Jatinder K Lamba, Ph.D¹, Lata Chauhan, PhD^2*, Richard Aplenc, MD, PhD³, Maggie Skrypek, MD^4*, Jessica Pollard, MD^5,6, Todd A. Alonzo, PhD⁷, Y-C Wang^8*, Irwin D. Bernstein, MD⁹, Alan S. Gamis, MD, MPH¹⁰ and Soheil Meshinchi, MD, PhD¹¹

¹Department of Pharmacotherapy and Translational Research College of Pharmacy, University of Florida, Gainesville
²Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL
³Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
⁴Children's Hospitals and Clinic of Minnesota, Minneapolis, MN
⁵Maine Children's Cancer Program, Maine Medical Center, Scarborough, ME
⁶Department of Pediatrics, Tufts University, Boston, MA
⁷Keck School of Medicine, University of Southern California, Los Angeles, CA
⁸Children's Oncology Group, Monrovia, CA
⁹Fred Hutchinson Cancer Research Center, Seattle, WA
¹⁰Division of Hematology/Oncology/Bone Marrow Transplantation, Children's Mercy Hospitals and Clinics, Kansas City, MO
¹¹Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA

Nidhi Jyotsana, PhD^1*, Amit Sharma, PhD, MSc, BSc^1*, Anuhar Chaturvedi, PhD, MS, BPharm^2*, Colin Walsh^3*, Anitha Thomas^3*, Michaela Scherr, PhD^4*, Matthias Eder, M.D.^2*, Karin Battmer^1*, Florian Kuchenbauer, MD, PhD⁵, Sajti Laszlo^6*, Annette Barchanski^6*, Kerstin Goerlich^1*, Robert Lindner^7*, Fatih Noyan, PhD^8*, Suehs.Kurt Wolfram^9*, Denis Grote-Koska^10*, Korbinian Brand^10*, Hans-Peter Vornlocher^11*, Arnold Ganser, M.D.¹², Euan Ramsay^3*, Pieter Cullis^13* and Michael Heuser, MD¹²

¹Dept. of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
²Hematology, Hemostasis, Oncology and SCT, Hannover Medical School, Hannover, Germany
³Precision NanoSystems, Inc., Vancouver, Canada
⁴Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
⁵Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
⁶Nanotechnology Department, Laser Zentrum Hannover, Hannover, Germany
⁷Department of Cell Biology, Center of Anatomy, Hannover Medical School, Hannover, Germany
⁸Dept. of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany
⁹Clinic for Neurology, Hannover Medical School, Hannover, Germany
¹⁰Dept. of Clinical Chemistry, Hannover Medical School, Hannover, Germany
¹¹Axolabs GmbH, Kulmbach, Germany
¹²Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
¹³Precision NanoSystems, Inc., Vancouver, Germany

Xiaoyi Chen, PhD candidate^1,2*, Jason Clark^1*, Jun-lin Guan, PhD^2*, Ashish R Kumar, MBBS, PhD¹ and Yi Zheng, PhD^1,2

¹Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Cancer and Cell Biology Program, University of Cincinnati, Cincinnati, OH

Seiji Kakiuchi, MD^1*, Yosuke Minami, MD, PhD², Nobuaki Fukushima, MD^3*, Hiroshi Matsuoka, MD, PhD^1*, Tomoki Naoe, MD, Ph.D.⁴ and Hironobu Minami, MD, D.Med.Sci.^1,2*

¹Department of Medical Oncology and Hematology, Kobe University Hospital, Kobe, Japan
²Department of Transfusion Medicine and Cell Therapy, Kobe University Hospital, Kobe, Japan
³Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan
⁴National Hospital Organization Nagoya Medical Center, Nagoya, Japan

Meng Wang, MD, PhD, MRCP^1*, Ugur Eskiocak, PhD^2*, Michalis Agathokleous, PhD^2*, Stacy Yuan^2*, Charles Crawley, MD (London) FRCP FCPath¹ and Sean J. Morrison, Ph.D^3*

