-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

508.O2.6 508. Bone Marrow Failure: A New Hope – Disease Mechanisms and Translation

Bone Marrow Failure Program: Oral and Poster Abstracts
Type: Oral
Monday, December 7, 2015: 2:45 PM-4:15 PM
Tangerine 3 (WF3-4), Level 2 (Orange County Convention Center)
Moderators:
Charles J. Parker, MD, University of Utah School of Medicine and Steven R Ellis, PhD, University of Louisville

Disclosures:
No relevant conflicts of interest to declare.
2:45 PM

Shreyans Gandhi, MBBS, MD, DNB, MRCP, FRCPath1,2*, Jie Jiang, PhD3*, Nana Benson-Quarm, B.Sc, Dip (Nursing)4*, Hanna Renshaw, MBBS, MA4*, Syed A Mian, BSc, M.Phil5*, Austin G. Kulasekararaj, MBBS, MD, MRCP, FRCPath4*, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath2,4 and Judith C. W. Marsh, MD, FRCP, FRCPath6

1Department of Hematological Medicine, Kings College Hospital NHS Foundation Trust, London, United Kingdom
2Division of Cancer Studies, Kings College London, London, United Kingdom
3Division of Cancer Studies, King's College London, London, United Kingdom
4Department of Haematological Medicine, Kings College Hospital NHS Foundation Trust, London, United Kingdom
5Department of Haematological Medicine, King's College London, London, United Kingdom
6Haematological Medicine, King's College Hospital, London, United Kingdom

3:00 PM

Adam P Deveau, BScH, MSc1*, Andrew J Coombs, BScH1*, Santhosh Dhanraj, BSc, MSc2,3*, Gretchen Wagner, BScH4*, Yigal Dror, MD, FRCP(C)2,5,6 and Jason N. Berman, MD7

1Department of Pediatrics, IWK Health Centre, Halifax, NS, Canada
2Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, ON, Canada
3Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada
4Dalhousie University, Halifax, NS, Canada
5Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
6Institute of Medical Science, University of Toronto, Toronto, ON, Canada
7Pediatrics/Microbiology and Immunology, IWK Health Centre/Dalhousie University, Halifax, NS, Canada

3:15 PM

Diane H. Moon, PHD1,2,3*, Matthew Segal1,2,3*, Baris Boyraz1,2,3,4*, Eva Guinan, MD5, Inga Hofmann, MD1,2, Patrick Cahan, PHD1*, Albert K Tai, PHD6* and Suneet Agarwal, MD, PHD1,2,3

1Hematology/Oncology, Boston Children's Hospital, Boston, MA
2Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA
3Harvard Stem Cell Institute, Boston, MA
4Basic Oncology, Hacettepe University Cancer Institute, Ankara, Turkey
5Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA
6Integrative Physiology and Pathobiology, Tufts University School of Medicine, Boston, MA

3:30 PM

Zhantao Yang, MD1*, Sioban B. Keel, MD1, Brent L. Wood, MD PhD2*, Bart L. Scott, MD, MS3 and Janis L. Abkowitz, MD1

1Medicine/Hematology, University of Washington, Seattle, WA
2Laboratory Medicine, University of Washington, Seattle, WA
3Medical Oncology, Fred Hutchinson Cancer Research Center & University of Washington, Seattle, WA

3:45 PM

Marc Gastou1,2,3*, Sarah Rio2,3,4*, Mickael Dussiot5,6,7*, Narjesse Karboul2,3,8*, Thierry Leblanc9*, Margaux Sevin10,11*, Olivier Bluteau1,12*, Narla Mohandas, D.Sc.13, William Vainchenker, MD, PhD3,12,14, Carmen Garrido, PhD3,15,16*, Eric Solary, MD, Prof17,18,19*, Olivier Hermine3,20,21,22* and Lydie Da Costa, MD, PhD2,3,4,23

1Institut Gustave Roussy, Inserm U1170, Villejuif, France
2Université Paris 7 Denis Diderot-Sorbonne Paris Cité, Paris, France
3LABEX GR-Ex, Paris, France
4Inserm U1149, CRI, Faculté de Médecine Xavier Bichat, Paris, France
5LABEX GR-Ex, France, France
6UMR 1163, Institut Imagine, Paris, France
7Université Paris Descartes, Paris, France
8Faculté de Médecine Xavier Bichat, Inserm U1149, CRI, Paris, France
9AP-HP, hôpital Robert Debré, service d’onco-hématologie pédiatrique, Paris, France
10LABEX GR-Ex, ¨Paris, France
11Inserm U866, Université de Bourgogne, Dijon, France
12Université Paris 11, Orsay, France
13Red Cell Physiology Laboratory, New York Blood Center, New York, NY
14INSERM U1170, Institut Gustave Roussy, Villejuif, France
15INSERM, unité mixte de recherche 866, Equipe labellisée Ligue contre le Cancer and Association pour la Recherche contre le Cancer, and Laboratoire d’Excellence Lipoprotéines et santé (LipSTIC), 21033 Dijon, France, Dijon, France
16University of Burgundy, Faculty of Medicine and Pharmacy, 7 boulevard Jeanne d’Arc, 21033 Dijon, France, Dijon, France
17Gustave Roussy, Villejuif, France
18INSERM U1170, VILLEJUIF, France
19Faculty of Medicine, Université Paris-Sud, Le Kremlin-Bicetre, France
20Imagine Institute, Sorbonne Paris Cité, Paris Descartes University, Paris, France
21Institut Imagine, INSERM 1163/CNRS ERL 8254, Paris, France
22Department of Hematology, Necker Children's hospital, APHP, Paris, France
23AP-HP, hôpital Robert Debré, service d’hématologie biologique, Paris, France

4:00 PM

Elizabeth R Macari, PhD1*, Alison Taylor, PhD1*, David Raiser, PhD2*, Kavitha Siva, PhD3*, Katherine McGrath1*, Jessica M Humphries1*, Johan Flygare, MD, PhD4*, Benjamin L Ebert, MD, PhD5 and Leonard I. Zon, M.D6

1Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA
2Harvard Medical School, Boston, MA
3Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden
4Stem Cell Center, Lund University, Lund, Sweden
5Division of Hematology, Brigham and Women's Hospital, Boston, MA
6Stem Cell Program and Division of Hematology/Oncology, Howard Hughes Medical Institute, Boston Children's Hospital/Harvard Medical School, Boston, MA

*signifies non-member of ASH