Maha Khaleel, MD^1*, Mammen Puliyel, MD¹, John Sunwoo, MS^2*, Payal Shah, MS^1*, Roberta Miyeko Kato, MD^3*, Patjanaporn Chalacheva, PhD^2*, Wanwara Thuptimdang, MS^2*, John C Wood, MD, PhD^4*, Jennie Tsao, PhD^5*, Lonnie Zeltzer, MD^5*, Richard Sposto, PhD^6*, Michael Khoo, PhD^2* and Thomas D. Coates, MD¹

¹Hematology Oncology, Children's Hospital Los Angeles, Los Angeles, CA
²Biomedical engineering, University of Southern California, Los Angeles, CA
³Pulmonology, Children's Hospital Los Angeles, Los Angeles, CA
⁴Division of Cardiology, Children's Hospital Los Angeles, Los Angeles, CA
⁵Pediatric Pain Program, University of California, Los Angeles, Los Angeles, CA
⁶Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Keck School of Medicine, Los Angeles, CA

Janet L. Kwiatkowski, MD, MSCE^1,2, Julie Kanter, MD³, Heather J. Fullerton, MD^4*, Jenifer Voeks^5*, Ellen Debenham, RN^5*, David G Brown^5*, Lynette J Brown^5* and Robert J. Adams, MD, MS^5*

¹Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
²Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
³Division of Pediatric Hematology-Oncology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC
⁴University of California San Francisco, San Francisco, CA
⁵Medical University of South Carolina, Charleston, SC

Melanie E. Fields, MD, MSCI¹, Kristin P. Guilliams, MD^2*, Dustin Ragan, PhD^3*, Cihat Eldeniz, PhD^4*, Michael Binkley^3*, Monica L. Hulbert, MD¹, Katie D. Vo, MD^5*, Robert McKinstry, MD, PhD^6*, Joshua Shimony, MD, PhD^5*, Hongyu An, PhD^7*, Andria Ford, MD, MSCI^2* and Jin-Moo Lee, MD, PhD^2*

¹Division of Pediatric Hematology/Oncology, Washington University in St. Louis, St. Louis, MO
²Department of Neurology, Washington University in St. Louis, St. Louis, MO
³Washington University in St. Louis, St. Louis, MO
⁴University of North Carolina, Chapel Hill, NC
⁵Division of Diagnostic Radiology, Washington University in St. Louis, St. Louis, MO
⁶Mallinckrodt Institute of Radiology, Washington University in St. Louis, School of Medicine, St. Louis, MO
⁷University of North Carolina School of Medicine, Chapel Hill, NC

Rakhi P. Naik, MD, MHS¹, Marguerite R. Irvin, PhD^2*, Suzanne Judd, PhD^2*, Orlando Gutierrez, MD, MMSc^2*, Neil A Zakai, MD, MSc³, Vimal K. Derebail, MD, MPH^4*, Carmen Peralta, MD, MAS^5*, Michael Lewis, MD, MBA⁶, Degui Zhi, PhD^2*, Donna Arnett, PhD, MSPH^2*, William McClellan, MD, MPH^7*, James G. Wilson, MD^8*, Alexander Reiner, MD, MSc⁹, Jeffrey Kopp, MD^10*, Cheryl Winkler, PhD^11* and Mary Cushman, MD, MSc⁶

¹Johns Hopkins University School of Medicine, Baltimore, MD
²University of Alabama at Birmingham, Birmingham, AL
³Departments of Medicine and Pathology, University of Vermont, Burlington, VT
⁴UNC Kidney Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
⁵University of California, San Francisco, San Francisco, CA
⁶University of Vermont, Burlington, VT
⁷Emory University, Atlanta, GA
⁸University of Mississippi, Jackson, MS
⁹University of Washington, Seattle, WA
¹⁰National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
¹¹National Cancer Institute, Frederick, MD

Kate Gardner, MA MBBS MRCP^1,2, Abdel Douiri, PhD^3*, Marlene Allman^2*, Emma Drasar, MBBS, PhD, MRCP, FRCPath^1,2*, Moji Awogbade¹ and Swee Lay Thein, MD, DSc^2,4

¹Department of Haematology, King's College Hospital, London, United Kingdom
²Molecular Haematology, Division of Cancer Studies, King's College London, London, United Kingdom
³Primary Care and Public Health Sciences, King's College London, London, United Kingdom
⁴National Heart, Lung and Blood Institute, Sickle Cell Branch, National Institutes of Health, Bethesda, MD

Marie Dubert, MD, MSc^1,2*, Dapa Aly Diallo, MD³, Aissata Tollo, MD^4*, Saliou Diop Sr., MD, MSc⁵, Suzanne Belinga, MD^6*, Ibrahima Sanogo, MD^4*, Odette Guifo, MD^7*, Guillaume Wamba, MD^8*, Ibrahima Diagne, MD^9*, Indou Deme LY, MD^9*, Kouakou Boidy, MD^4*, Gustave Koffi, MD^4*, Ismael Kamara, MD^4*, Youssouf Traore, MD^3*, Lucile Offredo, MSc^2*, Aymeric Menet, MD, MSc^2*, Xavier Jouven, MD, PhD^2,10* and Brigitte Ranque, MD. PhD^1,2*

¹Internal Medicine, Hopital Européen Georges Pompidou, Assistance Publique des Hopitaux de Paris, Paris, France
²UMR_S970, Paris Descartes University, Inserm, Paris, France
³Hematology, Centre de Recherche et de Lutte contre la Drepanocytose, Bamako, Mali
⁴Hematology, CHU de Yopougon, Abidjan, Cote d'Ivoire
⁵Centre National de Transfusion Sanguine, Dakar, Senegal
⁶Hematology, Centre Pasteur du Cameroun, Yaoundé, Cameroon
⁷Pediatry, Hopital Laquintinie, Douala, Cameroon
⁸Pediatry, Centre Hospitalier d'Essos, Yaoundé, Cameroon
⁹Hematology, Centre Hospitalier National d'Enfants Albert Royer, Dakar, Senegal
¹⁰Cardiology, Hopital Européen Georges Pompidou, Assistance Publique des Hopitaux de Paris, Paris, France