Laurie H. Sehn, MD, MPH¹, Stefano Luminari^2,3, Christian W. Scholz⁴, Kai Hübel^5*, Antonio Salar, MD^6*, Shankara Paneesha, MD^7,8, Bjorn E Wahlin, MD, PhD⁹, Panayiotis Panayiotidis, MD¹⁰, Hui-Peng Lee, MD^11*, Ana Jiménez Ubieto^12*, Juan-Manuel Sancho, MD, PhD^13*, Tae Min Kim, MD, PhD^14*, Eva Domingo Domenech, MD^15*, Takahiro Kumode, MD, PhD^16*, Christina Poh, MD¹⁷, Catherine Thieblemont, MD¹⁸, Dries Deeren^19*, Edwin de Wit^20*, Michael Arbushites^21*, Marie-Laure Casadebaig^20* and Marek Trneny, MD, CSc²²

¹BC Cancer Centre for Lymphoid Cancer and The University of British Columbia, Vancouver, BC, Canada
²Surgical, Medical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Reggio Emilia, Italy
³Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
⁴Vivantes Klinikum Am Urban, Berlin, Germany
⁵University of Cologne and Faculty of Medicine and University Hospital of Cologne, Cologne, Germany
⁶Hospital del Mar-IMIM, Barcelona, Spain
⁷University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
⁸University of Birmingham, Birmingham, United Kingdom
⁹Karolinska University Hospital, Stockholm, Sweden
¹⁰National and Kapodistrian University of Athens Medical School, General Hospital LAIKO, Athens, Greece
¹¹Flinders Medical Centre, Adelaide, Australia
¹²Servicio de Hematologia, Hospital 12 de Octubre, Madrid, Spain
¹³ICO-IJC-Hospital Germans Trias i Pujol, Baldona, Universitat Autonoma de Bacrcelona, Barcelona, Spain
¹⁴Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea, Republic of (South)
¹⁵Institut Català d'Oncologia, Hospital Duran I Reynals, IDIBELL, Barcelona, Spain
¹⁶Kindai University, Osaka, Japan
¹⁷Fred Hutchinson Cancer Center/ University of Washington, Seattle, WA
¹⁸Assistance Publique-Hôpitaux de Paris, Saint-Hospital, Saint-Paris Cité Université, Paris, France
¹⁹AZ Delta General Hospital, Roeselare, Belgium
²⁰Incyte International Biosciences, Sarl Morges, Switzerland
²¹Incyte Corporation, Wilmington, DE
²²First Faculty of Medicine, Charles University and General Hospital, Prague, Czech Republic

Laurent Martin^1*, Darko Maric^2*, Salam Idriss^3,4*, Marine Delamare^5,6*, Amandine Le Roy^5,7*, Nada Maaziz, PharmD^8*, Amandine Caillaud^7*, Karim Si-Tayeb^7*, Florence Robriquet^5,7*, Marion Lenglet^5,7*, Lucie Erceau^5,7*, Christine Bellanné-Chantelot^9*, Isabelle Plo, PhD^10*, Bernard Aral, MD, phD^11*, Céline Garrec, MD^12*, Fabrice Airaud^13*, Clara Gianfermi^14*, Vincent Antunes^2*, Anna Keppner^15*, Sarah Mathilda Vincent^15*, Alexis Desfontaine^16*, Nina Modé^17*, Fabien Laporte^7*, Anne Gaignerie^18*, Caroline Chariau^18*, Isabelle Leray^18*, Coline Rogue^18*, Laurent David^19,20*, Richard Redon^7*, Stephane Bezieau, MD, phD^12*, Lamisse Mansour^21,22*, Frederic Galacteros, Prof, MD^23,24*, Thibault Maillet^25*, Marlène Pasquet, MD^26*, Pierre Cougoul^27*, Anne-Marie Nloga^28*, Claude Gardin, MD, PhD^29,30*, Corinne Guitton, MD^31*, Viviane Dubruille, MD^32*, Vannina Giacobbi-Milet^33*, Thierry Leblanc^34*, Zuhre Kaya^35*, Denis Semama^36*, Chloe James, MD, PhD^37*, Serge Carillo^38*, Marlène Ochmann^39*, Anders Waage, MD, PhD^40*, Erwan Mortier^41,42,43*, Mike Maillasson^41,42,43*, Agnès Quéméner^41,42*, Holger Cario^44,45*, Radek C. Skoda, MD⁴⁶, Yaël Zermati^17,47*, David Hoogewijs^2,48*, Alexandre Marchand^1*, Francois Girodon, MD, PhD^49* and Betty Gardie, PhD^50*

