Liran I. Shlush, MD PhD¹, Amanda Mitchell, Ph.D.^2*, Lawrence Heisler, Ph.D.^3*, Sagi Abelson, Ph.D.^2*, Monica Doedens^1*, McLeod Jessica, Ms.C.^2*, John D. McPherson, PhD^4*, Thomas Hudson, M.D. Ph.D.^3*, Jean C.Y. Wang, MD PhD⁵, Mark D. Minden, MD, PhD¹ and John E. Dick, PhD¹

¹Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada
³Ontario Institute for Cancer Research, Toronto, ON, Canada
⁴Genome Technologies, Ontario Institute for Cancer Research, Toronto, ON, Canada
⁵Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

Felicitas Thol, MD¹, Larissa Köhler^1*, Sabrina Klesse^1*, Razif Gabdoulline^1*, Arnold Kloos, PhD^1*, Alessandro Liebich^1*, Martin Wichmann^2*, Anuhar Chaturvedi, PhD, MS, BPharm^3*, Jana Fabisch^1*, Verena I. Gaidzik, MD^4*, Peter Paschka, MD⁴, Lars Bullinger, MD⁴, Gesine Bug, MD^5*, Hubert Serve, MD^6*, Gudrun Göhring, MD^7*, Brigitte Schlegelberger, MD, PhD⁷, Michael Luebbert, MD^8*, Hartmut H. Kirchner, MD^9*, Mohammad Amen Wattad, MD¹⁰, Doris Kraemer, MD^11*, Bernd Hertenstein, MD^12*, Gerhard Heil, MD^13*, Walter Fiedler, MD¹⁴, Juergen Krauter, MD^15*, Richard F. Schlenk, MD¹⁶, Konstanze Döhner, MD⁴, Hartmut Döhner, MD^4*, Arnold Ganser, M.D.¹ and Michael Heuser, M.D.³

¹Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
²Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannoverg, Germany
³Hematology, Hemostasis, Oncology and SCT, Hannover Medical School, Hannover, Germany
⁴Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
⁵Department of Medicine, Hematology/Oncology, University of Frankfurt, Frankfurt, Germany
⁶Dept. of Internal Medicine, University Hospital of Frankfurt, Frankfurt, Germany
⁷Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
⁸Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany
⁹Klinikum Hannover Siloah, Hannover, Germany
¹⁰Kliniken Essen Sued, Essen, Germany
¹¹Department of Oncology and Hematology, Klinikum Oldenburg, Oldenburg, Germany
¹²Klinikum Bremen Mitte, Bremen, Germany
¹³Department of Internal Medicine V, Klinikum Lüdenscheid, Lüdenscheid, Germany
¹⁴Department of Hematology and Oncology with sections Pneumonology and Bone Marrow Transplantation, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
¹⁵Department of Hematology and Oncology, Klinikum Braunschweig, Braunschweig, Germany
¹⁶University Hospital of Ulm, Ulm, Germany

Brian Parkin¹, Angelina Londoño Joshi, PhD^2*, Qing Kang, PhD^1*, Andrew D. Rhim, MD^2* and Sami N. Malek¹

¹Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI
²Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI

Verena I. Gaidzik, MD^1*, Daniela Weber^1*, Peter Paschka, MD¹, Anna Kaumanns^1*, Stefan Krieger^1*, Andrea Corbacioglu, PhD^1*, Jan Kroenke, MD^1*, Silke Kapp-Schwoerer, MD^1*, Doris Krämer, MD^2*, Heinz A. Horst, MD, PhD³, Ingo Schmidt-Wolf, MD⁴, Gerhard Held, MD^5*, Andrea Kuendgen, MD^6*, Mark Ringhoffer, MD^7*, Katharina Goetze, MD^8*, Thomas Kindler, MD^9*, Walter Fiedler, MD¹⁰, Mohammad Amen Wattad, MD¹¹, Lars Bullinger, MD¹², Brigitte Schlegelberger, MD, PhD¹³, Felicitas Thol, MD¹⁴, Michael Heuser, MD¹⁴, Arnold Ganser, M.D.¹⁴, Richard F. Schlenk, MD¹, Hartmut Döhner, MD^1* and Konstanze Döhner, MD¹

¹Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
²Department of Oncology and Hematology, University of Oldenburg, Oldenburg, Germany
³Department of Internal Medicine II, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany
⁴Center for Integrated Oncology (CIO) and Medizinische Klinik und Poliklinik III, University of Bonn, Bonn, Germany
⁵Internal Medicine I, Saarland University Medical School, Homburg, Germany
⁶Department of Hematology, Oncology, and Clinical Immunology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany
⁷Department of Internal Medicine III, Municipal Hospital of Karlsruhe, Karlsruhe, Germany
⁸Technische Universität München, München, Germany
⁹University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
¹⁰Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
¹¹Kliniken Essen Sued, Essen, Germany
¹²Department of Internal Medicine III, University of Ulm, Ulm, Germany
¹³Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
¹⁴Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

Silke Kapp-Schwoerer, MD^1*, Andrea Corbacioglu, PhD^1*, Verena I. Gaidzik, MD^1*, Peter Paschka, MD¹, Daniela Weber^1*, Jan Kroenke, MD^1*, Maria-Veronica Teleanu, MD^1*, Gudrun Göhring, MD^2*, Brigitte Schlegelberger, MD, PhD², Michael Luebbert, MD^3*, Thomas Kindler, MD^4*, Mohammad Amen Wattad, MD⁵, Andrea Kuendgen, MD^6*, David Nachbaur, MD^7*, Walter Fielder, MD^8*, Helmut Rainer Salih⁹, Heinz A. Horst, MD, PhD¹⁰, Karin Tina Mayer, MD^11*, Katharina S. Götze, MD¹², Martin Bentz, MD¹³, Jan Schleicher, MD^14*, Felicitas Thol, MD¹⁵, Michael Heuser, MD¹⁵, Jürgen Krauter, MD^16*, Arnold Ganser, M.D.¹⁵, Richard F. Schlenk, MD¹, Hartmut Döhner, MD^1* and Konstanze Döhner, MD¹

¹Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
²Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany
³Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany
⁴University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
⁵Department of Hematology, Oncology and Stem Cell Transplantation, Kliniken Essen Sued, Essen, Germany
⁶Department of Hematology, Oncology, and Clinical Immunology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany
⁷Department of Internal Medicine V, University Hospital Innsbruck, Innsbruck, Austria
⁸Hubertus Wald University Cancer Center, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany
⁹Department of Internal Medicine II, University Hospital of Tübingen, Tübingen, Germany
¹⁰Department of Internal Medicine II, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany
¹¹Department of Internal Medicine III, University Hospital Bonn, Bonn, Germany
¹²III. Department of Medicine, Hematology and Medical Oncology, Technical University of Munich, Munich, Germany
¹³Department of Internal Medicine III, Municipal Hospital of Karlsruhe, Karlsruhe, Germany
¹⁴Department of Hematology and Oncology, Katharinenhospital Stuttgart, Stuttgart, Germany
¹⁵Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
¹⁶Department of Internal Medicine III, Municipal Hospital of Braunschweig, Braunschweig, Germany

Torsten Haferlach, Manja Meggendorfer, PhD^*, Susanne Schnittger, PhD, Annette Fasan, PhD^*, Wolfgang Kern, MD and Claudia Haferlach, MD

MLL Munich Leukemia Laboratory, Munich, Germany