-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

617.O3.6 617. Acute Myeloid Leukemia: Biology, Cytogenetics and Molecular Markers in Diagnosis and Prognosis: Omics-based Approaches for the Identification of Novel Genetic Modalities in AML

Acute Myeloid Leukemia: Biology, Cytogenetics and Molecular Markers in Diagnosis and Prognosis Program: Oral and Poster Abstracts
Type: Oral
Saturday, December 5, 2015: 12:00 PM-1:30 PM
Tangerine 3 (WF3-4), Level 2 (Orange County Convention Center)
Moderators:
Anupriya Agarwal, PhD, Oregon Health & Science University and Alexandre Puissant, PhD, Dana-Farber Cancer Instituté

Disclosures:
Agarwal: CTI BioPharma: Research Funding .
12:00 PM

Moritz Gerstung, PhD1,2*, Elli Papaemmanuil, PhD2,3*, Inigo Martincorena, PhD2*, Lars Bullinger, MD4, Verena I. Gaidzik, MD4*, Peter Paschka, MD4, Michael Heuser, M.D.5, Felicitas Thol, MD6, Niccolo Bolli, mD, PhD2,7*, Peter Ganly8*, Arnold Ganser, M.D.6, Ultan McDermott, MD, PhD2*, Michael R Stratton, MD, PhD2*, Konstanze Döhner, MD4, Hartmut Döhner, Prof. Dr.4, Richard F. Schlenk, MD4 and Peter J Campbell, MD, PhD9*

1European Bioinformatics Institute EMBL-EBI, Cambridge, United Kingdom
2Wellcome Trust Sanger Institute, Cambridge, United Kingdom
3Memorial Sloan Kettering Cancer Center, New York, NY
4Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
5Hematology, Hemostasis, Oncology and SCT, Hannover Medical School, Hannover, Germany
6Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
7Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, University of Milano, Milan, Italy
8Christchurch Hospital, Christchurch, New Zealand
9Cancer genome Project, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

12:15 PM

Aziz Nazha, MD1, Ahmad Zarzour, MD2, Tomas Radivoyevitch, PhD3*, Hetty E. Carraway, MD, MBA4, Jennifer S. Carew, Ph.D.5, Cassandra M Hirsch6*, Kassy E Kneen7*, Bartlomiej Przychodzen, MSc8*, Bhumika J. Patel5*, Michael Clemente, MS9*, Srinivasa R. Sanikommu, MBBS10, Matt Kalaycio, MD11, Jaroslaw P. Maciejewski, MD, Ph.D.5 and Mikkael A. Sekeres, MD, MS4

1Leukemia Program, Department of Hematology and Oncology, Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
2Leukemia Program, Cleveland Clinic - Taussig Cancer Institute, Cleveland, OH
3Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH
4Leukemia Program, Cleveland Clinic, Cleveland, OH
5Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
6Department of Translational Hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, Cleveland, OH
7Department of Translational Hematology, Cleveland Clinic, Taussig Cancer Institute, Cleveland
8Haematological Medicine, Department of Translational hematology and Oncology Research, Taussing Cancer Institute, Cleveland Clinic, London, United Kingdom
9Experimental Hematology and Hematopoiesis, Cleveland Clinic Foundation, Cleveland, OH
10Cleveland Clinic Taussing Cancer Institute, Cleveland, OH
11Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

12:30 PM

Katherine Tarlock, MD1, M. Eva Hansen2*, Tiffany Hylkema2*, Rhonda Ries, MA3*, Jason E. Farrar, M.D.4, Jaime Guidry Auvil5*, Daniela S. Gerhard, PhD6*, Malcolm A. Smith, MD, PhD7*, Tanja M. Davidsen, PhD6*, Patee Gesuwan6*, Leandro C. Hermida6*, Marco A Marra, PhD8, Andrew J. Mungall, PhD9, Karen Mungall, PhD9*, Yussanne Ma9*, Stuart Zong9*, William Long, PhD9*, Titus Boggon, PhD10*, Todd A. Alonzo, PhD11, E. Anders Kolb, MD12, Alan S. Gamis, MD, MPH13 and Soheil Meshinchi, MD, PhD3