¹Department of Haematology, Cambridge University Hospitals, Cambridge, United Kingdom
²Children’s Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX
³UT Southwestern Medical Center, Dallas, TX

Xiaojia Niu^1*, Jianyun Zhao^1*, Jun Ma^1*, Chengzhi Xie^2*, Holly Edwards^3*, Guan Wang^1*, J. Timothy Caldwell⁴, Roland Chu^5*, Zhihong Wang, MD, PhD⁶, Hai Lin^7*, Jeffrey W Taub, MD⁸ and Yubin Ge, PhD⁹

¹Jilin University, Changchun, China
²Department of Oncology, Wayne State University, Detroit, MI
³Wayne State University, Detroit, MI
⁴MD/PhD Program, Wayne State University, Detroit, MI
⁵Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI
⁶Children's Hospital of MI, Detroit, MI
⁷The First Hospital of Jilin University, Changchun, China
⁸Department of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI
⁹Department of Oncology, Karmanos Cancer Institute, Detroit, MI

Weiguo Zhang, M.D., Ph.D.¹, Jo Ishizawa, MD, PhD^2*, Hong Mu, MD, PhD^3*, Naval Daver, MD^4,5, Vivian Ruvolo, MS^6* and Michael Andreeff, MD, PhD³

¹Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
²Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston
³Section of Molecular Hematology and Therapy, Leukemia Department, UT MD Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
⁶Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Caroline R Cantilena, BA^1*, Xin Zhao, MD, PhD^1*, Sachiko Kajigaya, PhD^1*, Neil Dunavin, MD¹, Xin Tian, PhD^2*, Stephen A. Strickland, MD³, Bipin N. Savani, MD⁴, Sanjay R. Mohan, MD^3*, Katayoun Rezvani, MD PhD⁵, Xingmin Feng, PhD¹, Danielle M. Townsley, MD¹, Minoo Battiwalla, MD, MS¹, Sawa Ito, MD¹ and Austin John Barrett, MD, FRCP, FRCPath¹

¹Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
²Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
³Vanderbilt-Ingram Cancer Center, Nashville, TN
⁴Tennessee Valley Healthcare System Veteran Affairs, Nashville, TN
⁵Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX

Kshama A. Doshi, M.S.¹, Karthika Natarajan, PhD¹, Feyruz V. Rassool, PhD², Dennis Huszar, Ph.D.³ and Maria R. Baer, MD¹

¹Greenebaum Cancer Center, University of Maryland Baltimore, Baltimore, MD
²Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD
³Oncology iMed, AstraZeneca, Waltham, MA

Dyana T Saenz^1*, Warren Fiskus, Ph.D¹, Taghi Manshouri, PhD^2*, Baohua Sun, MD, PhD¹, Stephanie Krieger^1*, Simrit Parmar, MD³, Srdan Verstovsek, MD, PhD⁴ and Kapil N. Bhalla, MD⁵

¹Department of Leukemia, MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
³Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Ayako Nogami, MD, PhD^*, Keigo Okada, MD^*, Gaku Oshikawa, MD, PhD^*, Shinya Ishida, MD^*, Hiroki Akiyama, MD^*, Yoshihiro Umezawa, MD^*, Tetsuya Kurosu, MD, PhD^* and Osamu Miura, MD, PhD

Department of Hematology, Tokyo Medical and Dental University, Tokyo, Japan

Valeria Visconte, PhD^1*, Steffan T. Nawrocki, Ph.D.², Kevin R. Kelly, MD, PhD³, Yingchun Han, MD^1*, Anthony Possemato^4*, Sean Beausoleil^4*, Aziz Nazha, MD⁵, Jaroslaw P. Maciejewski, MD, Ph.D.¹, Hetty E. Carraway, MD, MBA⁶, Anjali S. Advani, MD⁶, Mikkael A. Sekeres, MD, MS⁶ and Jennifer S. Carew, Ph.D.¹

