-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
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631.O1.6 631. Chronic Myeloid Leukemia: Biology and Pathophysiology, excluding Therapy: Targeting Leukemic Stem Cells in Chronic Myeloid Leukemia

Chronic Myeloid Leukemia: Biology and Pathophysiology, excluding Therapy Program: Oral and Poster Abstracts
Type: Oral
Saturday, December 5, 2015: 9:30 AM-11:00 AM
W340, Level 3 (Orange County Convention Center)
Moderators:
Mhairi Copland, University of Glasgow and Ali G Turhan Sr., M.D., PhD, INSERM U935

Disclosures:
Copland: Novartis: Honoraria , Membership on an entity’s Board of Directors or advisory committees , Speakers Bureau ; Bristol-Myers Squibb: Honoraria , Membership on an entity’s Board of Directors or advisory committees , Research Funding ; Pfizer: Honoraria , Membership on an entity’s Board of Directors or advisory committees , Speakers Bureau ; Ariad: Honoraria , Membership on an entity’s Board of Directors or advisory committees , Speakers Bureau ; Gilead: Honoraria , Speakers Bureau .
9:30 AM

Ross Kinstrie, PhD, BSc1*, Gillian A. Horne, BSc hons, MBChB, MRCP, MRES1*, Heather Morrison, BSc hons1*, Hothri A. Moka, BSc hons1*, Jennifer Cassels, BSc hons1*, Karen Dunn, BSc hons1*, Pawel Herzyk, MSc, PhD2*, David A. Irvine, BSc, MBBChir, MRCP, FRCPath, PhD3 and Mhairi Copland, BSc (Hons) MB ChB PhD FRCP FRCPath1

1Paul O'Gorman Leukaemia Research Centre, University of Glasgow, Glasgow, United Kingdom
2Glasgow Polyomics, University of Glasgow, Glasgow, United Kingdom
3Bone Marrow Transplant Unit, Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

9:45 AM

Katherine Sullivan1*, Elisabeth Bolton-Gillespie1*, Margaret Nieborowska-Skorska1*, Sabine Cerny-Reiterer, DVM2*, Peter Valent, MD3, Markus Muschen, MD PhD4, Richard Pomerantz1*, Alexander Mazin5* and Tomasz Skorski1

1Temple University School of Medicine, Philadelphia, PA
2Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria
3Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
4Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
5Drexel University, Philadelphia, PA

10:00 AM

Bin Zhang, PhD1*, Ling Li, PhD2, Ching-Cheng Chen, PhD2, Anthony S. Stein, MD3, Haris Ali, MD4*, David S. Snyder, MD3, Allen Lin5*, Adrienne Dorrance, PhD6*, Piotr Swiderski, PhD7*, Ravi Bhatia, MD8*, Danilo Perrotti, MD, PhD9*, Stephen J. Forman, MD10, Ya-Huei Kuo, PhD3, Marcin Kortylewski, PhD7* and Guido Marcucci, MD2*

1Division of Hematopoietic Stem Cell & Leukemia, City of Hope National Medical Center, Duarte, CA
2Division of Hematopoietic Stem Cell and Leukemia Research of Beckman Research Institute, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA
3Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA
4City of Hope, Duarte, CA
5Division of Hematopoietic Stem Cell and Leukemia Research of Beckman Research Institute, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA
6Ohio State University, Columbus, OH
7City of Hope National Medical Center, Duarte, CA
8University of Alabama Birmingham, Birmingham, AL
9University of Maryland, Baltimore, MD
10Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA

10:15 AM

Xiaohu Liu, MSc1,2, Clark Fruhstorfer, BSc2*, Katharina Rothe, BSc, MSc2,3 and Xiaoyan Jiang, MD PhD1,2,3

1Department of Medicine, University of British Columbia, Vancouver, BC, Canada
2Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada
3Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada

10:30 AM

Giovannino Silvestri, PhD1*, Lorenzo Stramucci, PhD1*, Justin Ellis2*, Justine Yu3*, Jason Harb, PhD4*, Paolo Neviani, PhD5, Guido Marcucci, MD6*, Klara Srutova7*, Katerina Machova Polakova8*, Denis-Claude Roy, MD9, Peter Hokland, M.D.10, Michael W. Deininger11, Ravi Bhatia, MD12*, Carlo Gambacorti-Passerini13, Dragana Milojkovic14*, Alistair G Reid, BSc, PhD15*, Jane F. Apperley, MD16, Ferenc Livak, PhD17*, Maria R. Baer, MD18, Rossana Trotta, PhD19* and Danilo Perrotti, MD, PhD20

1The Greenebaum Cancer Center, Dept. of Medicine, University of Maryland Baltimore, school of Medicine, Baltimore, MD
2The Ohio State University Comprehensive Cancer Center, Columbus, OH
3the Greenebaum Cancer Center, Dept. of Medicine, University of Maryland Baltimore, school of Medicine, Baltimore, MD
4Blood Research Institute BloodCenter of Wisconsin, Milwaukee, WI
5Norris Comprehensive Cancer Center, Children's Hospital Los Angeles, Los Angeles, CA
6Division of Hematopoietic Stem Cell and Leukemia Research of Beckman Research Institute, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA
7Institute of Hematology and Blood Transfusion, Prague, Czech Republic
8Institute of Hematology and Blood Transfusion, University of Prague, Prague, Czech Republic
9Department of Hematology and Cellular Therapy Laboratory, Hôpital Maisonneuve-Rosemont, University of Montreal, Montreal, QC, Canada
10Department of Hematology, Aarhus University Hospital, Aarhus, Denmark
11Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
12University of Alabama Birmingham, Birmingham, AL
13Azienda Ospedaliera San Gerardo/University of Milano-Bicocca, Monza, Italy
14Department of Haematology, Hammersmith Hospital (Imperial College Healthcare NHS Trust), London, United Kingdom
15Haematology Department, Hammersmith Hospital (Imperial College Healthcare NHS Trust), London, United Kingdom
16Department of Haematology, Imperial College London, Hammersmith Hospital, London, United Kingdom
17Microbiology and Immunology, University of Maryland Baltimore, school of Medicine, Baltimore, MD
18Greenebaum Cancer Center, University of Maryland Baltimore, Baltimore, MD
19Dept. microbiology and Immunology, University of Maryland Baltimore, school of Medicine, Baltimore, MD
20Dept. Medicine, University of Maryland - Greenebaum Cancer Center, Baltimore, MD

10:45 AM

Puneet Agarwal, MS1, Bin Zhang, PhD2*, Yinwei Ho, MS2*, Amy Cook, PhD2*, Ling Li, PhD2, Youzhen Wang, PhD3*, Margaret E Mclaughlin, MD3* and Ravi Bhatia, MD1

1Division of Hematology/Oncology, University of Alabama Birmingham, Birmingham, AL
2Division of Hematopoietic Stem Cell & Leukemia, City of Hope National Medical Center, Duarte, CA
3Translational Clinical Oncology, Novartis Institute of Biomedical Research, Cambridge, MA

*signifies non-member of ASH