Mohamad Jawhar^1*, Juliana Schwaab, MD^1*, Susanne Schnittger, PhD², Manja Meggendorfer, PhD^2*, Karl Sotlar, MD^3*, Hans-Peter Horny, MD^4*, Georgia Metzgeroth, MD^5*, Sebastian Kluger^1*, Nicole Naumann^1*, Claudia Haferlach, MD², Torsten Haferlach², Peter Valent, MD⁶, Wolf-Karsten Hofmann, MD⁵, Alice Charlotte Fabarius, PhD^5*, Nicholas C.P. Cross, PhD⁷ and Andreas Reiter, MD^8*

¹Department of Hematology and Oncology, University Medical Centre Mannheim, Germany, Mannheim, Germany
²MLL Munich Leukemia Laboratory, Munich, Germany
³Ludwig-Maximilians-University Munich, Munich, Germany
⁴Pathology institute, Ludwig Maximillian’s University, Munich, Germany
⁵Department of Hematology and Oncology, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany
⁶Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
⁷Wessex Regional Genetics Laboratory, University of Southampton, Salisbury, United Kingdom
⁸Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany

Ayalew Tefferi, MD¹, Terra L. Lasho, PhD^2*, Christy Finke, BS^3*, Yoseph Elala, MD^4*, Daniela Barraco, MD^5*, Naseema Gangat, MBBS², Curtis A. Hanson, MD⁶, Rhett P. Ketterling, MD^7* and Animesh Pardanani, MBBS, PhD⁸

¹Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
²Division of Hematology, Mayo Clinic, Rochester, MN
³Hematology, Mayo Clinic, Rochester, MN
⁴Mayo Clinic, Rochester
⁵Mayo Clinic, Rochester, MN
⁶Division of Hematopathology, Mayo Clinic, Rochester, MN
⁷Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁸Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN

Paola Guglielmelli, MD, PhD^1,2*, Giada Rotunno^1,2*, Annalisa Pacilli, PhD^1,2*, Elisa Rumi, MD^3*, Vittorio Rosti, MD⁴, Federica Delaini, MD^5*, Margherita Maffioli, MD^6*, Tiziana Fanelli, MSc^2*, Alessandro Pancrazzi, BS^1,2*, Lisa Pieri, MD, PhD^1,7*, Raimonda Fjerza, MD^1,2*, Daniela Pietra, PhD^3*, Daniela Cilloni, MD⁸, Francesco Passamonti^9*, Alessandro Rambaldi, MD¹⁰, Giovanni Barosi, MD⁴, Tiziano Barbui, MD^11*, Mario Cazzola, MD¹² and Alessandro M. Vannucchi, MD^1,13

¹Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
²CRIMM-Centro Ricerca e Innovazione delle Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy
³Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁴Center for the Study of Myelofibrosis, Biotechnology Research Area, IRCCS Policlinico San Matteo Foundation, Pavia, Italy
⁵Hematology and Bone Marrow Transplant Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy
⁶Division of Hematology, Ospedale di Circolo - Fondazione Macchi Università degli Studi dell'Insubria, Varese, Italy
⁷Azienda Ospedaliera-Universitaria Careggi, University of Florence, Florence, Italy
⁸Dept Hematology and Clinical and Biological Sciences, University of Turin, S Luigi Hospital, Turin, Italy
⁹Ospedale di Circolo e Fondazione Macchi, Varese, Italy
¹⁰Department of Hematology, Hospital Papa Giovanni XXIII, Bergamo, Italy
¹¹Hospital Papa Giovanni XXIII and Research Foundation, Bergamo, Italy
¹²Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Pavia, Italy
¹³University of Florence, Florence, Italy

Nicolaus Kroeger, M.D.¹, Victoria Panagiota, M.D.^2*, Tatjana Zabelina, M.D.^1*, Michelle Maria Araujo Cruz, M.D.^2*, Rabia Shahswar, M.D.^2*, Anita Badbaran^1*, Ioanna N Triviai, PhD^1*, Francis Ayuk, M.D.^3*, Marten Gehlhaar, M.D.^2*, Christine Wolschke, M.D.^1*, Robin Bollin, M.D.^2*, Ulrich Lehmann, M.D.^4*, Christian Koenecke, M.D.^2*, Anuhar Chaturvedi, PhD, MS, BPharm^2*, Haefaa Alchalby, M.D.^1*, Michael Stadler, MD^2*, Matthias Eder, M.D.^2*, Maximilian Christopeit, M.D.^1*, Gudrun Göhring, M.D.^5*, Michael Koenigsmann, M.D.⁶, Brigitte Schlegelberger, MD, Prof.⁵, Hans Heinrich Kreipe, M.D.^4*, Arnold Ganser, M.D.⁷, Boris Fehse, PhD^1*, Felicitas Thol, MD⁷ and Michael Heuser, M.D.²

¹Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
²Hematology, Hemostasis, Oncology and SCT, Hannover Medical School, Hannover, Germany
³University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⁴Institute of Pathology, Hannover Medical School, Hannover, Germany
⁵Institute of Human Genetics, Hannover Medical School, Hannover, Germany
⁶Outpatient Oncology Center, Hannover Medical School, Hannover, Germany
⁷Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

Paola Guglielmelli, MD, PhD^1,2*, Annalisa Pacilli, PhD^1,2*, Giada Rotunno, MSc^1,2*, Francesca Gesullo, BS^1,2*, Alessandro Pancrazzi, BS^1,2*, Lisa Pieri, MD, PhD^1,2*, Emanuela Sant'Antonio, MD^2*, Carmela Mannarelli, MSc^2*, Giuseppe Loscocco^1,2*, Chiara Paoli, BS^1,2*, Lucia Merli, BSN^1,2* and Alessandro M. Vannucchi^1,2

¹Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
²CRIMM-Centro Ricerca e Innovazione delle Malattie Mieloproliferative, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy

Ayalew Tefferi, MD¹, Terra L. Lasho, PhD^1*, Christy Finke, BS^2*, Yoseph Elala, MD^3*, Daniela Barraco, MD^4*, Curtis A. Hanson, MD⁵, Rhett P. Ketterling, MD^6*, Animesh Pardanani, MBBS, PhD⁷ and Naseema Gangat, MBBS¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Hematology, Mayo Clinic, Rochester, MN
³Mayo Clinic, Rochester
⁴Mayo Clinic, Rochester, MN
⁵Division of Hematopathology, Mayo Clinic, Rochester, MN
⁶Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁷Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN