-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

614.O2.6 614. Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation: Advances in Treatment and Preclinical Studies

Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation Program: Oral and Poster Abstracts
Type: Oral
Monday, December 7, 2015: 4:30 PM-6:00 PM
W224CDGH, Level 2 (Orange County Convention Center)
Moderators:
Josep-Maria Ribera, MD, PhD, ICO Badalona-Hospital Germans Trias i Pujol. Josep Carreras Leukemia Research Institute. Universitat Autònoma de Barcelona and Oliver G Ottmann, MD, Cardiff University

Disclosures:
No relevant conflicts of interest to declare.
4:30 PM

Caroline Piette1*, Stefan Suciu2, Emmanuelle Clappier3*, Yves Bertrand, MD, PhD4*, Genevieve Plat, MD5*, Christophe Chantrain6*, Vitor Costa7*, Nicole Dastugue8*, Alina Ferster9, Caroline Gilotay2*, Sandrine Girard10*, Nathalie Grardel11*, Patrick Lutz12*, Francoise Mazingue, MD13, Odile Minckes14*, Martine Munzer15*, Emmanuel Plouvier, MD16*, Nicolas Sirvent17*, Anne Uyttebroeck18*, Nadine van Roy, MD19*, Karima Yakouben, MD20*, Yves Benoit21 and Hélène Cavé3*

1University Department of Pediatric Oncology, CHR Citadelle, Liège, Belgium
2EORTC Headquarters, Brussels, Belgium
3Hôpital Robert Debré, AP-HP, Paris, France
4Pediatric hematology, CHU Lyon, Lyon, France
5pediatric hematology, CHU Toulouse, Toulouse, France
6Clinique de l'Espérance, Liège, Belgium
7Instituto Portugues de Oncologia - Centro do Porto, Porto, Portugal
8CHU Toulouse, Toulouse, France
9HUDERF, Brussels, Belgium
10CHU Lyon, Lyon, France
11CHRU Lille, Lille, France
12CHRU Strasbourg, Strasbourg, France
13hematology, CHRU Lille, Lille, France
14CHU Caen, Caen, France
15CHU Reims, Reims, France
16pediatric hematology, CHRU Besançon, Besançon, France
17Hôpital Arnaud de Villeneuve, Montpellier, France
18University Hospital Leuven, Leuven, Belgium
19Center for Medical Genetics, Ghent University, Ghent, Belgium
20Robert Debre Hospital, AP-HP, Paris, France
21University Hospital Ghent, Ghent, Belgium

4:45 PM

Stuart S. Winter, MD1, Meenakshi Devidas, PhD2, Si Chen, MS2*, Barbara Asselin, MD3, William L. Carroll, MD4, Brent L Wood, MD, PhD5, Natia Esiashvili, MD6*, Briegel J Nikki, PharmD7*, Robert J. Hayashi, MD8*, Mignon L. Loh, MD9, Andrew J. Carroll, PhD10, Nyla A. Heerema, PhD11, Elizabeth Raetz, MD12, Naomi J. Winick, MD13, Stephen P. Hunger, MD14,15 and Kimberly P. Dunsmore, MD16

1Department of Pediatrics, University of New Mexico, Albuquerque, NM
2Department of Biostatistics, Colleges of Medicine, Public Health & Health Profession, University of Florida, Gainesville, FL
3Pediatric Hematology-Oncology, University of Rochester, Rochester, NY
4Department of Pediatrics, Perlmutter Cancer Center,, New York University Medical Center, New York, NY
5Seattle Cancer Care Alliance, Seattle, WA
6Radiation Oncology, Children's Healthcare of Atlanta - Egleston, Atlanta, GA
7Dept of Pharmacy, Princess Margaret Hospital for Children, Perth, Australia
8Pediatric Hematology/Oncology, Washington University School of Medicine, St. Louis, MO
9Department of Pediatrics, Benioff Children’s Hospital, University of California at San Francisco, San Francisco, CA
10Department of Genetics, University of Alabama at Birmingham, Birmingham, AL
11Pathology, The Ohio State University, Columbus, OH
12Primary Children's Hospital, Salt Lake City, UT
13University of Texas Southwestern Medical Center, Dallas, TX
14Children's Hospital Philadelphia, Philadelphia, PA
15Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
16Health Sciences Center, University of Virginia, Charlottesville, VA

5:00 PM

Chezi Ganzel1*, Wang Xin Victoria2*, Adele K. Fielding, MB, BS, PhD3, Jacob M. Rowe, MD1,4, Susan M Richards, Ph.D5*, Georgina Buck6*, Rajesh Chopra, PhD7, I. Jill Durrant6*, David Marks, MD, PhD8, Ian M. Franklin, MD9, Andrew K McMilan10*, Mark R Litzow, MD11, Elisabeth Paietta, PhD12, Selina Luger, MD13, Peter H Wiernik14,15*, Dan Douer, MD16, Hillard M. Lazarus, MD17, Martin S Tallman, MD18 and Anthony H. Goldstone, FRCP, FRCPath19

1Hematology, Shaare Zedek Medical Center, Jerusalem, Israel
2Dana Farber Cancer Institute, Boston, MA
3Cancer Institute, Royal Free and University College Medical School, London, United Kingdom
4Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel
5Clinical Trial Service Unit, Old Road Campus, Oxford, United Kingdom
6Clinical Trial Service Unit, Oxford, England
7Christie Hosptital National Health Service (NHS) Trust, Manchester, United Kingdom
8Bristol Children's Hospital, Bristol, England
9Snbts, University of Glasgow, Glasgow, England
10Nottingham University Hospitals, Nottingham, England
11Division of Hematology, Mayo Clinic, Rochester, MN
12Cancer Center, Montefiore Medical Center North Division, Bronx, NY
13Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
14Albert Einstein College of Medicine, Bronx
15Beth Israel Medical Center, New York
16Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
17University Hospitals Case Medical Center, Cleveland, OH
18Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
19Univ. College London Hosp., London, England

5:15 PM

Farhad Ravandi, MD1, Megan Othus, PhD2*, Susan O'Brien, MD3, Stephen J. Forman, MD4, Chul S. Ha, MD5, Jeffrey Y. C. Wong, MD4*, Martin S Tallman, MD6*, Elisabeth Paietta, PhD7, Janis Racevskis, PhD8*, Geoffrey L. Uy, MD9, Uma Borate, MD10, Partow Kebriaei, MD11, Laura Kingsbury, MRT2*, Hagop M. Kantarjian, MD1, Jerald P. Radich12, Harry P. Erba, MD, PhD13* and Frederick R. Appelbaum, MD14

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2SWOG Statistical Center, Seattle, WA
3University of California - Irvine, Orange, CA
4City of Hope National Medical Center, Duarte, CA
5University of Texas Health Science Center, San Antonio, TX
6Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
7Cancer Center, The North Division of Montefiore Medical Center, Bronx, NY
8Albert Einstein College of Medicine, Montefiore Medical Center, New York, NY
9Division of Oncology, Washington University School of Medicine, St. Louis, MO
10University of Alabama at Birmingham, Birmingham, AL
11Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
12Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
13University of Alabama at Birmingham and UAB Comprehensive Cancer Center, Birmingham, AL
14Fred Hutchinson Cancer Research Center, Seattle, WA

5:30 PM

Elizabeth C Townsend, PhD1*, Tiffany DeSouza, B.S.2*, Mark A. Murakami, MD, MA2, Joan Montero, Ph.D.1*, Kristen Stevenson, MS3*, Amanda L Christie, B.S.2*, Alexandra N Christodolou, M.Sc.1*, Una Vojinovic, B.S.1*, Nadja Kopp, M.S.4*, Patrizia Barzaghi-Rinaudo5*, Masato Murakami, M.D., Ph.D5*, Anthony Letai, MD, PhD2, Sebastien Jeay6*, Jens Wuerthner6*, Ensar Halilovic7* and David M. Weinstock4

1Dana Farber Cancer Institute, Boston, MA
2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
3Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
4Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
5Novartis Institute for Biomedical Research, Basel, Switzerland
6Novartis Pharma AG, Basel, Switzerland
7Novartis Institutes for BioMedical Research, Cambridge, MA

5:45 PM

Sarah K Tasian, MD1,2, Yong Li, MD MS3*, Feng Shen, MD PhD3*, Theresa Ryan3*, Tiffaney L Vincent3*, David T Teachey, MD1,4, Shannon L Maude, MD, PhD1,4, Richard C Harvey, PhD5, I-Ming L Chen, DVM, MS5, Cheryl L Willman6, Alexander E. Perl, MD7,8, Stephen P Hunger, MD2,9, Mignon L. Loh, MD10, Martin Carroll, MD8,11 and Stephan A. Grupp, MD, PhD4,12

1Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
2Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA
3Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
4Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
5Pathology, University of New Mexico Cancer Center, Albuquerque, NM
6University of New Mexico Cancer Center, Albuquerque, NM
7University of Pennsylvania-Abramson Comprehensive Cancer Center, Philadelphia, PA
8Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA
9Department of Pediatrics, Children’s Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
10Department of Pediatrics, Benioff Children’s Hospital, University of California at San Francisco, San Francisco, CA
11Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
12Division of Oncology and Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, Philadelphia, PA

*signifies non-member of ASH