1Fred Hutchinson Cancer Research Center, Seattle, WA
2Fred Hutchsinson Cancer Research Center, Seattle, WA
3Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
4Department of Pediatics/Hematology Oncology Section, University of Arkansas for Medical Sciences, Little Rock, AR
5National Cancer Institute, Bethesda
6Office of Cancer Genomics, National Cancer Institute, Bethesda, MD
7NCI/Ctep/Cib, National Institutes of Health, Bethesda, MD
8Canada’s Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
9Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
10Pharmacology, Yale Univ. School of Medicine, New Haven, CT
11Keck School of Medicine, University of Southern California, Los Angeles, CA
12Nemours Center for Cancer and Blood Disorders, Alfred I. duPont Hospital for Children, Wilmington, DE
13Division of Hematology/Oncology/Bone Marrow Transplantation, Children's Mercy Hospitals and Clinics, Kansas City, MO

12:45 PM

Fiona Brown, PhD1*, Eric Still1*, Paolo Cifani, PhD1*, Scott Ficarro, PhD2*, Gayle Pouliot, MD, PhD3, Esther Drill, PhD1*, Mithat Gonen, PhD4*, Jie He, PhD5*, Sohail Balasubramanian, M.S.5*, Shan Zhong, PhD5*, Dean Pavlick5*, Bahar Yilmazel5*, Andrei V. Krivtsov, PhD6*, Todd A. Alonzo, PhD7, Soheil Meshinchi, MD, PhD8, Steven M. Kornblau, MD9, Richard M. Stone, MD10, Guido Marcucci, MD11, John C. Byrd, MD12, Ross L. Levine, MD13, Scott A. Armstrong, MD, PhD1, Nathanael Gray, PhD14*, Jarrod Marto, PhD2* and Alex Kentsis, MD, PhD13

1Memorial Sloan-Kettering Cancer Center, New York, NY
2Dana-Farber Cancer Institute, Boston, MA
3Children's Hospital Boston, Boston, MA
4Statistics, Memorial Sloan Kettering Cancer Center, New York, NY
5Foundation Medicine, Inc., Cambridge, MA
6Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
7Children's Oncology Group, Monrovia, CA
8Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
9Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
10Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
11The Ohio State University Comprehensive Cancer Center, Columbus, OH
12Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
13Memorial Sloan Kettering Cancer Center, New York, NY
14Dept of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA

1:00 PM

Satoshi Saida, MD, PhD1,2*, Masahiro Nakamura, MD, PhD3*, Tsutomu Toki, PhD4, Yoko Nishinaka-Arai, Ph.D.5*, Kiminori Terui, MD, PhD4*, Kenichi Yoshida, MD, Ph.D.6*, Seishi Ogawa, MD, Ph.D.6, Tatsutoshi Nakahata, MD, PhD2,5, Toshio Heike, MD, PhD1,2*, Ken-ichiro Watanabe, MD, PhD1,2,7*, Akira Watanabe, PhD2,3* and Etsuro Ito, MD, PhD2,4

1Department of Pediatrics, Graduate School of Medicine Kyoto University, Kyoto, Japan
2AMED-CREST, Japan Agency for Medical Research and Development, 1-7-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Tokyo, Japan
3Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan
4Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan
5Clinical Application Department, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan
6Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
7Division of Hematology and Oncology, Shizuoka Children's Hospital, Shizuoka, Japan

1:15 PM

Francois Vergez, DVM, PhD1,2*, Sarah Bertoli, MD, PhD3*, Marina Bousquet, PhD3*, Marie-Laure Nicolau-Travers4*, Michael Peres, PharmD2*, Estelle Saland5*, Françoise Huguet, MD6*, Isabelle Luquet, MD7*, Veronique Mansat-de Mas, PharmD, PhD2*, Cecile Demur, MD8*, Eric Delabesse, MD, PhD2*, Gwenn Danet-Desnoyers, PhD1, Jean-Emmanuel Sarry, PhD5* and Christian Récher, MD PhD9

1Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Institut Universitaire du Cancer, University Hospital of Toulouse, Toulouse, France
3INSERM, Cancer Research Center of Toulouse, Toulouse, France
4Institut Universitaire du Cancer, Toulouse, France
5INSERM, CRCT, Toulouse, France
6Hematology department, Institut universitaire du cancer de Toulouse, Toulouse, France
7CHU Toulouse, Toulouse, France
8Hopital PURPAN, Toulouse, France
9Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France

*signifies non-member of ASH