hôpital Saint-Louis, Paris, France
¹³Hematology Dpt. IIS-IP, Hospital Universitario de la Princesa, Madrid, Spain
¹⁴Novartis Institutes for BioMedical Research, Inc., Cambridge, MA
¹⁵Seoul St. Mary's Hospital, Catholic University of Korea, Seoul, South Korea