-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

613.O3.6 613. Acute Myeloid Leukemia: Clinical Studies: Advances in Targeted Therapy

Acute Myeloid Leukemia: Clinical Studies Program: Oral and Poster Abstracts
Type: Oral
Sunday, December 6, 2015: 4:30 PM-6:00 PM
W110, Level 1 (Orange County Convention Center)
Moderators:
Terzah M. Horton, MD, PhD, Baylor College of Medicine and Claude Gardin, MD, Avicenne Hospital, APHP, University Paris 13

Disclosures:
No relevant conflicts of interest to declare.
4:30 PM

Geoffrey L. Uy, MD1, Sumithra Mandrekar, PhD2*, Kristina Laumann2*, Ben Sanford3*, Guido Marcucci, MD4, Weiqiang Zhao, MD, PhD5, Mark J. Levis, MD, PhD6, Heidi D. Klepin, MD, MS7, Maria R. Baer, MD8, Bayard L. Powell, MD7, Peter Westervelt, MD, PhD1, Daniel J. DeAngelo, MD, PhD9, Wendy Stock, MD10, Clara D. Bloomfield, MD11, John C. Byrd, MD11, Richard M. Stone, MD12 and Richard A. Larson, MD10

1Division of Oncology, Washington University School of Medicine, St. Louis, MO
2Mayo Clinic, Rochester, MN
3Duke University, Durham, NC
4City of Hope, Duarte, CA
5Pathology, The Ohio State University, Columbus, OH
6Johns Hopkins University School of Medicine, Baltimore, MD
7Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, NC
8Greenebaum Cancer Center, University of Maryland Baltimore, Baltimore, MD
9Dana-Farber Cancer Institute, Boston, MA
10The University of Chicago, Chicago, IL
11The Ohio State University Comprehensive Cancer Center, Columbus, OH
12Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

4:45 PM

Khan Naeem, PhD1*, Robert K. Hills, MA, MSc, DPhil2, Paul Virgo, BSc,3*, Stephen Couzens4*, Nithiya Clark1*, Amanda Gilkes5*, Angela Grech2*, Peter Richardson1*, Steven Knapper6, David Grimwade, PhD, FRCPath7, Nigel H. Russell, MD8, Alan K. Burnett, MD FRCP5 and Sylvie Freeman, PhD FRCPath1*

1Immunity and Infection, University of Birmingham, Birmingham, United Kingdom
2School of Medicine, Department of Haematology and Institute of Translation Innovation Methodology & Engagement, Cardiff University, Cardiff, United Kingdom
3North Bristol NHS Trust, Bristol, United Kingdom
4University Hospital of Wales, Cardiff, United Kingdom
5Institute of Cancer & Genetics, Cardiff University, Cardiff, United Kingdom
6Cardiff University, Cardiff, United Kingdom
7Dept of Medical & Molecular Genetics, King's College London School of Medicine, London, United Kingdom
8Centre for Clinical Haematology, Nottingham University Hospital, Nottingham, United Kingdom

5:00 PM

Jessica K. Altman, MD1, Alexander E. Perl, MD2, Jorge E. Cortes, MD3, Mark J. Levis, MD, PhD4, Catherine C. Smith, MD5, Mark R Litzow, MD6, Maria R. Baer7, David F. Claxton, MD8*, Harry P. Erba, MD, PhD9*, Stanley C. Gill, PhD10*, Stuart L. Goldberg11, Joseph G. Jurcic, MD12, Richard A. Larson, MD13, Charles Lui, PhD10*, Ellen K Ritchie, MD14, Briana Sargent, BS10*, Gary J Schiller, MD15, Alexander I. Spira, MD, PhD16, Stephen A. Strickland, MD17, Raoul Tibes, MD, PhD18, Celalettin Ustun, MD19, Eunice S. Wang, MD20, Robert K. Stuart, MD21, Claudia D. Baldus, MD, PhD22*, Christoph Rollig23*, Andreas Neubauer, MD24, Giovanni Martinelli25 and Erkut Bahceci, MD10

1Northwestern University, Chicago, IL
2University of Pennsylvania-Abramson Comprehensive Cancer Center, Philadelphia, PA
3MD Anderson Cancer Center, Houston, TX
4Johns Hopkins University, Baltimore, MD
5Department of Medicine, University of California at San Francisco, San Francisco, CA
6Division of Hematology, Mayo Clinic, Rochester, MN
7University of Maryland Greenebaum Cancer Center, Baltimore, MD
8Penn State Milton S. Hershey Medical Center, Hershey, PA
9University of Alabama at Birmingham and UAB Comprehensive Cancer Center, Birmingham, AL
10Astellas Pharma US, Inc., Northbrook, IL
11Hackensack University Medical Center, Hackensack, NJ
12Columbia University Medical Center, New York, NY
13University of Chicago, Chicago, IL
14Weill Cornell Medical Center, New York, NY
15University of California Los Angeles Medical Center, Los Angeles, CA
16Virginia Cancer Specialists, Fairfax, VA
17Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN
18Mayo Clinic Scottsdale Arizona, Scottsdale, AZ
19Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
20Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY
21Medical University of South Carolina, Charleston, SC
22Charité University Hospital, Berlin, Germany
23Universitätsklinikum TU, Dresden, Germany
24Universitätsklinikum Giessen und Marburg, Marburg, Germany
25“Seragnoli” Institute of Hematology, Bologna, Italy