¹Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²CTRC Institute for Drug Development, University of Texas Health Science Center at San Antonio, San Antonio, TX
³University of Southern California Keck School of Medicine, Los Angeles, CA
⁴Cell Signaling Technologies, Danvers, MA
⁵Leukemia Program, Department of Hematology and Oncology, Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
⁶Leukemia Program, Cleveland Clinic, Cleveland, OH

Sreeja Karathedath, MSc^1*, Bharathi M Rajamani, M.Phil^2*, Savitha Varatharajan, MSc^3*, Ajay Abraham, MSc^4*, Vikram Mathews, DM⁴, Shaji R Velayudhan, PhD^5* and Poonkuzhali Balasubramanian, Ph.D⁴

¹Department of Haematology, CHRISTIAN MEDICAL COLLEGE, VELLORE, India
²Christian Medical College, Department of Haematology, VELLORE, India
³Christian Medical College, Department of Haematology, Vellore, India
⁴Department of Haematology, Christian Medical College, Vellore, India
⁵Department of Hematology, Christian Medical College, Vellore, India

Mithun Vinod Shah, MD, PhD¹, Karen S. Flatten^2*, B. Douglas Smith, MD³, Allan D. Hess, PhD³ and Scott H. Kaufmann, MD, PhD⁴

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Mayo Clinic, Rochester, MN
³Department of Oncology, Division of Hematological Malignancies, Sidney Kimmel Comprehensive Cancer Center at John Hopkins, Baltimore, MD
⁴Oncology Research, Mayo Clinic, Rochester, MN

Katrin S. Reiter, MSc^1,2,3,4*, Harald Polzer, PhD^2,3,4,5*, Christina Krupka^5,6*, Binje Vick, PhD^4,5,7,8*, Andreas Maiser^9*, Marion S. Subklewe, MD^4,5,6,10, Irmela Jeremias, MD^4,8,11*, Heinrich Leonhardt, PhD^9*, Karsten Spiekermann, MD^2,3,4,5 and Philipp A. Greif, MD^1,2,4,10

¹Department of Internal Medicine III, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany
²Clinical Cooperative Group Leukemia, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany
³German Cancer Consortium (DKTK), Heidelberg, Germany
⁴German Cancer Research Center (DKFZ), Heidelberg, Germany
⁵Department of Internal Medicine III, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany
⁶Clinical Cooperation Group Immunotherapy, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany
⁷Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany
⁸German Consortium for Translational Cancer Research (DKTK) and German Cancer Research Center (DKFZ), Munich, Germany
⁹Department of BioImaging, Ludwig-Maximilians-University, Munich, Germany
¹⁰German Cancer Consortium (DKTK), Munich, Germany
¹¹Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany

Peter Herhaus^1*, Stefan Habringer^1,2*, Kathrin Philipp-Abbrederis^1*, Tibor Vag^3*, Carlos Gerngroß^3*, Alexander Höllein^1*, Torben Altmann^4*, Catharina Müller-Thomas^1*, Julia Slotta-Huspenina^5*, Christian Peschel^1,2, Markus Schwaiger^2,3*, Hans-Jürgen Wester^2,6*, Mareike Verbeek^1*, Karsten Spiekermann^2,4, Katharina Götze^1,2 and Ulrich Keller^1,2*

¹III. Department of Internal Medicine, Hematology and Medical Oncology, Technische Universität München, Munich, Germany
²German Consortium for Translational Cancer Research (DKTK) and German Cancer Research Center (DKFZ), Munich, Germany
³Clinic for Nuclear Medicine, Technische Universität München, Munich, Germany
⁴Department of Internal Medicine III, Ludwig- Maximilians- Universität München, Munich, Germany
⁵Institute of Pathology, Technische Universität München, Munich, Germany
⁶Institute of Pharmaceutical Radiochemistry, Technische Universität München, Munich, Germany