¹Laboratoire Antidopage Français (LADF), Université Paris-Saclay, Orsay, France
²Section of Medicine, Department of Endocrinology, Metabolism and Cardiovascular System, University of Fribourg, Fribourg, Switzerland
³EPHE, PSL Université, Paris, France, Paris, France
⁴Nantes Université, CHU Nantes, CNRS, INSERM, l’institut du thorax,, Nantes, France
⁵EPHE, PSL Université, Paris, France
⁶5 Nantes Université, CHU Nantes, CNRS, INSERM, l’institut du thorax, Nantes, France
⁷Nantes Université, CHU Nantes, CNRS, INSERM, l’institut du thorax, Nantes, France
⁸CHU Dijon, Laboratoire de génétique moléculaire et chromosomique, Dijon, FRA
⁹INSERM UMR1287, Gustave Roussy, Villejuif, France
¹⁰INSERM UMR1287, Gustave Roussy, Paris-Saclay University, Villejuif, France
¹¹CHU Dijon, Laboratoire de génétique moléculaire et chromosomique, Dijon, France
¹²Centre Hospitalier Universitaire De Nantes, Nantes, FRA
¹³Service de Génétique Médicale, CHU De Nantes, Nantes, FRA
¹⁴Laboratoire Antidopage Français (LADF, Université Paris-Saclay, Orsay, France
¹⁵SSection of Medicine, Department of Endocrinology, Metabolism and Cardiovascular System, University of Fribourg, Fribourg, Switzerland
¹⁶Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, CRSA, paris, France
¹⁷Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, CRSA, Paris, France
¹⁸Nantes Université, CHU Nantes, CNRS, Inserm, BioCore, Nantes, France
¹⁹Nantes Université, CHU Nantes, CNRS, Inserm, BioCore,, Nantes, France
²⁰Nantes Université, CHU Nantes, Inserm, CR2TI, Nantes, France
²¹Département de Biochimie-Biologie Moléculaire, Pharmacologie, Génétique Médicale, and Red Cell Disease Referral Center-UMGGR AP-HP, Hôpitaux Universitaires Henri Mondor, Créteil, France
²²Université Paris-Est Créteil, IMRB Equipe Pirenne, Laboratoire d'excellence LABEX GRex,, Créteil, France
²³Sickle Cell Referral Center, Henri-Mondor University Hospital- UPEC, AP-HP, Creteil, France
²⁴GHU Henri Mondor, AP-HP, Creteil, France
²⁵Unité de Recherche Clinique, Centre Jospitalier de Macon, Macon, France
²⁶Department of Pediatric Hematology and Oncology, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France
²⁷Toulouse University Hospital, Toulouse, France
²⁸Hématologie Clinique- Hop. Avicenne AP-HP HUPSSD, Bobigny, France
²⁹Hôpital Avicenne, Hematology Department, AP-HP, Bobigny, France
³⁰UFR SMBH, Sorbonne Paris Nord University, Bobigny, France
³¹Pediatrics and Sickle Cell Center, Bicêtre Hospital, AP-HP, Le Kremlin-Bicêtre, France
³²Hematology department, Hôtel Dieu, CHU de Nantes, Nantes, France
³³Onco-hématologie pédiatrique, CHU du Mans, Mans, France
³⁴Service d’Hematologie et d’Immunologie Pédiatrique, Centre de Reference Aplasies Medullaires Acquises et Constitutionnelles, Hôpital Robert-Debré, Assistance Publique Hôpitaux de Paris and Université Paris Cité, Paris, France
³⁵Pediatric hematology, Gazi University, Ankara, Turkey
³⁶Réanimation néonatale, Service de pédiatrie, CHU Dijon, Dijon, France
³⁷Laboratory of Hematology, Bordeaux University Hospital, Pessac, France
³⁸Service d’hématologie, CHU Orléans, Orléans, France
³⁹Laboratoire de Cytologie Clinique et Cytogénétique, LBMR néoplasies myéloprolifératives, CHU Caremeau, Nîmes, France
⁴⁰Institute of Clinical and Molecular Medicine, Norwegian University of Science and Technology, and Research Department, St Olavs Hospital, Trondheim, Norway
⁴¹Nantes Université, CNRS, Inserm, CRCI2NA, Nantes, France
⁴²LabEX IGO, Immuno-Onco-Greffe, Nantes, France
⁴³Nantes Université, Centre Hospitalo-Universitaire (CHU) Nantes, Nantes, France
⁴⁴Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany
⁴⁵Center for Rare Hematopoietic Disorders and Immunodeficiencies (ZSHI Ulm),, Ulm University Medical Center, Ulm, Germany
⁴⁶Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX
⁴⁷Laboratoire d’Excellence GR-Ex, Paris, France
⁴⁸National Center of Competence in Research “Kidney.CH”, Zurich, Switzerland
⁴⁹Laboratory of Biological Hematology, University Hospital of Dijon, Dijon, France
⁵⁰Ecole Pratique des Hautes Etudes, EPHE, Université de Nantes, CNRS, INSERM,, Nantes, France

Francis Couturaud, MD, PhD^1*, Olivier Sanchez^2*, Nicolas Meneveau^3*, Laurent Bertoletti, MD^4*, Gilles Pernod^5*, Isabelle Mahe, MD, PhD⁶, Emilie Presles^7*, Philippe Girard^8*, Cécile Tromeur^9*, Patrick Mismetti^10*, Silvy Laporte, MS, PhD^11* and Christophe Leroyer^12*

¹Univ Brest, INSERM U1304-GETBO, CIC INSERM 1412; FCRIN INNOVTE network, CHU de Brest, France
²Université Paris Cité, Service de Pneumologie et Soins Intensifs, Hôpital Européen Georges Pompidou, APHP, Paris, France; INSERM UMR_S1140, Innovations Thérapeutiques en Hémostase, Laboratoire de Chirurgie expérimentale, Fondation Alain Carpentier, Paris;, Paris, France
³University Hospital Besançon, 25000 Besançon; FCRIN INNOVTE network, Besançon, France
⁴CHU De St-Etienne; FCRIN INNOVTE network, St-Etienne, FRA
⁵University Grenoble Alpes, CNRS/TIMC-IMAG UMR 5525/Themas; FCRIN INNOVTE network, Grenoble, France
⁶Internal Medicine department, Paris Cité University, Louis Mourier Hospital , APHP, Inserm UMR-S1140, Innovations Thérapeutiques en Hémostase, Paris; F-CRIN INNOVTE Network, France, Colombes, France
⁷CHU Saint-Etienne; FCRIN INNOVTE network, Saint Etienne, FRA
⁸Département de Pneumologie, Institut Mutualiste Montsouris, Paris; FCRIN INNOVTE Network, Paris, France
⁹Univ Brest, INSERM U1304-GETBO, CIC INSERM 1412, CHU Brest; FCRIN INNOVTE network, Brest, France
¹⁰Département Thoracique, Institut Mutualiste Montsouris; FCRIN INNOVTE network, Paris, France
¹¹Univ. Jean Monnet, Mines Saint-Etienne, INSERM, U1059, SAINBIOSE, CHU Saint-Etienne; Service de pharmacologie clinique, F-42023, Saint-Etienne; F-CRIN INNOVTE Network, SAINT-ETIENNE, FRA
¹²Department of Internal Medicine and Chest Diseases; FCRIN INNOVTE network, Brest, FRA

Jihyun Song, PhD, Soo Jin Kim, MS^* and Josef T. Prchal, MD

Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT

Françoise Bernaudin, MD¹, Suzanne Verlhac, MD^2*, Elisabeth Ducros-Miralles^3*, Cecile Arnaud, MD^4*, Isabelle Genty, MD^5*, Marie Petras, MD^6*, Catherine Paillard, MD, PHD^7*, Thuret Isabelle, MD^8*, Annie Kamdem, MD^9*, Corinne Pondarré, MD, PHD^10*, Giovanna Cannas, MD^11*, Christelle Chantalat-Auger, MD^12*, Gonzalo De Luna, MD^13*, Benoit Meunier, MD^14*, Nadia Firah, MD^15*, Sophie Pertuisel, MD^15*, Corinne Guitton, MD^16*, Laure Joseph, MD^17*, Florence Missud, MD^18*, Claire Pluchart, MD^19*, Monique Elmaleh, MD^20*, Benedicte Neven, MD, Ph.D^21*, Marie Angoso, MD^22*, Pierre Frange, MD, PHD^23*, Karima Yakouben, MD^24*, Bénédicte Bruno, MD^25*, Nathalie Dhédin, MD^26*, Jean-Hugues Dalle, MD, PHD²⁷, Regis Peffault de Latour, MD, PhD^28*, Catherine Belozertseva, MD, PhD^29* and Camille Jung, MD, PHD^30*

¹Referral Center for Sickle Cell Disease/ Clinical Research Department, Hôpital Intercommunal de Créteil, Université Paris-Est, Creteil, France
²Medical Imagery, Robert Debré Paris Hospital, Referral Center For Sickle Cell Disease, Paris, France
³Neuropsychiatry department, Hopital Intercommunal de Créteil, Créteil, France
⁴Referral Center for Sickle Cell Disease, Hopital Intercommunal de Créteil, Creteil, France
⁵Referral Center for Sickle Cell Disease, Internal Medicine, Centre Hospitalier Intercommunal de Créteil, Creteil, France
⁶Referral Center for Sickle Cell Disease, CHU Guadeloupe, Pointe à Pitre, Guadeloupe
⁷CHRU Hautepierre, Strasbourg, FRA
⁸Hemato-Pediatrics, la Timone Hospital, CHU, Marseille, France
⁹Referral Center for Sickle Cell Disease, Intercommunal Creteil Hospital, Creteil, France
¹⁰Referral Center For Sickle Cell Disease, University Paris-Est, CréTeil, France
¹¹Hopital Edouard Herriot, Lyon, France
¹²Department of Internal Medicine, Bicetre Teaching Hospital, AP-HP, Universite Pa, Le Kremlin Bicetre, France
¹³Sickle Cell Referral Center, Department of Internal Medicine, Henri-Mondor University Hospital- UPEC, AP-HP, Creteil, France
¹⁴Hemapheresis, Hopitaux Universitaires de Marseille, Marseille, France
¹⁵Pediatrics Department, Centre Hospitalier de Pau, Pau, France
¹⁶Pediatrics and Sickle Cell Center, Bicêtre Hospital, AP-HP, Le Kremlin-Bicêtre, France
¹⁷Biotherapy Department, French National Sickle Cell Referral Center, Hopital Necker, AP-HP, Paris, France
¹⁸Referral Center For Sickle Cell Disease, Robert Debré Hospital, AP-HP, Paris, France
¹⁹Pediatric Oncology, CHU de Reims, Reims, France
²⁰Medical Imagery, Robert Debré Hospital, Paris, France
²¹BMT unit, Hopital Necker (APHP), Paris, France
²²CHU Bordeaux, bordeaux, France
²³Necker Hospital, Paris, France
²⁴Department of Pediatric Hematology and Immunology, University Hospital Robert Debré, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
²⁵Pediatric Hematology Department, Lille University Hospital, Lille, France
²⁶Service d'Hématologie Adolescents et Jeunes Adultes, Hôpital Saint-Louis, PARIS, France
²⁷Hôpital Robert-Debré, GHU APHP Nord Université de Paris Cité, Paris, France
²⁸Hôpital Saint-Louis, Université Paris Cité, Paris, France
²⁹Clinical Research Department, Centre Hospitalier Intercommunal de Créteil, Créteil, France
³⁰Clinical Research Department, CHIC Hospital, Créteil, France

Timothy S. Fenske, MD¹, Xin Victoria Wang, PhD^2*, Brian G. Till, MD³, Kristie A. Blum, MD⁴, Matthew Lunning, DO⁵, Hillard M. Lazarus, MD⁶, Paul A.S. Fishkin, MD⁷, Lale Kostakoglu Shields, MD, MPH^8*, David W. Scott, MBChB, PhD⁹, Ann S. LaCasce, MD¹⁰, Patrick B. Johnston, MD, PhD^11*, Amanda F. Cashen, MD¹², Leslie L. Popplewell, MD, MPH¹³, Robert M. Dean, MD¹⁴, Nausheen Ahmed, MD¹⁵, Nirav N. Shah, MD¹⁶, Nina D. Wagner-Johnston, MD¹⁷, Boyu Hu, MD¹⁸, Bhagirathbhai R. Dholaria, MBBS¹⁹, Richard F. Little, MD, MPH²⁰, Jonathan W. Friedberg, MD²¹, John P. Leonard, MD²² and Brad S. Kahl, MD¹²

¹Medical College of Wisconsin, Milwaukee, WI
²Dana-Farber Cancer Institute / ECOG-ACRIN Biostatistics, Bostin, MA
³Fred Hutchinson Cancer Center, University of Washington, Seattle, WA
⁴Emory University / Winship Cancer Institute, Atlanta, GA
⁵University of Nebraska Medical Center, Omaha, NE
⁶Case Western Reserve University, Cleveland, OH
⁷Illinois CancerCare, P.C., Peoria, IL
⁸NYU Langone Health, New York, NY
⁹Centre for Lymphoid Cancer, British Columbia Cancer, Vancouver, BC, Canada
¹⁰Dana-Farber Cancer Institute, Boston, MA
¹¹Mayo Clinic, Rochester, MN
¹²Washington University School of Medicine, Saint Louis, MO
¹³City of Hope Cancer Treatment Center, Atlanta, GA
¹⁴Case Comprehensive Cancer Center, Cleveland Clinic Taussig Cancer Institute and Case Western Reserve University, Cleveland, OH
¹⁵University of Kansas Cancer Center, Kansas City, KS
¹⁶Medical College of Wisconsin, Brookfield, WI
¹⁷Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Baltimore, MD
¹⁸Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
¹⁹Vanderbilt University Medical Center, Nashville, TN
²⁰National Cancer Institute, National Institutes of Health, Washington, DC
²¹Wilmot Cancer Institute, University of Rochester, Rochester, NY
²²Weill Cornell Medicine, New York, NY