5:15 PM

Richard Schlenk, M.D.1, Konstanze Döhner, MD2, Helmut Salih, MD3, Andrea Kündgen4*, Walter Fiedler, MD5, Hans-Juergen Salwender, MD6*, Joerg Westermann, MD7*, Katharina S. Götze, MD8, Heinz-August Horst, MD, PhD9, Gerald Wulf, MD10, Michael Lübbert, MD11*, Doris Kraemer, MD12*, Thomas Kindler, MD13*, Mark Ringhoffer, MD14*, Peter Brossart, MD15, Gerhard Held, MD16*, Richard Greil17, Thomas Südhoff, M.D.18*, Anja Münnich1*, Daniela Weber2*, Verena I. Gaidzik, MD2*, Maria-Veronica Teleanu, MD2*, Peter Paschka, MD2, Frauke Theis2*, Michael Heuser, MD19, Felicitas Thol, MD19, Axel Benner20*, Arnold Ganser21 and Hartmut Döhner, Prof. Dr.2

1Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany
2Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
3University Hospital Tübingen, Tübingen, Germany
4Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
5Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
6Asklepios Hospital Hamburg Altona, Hamburg, Germany
7Department of Hematology, Oncology and Tumor Immunology, Charité-University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany
8III. Department of Medicine, Hematology and Medical Oncology, Technical University of Munich, Munich, Germany
9Medizinische Klinik und Poliklinik im Städtischen Krankenhaus, Kiel, Germany
10Department of Hematology and Oncology, University Hospital of Goettingen, Goettingen, Germany
11Department of Internal Medicine I, University Freiburg - Medical Center, Freiburg, Germany
12Department of Oncology and Hematology, Klinikum Oldenburg, Oldenburg, Germany
13University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
14Department of Internal Medicine III, Municipal Hospital of Karlsruhe, Karlsruhe, Germany
15Internal Medicine III, Oncology, Hematology and Rheumatology, University Clinic Bonn, Bonn, Germany
16Internal Medicine I, Saarland University Medical School, Homburg, Germany
17University of Salzburg, salzburg, Austria
18Klinikum Passau, Passau, Germany
19Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
20German Cancer Research Center, Heidelberg, Germany
21Dept. Hem/Onc & Transplantation, Hannover Medical School, Hannover, Germany

5:30 PM

Eytan M. Stein, MD1, Courtney DiNardo, MD2, Jessica K. Altman, MD3, Robert Collins, MD4, Daniel J. DeAngelo, MD, PhD5, Hagop M. Kantarjian, MD6, Mikkael A. Sekeres, MD, MS7, Amir T. Fathi, MD8, Ian W. Flinn, MD, PhD9, Arthur E. Frankel, MD4, Ross L. Levine, MD1, Bruno C. Medeiros, MD10, Manish R. Patel, MD11, Daniel Pollyea, MD, MS12, Gail J. Roboz, MD13, Richard M. Stone, MD5, Ronan T. Swords, MD, PhD, FRCPI, FRCPath14, Martin S. Tallman, MD1, Katherine Yen, PhD15*, Eyal C. Attar, MD15, Qiang Xu, PhD16*, Alessandra Tosolini, BS16*, Jay M. Mei, MD, PhD16, Anjan Thakurta16*, Robert D. Knight, MD16 and Stéphane De Botton, MD, PhD17*

1Memorial Sloan Kettering Cancer Center, New York, NY
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
4University of Texas Southwestern Medical Center, Dallas, TX
5Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
6MD Anderson Cancer Center, Houston, TX
7Leukemia Program, Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
8Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA
9Sarah Cannon Research Institute, Nashville, TN
10Division of Hematology/Oncology, Stanford Comprehensive Cancer Center, Stanford Univ., Stanford, CA
11Florida Cancer Specialists/Sarah Cannon Research Institute, Sarasota, FL
12Division of Hematology, University of Colorado School of Medicine, Aurora, CO
13Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY
14Hematology/Oncology, Sylvester Comprehensive Cancer Center, University of Miami Hospitals, Miami, FL
15Agios Pharmaceuticals, Cambridge, MA
16Celgene Corporation, Summit, NJ
17Clinical Hematology, Gustave Roussy, Villejuif, France

5:45 PM

Anthony S. Stein, MD1, Roland B. Walter, MD, PhD, MS2, Harry P. Erba, MD, PhD3, Amir T. Fathi, MD4, Anjali S. Advani, MD5, Jeffrey E Lancet, M.D.6, Farhad Ravandi, MD7, Tibor J. Kovacsovics, MD8, Daniel J. DeAngelo, MD, PhD9, Dale Bixby, MD, PhD10, Stefan Faderl, MD11*, Anand P Jillella, MD12, Megan M. O'Meara, MD13, Baiteng Zhao, PhD14* and Eytan M Stein, M.D.15

1Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA
2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
3Internal Medicine, Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL
4Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA
5Leukemia Program, Cleveland Clinic, Cleveland, OH
6Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL
7Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
8Huntsman Cancer Institute - University of Utah, Salt Lake City, UT
9Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
10Univ. of Michigan Comprehensive Cancer Ctr., Ann Arbor, MI
11John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
12Winship Cancer Institute of Emory University, Atlanta, GA
13Clinical Development, Seattle Genetics, Inc., Bothell, WA
14Seattle Genetics, Inc., Bothell, WA
15Memorial Sloan Kettering Cancer Center, New York, NY

*signifies non-member of ASH